Wszystkie pola: Hotspots - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: A Review on the Ichthyofauna of Nagaland, North-East India
Autorzy:: Ezung, Sophiya
Kechu, Metevinu
Longkumer, Sentiyanger
Jamir, Ajungla
Pankaj, Pranay Punj
Powiązania:: https://bibliotekanauki.pl/articles/1031847.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: Cyprinidae
Ichthyofaunal hotspots
Nagaland
North-East India
lotic and lentic habitat
Opis:: North-East India is a region with many native freshwater fishes and is one of the ichthyofaunal hotspots of the world. According to the current study, a total of 197 valid species of fish has been reported from Nagaland, India, which consists of 10 orders, 26 families and 87 genera, from various lotic and lentic habitats. Family Cyprinidae consists of the highest record of 75 fish species and Osphronemidae, Gobidae, Scianenidae and Chacidae families with the lowest record of one fish species in each.
Źródło:: World News of Natural Sciences; 2020, 30, 2; 104-116
2543-5426
Pojawia się w:: World News of Natural Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Dengue virus (NS2B/NS3 protease) protein engineering. Part I: An automated design for hotspots stability and site-specific mutations by using HotSpot Wizard 3.0 tool
Autorzy:: Lahiri, Madhumita
Ghosh, Ipsita
Talukdar, Partha
Talapatra, Soumendra Nath
Powiązania:: https://bibliotekanauki.pl/articles/1062840.pdf
Data publikacji:: 2019
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: HotSpot Wizard
NS2B/NS3 protease
Non-structural protein
computational tool
protein engineering
Opis:: The non-structural dengue virus (DNV) protein, DNV-2 NS2B/NS3 protease is a combination of two proteins as 2B and 3 and these two proteins in complex replicate faster during dengue fever. The objective of the present study was to detect hot spots and design of smart libraries for engineering protein stability, substrate specificity, tunnels and cavities as well as suitable mutability position of studied protein by using an online tool, HotSpot Wizard (version 3.0). The prediction results were obtained in output interface for functional hot spots, stability hot spots (structural flexibility), correlated hot spots and stability hot spots (sequence consensus) from the sequence string. It is concluded that the prediction of pocket and mutability of this protein can easily be identified the structural alternation especially in disease diagnosis and space for ligand binding site in pocket for the potential of new drug design. Moreover, this computational prediction is suggested to compare with experimental hotspots for studied protein in relation to therapeutic efficacies, which are lacking to prevent viral infection.
Źródło:: World Scientific News; 2019, 127, 3; 177-190
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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