Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "A2" wg kryterium: Temat

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-12 z 12
    Tytuł:
    Linkage and interdependence of A2MD1 and A2ME2 alpha2-macroglobulin genes in cattle
    Autorzy:
    Wegrzyn, J
    Skiba, E
    Krzyscin, P
    Powiązania:
    https://bibliotekanauki.pl/articles/2047144.pdf
    Data publikacji:
    1997
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    antigen marker
    gene
    animal production
    alpha2-macroglobulin
    cattle
    antigenic determinant
    protein
    marker
    A2MD1 gene
    A2ME2 gene
    Opis:
    The transmission of previously described genes A2MD1 and A2ME2 that determine antigenic markers of alpha₂-macroglobulins A₂mD1 and А₂mЕ2 in cattle was studied. The starting point for the analyses was the lack of individuals negative for both markers in the population of 3551 Black-and-White, Red-and-White, Polish Red and Simmental cattle and interbreed crosses. Controlling of these specificities by allelic genes or genes from closely linked loci was considered. To support or reject this hypothesis, the independence test 2 x 2 and analysis of segregation of A₂mD1 and А₂mЕ2 in the offsprings of all phenotypic matings found and of selected matings in which genotypes of sires were determined, were used. It was found that the observed segregation of antigenic markers in the offsprings rules out the possibility that they are determined by allelic genes. The results obtained show that markers A₂mD1 and А₂mЕ2 are controlled by the genes A2MD1 and A2ME2 from closely linked loci. Moreover it seems that only those haplotypes are transmitted in which both genes - A2MD1 and A2ME2, or one of them - A2MD1 or A2ME2, are present. No haplotypc would then be transmitted (would occur?) in which both genes are in the recessive form. recessive form.
    Źródło:
    Journal of Applied Genetics; 1997, 38, 2; 187-193
    1234-1983
    Pojawia się w:
    Journal of Applied Genetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular studies in osteogenesis imperfecta [OI] II. Evaluation of intragenic polymorphic sites in COL1A1 and COL1A2 loci
    Autorzy:
    Kostyk, E
    Sucharski, P.
    Pietrzyk, J.J.
    Kruczek, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044212.pdf
    Data publikacji:
    1998
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    intragenic polymorphic site
    polymorphism
    haplotype
    DNA isolation
    COL1A1 gene
    electrophoresis
    collagen
    COL1A2 gene
    molecular marker
    osteogenesis imperfecta
    Opis:
    The goal of the study was to evaluate intragenic polymorphic sites in COL1A1 and COL1A2 loci. For COL1A1 the following intragenic markers were used: PCR-RFLP (COL1A1), G/A polymorphism in exon 45 of COL1A1 and C/T polymorphism in +88 position of COL1A1 non-translatable 3’ end. For COL1A2 PCR-VNTR was analyzed. 17 families were examined (6 of the "simplex" type and 11 of the "multiple" type). In 8 out of 11 "multiplex" families the segregation of the markers revealed correlation with OI, whereas the other 3 were non-informative. The method was not useful in "simplex" families.
    Źródło:
    Journal of Applied Genetics; 1998, 39, 4; 349-365
    1234-1983
    Pojawia się w:
    Journal of Applied Genetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular docking and pharmacokinetic prediction of phytochemicals from Syzygium cumini in interaction with penicillin-binding protein 2a and erythromycin ribosomal methylase of Staphylococcus aureus
    Autorzy:
    Shidiki, A.
    Vyas, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2096259.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    methicillin-resistant S. aureus
    penicillin-binding protein 2a
    erythromycin ribosomal methylase
    Opis:
    Background. MRSA and MLSB resistant S. aureus are known as important pathogens, which are responsible for many cases of both hospital and community-acquired infections worldwide. Studying drug discovery from plant sources is regarded as an important prevention strategy regarding these types of infections. Material and methods. Agar well diffusion method was performed for antimicrobial evaluation, LCMS technique used for identification of different compounds, molecular docking performed by application of iGEMDOCK for PBP2a and ERM to plant compounds, and its pharmacokinetic evaluation of ADMET through use of AdmetSAR. Results. Water extract was the most effective against resistant strains of Staphylococcus aureus. Twenty compounds belonging to phenols, flavonoids, organic acids, terpenoids groups were reported. Eighteen plant compounds passed in Lipinski's rule of five. iGEMDOCK revealed diferulic acid has the least binding energy -102.37 kcal/mole to penicillin-binding protein 2a and taxifolin has the least binding energy of -103.12 kcal/mole to erythromycin ribosomal methylase in comparison to control linezolid. These compounds raise the potential for developing potent inhibitors of penicillin-binding protein 2a and erythromycin ribosomal methylase for drug development. ADMET properties revealed that eighteen studied compounds were found in category III and IV with non-toxic properties except two butin and taxifolin found in category II with toxic properties. Conclusions. It can be concluded that diferulic acid and taxifolin compounds provide the best inhibitor effect to PBP2a and ERM protein for inhibition of MRSA and MLSB resistant strains of S. aureus through the application of molecular docking, leading to a lead drug candidate for the treatment of diseases.
