- Tytuł:
-
2,2’-dihydroksy-1,1’-binaftyl (BINOL) i jego pochodne. Wybrane syntezy i zastosowanie. Część. II
2,2’-dihydroxy-1,1’-binaphthyl (BINOL) and its derivatives : selected synthesis methods and applications. Part II - Autorzy:
- Krasowska, D.
- Powiązania:
- https://bibliotekanauki.pl/articles/172097.pdf
- Data publikacji:
- 2013
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
BINOL
atropoizomery
utleniające sprzęganie
enancjoselektywna synteza
chiralne ligandy
atropoisomers
oxidative coupling
optical resolution
enantioselective synthesis
chiral ligands - Opis:
- An invention of new catalytic strategies for stereoselective synthesis is of current interest to many laboratories worldwide . Over the past few decades a remark - able progress in the field of stereocontrolled synthesis has been achieved with chiral 1,1’-binaphthyl compounds. Optically active 1,1’-binaphthyl-2,2’-diol (BINOL) and its derivatives due to their axial dissymmetry and molecular flexibility have been widely utilized as chiral ligands and auxiliaries in stoichiometric or catalytic asymmetric reactions, such as metal-catalysed transformations and enantioselective organocatalysis. BINOL and its functionalized analogues have demonstrated remark - able chiral discrimination properties. Extensive studies on molecular recognition provided the successful results in the application of BINOL as a host for an optical resolution of racemic guests and as a chiral NMR shift reagent for the determination of chiral compounds. It has been found that the axial chirality of binaphthyl units in host molecules is crucial contribution to their stereoselctive complexation with chiral guests.
- Źródło:
-
Wiadomości Chemiczne; 2013, 67, 1-2; 55-92
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł