Temat: Cancer - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Prognostic significance of p53 protein accumulation in cancer cells obtained from selected group of patients with sporadic colorectal cancer
Autorzy:: Paluszkiewicz, P
Karski, J.
Berbec, H.
Pawlowska-Wakowicz, B.
Cybulski, M.
Karski, M.
Paszkowska, A.
Powiązania:: https://bibliotekanauki.pl/articles/2043897.pdf
Data publikacji:: 1999
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: patient
cancer cell
monoclonal antibody
p53 protein
cancer prognosis
immunohistochemistry
sporadic colorectal cancer
accumulation
colorectal cancer
Źródło:: Journal of Applied Genetics; 1999, 40, 2; 135-144
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Nowotwory złośliwe w Polsce jako problem zdrowia publicznego
Cancer in Poland as a public health problem
Autorzy:: Wojciechowska, Urszula
Didkowska, Joanna
Koćmiel, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/418245.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: cancer
incidence
mortality
forecast
National Cancer Registry
Opis:: Malignant neoplasms are in Poland a major social problem not only in the older age groups, but they are the main cause of premature mortality (before age 65). This phenomenon is observed particularly in women - for several years cancer have been leading cause of death before age 65 (about 30% of deaths among young women and nearly 50% of deaths among middle-aged women). The projected increase in the number of cancer cases and deaths is attributable to demographic changes of the Polish population. Central Statistical Office in Poland estimates that the number of people over 65 years will increase by almost 75% by 2025. These changes translate into an increase in the number of new cases of the most common cancers in elderly (prostate, colon, lung among men and lung, breast, endometrial among women). The health phenomena taking place in the Polish population requires building a strong tool to monitor and analyze the processes involved. In case of cancer such tool is the cancer registry. In response to this need the National Cancer Registry launched a project aimed at creating a central database of cancers, establishing social baseline of conducting modern epidemiological research using information society technologies.
Źródło:: Studia Demograficzne; 2012, 161, 1; 153-166
0039-3134
Pojawia się w:: Studia Demograficzne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Age at diagnosis of cancer as predictor of mutation accurrence in families suspected of HNPCC
Autorzy:: Kurzawski, G
Debniak, T.
Kladny, J.
Lubinski, J.
Powiązania:: https://bibliotekanauki.pl/articles/2041741.pdf
Data publikacji:: 2001
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: diagnosis
mutation
age
colorectal cancer
mutational analysis
cancer
Źródło:: Journal of Applied Genetics; 2001, 42, 3; 359-366
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Uwarunkowania skłonności do palenia papierosów. Wyniki modelowania równań strukturalnych
Autorzy:: Czaderny, Krzysztof
Powiązania:: https://bibliotekanauki.pl/articles/1827684.pdf
Data publikacji:: 2017-06-02
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: lung cancer
cancer prevention
cancer control
smoking
masculinity
childhood
SEM
structural equation modeling
epidemiology
health gap
Opis:: According to the age-period-cohort projection of lung cancer incidence (ICD-10 codes C33-C34), smoking prevention will be crucial for both men and women longevity. Lung cancer remains the main cancer cause of death among males in Poland. In 2014 the number of deaths in Poland caused by lung cancer among men was more than twice as high as for women. The study is focused on identification of attitudes influencing the propensity to smoke, which is performed by structural equation modelling (SEM) based on weighted least squares means and variance adjusted (WLSMV) estimation. Good fit of the presented models is demonstrated by RMSEA, NNFI and CFI values. Reliability of scales is assessed by ordinal alpha and ordinal theta coefficients. Commitment to learning in childhood exhibits the highest standardized effect on propensity to smoke, which is an argument for youth smoking prevention. Structural equation model was estimated for men and women separately because of gender differences in smoking determinants. A strong character, individualism and self-reliance are the factors, which increase smoking propensity among males. These can be treated as features of masculinity and are not statistically important determinants of being a smoker for females. Depressive disorders, being a victim of violence as adults are statistically significant determinants of smoking among women.
