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Wyświetlanie 1-15 z 32
Tytuł:
Sensitivity analysis of deterministic signaling pathways models
Autorzy:
Puszyński, K.
Lachor, P.
Kardyńska, M.
Śmieja, J.
Powiązania:
https://bibliotekanauki.pl/articles/201589.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
signaling pathways
sensitivity analysis
Opis:
The paper is focused on application of sensitivity methods to analysis of signaling pathway models. Two basic methods are compared: local, based on standard sensitivity functions, and global, based on Sobol indices. Firstly, a general outline of modeling of signaling pathways by means of ordinary differential equations is briefly described. Afterwards, the methods of sensitivity analysis, known from literature, are introduced and illustrated with a simple example of a dynamical system of the second order. Subsequently, the analysis of the p53/Mdm2 regulatory module, which is a key element of any pathway involving p53 protein, is presented. The results of this analysis suggest that no single method should be chosen for investigation of any signaling pathway model but several of them should be applied to answer important questions about sources of heterogeneity in cells behavior, robustness of signaling pathways and possible molecular drug targets.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 3; 471-479
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A comprehensive mathematical programming model for minimizing costs in a multiple-item reverse supply chain with sensitivity analysis
Autorzy:
Mahmoudi, H.
Fazlollahtabar, H.
Powiązania:
https://bibliotekanauki.pl/articles/407169.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
reverse supply chain
mathematical modeling
sensitivity analysis
Opis:
These instructions give you guidelines for preparing papers for IFAC conferences. A reverse supply chain is configured by a sequence of elements forming a continuous process to treat return-products until they are properly recovered or disposed. The activities in a reverse supply chain include collection, cleaning, disassembly, test and sorting, storage, transport, and recovery operations. This paper presents a mathematical programming model with the objective of minimizing the total costs of reverse supply chain including transportation, fixed opening, operation, maintenance and remanufacturing costs of centers. The proposed model considers the design of a multi-layer, multi-product reverse supply chain that consists of returning, disassembly, processing, recycling, remanufacturing, materials and distribution centers. This integer linear programming model is solved by using Lingo 9 software and the results are reported. Finally, a sensitivity analysis of the proposed model is also presented.
Źródło:
Management and Production Engineering Review; 2014, 5, 3; 42-52
2080-8208
2082-1344
Pojawia się w:
Management and Production Engineering Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of signaling pathway models based on discrete-time measurements
Autorzy:
Kardynska, M.
Smieja, J.
Powiązania:
https://bibliotekanauki.pl/articles/229721.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sensitivity analysis
signaling pathways
measurement uncertainty
discretetime measurements
Opis:
The paper is focused on sensitivity analysis of large-scale models of biological systems that describe dynamics of the so called signaling pathways. These systems are continuous in time but their models are based on discrete-time measurements. Therefore, if sensitivity analysis is used as a tool supporting model development and evaluation of its quality, it should take this fact into account. Such models are usually very complex and include many parameters difficult to estimate in an experimental way. Changes of many of those parameters have little effect on model dynamics, and therefore they are called sloppy. In contrast, other parameters, when changed, lead to substantial changes in model responses and these are called stiff parameters. While this is a well-known fact, and there are methods to discern sloppy parameters from the stiff ones, they have not been utilized, so far, to create parameter rankings and quantify the influence of single parameter changes on system time responses. These single parameter changes are particularly important in analysis of signalling pathways, because they may pinpoint parameters, associated with the processes to be targeted at the molecular level in laboratory experiments. In the paper we present a new, original method of creating parameter rankings, based on an Hessian of a cost function which describes the fit of the model to a discrete experimental data. Its application is explained with simple dynamical systems, representing two typical dynamics exhibited by the signaling pathways.
Źródło:
Archives of Control Sciences; 2017, 27, 2; 239-250
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of sandwich beams and plates accounting for variable support conditions
Autorzy:
Studziński, R.
Pozorski, Z.
Garstecki, A.