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 5-18
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular studies in osteogenesis imperfecta [OI] III. cDNA of COL1A1 and COL1A2 analysis using the BESS-T-Scan technique
    Autorzy:
    Sucharski, P
    Sanak, M.
    Kostyk, E.
    Pietrzyk, J.J.
    Kruczek, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044221.pdf
    Data publikacji:
    1998
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    COL1A1 gene
    electrophoresis
    COL1A2 gene
    collagen production
    man
    RNA isolation
    mutation
    BESS-T-Scan technique
    molecular diagnosis
    DNA
    osteogenesis imperfecta
    cDNA synthesis
    fibroblast culture
    Opis:
    A BESS-T-Scan analysis of cDNA COL1A1 and COL1A2 obtained by RT-PCR derived from five patients with sporadic forms of ostegenesis imperfecta was performed. The study was done in four patients with type I and one patient with type III OI. The analysis revealed the presence of structural changes in two regions of cDNA COL1A1 in two patients. No quantitative changes referring to COL1A2 gene were noted in any patient. The above analysis was the first application of the BESS-T-Scan technique in a molecular diagnosis of OI. The applied method seems to be useful and fulfil the basic criteria of the screening method to detect and locate mutations.
    Źródło:
    Journal of Applied Genetics; 1998, 39, 4; 367-373
    1234-1983
    Pojawia się w:
    Journal of Applied Genetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Treatment of wastewater from service areas at motorways
    Oczyszczanie ścieków z miejsc obsługi podróżnych przy autostradzie
    Autorzy:
    Makowska, M.
    Mazurkiewicz, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/205279.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    motorway service areas
    local treatment plants
    biofilters
    wastewater treatment
    facilities at transport routes
    miejsca obsługi podróżnych
    MOP
    natężenie ruchu
    autostrada A2
    oczyszczalnie lokalne
    biofiltr
    jakość ścieków
    Opis:
    This paper deals with wastewater treatment systems placed in motorway service areas (MSAs). In the years 2008-2009 eight of such facilities installed on the stretch of the A2 motorway between Poznań and Nowy Tomyśl were examined and analyzed. The system consists of a septic tank, a submerged aerated biofilter and an outflow filter. The volume of traffic on the highway was analyzed, the amount of water use was measured and peak factors were calculated. On this basis it was concluded that the inflows to the wastewater treatment systems in many cases exceeded the nominal design values. Based on the analysis of effluent quality it was found that the effects of plant operation in large part did not meet the requirements. It was found that the bioreactor aeration system and the design of the suspension separator (outflow filter) should be modified. One of the solutions was to use the soil-reed bed for wastewater treatment. The treatment of wastewater from the MSAs is a task that must take into account the unusual character of these facilities and the atypical quality of the effluent.
    Praca dotyczy systemów oczyszczania ścieków w Miejscach Obsługi Podróżnych (MOP) przy autostradach. Badano i analizowano 8 instalacji zamontowanych w MOP-ach przy autostradzie A2 między Poznaniem a Nowym Tomyślem. Systemy składają się z osadnika gnilnego, zanurzonego, napowietrzanego złoża biologicznego i filtra odpływowego. Analizowano natężenie ruchu na autostradzie, ilość zużywanej wody oraz jakość ścieków na wlocie i wylocie z bioreaktora. Na tej podstawie stwierdzono, że wielkość oczyszczalnie nie jest adekwatna do ilości i jakości dopływających ścieków. Stwierdzono, że jakość odpływu jest niezadowalająca oraz zaproponowano zmiany konstrukcyjne i technologiczne.
    Źródło:
    Archives of Environmental Protection; 2016, 42, 4; 80-89
    2083-4772
    2083-4810
    Pojawia się w:
    Archives of Environmental Protection
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Interplay of two PP2A B subunits in high light acclimation
    Autorzy:
    Konert, G.
    Trotta, A.
    Rahikainen, M.
    Kangasjarvi, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/80957.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    reactive oxygen species
    homeostasis
    alternative oxidase
    proteomic analysis
    signalling pathway
    PP2A phosphatase
    B subunit
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    PP2A phosphatase interacts with CPK kinase and regulates pathogenesis responses triggered by intracellular ROS signals
    Autorzy:
    Kangasjarvi, S.
