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Tytuł:
Infection Control in the Post-Antibiotic Era
Autorzy:
Upla, Peter
Ukpanah, Mfonido
Gbadeyan, Femi
Uyi, Gerard
Dauda, Odenye
Powiązania:
https://bibliotekanauki.pl/articles/1114109.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Infection control
antibiotic resistance
hand hygiene
nosocomial infection
tetratogenic infection
transposons
Opis:
Antibiotic resistance by pathogenic microorganisms has become a major clinical and public health problem in the 21st century. Countries across the world are faced with restricted healthcare resources, high demand for modern drugs and increasing antimicrobial resistance. This escalation in antibiotic resistance is attributed to the misuse and over use of antibiotics, poor isolation practices and long hospital stay of patients who then become susceptible to nosocomial infection. The misuse and overuse of antibiotics is now generating resistance to almost all classes. However, it is pertinent to emphasize that even with the pervasive nature of antibiotic resistance worldwide; infections acquired by patients in the hospital must be treated. Thus, this review article proposes some control options and recommendations to protect us against resistant bacterial strains.
Źródło:
World News of Natural Sciences; 2017, 11; 37-44
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The assessment of knowledge about viral hepatitis among Polish society
Autorzy:
Ślusarz, Krystian
Szczygieł, Katarzyna
Sobala-Szczygieł, Barbara
Jaroszewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1065218.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
HAV infection
HBV infection
HCV infection
knowledge assessment
viral hepatitis A
viral hepatitis B
viral hepatitis C
Opis:
Viral hepatitis is caused by viruses, the most important of which are hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV). New discoveries and new therapeutic options result in better and better results of treatment. However, the public's awareness of the occurrence of these diseases and the detection of infections as soon as possible is still important, what is associated with better outcomes. In order to assess the basic knowledge about viral hepatitis among Polish society, an online survey spread throughout Poland and covering mainly young people was created. 2205 responses were collected and analyzed. On the basis of the results obtained, it can be concluded that Polish youth have little knowledge about viral hepatitis, what is associated with less awareness of the possibility of infection.
Źródło:
World Scientific News; 2019, 135; 1-13
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of cholera toxin in Vibrio cholerae infection in humans - a review
Autorzy:
Pal, P.
Powiązania:
https://bibliotekanauki.pl/articles/10765.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
cholera
toxin
Vibrio cholerae
human infection
bacteriophage
Opis:
Vibrio cholerae, the causative agent of Asiatic cholera, is a gram-negative motile bacterial species acquired via oral ingestion of contaminated food or water sources. Cholera has spread from the Indian subcontinent where it is endemic to involve nearly the whole world seven times during the past 185 years. V. cholerae serogroup O1, biotype El Tor, has moved from Asia to cause pandemic disease in Africa and South America during the past 35 years. A new serogroup, O139, appeared in south Asia in 1992, has become endemic there, and threatens to start the next pandemic. The facultative human pathogen V. cholerae represents a paradigm that evolved from environmental non-pathogenic strains by acquisition of virulence genes. The major virulence factors of V. cholerae, cholera toxin (CTX) encoded by the ctxAB genes residing in the genome of filamentous lysogenic bacteriophage (CTXɸ) and toxin coregulated pilus (TCP) encoded by vibrio pathogenicity island (VPI). CTX, a potent stimulator of adenylate cyclase, causes the intestine to secrete watery fluid rich in sodium, bicarbonate, and potassium, in volumes far exceeding the intestinal absorptive capacity, by ADP-ribosylation of the alpha subunit of the GTP-binding protein. Thus intestinal infection with V. cholerae results in the loss of large volumes of watery stool, leading to severe and rapidly progressing dehydration and shock. Without adequate and appropriate rehydration therapy, severe cholera kills about half of affected individuals. Today, cholera still remains a burden mainly for underdeveloped countries, which cannot afford to establish or to maintain necessary hygienic and medical facilities. During the last three decades, intensive research has been undertaken to unravel the virulence properties and to study the epidemiology of this significant human pathogen. This review provides an overview of the role of CTX in the occurrence of this disease in humans.