Źródło:: Studia Demograficzne; 2017, 171, 1; 49-69
0039-3134
Pojawia się w:: Studia Demograficzne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Incidence of hereditary non-polyposis colorectal cancer [HNPCC] in the city of Szczecin, north-western Poland
Autorzy:: Kladny, J
Lubinski, J
Powiązania:: https://bibliotekanauki.pl/articles/2046601.pdf
Data publikacji:: 1997
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: incidence
Polska
Szczecin city
hereditary non-polyposis colorectal cancer
colorectal cancer
Opis:: The study population consisted of 140 consecutive colorectal cancer patients, inhabitants of the city of Szczecin, north-west Poland, who were histopathologically diagnosed in the period of 2 years - 1991-1992. Family history was obtained in 124 (88.6%) of patients. A definitive diagnosis of HNPCC was established if requirements of the International Collaborative Group on HNPCC (ICG- HNPCC) were met. Suspected HNPCC were recognised according to criteria described by Ponz de Leon or Mecklin or Kunitomo. HNPCC as defined by International Collaborative Group on HNPCC was identified in 2 (1.6%) families. Suspected HNPCC were recognised in 16.9%, 3.2% and 4.0% of patients if Ponz de Leon or Mecklin or Kunitomo criteria were applied, respectively. In our series in 19 of 124 cases, colorectal carcinomas were diagnosed in patients under 50 years of age. Only in one of these cases, features characteristic of HNPCC other than young age were found which suggests that in our region the frequency of somatic or germ line de novo mutations in genes predisposing to colorectal cancer may be high. Our results suggest that the frequency of HNPCC inherited from ancestors in Poland and other countries is approximately similar and this syndrome is common disease everywhere.
Źródło:: Journal of Applied Genetics; 1997, 38, 1; 103-114
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Genetic predisposition to breast and/or ovarian cancer – focus on the candidate BARD1 gene
Autorzy:: Klonowska, K.
Ratajska, M.
Wojciechowska, M.
Kozlowski, P.
Powiązania:: https://bibliotekanauki.pl/articles/80894.pdf
Data publikacji:: 2014
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: breast cancer
ovarian cancer
genetic predisposition
BRCA1 gene
structure
function
BARD1 gene
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2014, 95, 3
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Increased constitutional chromosome sensitivity to bleomycin in patients with hereditary non-polyposis colorectal cancer [HNPCC]
Autorzy:: Kladny, J
Zajaczek, S
Lubinski, J
Powiązania:: https://bibliotekanauki.pl/articles/2047245.pdf
Data publikacji:: 1996
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: chromosome sensitivity
lymphocyte
hereditary non-polyposis colorectal cancer
tumour
colorectal cancer
bleomycin
genotoxic effect
Opis:: It has been suggested that mutagen sensitivity is a constitutional factor which may be useful in identification of patients with an increased risk for the development of tumors. In this study, the chromosome sensitivity to bleomycin was measured according to Hsu in patients with hereditary non-polyposis colorectal cancer (HNPCC), sporadic colorectal cancer and in control persons with no tumor history in family. In vitro lymphocytes were exposed to bleomycin according to Hsu and chromosomal damage was quantified by scoring breaks of 100 cells. A significant difference (P < 0.01) in the mean number of breaks per cell (b/c) was found between HNPCC patients (0.59 ± 0.14; n = 12; mean age 55.4 yrs) and control individuals (0.35 ± 0.13: n = 12; mean age 55.8 yrs). In contrast, patients with sporadic colorectal cancer showed a mean b/c value of 0.43 ± 0.14 (n = 14; mean age 63.4 yrs) which was not significantly higher than that in control individuals for this group (0.42 ± 0.15; n = 14; mean age 63.1 yrs). Selenium protected lymphocytes of HNPCC patients against bleomycin activity in vitro.
Źródło:: Journal of Applied Genetics; 1996, 37, 4; 385-392
1234-1983
Pojawia się w:: Journal of Applied Genetics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Multimodal Ultrasonic Imaging for Breast Cancer Detection
Autorzy:: Camacho, J.
Medina, L.
Cruza, J. F.
Moreno, J. M.
Fritsch, C.
Powiązania:: https://bibliotekanauki.pl/articles/176695.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: ultrasound imaging
ultrasound tomography
breast cancer
Opis:: Ultrasound is used for breast cancer detection as a technique complementary to mammography, the standard screening method. Current practice is based on reflectivity images obtained with conventional instruments by an operator who positions the ultrasonic transducer by hand over the patient’s body. It is a non-ionizing radiation, pain-free and not expensive technique that provides a higher contrast than mammography to discriminate among fluid-filled cysts and solid masses, especially for dense breast tissue. However, results are quite dependent on the operator’s skills, images are difficult to reproduce, and state-of-the-art instruments have a limited resolution and contrast to show micro-calcifications and to discriminate between lesions and the surrounding tissue. In spite of their advantages, these factors have precluded the use of ultrasound for screening. This work approaches the ultrasound-based early detection of breast cancer with a different concept. A ring array with many elements to cover 360. around a hanging breast allows obtaining repeatable and operator-independent coronal slice images. Such an arrangement is well suited for multi-modal imaging that includes reflectivity, compounded, tomography, and phase coherence images for increased specificity in breast cancer detection. Preliminary work carried out with a mechanical emulation of the ring array and a standard breast phantom shows a high resolution and contrast, with an artifact-free capability provided by phase coherence processing.
