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Wyszukujesz frazę "Acquired immunodeficiency syndrome (AIDS)" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Adherence to Highly Active Antiretrovial Therapy Among Patients Receiving Treatment in Imo State University Teaching, Hospital, Orlu, Nigeria
Autorzy:
Nwokorie, I. C.
Ezeama, M. C.
Nwanjo, H. U.
Powiązania:
https://bibliotekanauki.pl/articles/1839410.pdf
Data publikacji:
2021
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Acquired immunodeficiency syndrome (AIDS)
Adherence
Human Immunodeficiency Virus (HIV)
Imo State
Opis:
This study investigated Adherence to Highly Active Antiretroviral Therapy (HAART) among HIV positive patients receiving treatment in Imo State University Teaching Hospital Orlu. A prospective descriptive survey was adopted which involved hundred and fifty-three respondents (153) and twenty-five (25) clinic staff working in the Community Medicine of the Hospital. The instrument for data collection was structured questionnaire. Data were analyzed using SPSS version 25. Findings revealed that majority of the respondents 87(82.9%) agreed that they adhered strictly to their drugs prescriptions as ordered. 80(76.2%) of the respondents had no complaints about side effects, while 20 (95.2%) of the respondents reported poverty as one the challenges experienced for non-compliance to adherence, 12(57.1%) of them indicated forgetfulness as a major factor affecting their compliance to the HAART regimen, which is below the adherence level of ≥ 95% needed for HIV infected patients to reach full viral suppression. The study concluded that there is a fair adherence level of 87(82.9%) of HIV positive patients attending HAART clinic in IMSUTH but need to improve to reach ≥ 95% to enable HAART patients achieve full viral suppression. Health personal should emphasis more on teaching HAART regimen to HIV infected patients and also should be more focus to achieve more results.
Źródło:
World Scientific News; 2021, 161; 90-110
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Identifying overlapping phylogenetic and geographic roots of HIV - 1 evolution through computational analyses
Autorzy:
Singh, P.K.
Banik, R.
Chakraborty, H.J.
Das, S.G.
Ganguli, S.
Datta, A.
Powiązania:
https://bibliotekanauki.pl/articles/11359.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
phylogenetic root
geographic root
evolution
computational analysis
HIV-1
genome
recombinant strain
AIDS
human disease
acquired immunodeficiency syndrome zob.AIDS
acquired immune deficiency syndrome zob.AIDS
Opis:
HIV-1 or Human Immuno Deficiency Virus-1 is the main causative agent of Acquired Immuno Deficiency Syndrome (AIDS). Human host infected with HIV - 1 extensively harbours many viral variants but very little is known about the difference in pattern[17] of evolution of phylogenetic lineages of HIV-1 non recombinant, normal inter subtype recombinant and main two specific recombinant forms of HIV-1 i.e., Circulating Recombinant Forms (CRFs) and Unique Recombinant Forms (URFs). This study is mainly concerned with study of the difference in evolutionary lineages of non-recombinant and recombinant sequences of HIV-1 genome sequences and identification of geographically rich areas which has reported high degree of HIV-1 occurrence and variety. Total 1550 HIV-1 genome sequences were obtained from HIV Los Alamos Database. The sequences were aligned using MAFFT (Multiple Alignment using Fast Fourier Transform) web server tool. Alignment was carried out using 10 different set of alignment parameter values. After alignment the aligned file was used for constructing N-J phylogenetic tree using Clustal X2 tool. Phylogenetic analysis was performed keeping in mind the category to which the sequence belongs. Upon analysis it was observed that the clade containing the probable ancestor belongs remained constant in all cases of different alignment values. Non recombinant isolates, inter subtype recombinants, CRFs, URFs all followed different patterns of evolution. Non recombinant sequences were found geographically specific and subtype specific to some extent whereas, normal recombinants were subtype specific and less geographically specific. CRFs showed variation among the pattern of their evolution. At some instances the sequences occurred as sister taxa of non-recombinant or normal inter subtype recombinant sequences, while at some instances as sister taxa of other CRFs where they were geographically specific. Three CRFs existed as completely diverged sequences. URFs were four in number; two of them were Indian isolates of while other two were Japanese isolates. URFs were found to be totally geographically specific. Geography wise high rate of variation was observed in India and Japan as these two countries had sequences belonging to all of the above categories. Cameroon and South Africa have very large number isolates and a considerable amount of genetic variation among isolates but they lack URFs.
Źródło:
International Letters of Natural Sciences; 2014, 02
2300-9675
Pojawia się w:
International Letters of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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