Źródło:
International Letters of Natural Sciences; 2014, 17
2300-9675
Pojawia się w:
International Letters of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of the knowledge about HIV-infectious materials in Poland
Autorzy:
Ślusarz, Krystian
Sobala-Szczygieł, Barbara
Jaroszewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1076602.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
HIV infection
HIV infectious materials
Polska
survey
Opis:
Malignancies were one of the earliest diagnosed manifestations that resulted in the description of acquired immunodeficiency syndrome (AIDS). Most cancers in AIDS patients are associated with coinfection with oncogenic viruses. Knowledge and public awareness about HIV infectious materials are important elements in preventing the spread of HIV infections. The aim of the study was to assess the knowledge about HIV infectious materials among three populations in Poland. A Poland-wide on-line survey was conducted and 2205 anonymous answers were analysed. Almost half of the answers came from students, of which 40% were medical students.
Źródło:
World News of Natural Sciences; 2019, 27; 38-49
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ethnobotanical Survey of Medicinal Plants Used in Treating Viral Infection in Saki West Local Government Area, Oyo State, Nigeria
Autorzy:
Fingesi, U. I.
Buochuama, A.
Abdulrahman, Q. A.
Powiązania:
https://bibliotekanauki.pl/articles/1112778.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
ethnobotanical survey
herbs
medicinal plant
viral infection
Opis:
Most indigenous people have acquired expertise in the use of medicinal plants, but information on the utilization of the medicinal plants are poorly documented. Thus, this study deals with the ethnobotanical survey of medicinal plants used in treating viral infections in Saki West Local Government Area, Oyo State. Data was collected using structured questionnaires and oral interviews to acquire information from selected members of Saki West Local Government Area. A total of sixty (60) structured questionnaires were given randomly to respondents in the selected villages in the study area. Data were analyzed using descriptive statistics. The finding shows that the majority of the respondents were females (61.7%). Moreover, 50 % of the respondents were from the age group of 31 to 40 (also the largest group). In addition, a majority (88.3%) of the respondents were married, and only a few (16.7%) had no formal education. Furthermore, the major occupation of the respondents was herb selling (35.0%). The findings on the various plant parts utilized for herbal medicine indicated that the leaves, stem bark and whole root were the most commonly used parts. Most of the respondents also prepared herbal medicine by decoction. What is more, oral ingestion (drinking) was found to be the most (70.0%) preferred mode of administration in the study area. Finally, the major problem encountered while acquiring medicinal plants was wild animal threat. This work indicated that there is a need for an ethnobotanical survey in every state of the nation on the medicinal plants used in the treatment of viral infection.
Źródło:
World News of Natural Sciences; 2018, 17; 89-101
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Markovian Epidemic Queueing Model with Exposed, Infection and Vaccination based on Treatment
Autorzy:
Singh, Ram
Preeti, Preeti
Raina, Ather Aziz
Powiązania:
https://bibliotekanauki.pl/articles/1166188.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Epidemic Model
Infection
Markov model
Runge kutta method
Vaccination
Opis:
In this investigation, an epidemic Markov queueing model with alert, infection, vaccination and death has been considered. The main focus of this work is on the vaccination to provide the infection in a population. Healthy person may be affected from some disease that may cause death. The vaccination is the power tool for the prevention of the diseases spreading over the population size. Healthy person become alert when symptoms of the disease can be seen on them and the alert may be injected due to more infection. The provision of vaccination is provided in both alert and infected stages. The transition rates as followed by exponential distribution. A Markov model is developed by using inflow and outflow transition rates of the model. The transient state probabilities are evaluated by solving the transient state equations by using runge kutta method which are further used for calculating the model performances. A numerical illustration is also provided to validate the model.
Źródło:
World Scientific News; 2018, 106; 141-150
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Emerging and detection of Dengue viral infection in Sri Lanka
Autorzy:
Amarakoon, A. A. D. Gayathri Upeksha
Powiązania:
https://bibliotekanauki.pl/articles/1188088.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
IgG
RT-PCR
IgM
acute infection
Aedes mosquitos
Opis:
Emerging of dengue infection has increased dramatically in Sri Lanka in recent years. Initial infection with a particular serotype is known as primary infection which is usually asymptomatic or mild disease manifestations. Although cross reactive T cells and cross reactive antibodies have been shown to contribute to disease pathogenesis, these mechanisms alone do not explain the immune - pathological mechanisms leading to severe infection. However, this study has suggested that antigen antibody detection and viral RNA detection in host blood contribute to the occurrence of disease. Therefore, it is important to further investigate the quality of dengue specific immune responses and confirmation of dengue RNA content in patients with acute severe dengue and asymptomatic dengue infection.
Źródło:
World Scientific News; 2016, 56; 97-109
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bacteriuria of women of child bearing age
Autorzy:
Bakpolor, V. R.
Powiązania:
https://bibliotekanauki.pl/articles/1111864.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antibiotics susceptibility
Asymptomatic bacteriuria
Bacterial isolates
Prevalence
Urinary tract infection
Opis:
Urinary tract infection (UTI) is one of the most common diseases encountered worldwide. In this study, urine samples were collected from thirty women of child bearing age (18-25 years) to determine the prevalence of bacteriuria, as well as the presence of pus cells and white blood cells which are signs of infection. The urine microscopy result revealed that 7 (23.3%) of the sample had greater than 10 leucocytes per high power field. Only four of the samples had a significant number of pus cells. The bacteria count recorded ranged from 25 cfu/0.001 ml to 276 cfu/0.001 ml. Of the samples, 13 were positive for bacteriuria having bacterial count greater than 100 cfu/0.001 ml. The bacteria isolates include Klebsiella spp. (3.8%), Streptococcus spp. (2.5%). Escherichia coli (62.5%) and Staphylococcus spp. (21.2%). Of these, Klebsiella spp. was the least prevalent and Escherichia coli had the highest number of occurrence. These organisms were very sensitive to Ciprofloxacin, Pefloxacin, Zinnacef and Gentamycin according to the antimicrobial susceptibility test carried out. Ciprofloxacin was found to be the most effective antibiotics against all the bacterial isolates. Here, zones of inhibition ranged from 15 mm (Streptococcus spp.) to 20 mm (Escherichia coli). All the bacterial isolates were resistant to Amoxicillin, with zones of inhibition between 11 (Klebsiella spp., Escherichia coli, Staphylococcus spp.) and 13 mm (Streptococcus spp.). Since the prevalence of asymptomatic bacteriuria is high, early diagnosis and proper treatment is necessary in order to prevent it from becoming symptomatic.
Źródło:
World News of Natural Sciences; 2018, 20; 255-266
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibacterial activity of modified zinc oxide nanoparticles against Pseudomonas aeruginosa isolates of burn infections
Autorzy:
Aysa, Noor Hadi
Salman, Halah Dawood
Powiązania:
https://bibliotekanauki.pl/articles/1191368.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antimicrobial activity
Pseudomonas aeruginosa
ZnO
burn infection
nanoparticles
surface modification
Opis:
In this research antimicrobial activity of nanoparticles ZnO on perilous bacteria such as Pseudomonas aeruginosa was evaluated. P. aeruginosa is important pathogen that caused burn wound infections as it is multi-drug resistant and has several virulence factors. Fifteen samples of P. aeruginosa were collected from patients who suffering from Burn infections in Al-Hilla teaching hospital burn unit with the age range between (7-80) years old for both genders. After collecting burn samples, the diagnosis and characterization were performed by culturing and biochemical tests. ZnO NPs were synthesized by chemical method, Zinc oxide nanoparticles are well-known to be one of the multifunctional inorganic compounds which are widely used in medical applications. This study aims to prepare ZnO nanoparticles with particle size ranging from 23-29  nm. In the present study, surface modification of ZnO nanoparticles was performed, and influence of modification of the structure and morphological properties was investigated. The resulting nanoparticles were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force (AFM). Zinc oxide nanoparticles with the average diameter of about 29 nm were modified with an oleic acid to exert more compatibility. From the results obtained it is suggested that modified ZnO-nanoparticles could be used effectively in safety environmental and medical applications. Antibacterial activity for nanoparticle ZnO against P. aeruginosa isolates was measured by: Agar Diffusion Technique and Minimum Inhibitory Concentration (MIC)/Minimum bactericidal Concentration (MBC) with microdilution. The best zone of inhibition was (35.5mm) at a concentration of 40 μg/ml of nano-ZnO in one strain of P. aeruginosa while the lowest inhibition zone was (16 mm) at a concentration of 20 μg/ml of nano ZnO in one strain also. In addition, all P. aeruginosa isolates were completely inhibited at the concentration of 3.7 μg/ml of nano-ZnO (MIC) but no significant antibacterial activity was observed at concentrations less than 1.8 μg/ml of nano-ZnO and the (MBC) was same as MIC (3.7 μg/ml) for all P.aeruginosa isolates.
