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Wyszukujesz frazę "Błażewicz, J." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Magnetic Polymer Nanocomposite for Medical Application
Autorzy:
Świętek, M.
Tokarz, W.
Tarasiuk, J.
Wroński, S.
Błażewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/1197651.pdf
Data publikacji:
2014-04
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
82.35.Np
87.85.-d
87.85.Rs
75.75.-c
87.85.J-
87.85.Lf
Opis:
Magnetic sponges derived from biocompatible and resorbable polymers are promising materials for medical applications. These materials have been utilised extensively in research applications for the capture of biomolecules and cells, the construction of tissue scaffolds and in regenerative medicine. The object of this study was a polymer scaffold made of polycaprolactone (PCL) containing a 10 wt% amount of nanomagnetite, manufactured in a two-step method. The porosity and morphological parameters were characterised with the use of μ-computer-aided tomography and scanning electron microscopy. Furthermore, the magnetic properties were evaluated. The obtained results confirmed high porosity and the appearance of randomly oriented pores. Moreover, evaluations of the magnetic properties, of both the magnetite nanopowder and the prepared magnetic nanocomposite, were performed. The tests verified the ferromagnetic character of the materials under investigation.
Źródło:
Acta Physica Polonica A; 2014, 125, 4; 891-894
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Applications of Comet Assay for the Evaluation of Genotoxicity and DNA Repair Efficiency in Nanomaterials Research
Autorzy:
Panek, A.
Błażewicz, M.
Frączek-Szczypta, A.
Adamczyk, J.
Wiltowska-Zuber, J.
Paluszkiewicz, C.
Powiązania:
https://bibliotekanauki.pl/articles/1030633.pdf
Data publikacji:
2018-02
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
87.53.-j
87.85.jj
87.14.gk
Opis:
The single cell gel electrophoresis method, known as comet assay, is a rapid and sensitive technique for testing novel chemicals and nanoparticles for genotoxicity, monitoring environmental contamination with genotoxins and human biomonitoring. In our studies we check the applicability of this method for the evaluation of biocompatibility of modified (MWNF) and non-modified multi-walled carbon nanotubes (MWNT) as well as potential genotoxicity of mercury(II) nitrate. The obtained results enabled us to conclude that the presence of Hg(NO₃)₂ (p<0.001) and MWNT (p<0.04) cause a significantly higher level of DNA damage in comparison to functionalised nanomaterials MWNF. It was implied that for the three investigated agents only mercury significantly enhanced genotoxic effect of X-ray exposure (p<0.001) and inhibition of radio-induced DNA damage repair. On the contrary, the presence of MWNF have no influence on cellular repair efficiencies, while incubation with MWNT causes apoptosis and consequently results in lack of attached cells. In conclusion, our results confirmed the genotoxicity of mercury and non-modified carbon nanotubes as well as the biocompatibility of modified nanotubes. Additionally, we proved the usefulness of comet method for the evaluation of genotoxicity and DNA repair under the influence of different compounds and nanomaterials.
Źródło:
Acta Physica Polonica A; 2018, 133, 2; 280-282
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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