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    Wyświetlanie 1-14 z 14
    Tytuł:
    Synthesis, Antimicrobial and Antioxidant Activities of Some Naphthalene - Containing Hydrazone Derivatives
    Autorzy:
    Sivasankari, S.
    Rubala mary, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1112540.pdf
    Data publikacji:
    2018
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    antibiotic
    antimicrobial activities
    antioxidant activities
    hydrazone
    naphthalene
    Opis:
    The inevitable consequence of the widespread use of antimicrobial agents has been the emergence of antibiotic resistant pathogens. This necessitates an ever-increasing search for new drugs. In an effort to develop antimicrobial agents, a series of hydrazone 2-6-derivatives were synthesized. These were characterized on the basis of physical and spectroscopic data, and were evaluated for their antimicrobial activity against various bacterial and fungal strains using the disc diffusion method and nutrient agar media. The antioxidant activities of the products were also evaluated. Our data showed that many derivatives have promising activities as antioxidant agents.
    Źródło:
    World News of Natural Sciences; 2018, 18, 2; 124-132
    2543-5426
    Pojawia się w:
    World News of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, spectroscopic characterization and antimicrobial evaluation of some (E)-N-(4-substitutedbenzylidene)-4-fluorobenzenesulfonamides
    Autorzy:
    Jayanthi, P.
    Jesu Retna Raj, G.
    Sekar, M.
    Thanikachalam, V.
    Powiązania:
    https://bibliotekanauki.pl/articles/1113828.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    4-fluorobenzenesulfonamide
    Bauer-Kirby
    IR spectra
    NMR spectra
    antimicrobial activities
    Opis:
    In the present study, six numbers of Schiff bases (1-6) have been synthesized by the condensation of 4-fluorobenzenesulfonamide and substituted aromatic aldehyde. The purities of these Schiff bases have been checked by their physical constants, IR, 1H NMR and 13CNMR spectral data. The antimicrobial activities of these Schiff bases have been evaluated using Bauer-Kirby method.
    Źródło:
    World News of Natural Sciences; 2017, 13; 101-112
    2543-5426
    Pojawia się w:
    World News of Natural Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cu2+/Zeolite catalyzed synthesis and evaluation of antimicrobial activities of some chalcones
    Autorzy:
    Thirunarayanan, G.
    Kumar, N. Dinesh
    Powiązania:
    https://bibliotekanauki.pl/articles/1179609.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Antimicrobial activities
    Aryl chalcones
    Cu2+/Zeolite
    IR and NMR spectra
    Opis:
    Some aryl chalcones have been synthesized by Cu2+/Zeolite catalyzed aldol condensation of aryl methyl ketones and substituted benzaldehydes under microwave irradiation conditions. The yields of the synthesized chalcones are more than 85%. These chalcones were characterized by their physical constants and spectroscopic data. The antimicrobial activities of synthesized chalcones were studied by Bauer-Kirby disc diffusion method.
    Źródło:
    World Scientific News; 2017, 74; 251-266
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microwave assisted synthesis, spectral studies and antimicrobial activities of some 2′,4′-difluorophenyl chalcones
    Autorzy:
    Vijayakumar, S.
    Arulkumaran, R.
    Sundararajan, R.
    Sakthinathan, S. P.
    Suresh, R.
    Kamalakkannan, D.
    Ranganathan, K.
    Sathiyamoorthy, K.
    Mala, V.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/412217.pdf
    Data publikacji:
    2013
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Microwave irradiation
    Aldol condensation
    Hydroxyapatite
    Spectral correlations
    Hammett σ constants
    antimicrobial activities
    Opis:
    Some 2′,4′-difluorophenyl chalcones have been synthesized under microwave irradiation using aldol condensation between 2,4-difluoroacetophenone and substituted benzaldehydes using catalytic amount of hydroxyapatite. The yields of the chalcones are more than 85 %. The purities of these synthesized chalcones were examined by their physical constants and spectroscopic data. The UV absorption maxima (λmax, nm), infrared stretches (ν, cm-1) of CO, fingerprint region of CHip/op, CH=CHop, C=Cop modes, NMR chemical shifts (δ, ppm) of vinyl proton, carbon and carbonyl carbons have been assigned and correlated with Hammett substituent constants, F and R parameters using single and multi-regression analysis. From the statistical analysis the effect of substituent on the above spectral frequencies can be discussed. The antimicrobial activities of these synthesized chalcones have been screened using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2013, 9, 1; 68-86
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Aryl Chalcones as Efficient Precursors for Deriving Oxazine: Solvent-free Synthesis and Antimicrobial Activities of some Oxazine-2-amines
    Autorzy:
    Thirunarayanan, G.
    Sundararajan, R.