Źródło:
World Scientific News; 2016, 33; 1-14
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Improvement in CD4 cells counts in newly diagnosed HIV infected Cameroonian patients under HARRT is counterbalanced by the mild deleterious effects of antiretroviral therapy on liver function: a longitudinal study
Autorzy:
Pradel, Kojom Loick
Kelly, Tuileu Tchamake Sorelle
Vanessa, Assokom Eliane
Dorgelesse, Kouemo Motse Francine
Lugarde, Kamgain Mawabo
Powiązania:
https://bibliotekanauki.pl/articles/1111854.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
CD4 cells count
Douala
HAART
HIV infection
transaminases levels
Opis:
Human immunodeficiency virus (HIV) infection still is a worldwide public health concern, but especially so in Cameroon. Still, the health of HIV-infected people has greatly improved following the introduction of highly active antiretroviral therapy (HAART). Conversely, some authors reported the occurrence of side effects. Unfortunately, data on the topic are scarce in Cameroon. This study aimed at investigating the impact of HAART on liver function in newly diagnosed HIV-infected people. An 18-month longitudinal study was carried out in a health facility in the town of Douala, Cameroon. Investigative methods relied on a questionnaire approach, clinical and biological analyses and medical records exploitation. A total of 107 patients aged 18-45 years old were included in the study. Most participants were females (94, 87.9%) and aged 30-40 years (60, 56.1%). A higher significant fraction of patients had CD4 lymphocytes counts less than 200 cells/mm3 (42, 39.3%) at baseline. We recorded a 1.5-fold increment in the CD4 lymphocytes counts over the follow up period (P-value < 0.0001). Indeed, globally, a significant increasing in ALT level was recorded over follow up. There is a critical need for paying attention to liver function in people living with HIV/AIDS and under therapy.
Źródło:
World News of Natural Sciences; 2018, 20; 215-225
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of nutrition in the management and control of malaria infection: a review
Autorzy:
Onukogu, S. C.
Ibrahim, J.
Ogwuche, R. A.
Jaiyeola, T. O.
Adiaha, M. S.
Powiązania:
https://bibliotekanauki.pl/articles/1165192.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Effective nutrition
Immune system
Malaria infection
Malnutrition
Poverty
Sub-Sahara African
Opis:
A review of the contribution of nutrition in management and control of Malaria was conducted. Nutrition has been confirmed as one factors that can be used to suppress the effect of malaria infection before clinical treatment is received by the patient. For the body to function normally, its nutritional demand must be met in the right proportions. Diet rich in vitamins, minerals, micronutrients are required for the metabolic functioning of the body, hence effective or adequate nutrition has health benefits to the human body. Living on quality diet has a way of improving the body defense mechanism against infectious diseases such as malaria.
Źródło:
World Scientific News; 2018, 107; 58-71
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The multiple HPV infections and their possible significance in predicting the risk of the cervical cancer
Autorzy:
Kożańska, Aleksandra
Pisarska, Justyna
Baldy-Chudzik, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1070878.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
HPV co-infection
PCR-RFLP
Real-Time PCR
cervical cancer
human papillomavirus
Opis:
Infections with human papillomavirus (HPV) are detected frequently. The occurrence of persistent infection with oncogenic HPV type associates with the development of cervical cancer. However, the part of HPV infections consist of the multiple viral types. The influence of HPV co-infections on the risk of the development of cervical cancer is not clear, but the occurrence of more than one viral type seems to increase the risk of advanced lesions of the uterine cervix. Additionally, possible interactions (both positive and negative) between particular HPV types in co-infections may influence the risk of the lesions progression. Although, the issue of HPV co-infections is not well known, the previous scientific reports make that the introduction of the molecular methods, allowing the identification not only single but also multiple HPV infections, in routine diagnostics seem to be important. Here, we present the PCR-RFLP and Real-Time PCR methods as the useful tools in the diagnostics of HPV infections.
