Temat: coagulase - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Daptomycin-resistant Staphylococcus pettenkoferi of human origin
Autorzy:: Savini, Vincenzo
Kosecka, Maja
Siegwart, Ed
Marrollo, Roberta
Polilli, Ennio
Palmieri, Dalia
Fazii, Paolo
Carretto, Edoardo
Międzobrodzki, Jacek
Bukowski, Michal
Powiązania:: https://bibliotekanauki.pl/articles/1038817.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: daptomycin resistance
coagulase-negative staphylococci
Staphylococcus pettenkoferi
Klebsiella pneumoniae
Opis:: The importance of nosocomial infections caused by coagulase-negative staphylococci is constantly growing. The threat primarily affects immunocompromised patients, the elderly and neonates, particularly after invasive surgery. The problem is fundamentally exacerbated by expanding antibacterial drug resistance. A case report is presented of an 86-year-old patient who underwent a ruptured abdominal aortic aneurysm surgery and developed septicaemia upon surgical wound infection. The causal agent was likely a carbapenem-resistant Klebsiella pneumoniae, however, daptomycin-resistant Staphylococcus pettenkoferi was identified in blood cultures in the absence of daptomycin treatment. To the authors' knowledge, the case study presented is the first published episode of daptomycin-resistant S. pettenkoferi strain.
Źródło:: Acta Biochimica Polonica; 2016, 63, 2; 297-301
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Synergistic hemolysins of coagulase-negative staphylococci (CoNS)
Autorzy:: Różalska, Małgorzata
Derczyńska, Anna
Maszewska, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/1038908.pdf
Data publikacji:: 2015
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: coagulase-negative staphylococci
CoNS
synergistic hemolysin
antimicrobial activity
cytotoxicity
Opis:: A total of 104 coagulase negative staphylococci, belonging to S. capitis, S. hominis, S. haemolyticus and S. warneri, originating from the collection of the Department of Pharmaceutical Microbiology (ZMF), Medical University of Lodz, Poland, were tested for their synergistic hemolytic activity. 83% of strains produced δ-hemolysin, however, the percentage of positive strains of S. haemolyticus, S. warneri, S. capitis and S. hominis was different - 98%, 78%, 75% and 68%, respectively. Highly pure hemolysins were obtained from culture supernatants by protein precipitation with ammonium sulphate (0-70% of saturation) and extraction by using a mixture of organic solvents. The purity and molecular mass of hemolysins was determined by TRIS/Tricine PAGE. All CoNS hemolysins were small peptides with a molar mass of about 3.5 kDa; they possessed cytotoxic activity against the line of human foreskin fibroblasts ATCC Hs27 and lysed red cells from different mammalian species, however, the highest activity was observed when guinea pig, dog and human red blood cells were used. The cytotoxic effect on fibroblasts occurred within 30 minutes. The S. cohnii ssp. urealyticus strain was used as a control. The antimicrobial activity was examined using hemolysins of S. capitis, S. hominis, S. cohnii ssp. cohnii and S. cohnii ssp. urealyticus. Hemolysins of the two S. cohnii subspecies did not demonstrate antimicrobial activity. Cytolysins of S. capitis and S. hominis had a very narrow spectrum of action; out of 37 examined strains, the growth of only Micrococcus luteus, Corynebacterium diphtheriae and Pasteurella multocida was inhibited.
Źródło:: Acta Biochimica Polonica; 2015, 62, 4; 757-764
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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