Źródło:: Archives of Acoustics; 2012, 37, 3; 253-260
0137-5075
Pojawia się w:: Archives of Acoustics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: A role of ghrelin in cancerogenesis
Autorzy:: Majchrzak, K.
Szyszko, K.
Pawlowski, K.M.
Motyl, T.
Krol, M.
Powiązania:: https://bibliotekanauki.pl/articles/31726.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: ghrelin
cancerogenesis
growth hormone secretagogue receptor
cancer
mammary cancer
veterinary oncology
oncology
dog
animal disease
Opis:: Ghrelin is a 28 amino-acid multi-functional peptide hormone, which was identified as a natural ligand of the growth hormone secretagogue receptor (GHS-R). Pituitary growth hormone-releasing activity in both animals and humans has been well documented. It has various biological functions, including regulation of appetite and body weight, control of energy homeostasis, modulation of cardiovascular and gastrointestinal system and anti-inflammatory effect. However, both ghrelin and its receptor (GHS-R) are widely distributed in various tumors, which strongly implies their role in neoplastic cell growth trough autocrine/paracrine mechanism. Multiple studies have demonstrated the role of ghrelin in cancer cells proliferation, differentiation, invasiveness and apoptosis inhibition. The ghrelin axis is more complex than it was originally thought and consist of several compounds that might interact with each other and affect ghrelin activities. Here, we provide an overview of the ghrelin and its receptor role in tumor progression.
Źródło:: Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Stress and burnout among oncology nurses: review study
Autorzy:: Domagała, Przemysław Mateusz
Gaworska-Krzemińska, Aleksandra
Powiązania:: https://bibliotekanauki.pl/articles/2129219.pdf
Data publikacji:: 2018
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: psychological stress
burnout
cancer nurses
oncology nurses
Opis:: Purpose: The aim of this paper is to discuss exposure to stress and the incidence of occupational burnout among oncology nurses. Methods: To study the discussed issue, we analyzed six full-text research papers which were searchable by EBSCO and met all required criteria (words included in the abstract, English publication, size of the study group). Results: Exposure to chronic occupational stress may lead to developing burnout syndrome. Social service professionals are especially affected as they are expected to be emotionally engaged in their jobs, which particularly applies to such health care professionals as nurses, psychologists, police officers and social workers. Because of occupational burnout work efficiency may deteriorate. Oncology nurses are among the most affected nurse groups in terms of exposure to the risk of burnout. Conclusions: Oncology nurses as well as other oncology workers exhibit an increased risk and a higher grade of burnout. Psychological training sessions are available which effectively prevent and alleviate the effects of burnout.
Źródło:: Polish Psychological Bulletin; 2018, 49, 4; 482-488
0079-2993
Pojawia się w:: Polish Psychological Bulletin
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: A recently developed approach in tumor therapy using Salmonella
Autorzy:: Gharbavi, M.
Karimkhanlooei, G.
Amani, J.
Kashiazari, P.
Sharafi, A.
Powiązania:: https://bibliotekanauki.pl/articles/2097086.pdf
Data publikacji:: 2020
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: cancer therapy
combination therapy
Salmonella
tumor targeting
Opis:: There are three main approaches in cancer treatment: surgery, chemotherapy, and radiotherapy. Recently, the use of bioengineered bacteria as therapeutic agents has been shown to have some valuable properties in the treatment of cancer, which do not exist in conventional approaches. Bacteria in particular can target tumors, and they can preferentially proliferate and accumulate within tumors and inhibit the growth of cancer cells by inducing cytotoxicity. Thus, bacteria can be easily detected in tumor sites. Moreover, bacteria-derived factors exert an immunostimulatory effect. Over the past decade, Salmonella, Clostridium, and other bacterial genera have been shown to inhibit tumor growth and promote the survival rate in animal models. Clinical trials for cancer treatment with bacteria have shown improved results by combination with other therapeutic methods such as chemotherapy or radioactive agents. This review is an effort to introduce the use of healthy bacteria in tumor therapy. We specifically focus on Salmonella, which has been extensively used in tumor therapy. Therefore, in this review study, we discuss the merits, mechanisms, and attenuated strains of a combination therapy compared to other therapeutic approaches in Salmonella-mediated cancer therapy.