Źródło:
World Scientific News; 2019, 123; 192-207
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Oral cavity diseases in HIV infected patients
Autorzy:
Łanowy, Patrycja
Bichalski, Miłosz
Dzindzio, Jakub
Blaszkowska, Maria
Jaroszewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1165319.pdf
Data publikacji:
2018
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
AIDS
HIV infection
HIV manifestation
Kaposi’s sarcoma
candidiasis
hairy leukoplakia
oral lesions
Opis:
Oral cavity lesions are amongst the earliest manifestations of HIV-infection. Thorough examination of oral cavity as well as awareness of associations between specific symptoms and HIV-infection can lead to early diagnosis of this life-long disease. Consequently, early diagnosis of HIV infection allows for prompt introduction of antiretroviral therapy allowing to improve patients’ quality of life, their life expectancy but also reducing the risk of transmission. Therefore, raising awareness on oral cavity disorders suggestive of HIV-infection among general physicians and dentists is of a great importance. In this article we described the most common oral cavity manifestations associated with HIV infection including: oral candidiasis, hairy leukoplakia and Kaposi’s sarcoma in detail.
Źródło:
World Scientific News; 2018, 107; 84-96
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biomedical Waste Management Status in Two Hospitals of Gulbarga City, Karnataka, India
Autorzy:
Murli, Jadesh V.
Kavya, K. S.
Shivkumar, D. S.
Powiązania:
https://bibliotekanauki.pl/articles/1193004.pdf
Data publikacji:
2016
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Biomedical waste
Collection and Transportation of wastes
Hospital
Infection
Liners
Management and Handling Rules
WHO
non-infectious wastes
Opis:
The proper management of biomedical waste has become a worldwide humanitarian topic today. Although hazards of poor management of biomedical waste have aroused the concern worldwide over, especially in the light of its far –reaching effects on human, health and the environment. Now it is well established fact that there are many adverse and harmful effects to the environment including human being which are caused by the “HOSPITAL WASTE” generated during the patient care. Hospital waste is a potential health hazards to the care workers, public, flora, fauna of the area. The problems of the waste disposal in the hospitals and other health care institutions have become issues of increasing concerns. This research article is to survey the practice of biomedical waste such as collection, storage, transportation, and disposal along with the amount of biomedical waste generated in two Hospitals of Gulbarga. The proper management methods have been employed in Government hospital. In Basaveshwara hospital there is no proper segregation of waste at the source of generation and all the wards don’t contain all the liners. In both the hospitals waste collected and disposed daily. It is highly desirable for a Hospital Administrator to know the weak points in the chain of waste management so that these could be addressed appropriately. Keeping this in view, the present study was conducted to assess generation and management of biomedical waste in Government General Hospital and Basaveshwara Hospital.
Źródło:
World Scientific News; 2016, 31; 59-87
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Structural analyses of AC4 protein of Sri Lankan cassava mosaic virus
Autorzy:
Gupta, S.
Ganguli, S.
Basu, P.
Datta, A.
Powiązania:
https://bibliotekanauki.pl/articles/11568.pdf
Data publikacji:
2015
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
structural analysis
AC4 protein
cassava mosaic virus
RNA silencing
viral infection
viral suppressor
geminivirus
post transcriptional gene silencing
Opis:
RNA silencing is one of the important phenomenon in plant defense mechanism, it actively protect host plants against viral infections. Existing viruses must have developed counter defense strategies to survive this arms race. Such counter defense strategy is the viral silencing suppressor (VSRs) which have been reported to directly interfere with the various steps leading to the interference of viral RNAs. Most identified VSRs are multifunctional, besides being RNA-silencing suppressors, they often perform essential roles by functioning as coat proteins, helper components for viral transmission, replicases and movement proteins, proteases or transcriptional regulators. One such identified VSR is AC4 of Sri Lankan cassava mosaic virus strain. Trivial knowledge about the structure –function relationship of this VSR leads to this work, where we focus on the structure generation by modelling to identify the mode of interactions with the various effector molecules of the silencing pathways. Structural analyses have been performed to screen interacting residues. Results indicate conserved structural features which signify propensity of functional interactions and further shows that this VSR can be a potent tool for the analysis of RNA silencing mechanisms and the relationships between different silencing pathways and VSRs.
Źródło:
International Letters of Natural Sciences; 2015, 06
2300-9675
Pojawia się w:
International Letters of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
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