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Wyświetlanie 1-2 z 2
Tytuł:
Helicobacter pylori infection: from biology to clinical features
Autorzy:
Kolasińska, Karolina
Kwiatkowski, Stanisław
Knap, Bartosz
Czerwiński, Grzegorz
Poniewierka, Elżbieta
Waszczuk, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1165561.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Helicobacter pylori
MALT lymphoma
gastric cancer
peptic ulcer disease
Opis:
The discovery of bacterium Helicobacter pylori and the association of its occurrence with gastritis and peptic ulcer disease, was one of the most significant events of the 20th century. Almost 40 years have passed since that event, but we are still far from fully understanding of the impact of H. pylori infection on the human body. It is confirmed, that the infection causes chronic gastritis, which increases the risk of diseases such as: duodenal and/or gastric ulcer, gastric cancer and gastric MALT lymphoma. Nevertheless, constantly appear new studies linking H. pylori with many other disorders, often not directly related to the digestive system. Cardiovascular, neurological, hematological, dermatological, metabolic and also gynecological diseases are in sphere of assumptions. The authors of the following work attempted to select key information available in the medical literature on the discovery of H. pylori, epidemiology and pathophysiology of infection, as well as diseases to which it predisposes and the latest methods of eradication.
Źródło:
World Scientific News; 2018, 107; 171-184
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ameliorative Effect of Ethanolic Extract of Laportea aestuans (L.) Chew on Gastric Oxidative Damage in Aspirin - Induced Gastric Ulcer in Male Rats
Autorzy:
Onadeko, Akinwande
Akinola, Olusegun
Powiązania:
https://bibliotekanauki.pl/articles/1839808.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Gastric Ulcer
Oxidative Stress
Cimetedine
Phytochemicals
Aspirin
Laportea aestuans
Opis:
Non-steroidal anti-inflammatory drugs (NSAIDs) are connected with the generation of free radicals and one of its adverse effects is gastric ulceration. Ulceration was induced orally using aspirin. Twenty-four male Wistar rats were used for this study (120-150g). Rats were divided into 6 groups with each group containing 4 rats. Rats were pre-treated orally with cimetidine, a reference drug. Group 1 rats orally received 1% gum acacia solution as the control group, Group 2 rats orally administered 25 mg/kg aspirin and served as the ulcerated, untreated group, rats in groups 3 and 4 were pre-treated orally with 200 mg/kg and 400 mg/kg respectively for 3 days while rats in groups 5 and 6 were pre-treated orally with 50 mg/kg cimetidine and 50 mg/kg catechin respectively for 3 days. The result of this study shows that the ulcerated, untreated rats showed increased concentrations of gastric volume with a concomitant decrease in protein concentration compared to the control group, cimetidine and catechin reversed these observations. Activities of glutathione, catalase were decreased in the ulcerated, untreated group but pre-treatment with different doses, cimetidine and catechin reversed these observations. In conclusion, the ethanoic extract of L. aestuans can be said to be used as an anti-ulcerogenic agent against aspirin-induced gastric ulcer which is due to the presence of phytochemicals in the plant.
Źródło:
World News of Natural Sciences; 2021, 39; 86-94
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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