    Arulkumaran, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/411627.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Oxazine amines
    Chalcones
    fly-ash
    H2SO4
    Environmentally benign reaction
    antimicrobial activities
    Opis:
    A series of some oxazine derivatives has been synthesised by fly-ash:H2SO4 catalyzed solvent-free cyclization of aryl chalcones and urea under microwave irradiation. The yields of the oxazines were more than 85 %. The synthesised oxazines were characterized by their physical constants, analytical and spectroscopic data. The antimicrobial activities of these oxazines have been studied using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 4; 82-97
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bioactive 3-methyl-2,6-diarylpiperidin-4-one, oxime and its copper(II) complex
    Autorzy:
    Thirunarayanan, G.
    Lakshmanan, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/1070862.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Antimicrobial activities
    Copper(II) complex
    Disc diffusion
    Drug dilution
    Piperidine-4-one
    Piperidine-4-oneoxime
    Opis:
    namely 3-methyl-2,6-diphenylpiperidin-4-oneoxime and copper(II) complex of this oxime was prepared by literature procedure. The purities of these ketone, oxime and copper complex was analyzed by physico-chemical and spectroscopic methods reported in the literature. The physicochemical analysis results confirmed that the structure of the complex was distorted octahedral. The antimicrobial activities of these substrates such as ketone, oxime and its copper complex were investigated using Bauer-Kirby disc diffusion technique against several antimicrobes by measuring the mm of zones of inhibitions. Further these activities were concluded using drug dilution method. From the analysis report, the copper (II) complex of the oxime shows significant antimicrobial activities against their antimicrobial stains. The oxime shows moderate antimicrobial activity. The ketone shows satisfactory antibacterial and antifungal activities against their stains in both disc diffusion and drug dilution methods.
    Źródło:
    World Scientific News; 2019, 123; 124-140
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spectral correlations and antimicrobial activities of some 1-pyrenyl chalcones
    Autorzy:
    Arulkumaran, R.
    Vijayakumar, S.
    Sundararajan, R.
    Sakthinathan, S.P.
    Kamalakkannan, D.
    Suresh, R.
    Ranganathan, K.
    Rajakumar, P.R.
    Powiązania:
    https://bibliotekanauki.pl/articles/411776.pdf
    Data publikacji:
    2013
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    substituted styryl 1-pyrenyl ketones
    UV spectra
    IR spectra
    NMR spectra
    substituent effects
    antimicrobial activities
    Opis:
    A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2013, 5; 21-38
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spectral correlation analysis and antimicrobial activities of some 2,4-dimethoxy phenyl chalcones
    Autorzy:
    Joseph, S. J.
    Arulkumaran, R.
    Kamalakkannan, D.
    Sakthinathan, S. P.
    Sundararajan, R.
    Suresh, R.
    Vijayakumar, S.
    Ranganathan, K.
    Kalyanasundaram, N.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/412661.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    substituted styryl 2
    4-dimethoxy phenyl ketones
    UV spectra
    IR spectra
    NMR spectra
    substituent effects
    antimicrobial activities
    Opis:
    A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 4; 48-65
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Solid acidic Bentonite/FeCl3 catalysed solvent-free cyclization of some aryl enones: Synthesis and assessment of antimicrobial potentials of some aryl pyrazolines
    Autorzy:
    Thirunarayanan, G.
    Dineshkumar, N.
    Rajarajan, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1076026.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    1
    3
    5-Substituted pyrazolines
    Antimicrobial activities
    Bentonite/FeCl3
    IR and NMR Spectra
    Solvent-free synthesis
    Opis:
    Some aryl pyrazolines including 3-(substituted phenyl)-5-(naphthalen-1-yl)-1-phenyl-4,5-dihydro-1H-pyrazoles were prepared by microwave irradiation promoted cyclization of aryl enones and phenylhydrazine in the presence of solid acidic bentonite/FeCl3 catalyst under solvent-free conditions. In this cyclization the obtained yields are more than 75%. The structural analysis of these pyrazoline derivatives were confirmed through analytical and spectral techniques. The effect of catalyst and solvent on this cyclization also investigated through the obtained yields. The antimicrobial activities of these pyrazoline derivatives were assessed through measurement of mm of zone of inhibition against their micro stains using well known Bauer-Kirby disc diffusion method.
    Źródło:
    World Scientific News; 2019, 117; 14-28
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Assessment of substituent effects and antimicrobial activities of some 2ʹ,5ʹ-dimethyl phenyl chalcones
    Autorzy:
    Joseph, S. J.
    Kamalakkannan, D.
    Arulkumaran, R.
    Sakthinathan, S. P.
    Suresh, R.
    Sundararajan, R.
    Vijayakumar, S.
    Ranganathan, K.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/412597.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    substituted styryl 2
    5ʹ-dimethyl phenyl chalcones
    UV spectra
    IR spectra
    NMR spectra
    substituent effects
    antimicrobial activities
    Opis:
    Some 2ʹ,5ʹ-dimethyl phenyl chalcones have been synthesized by Crossed-Aldol condensation between 2,5-dimethyl acetophenone and various substituted benzaldehydes using catalytic amount of sodium hydroxide and ethanol. The yields of the chalcones are more than 93 %. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 5; 99-123
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spectral correlation analysis of Hammett substituent constants and biological activities of some (E)-1-(4-phenoxyphenyl)-3-phenylprop-2-en-1-ones
    Autorzy:
    Kalyanasundaram, N.