Powiązania:
https://bibliotekanauki.pl/articles/201924.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sandwich panels
sensitivity analysis
optimal design
support conditions
Opis:
The paper addresses the problems of the sensitivity analysis and optimal design of multi-span sandwich panels with a soft core and flat thin steel facings. The response functional is formulated in a general form allowing wide practical applications. Sensitivity gradients of this functional with respect to dimensional, material and support parameters are derived using adjoint variable method. These operators account for the jump of the slope of a Timoshenko beam or a Reissner plate at the position of concentrated active load or reaction, thus extending the sensitivity operators known in literature. The jump of slope is the effect of shear deformation of the core. Special attention is focussed on sensitivity and optimisation allowing for variable support position and stiffness, because local phenomena observed in supporting area of sandwich plates often initiate failure mechanisms. Introducing optimally located elastic supports allows to reduce the unfavourable influence of temperature on the state of stress. Several examples illustrate the application of derived sensitivity operators and demonstrate their exactness.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2013, 61, 1; 201-210
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of sensitivity analysis to the correction of static characteristics of a phase angle modulator
Autorzy:
Sroka, R.
Powiązania:
https://bibliotekanauki.pl/articles/220462.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
phase modulator
sensitivity analysis
static characteristics
methods of correction
Opis:
The paper presents definitions and relative measures of the system sensitivity and sensitivity of its errors. The model of a real system and model of an ideal measuring system were introduced. It allows to determine the errors of the system. The paper presents also how to use the error sensitivity analysis carried out on the models of the measuring system to the correction of the nonlinearity error of its static characteristic. The corrective function is determined as a relation between the input variable of the tested system and its chosen parameter. The use of the proposed method has been presented on the example of a phase angle modulator. The obtained results have been compared with the results of analytic calculations. The idea of a phase angle modulator is also presented.
Źródło:
Metrology and Measurement Systems; 2011, 18, 2; 249-259
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A structural optimisation viewpoint on growth phenomena
Autorzy:
Barthold, F.
Powiązania:
https://bibliotekanauki.pl/articles/201312.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
computational mechanics
structural optimisation
sensitivity analysis
configurational mechanics
growth
Opis:
Evolutionary solid bodies undergoing changes of mass, of properties, and of shapes are considered in models of growth and adaptation and similarily in structural optimisation. A fundamental separation of different growth phenomena and a subsequent parametrisation using independent design variables for the amount of substance as well as for molar mass and molar volume facilitates an efficient formulation of the design space. Thus, the effects of design variations, i.e. change of amount of substance, on the variations of the structural response, i.e. the deformation in physical space, can be clearly described. Overall, a novel treatment of growth processes based on an evolution of the amount of substance is outlined. The parallelism of variations in physical and design space are highlighted and compared with the multiplicative decomposition of the deformation gradient into a growth and an elastic part incorporating an incompatible intermediate configuration. This drawback is overcome by a compatible manifold based on material points modelling the amount of substance outside of any geometrical space.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 2; 247-252
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis and design of thermo-mechanical interfaces
Autorzy:
Dems, K.
Mroz, Z.
Powiązania:
https://bibliotekanauki.pl/articles/202338.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
multiphase structures
sensitivity analysis
optimization
heat transfer
thermo-elasticity
Opis:
An elastic structure subjected to thermal and mechanical loading with prescribed external boundary and varying internal interface is considered. The different thermal and mechanical nature of this interface is discussed, since the interface form and its properties affect strongly the structural response. The first-order sensitivities of an arbitrary thermal and mechanical behavioral functional with respect to shape and material properties of the interface are derived using the direct or adjoint approaches. Next the relevant optimality conditions are formulated. Some examples illustrate the applicability of proposed approach to control the structural response due to applied thermal and mechanical loads.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2012, 60, 2; 205-213
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity Analysis of the Estimation of the Single-Number Sound Absorption Evaluation Index DLα
Autorzy:
Batko, W.
Pawlik, P.
Wszołek, G.
Powiązania:
https://bibliotekanauki.pl/articles/176445.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sensitivity analysis
acoustic barriers
interval arithmetic
Monte Carlo method
Opis:
Acoustic barriers are assigned to the respective categories of sound absorbing properties on the basis of a single-number sound absorption evaluation index. Categories of absorbing properties play a significant role in selecting the barrier type for the given localisation. The estimation of the single-number sound absorption evaluation index is performed, among others, by means of measuring the sound absorption coefficient of the analysed acoustic barrier sample in the reverberation chamber. The sensitivity analysis of the determination of the single-number sound absorption evaluation index was performed in this work. The estimation of the input parameters uncertainty contribution to the expanded uncertainty of the sound absorption evaluation index, was done first. The Monte Carlo method and the reduction interval arithmetic were used for this aim. The relative sensitivity coefficients were determined by means of the author’s method based on the interval arithmetic. These coefficients contain information concerning the quantitative influence of the given input value on the final result.