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2020, 101, 3; 253-267
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Nie tylko biopolityka. Historiografia „nowotworowa” w badaniach społecznej historii medycyny
Not just biopolitics. 'Cancer' historiography in the study of the social history of medicine
Autorzy:: Szpak, Ewelina
Powiązania:: https://bibliotekanauki.pl/articles/2080737.pdf
Data publikacji:: 2021
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: social history of medicine
cancer
cancer policy
biopolitics
społeczna historia medycyny
rak
polityka nowotworowa
biopolityka
Nauki Humanistyczne i Społeczne
Opis:: The aim of this article is to examine the current state of research on cancer in the field of the social history of health and illness (social history of medicine). The scope of analysis includes both Polish and foreign (English‑language) historical scientific journals and the most important monographic studies of the last three or four decades. The starting point for the following paper is the question of the origins of interest in cancer as a subject of historical research. The author indicates the main directions and dominant perspectives in the historical discourse of cancer, and through such a perspective, simultaneously tries to see to what extent research approaches on cancer history differ or converge in the approaches of different countries. The last aspect of the history of cancer, briefly outlined, touches upon the extent to which historical, anthropological and sociological as well as medical (history of medicine) research are intertwined and mutually inspiring or complementary.
Źródło:: Historyka studia metodologiczne; 2021, 51; 453-479
0073-277X
Pojawia się w:: Historyka studia metodologiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Suppression of negative affect in cancer patients. Trauma and defensiveness of self-esteem as predictors of depression and anxiety
Autorzy:: Fila-Jankowska, Aleksandra
Szawińska, Agata
Powiązania:: https://bibliotekanauki.pl/articles/430663.pdf
Data publikacji:: 2016-09-01
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: cancer
anxiety
depression
stressful events
self-esteem defensiveness
Opis:: The results of the work show that the relatively small differences in declared, negative emotional states (such as depression or anxiety) between people suffering and not suffering from cancer can be explained by the suppression of negative affect in the former. It was assumed that the suppression is related to a compensation of an automatic, affective self-assessment - i.e. implicit self-esteem, lower in cancer patients. The results confirmed that the connection of cancer and depression (similarly cancer and anxiety) became significantly stronger while the self-esteem defensiveness and past stress are statistically controlled.
Źródło:: Polish Psychological Bulletin; 2016, 47, 3; 318-326
0079-2993
Pojawia się w:: Polish Psychological Bulletin
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Characterisation of genome-wide structural aberrations in canine mammary tumours using single nucleotide polymorphism (SNP) genotyping assay
Autorzy:: Surdyka, M.
Gurgul, A.
Slaska, B.
Pawlina, K.
Szmatola, T.
Bugno-Poniewierska, M.
Smiech, A.
Kasperek, K.
Powiązania:: https://bibliotekanauki.pl/articles/2087566.pdf
Data publikacji:: 2019
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: dog
cancer
mammary tumour
structural aberration
CNV
LOH
Źródło:: Polish Journal of Veterinary Sciences; 2019, 1; 133-141
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Skin Lesion Analysis Toward Melanoma Detection Using Deep Learning Techniques
Autorzy:: Sherif, Fatma
Mohamed, Wael A.
Mohra, A.S.
Powiązania:: https://bibliotekanauki.pl/articles/226719.pdf
Data publikacji:: 2019
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: melanoma
skin cancer
convolutional neural network
deep learning
Opis:: In the last few years, a great attention was paid to the deep learning Techniques used for image analysis because of their ability to use machine learning techniques to transform input data into high level presentation. For the sake of accurate diagnosis, the medical field has a steadily growing interest in such technology especially in the diagnosis of melanoma. These deep learning networks work through making coarse segmentation, conventional filters and pooling layers. However, this segmentation of the skin lesions results in image of lower resolution than the original skin image. In this paper, we present deep learning based approaches to solve the problems in skin lesion analysis using a dermoscopic image containing skin tumor. The proposed models are trained and evaluated on standard benchmark datasets from the International Skin Imaging Collaboration (ISIC) 2018 Challenge. The proposed method achieves an accuracy of 96.67% for the validation set. The experimental tests carried out on a clinical dataset show that the classification performance using deep learning-based features performs better than the state-of-the-art techniques.
Źródło:: International Journal of Electronics and Telecommunications; 2019, 65, 4; 597-602
2300-1933
Pojawia się w:: International Journal of Electronics and Telecommunications
Dostawca treści:: Biblioteka Nauki

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