    Sakthinathan, S. P.
    Suresh, R.
    Kamalakkannan, D.
    Joseph, S. J.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/412539.pdf
    Data publikacji:
    2014
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    substituted styryl 4-phenoxyphenylketones
    UV-spectra
    IR spectra
    NMR spectra
    Hammett constants
    substituent effects
    regression analysis and antimicrobial activities
    Opis:
    A series of aryl chalcones have been synthesized from 4-phenoxyacetophonone with various substituted benzaldehydes. The purity of all chalcones has been checked using their physical constants and spectral data. These spectral data have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied. The single parameter correlation with few Hammett constants and F and R parameters gave satisfactory correlation coefficients whereas all multiple correlations gave satisfactory correlation coefficients with Resonance, Field and Swain-Lupton’s parameters. The antimicrobial activities of all chalcones have been studied using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2014, 9; 23-47
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, spectral correlation analysis and evaluation of antimicrobial activities of some (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-ones
    Autorzy:
    Sathiyendiran, V.
    Balaji, S.
    Senbagam, R.
    Vijayakumar, R.
    Manikandan, V.
    Rajarajan, M.
    Muthuvel, I.
    Markandan, R.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/1031849.pdf
    Data publikacji:
    2020
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    4-dimethylthiazol enones
    Antimicrobial activities
    Crossed-Aldol condensation
    E-2
    IR and NMR spectra
    Spectral correlation analysis
    Substituent effects
    UV
    Opis:
    In this work, an attempt was made to synthesized (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one by cross-aldol condensation reaction of 5′-acetyl-2,4-dimethylthiazole with various substituted Benz aldehyde in the presence base (sodium hydroxide). The synthesized (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one derivative was characterized by physical constants, UV, FT-IR, 1H-NMR & 13C-NMR spectral data. All the observed spectral data of substituted (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one compounds have been correlated with Hammett substituent constants(σ, σ+, σI & σR) and F and R parameters using single and multi-linear regression analyses and studied for their anti-microbial activities and compared with the standard drugs (Ciprofloxacin). Some compound of the series exhibited promising anti-microbial activity compared to standard drugs (Ciprofloxacin).
    Źródło:
    World Scientific News; 2020, 141; 66-90
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, effect of substituents and antimicrobial activities of some 4-bromophenyl chalcones
    Autorzy:
    Vijayakumar, S.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/1191238.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones
    UV spectra
    IR spectra
    NMR spectra
    Substituent effects
    Antimicrobial activities
    Opis:
    Elven (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones are formed using sodium hydroxide catalyzed Aldol condensation between 4-bromoacetophenone and substituted benzaldehyde. The production of these chalcone compounds are above 90%. These α, β unsaturated ketones were specified by their physical constants and spectral data (UV, IR, 1H and 13C-NMR). Hammett substituted constants (σ, σ+, σI & σR and F and R parameters have been used for correlating the spectral values of these α, β unsaturated ketones by using single and multi-linear regression analysis. The impacts of substituents on the spectral data have been known on statistical analysis. By using Bauer-Kirby method the anti-microbial activities of these (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones compounds are estimated.
    Źródło:
    World Scientific News; 2016, 54; 132-152
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Thionylchloride catalyzed aldol condensation: Synthesis, spectral correlation and antibacterial activities of some 3,5-dichloro-2-hydroxyphenyl chalcones
    Autorzy:
    Arulkumaran, R.
    Vijayakumar, S.
    Sundararajan, R.
    Sakthinathan, S. P.
    Kamalakkannan, D.
    Suresh, R.
    Ranganathan, K.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/411825.pdf
    Data publikacji:
    2012
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    chlorek tionylu
    widma IR i NMR
    korelacja Hammeta
    aktywność antybakteryjna
    wpływ podstawników
    styrylo 3,5-dichloro-2-hydroksy fenylo ketony
    thionyl chloride
    styryl 3,5-dichloro-2-hydroxyphenyl ketones
    IR and NMR spectra
    Hammett correlation
    substituent effects
    antimicrobial activities
    Opis:
    A series of substituted styryl 3,5-dichloro-2-hydroxyphenyl ketones [1-(3, 5-dichloro-2-hydroxy)- 3-phenylprop-2-en-1-one] were synthesized using thionyl chloride assisted Crossed Aldol reaction. The yields of chalcones were more than 80%. The synthesized chalcones were characterized by analytical and spectroscopic data. From the spectroscopic data the group frequencies were correlated with Hammett substituent constants, F and R parameters. From the results of statistical analysis the effect of substituents were discussed. The antibacterial activities of these chalcones have been evaluated using Bauer-Kirby method.
    Źródło:
    International Letters of Chemistry, Physics and Astronomy; 2012, 4; 17-38
    2299-3843
    Pojawia się w:
    International Letters of Chemistry, Physics and Astronomy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-14 z 14

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