Temat: chronic diseases - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Endothelial progenitor cells participation in cardiovascular and kidney diseases: a systematic review
Autorzy:: Kiewisz, Jolanta
Kaczmarek, Monika
Pawlowska, Anna
Kmiec, Zbigniew
Stompor, Tomasz
Powiązania:: https://bibliotekanauki.pl/articles/1038766.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: endothelial progenitor cells
chronic kidney diseases
cardiovascular diseases.
Opis:: Endothelial progenitor cells (EPCs) represent a small population of blood cells (5-40 cells/mm3), with an ability to differentiate into endothelial cells that form the lining of the blood vessels and contribute to postnatal angiogenesis. Abundant evidence shows that recruitment of EPCs from the bone marrow, the monocyte/macrophage lineage and the organs facilitate the endothelial regeneration and repair. Changes in the number of EPCs were observed in both, chronic kidney and cardiovascular diseases. Thus, these cells were tested for usage in diagnosis and therapy. In this paper, we review the current knowledge on the EPC biology and contribution of these cells to the kidney and cardiovascular diseases.
Źródło:: Acta Biochimica Polonica; 2016, 63, 3; 475-482
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: The mutual cooperation of blood platelets and lymphocytes in the development of autoimmune thyroid diseases
Autorzy:: Tomczyńska, Małgorzata
Saluk-Bijak, Joanna
Powiązania:: https://bibliotekanauki.pl/articles/1038518.pdf
Data publikacji:: 2018
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: autoimmune thyroid diseases
autoantibodies
blood platelets
chronic inflammation
lymphocytes
Opis:: Autoimmune thyroid diseases include several distinct clinical entities, mainly Graves' disease and Hashimoto's thyroiditis. An incompetent immune response directed against the body's own tissues, and the production of antibodies against specific cell antigens accompanied by chronic inflammation, all occur in autoimmune thyroid diseases. The autoimmune process is induced by genetic and environmental factors that are difficult to identify and generates the development of concomitant diseases in other systems. Leukocyte activation and overproduction of inflammatory mediators, as well as improper levels of thyroid hormones, play an essential role in the chronic course of these diseases. The development of autoimmune thyroid diseases results from the impairment of the regulatory and suppressor functions of T-cells or NK cells and activation of B cells, or from the changes in the number of those cells. Many reports have shown the significant role of platelet-leukocyte interaction in inflammation. Autoantibodies react with target antigens in different kinds of cells, including blood platelets, and autoimmune processes can modulate the mutual cooperation of blood platelets and lymphocytes. The activity of blood platelets and lymphocytes is reciprocally regulated. It has been suggested that blood platelets can influence lymphocyte function by direct contact with receptors, and indirectly via soluble mediators. The interactions of platelet-immune cells (neutrophils, monocytes, lymphocyte and dendritic cells) can have a potent enhancing effect on immune cells functions.
Źródło:: Acta Biochimica Polonica; 2018, 65, 1; 17-24
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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