Źródło:
Archives of Acoustics; 2017, 42, 4; 689-696
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity analysis of a new approach to photovoltaic parameters extraction based on the total least squares method
Autorzy:
Mesbahi, Oumaima
Tlemçani, Mouhaydine
Janeiro, Fernando M.
Hajjaji, Abdeloawahed
Kandoussi, Khalid
Powiązania:
https://bibliotekanauki.pl/articles/2052125.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
photovoltaic modules
parameter extraction
total least squares
MPP
sensitivity analysis
Opis:
The degradation of photovoltaic modules and their subsequent loss of performance has a serious impact on the total energy generation potential. The lack of real-time information on the output power leads to additional losses since the panels may not be operating at their optimal point. To understand the behaviour, numerically simulate the characteristics and identify the optimal operating point of a photovoltaic cell, the parameters of an equivalent electrical circuit must first be identified. The aim of this work is to develop a total least-squares based algorithm which can identify those parameters from the output voltage and current measurements, taking into consideration the uncertainties on both measured quantities. This work presents a comparative study of the Ordinary Least Squares (OLS) and Total Least Squares (TLS) approaches to the estimation of the parameters of a photovoltaic cell.
Źródło:
Metrology and Measurement Systems; 2021, 28, 4; 751-765
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Estimation of Cast Iron Substitute Thermal Capacity Using the Experimental Data
Autorzy:
Majchrzak, E.
Mendakiewicz, J.
Mochnacki, B.
Powiązania:
https://bibliotekanauki.pl/articles/353685.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
modeling of alloys solidification
numerical methods
sensitivity analysis
inverse problems
Opis:
In the paper the problem of the cast iron substitute thermal capacity estimation is discussed. This parameter appears when the macroscopic mathematical model of alloys solidification bases on the one domain method (fixed domain approach). In the case of cast iron the form of function describing the course of temperature-dependent thermal capacity is quite complex. Using the experimental data, in particular the measured cooling, heating curves at the set of points selected in the casting – mould domain the identification problem has been solved using the gradient methods. The results presented concern the gray iron 3.21% C and 1.9% Si.
Źródło:
Archives of Metallurgy and Materials; 2016, 61, 1; 307-314
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of electric field control methods for foil coils in high-voltage linear actuators
Autorzy:
Beek, T. A. van
Jansen, J. W.
Lomonova, E. A.
Powiązania:
https://bibliotekanauki.pl/articles/141173.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
electric field control methods
high voltage
linear actuators sensitivity analysis
stress grading
Opis:
This paper describes multiple electric field control methods for foil coils in high-voltage coreless linear actuators and their sensitivity to misalignment. The investigated field control methods consist of resistive, refractive, capacitive and geometrical solutions for mitigating electric stress at edges and corners of foil coils. These field control methods are evaluated using 2-D boundary element and finite element methods. A comparison is presented between the field control methods and their ability to mitigate electric stress in coreless linear actuators. Furthermore, the sensitivity to misalignment of the field control methods is investigated.
Źródło:
Archives of Electrical Engineering; 2015, 64, 4; 629-640
1427-4221
2300-2506
Pojawia się w:
Archives of Electrical Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Significance of Manufacturing Process Parameters in a Glassworks
Autorzy:
Paśko, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/175653.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
neural networks
glass industry
glass packaging
significance of variables
sensitivity analysis
machine learning
Opis:
The article presents the use of artificial neural networks (multilayer perceptrons) to examine the significance of production process parameters. The considered problem relates to the occurrence of production periods with an increased number of defective products. The research aims to determine which of the 69 parameters of the manufacturing process most affect the number of defects. Two ways of expressing the parameters significance were used: using the sensitivity analysis and exploring the weights of connections between neurons. The results were determined using both single neural networks and a set of networks. The outcome from the research is the rankings of significance of the manufacturing process parameters. The analyzed data were obtained from a glassworks producing glass packaging.
Źródło:
Advances in Manufacturing Science and Technology; 2020, 44, 2; 39-45
0137-4478
Pojawia się w:
Advances in Manufacturing Science and Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sensitivity Analysis of Acoustic Field Parameters on a Change of Boundary Conditions in a Room
Autorzy:
Suder-Dębska, K.
