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    Wyświetlanie 1-6 z 6
    Tytuł:
    Wrazliwosc na ketokonazol szczepow Candida zasiedlajacych ontocenozy przewodu pokarmowego dzieci
    Autorzy:
    Horwatt-Bozyczko, E
    Kurnatowski, M.
    Wasowska-Krolikowska, K.
    Kurnatowska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/836934.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    zasiedlanie
    ontocenozy
    ketokonazol
    grzyby
    przewod pokarmowy
    Candida
    parazytologia lekarska
    dzieci
    wrazliwosc na antybiotyki
    szczepy grzybow
    Opis:
    The study included 52 children. During endoscopy the contents of oesophagus, stomach and duodenum were collected with catheters, and additionally washings from the oral cavity and anal swabs or samples of faeces. Materials were inoculated on Sabouraud's media. The axenic strains of fungi were identified using own methods and others tests (API 20C, API 20C AUX). The activity of ketoconazole (K) was measured against 100 strains of Candida: C. albicans (91 strains), C. kefyr (4), C. famata (2). C. tropicalis (1), C. guilliermondii (1), C. glabrata (1). The strains susceptibility to K (RO4 1400 Janssen) was estimated with the own system based on the dose - response curves; the minimal inhibitory concentration (MIC) values were canculated. The low values of MIC indicate high susceptibility to K of examined Candida strains.
    Źródło:
    Annals of Parasitology; 2001, 47, 4; 929-933
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wrażliwość na ketokonazol szczepów Candida zasiedlających ontocenozy przewodu pokarmowego dzieci
    THE SUSCEPTIBILITY TO KETOCONAZOLE OF CANDIDA STRAINS ISOLATED FROM THE DIGESTIVE TRACT ONTOCENOSES IN CHILDREN*
    Autorzy:
    Horwatt-Bożyczko, E.
    Kurnatowski, M.
    Wąsowska-Królikowska, K.
    Kurnatowska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148254.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    zasiedlanie
    ontocenozy
    ketokonazol
    grzyby
    przewod pokarmowy
    Candida
    parazytologia lekarska
    dzieci
    wrazliwosc na antybiotyki
    szczepy grzybow
    Opis:
    The study included 52 children. During endoscopy the contents of oesophagus, stomach and duodenum were collected with catheters, and additionally washings from the oral cavity and anal swabs or samples of faeces. Materials were inoculated on Sabouraud's media. The axenic strains of fungi were identified using own methods and others tests (API 20C, API 20C AUX). The activity of ketoconazole (K) was measured against 100 strains of Candida: C. albicans (91 strains), C. kefyr (4), C. famata (2). C. tropicalis (1), C. guilliermondii (1), C. glabrata (1). The strains susceptibility to K (RO4 1400 Janssen) was estimated with the own system based on the dose - response curves; the minimal inhibitory concentration (MIC) values were canculated. The low values of MIC indicate high susceptibility to K of examined Candida strains.
    Źródło:
    Wiadomości Parazytologiczne; 2001, 47, 4; 929-933
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Badania nad wrażliwością Trichomonas hominis na czynniki abiotyczne. 1. Wstępna ocena przeżywalności wiciowców w wybranych mediach w warunkach in vitro
    Studies on the susceptibility of Trichomonas hominis to some abiotic factors. I. Preliminary assessment of antitrichomonal activity of selected compounds in vitro
    Autorzy:
    Chomicz, L.
    Żebrowska, J.
    Zawadzki, P.
    Myjak, P.
    Perkowski, K.
    Rebandel, H.
    Kazimierczuk, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/2147385.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    wrazliwosc na leki
    in vitro
    przezywalnosc
    parazytologia lekarska
    leki przeciwpasozytnicze
    rzesistek jelitowy
    wiciowce
    czynniki abiotyczne
    Trichomonas hominis
    Opis:
    The flagellate Trichomonas hominis is often identified in human diarrheic stools. Because of the fecal-oral transmission rout, infection with 7. hominis is more frequently reported in children than in adults. Although infections with the trichomonads in some world regions are as often as with Giardia, no prevention and optimal treatment are defined. The purpose of our in vitro studies was to examine susceptibility of T. hominis to a newly synthesized imidazole derivative — 1-metylo-2-(2,4-dinitrobenzylotio)-1H-imidazol — P27; in order to make a comparison between this new and previously known compounds, chlorhexidine and metronidazole were used. The protozoans derived from the diarrheic stool of adult patient were grown on the liquid Pahm medium and subcultured twice a week. Assays of trichomonad cultures were incubated with one of the following substances: chlorhexidine, metronidazole or P27. For each compound, two different concentrations were applied. After 24h exposition, an antitrichomonal effect of the above substances was assessed, namely a quantity of the surviving trichomonads was microscopically determined and compared with that observed in control cultures. The protozoans showed different susceptibility, depending on kind and concentration of tested compound. In comparison to the control cultures, the reduction in number of surviving protozoans appeared in the assays with metronidazole, chlorhexidine and P27 (to 63%, 52% and 8.7%, respectively). The highest in vitro susceptibility of 7. hominis was revealed to a new imidazole derivative P27. The obtained results allow us to suppose that the further studies in this field will be very helpful for explaining the mechanisms of the antitrichomonal activity of the tested compounds as well as for assessment of the influence of various abiotic factors.
    Źródło:
    Wiadomości Parazytologiczne; 2004, 50, 3; 405-409
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Badania nad wrazliwoscia Trichomonas hominis na czynniki abiotyczne. 1. Wstepna ocena przezywalnosci wiciowcow w wybranych mediach w warunkach in vitro
    Autorzy:
    Chomicz, L.
    Zebrowska, J.
    Zawadzki, P.
    Myjak, P.
    Perkowski, K.
    Rebandel, H.
    Kazimierczuk, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/839687.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    wrazliwosc na leki
    in vitro
    przezywalnosc
    parazytologia lekarska
    leki przeciwpasozytnicze
    rzesistek jelitowy
    wiciowce
    czynniki abiotyczne
    Trichomonas hominis
    Źródło:
    Annals of Parasitology; 2004, 50, 3; 405-409
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
    Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
    Autorzy:
    Kurnatowska, A.K.
    Kwasniewska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/840111.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    mikonazol
    wrazliwosc na leki
    itrakonazol
    Candida
    parazytologia lekarska
    leczenie szpitalne
    pacjenci
    leki przeciwgrzybicze
    szczepy grzybow
    leczenie ambulatoryjne
    grzybice
    Źródło:
    Annals of Parasitology; 2009, 55, 4; 415-423
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
    Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
    Autorzy:
    Kurnatowska, A.K.
    Kwaśniewska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2143561.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    mikonazol
    wrazliwosc na leki
    itrakonazol
    Candida
    parazytologia lekarska
    leczenie szpitalne
    pacjenci
    leki przeciwgrzybicze
    szczepy grzybow
    leczenie ambulatoryjne
    grzybice
    Opis:
    It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
    Źródło:
    Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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