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Wyszukujesz frazę "venom" wg kryterium: Temat


Wyświetlanie 1-3 z 3
Tytuł:
Medicinal value of animal venom for treatment of Cancer in Humans - A Review
Autorzy:
Pal, Partha
Roy, Spandita
Chattopadhyay, Swagata
Pal, Tapan Kumar
Powiązania:
https://bibliotekanauki.pl/articles/1193921.pdf
Data publikacji:
2015
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Cancer
animal venom
anticancer drug
medicinal value
Opis:
Since cancer is one of the leading causes death worldwide and there is an urgent need to find better treatment. In recent years remarkable progress has been made towards the understanding of proposed hallmarks of cancer development and treatment. Anticancer drug developments from natural resources are ventured throughout the world. Venoms of several animal species including snake, scorpion, frog, spider etc. and their active components in the form of peptides, enzymes etc. have shown promising therapeutic potential against cancer. In the present review, the anticancer potential of venoms as well as their biochemical derivatives from some vertebrates like snake or frog or some venomous arthropods like scorpion, honey bee, wasps, beetles, caterpillars, ants, centipedes and spiders has been discussed. Some of these molecules are in the clinical trials and may find their way towards anticancer drug development in the near future. The recognition that cancer is fundamentally a genetic disease has opened enormous opportunities for preventing and treating the disease and most of the molecular biological based treatment are cost effective. The search for alternative economical and natural sources for cancer medicines is of utmost need for the future in combating this dreadful disease that is spreading at fast rate in the present era.
Źródło:
World Scientific News; 2015, 22; 91-107
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Anti-Snake venom Activities of the leaf extracts of Asystasia gangetica (L) and Newbouldia leavis (p. Beauv)
Autorzy:
Enenebeaku, C. K.
Umerie, S. C.
Nwankwo, M. U.
Enenebeaku, U. E.
Powiązania:
https://bibliotekanauki.pl/articles/1112887.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Asystasia gangetica
Medicinal plants
Naja melanoleuca
Newbouldia leavis
Snake Venom
Opis:
The leaf extracts of two medicinal plants Asystasia gangetica (L) and Newboulia leavis (p. Beauv) were assessed for anti-snake venom activity in vivo using mice. The result of the phytochemical analysis revealed that the two plants contain flavonoids, glycosides, saponins, tannins and alkaloids. The methanolic extracts of the two plants A. gangetica (L) and N. leavis (p. Beauv) significantly (p< 0.05) neutralized the Naja melanoleuca venom-induced lethality activity in the mice. The extracts (flavonoids, tannins and saponins) of the two plants also showed significant (p<0.05) neutralization of the venom–induced lethality activity in mice. The work confirmed that Asystasia gangetica and Newbouldia leavis possess significant anti-venom activity and can therefore be used in the treatment of snake bites.
Źródło:
World News of Natural Sciences; 2018, 16; 33-41
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of previous scorpion bite on the action of local anaesthetic agents: A case report
Autorzy:
Hariharan, Uma
Tripathi, Sonali
Powiązania:
https://bibliotekanauki.pl/articles/1065187.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Bromage Scale
Country-side
Local Anaesthetic Action
Neurotoxic Venom
Scorpion Bite
Subarachnoid block
Opis:
Scorpion bites are a relatively common phenomenon in the Indian subcontinent, especially in the countryside. Past history of scorpion bite, as a relevant and significant factor, during pre-anesthetic evaluation is infrequently taken, when patient comes for unrelated medical/surgical conditions. We hereby report a case of failure of subarachnoid block in an adult male, posted for lower limb orthopedic surgery. A 45-year-old, ASA grade 1 male patient was posted for elective right tibial nailing. Single-shot subarachnoid block was planned for the procedure, which failed. Sub-arachnoid block was repeated and again, there were no signs of sensory or motor blockade. At this point, on specific enquiry, the patient gave history of scorpion bite twice; first, at the age of 32 years, and the second time, about 10 months back. Thereafter, it was decided to give standard balanced general anaesthesia for the procedure. The surgery lasted for 90 min and was uneventful. Postoperatively, neurological examination of the lower limbs revealed incomplete sensory block by pin prick method and grade I motor block on Bromage scale (just able to flex/move knees). Scorpion venom may be responsible for the development of resistance to the action of local anesthetic agents. This case report discusses the possible correlations between scorpion bite and the failure of sub-arachnoid block.
Źródło:
World Scientific News; 2019, 120, 2; 291-295
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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