Czajka, I.
Czechowski, M.
Powiązania:
https://bibliotekanauki.pl/articles/177639.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sensitivity analysis
acoustic parameter
geometrical method
sound absorption coefficient
noise of power machines
Opis:
The area of environmental protection concern minimises the impact that technical objects have on the environment. Usually the most effective way of protecting the environment is to influence the source of the problem. For this reason studies are conducted to modify the construction of machines, power machines in particular, so as to minimise their impact on the environment. In the case of environmental protection from noise it is most convenient to carry out measurements in an anechoic chamber. Unfortunately, this is possible only in very limited circumstances. In all other cases measurements are performed using an engineering method or the survey method, both of which are described in the standards and by taking into account the so-called environmental corrections. The obtained results are burdened with greater error than those of measurements in an anechoic chamber. Therefore, it would seem advantageous to develop a method of obtaining similar and reliable results as those in an anechoic chamber, but in a reverberant field. The authors decided to use numerical modelling for this purpose. The main objective of this work is a comprehensive analysis of the numerical model of a laboratory designed for acoustic tests of selected power machines. The geometry of a room comprising an area of analysis is easy to design. The main difficulty in modelling the phenomena occurring in the analysed area can be the lack of knowing the boundary conditions. Therefore, the authors made an attempt to analyse the sensitivity of various acoustic parameters in a room in order to change these boundary conditions depending on the sound absorption coefficient.
Źródło:
Archives of Acoustics; 2014, 39, 3; 343-350
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Robust H∞ output feedback control of bidirectional inductive power transfer systems
Autorzy:
Swain, A.
Almakhles, D.
Neath, M. J.
Nasiri, A.
Powiązania:
https://bibliotekanauki.pl/articles/230097.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
inductive power transfer
wireless power transfer
robust control
linear matrix inequalities
sensitivity analysis
Opis:
Bidirectional Inductive power transfer (IPT) systems behave as high order resonant networks and hence are highly sensitive to changes in system parameters. Traditional PID controllers often fail to maintain satisfactory power regulation in the presence of parametric uncertainties. To overcome these problems, this paper proposes a robust controller which is designed using linear matrix inequality (LMI) techniques. The output sensitivity to parametric uncertainty is explored and a linear fractional transformation of the nominal model and its uncertainty is discussed to generate a standard configuration for μ-synthesis and LMI analysis. An H∞ controller is designed based on the structured singular value and LMI feasibility analysis with regard to uncertainties in the primary tuning capacitance, the primary and pickup inductors and the mutual inductance. Robust stability and robust performance of the system is studied through μ-synthesis and LMI feasibility analysis. Simulations and experiments are conducted to verify the power regulation performance of the proposed controller.
Źródło:
Archives of Control Sciences; 2017, 27, 1; 41-62
1230-2384
Pojawia się w:
Archives of Control Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Construction of an Expert System Based on Fuzzy Logic for Diagnosis of Analog Electronic Circuits
Autorzy:
Grzechca, D. E.
Powiązania:
https://bibliotekanauki.pl/articles/226616.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
analog circuits fault diagnosis
analog system testing
fuzzy set theory
expert system
sensitivity analysis
Opis:
The paper presents construction of the fuzzy logic system to analog circuits parametric fault diagnosis. The classical dictionary construction is replaced by fuzzy rule system. The first part refers to analog fault diagnosis, its techniques, approaches and goals. It clarifies common strategy and define differences between detecting, locating and identifying a fault in analog electronic circuit. The second part is focused on a creation of fuzzy rule expert system with use of sensitivity functions and known circuit topology. To detect, locate and identify a faulty element in a circuit the sensitivity matrix is used. The advantage of the method is its utilization in all, AC, DC and time domain. The fuzzy system, like the classical fault dictionary, can detect and locate single catastrophic faults and, on the contrary to the classical one, it also detects and locates parametric faults. Moreover, it allows identification of these faults, such that sign of the faulty parameter deviation is designated. The method has deterministic character as well as it can be applied on the verification and production stage.
Źródło:
International Journal of Electronics and Telecommunications; 2015, 61, 1; 77-82
2300-1933
Pojawia się w:
International Journal of Electronics and Telecommunications
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 32

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