    Denessiouk, K.
    Trotta, A.
    Konert, G.
    Rahikainen, M.
    Li, S.
    Mhamdi, A.
    Noctor, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/80995.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    protein phosphatase 2A
    calcium-dependent protein kinase
    reactive oxygen species
    organelle
    protein kinase
    plant immunity
    Arabidopsis
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Emotional expression in a foreign language. What factors influence the choice of a non-native language while expressing emotions
    Autorzy:
    Ożańska-Ponikwia, Katarzyna
    Powiązania:
    https://bibliotekanauki.pl/articles/577078.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bilingualism
    expression of emotion in a foreign language
    L2 use
    sociocultural competence
    Opis:
    The present contribution is concerned with the expression of emotions in a foreign language. It seeks to investigate what factors among gender, educational level, exposure to a foreign language and culture, L2 use, length of stay in a foreign country, or self-perceived L2 proficiency might influence the choice of a foreign language for emotional expression. The statistical analysis of 102 Polish-English bilinguals and Polish L2 users of English responses to an online questionnaire measuring expression of emotions in a foreign language reviled that the L2 use, self-perceived L2 proficiency and frequent contact with the L2 were linked to the expression of emotions in a foreign language. The results of this study show the complexity of the relationship between language, culture and emotions, suggesting that the exposure to a foreign language and its culture might be the key factor facilitating the choice of a non-native language while talking about emotions.
    Źródło:
    Linguistica Silesiana; 2012, 33; 203-219
    0208-4228
    Pojawia się w:
    Linguistica Silesiana
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fabrication of Mo-Si-B Intermetallic Compound Powders Under Different Heat Treatment Conditions
    Autorzy:
    Park, J. H.
    Lee, S.
    Kim, D.
    Kim, Y.
    Yang, S. H.
    Lee, S. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/353369.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Mo-Si-B alloys
    intermetallic compounds
    reitveld refinement
    T2 phase
    A15 phase
    Opis:
    In this research, we investigated the effects of reduction atmospheres on the creation of the Mo-Si-B intermetallic compounds (IMC) during the heat treatments. For outstanding anti-oxidation and elevated mechanical strength at the ultrahigh temperature, we fabricated the uniformly dispersed IMC powders such as Mo5SiB2 (T2) and Mo3Si (A15) phases using the two steps of chemical reactions. Especially, in the second procedure, we studied the influence of the atmospheres (e.g. vacuum, argon, and hydrogen) on the synthesis of IMCs during the reduction. Furthermore, the newly produced IMCs were observed by SEM, XRD, and EDS to identify the phase of the compounds. We also calculated an amount of IMCs in the reduced powders depending on the atmosphere using the Reitveld refinement method. Consequently, it is found that hydrogen atmosphere was suitable for fabrication of IMC without other IMC phases.
    Źródło:
    Archives of Metallurgy and Materials; 2018, 63, 3; 1509-1512
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Effect of Cooling Rate after Homogenization on the Microstructure and Properties of 2017a Alloy Billets for Extrusion with Solution Heat Treatment on the Press
    Autorzy:
    Woźnicki, A.
    Leśniak, D.
    Włoch, G.
    Pałka, P.
    Leszczyńska-Madej, B.
    Wojtyna, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/355500.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    2017A alloy
    cooling rate after homogenization
    θ (Al2Cu) phase particles precipitation
    Opis:
    The influence of cooling rate after homogenization on the 2017A alloy microstructure was analysed. The capability of the θ (Al2Cu) particles, precipitated during various homogenization coolings, for rapid dissolution was estimated. For this purpose, the DSC test was used to determine the effect of the cooling rate after homogenization on the course of melting during a rapid heating. Moreover, the samples after solution heat treatment (with short time annealing) and ageing, were subjected to the microstructure investigations and the microhardness of grains interiors measurements. It was found that cooling after homogenization at 160 °C/h is sufficient for precipitation of fine θ phase particles, which dissolve during the subsequent rapid heating. The cooling at 40 °C/h, causes the precipitation of θ phase in the form of large particles, incapable of further fast dissolution.
    Źródło:
    Archives of Metallurgy and Materials; 2016, 61, 3; 1663-1670
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sequential fluorescent staining with CMA and DAPI for somatic chromosome identification in cucumber [Cucumis sativus L.]
    Autorzy:
    Plader, W
    Hoshi, Y.
    Malepszy, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/2044260.pdf
    Data publikacji:
    1998
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    heterochromatin
    4',6-diamidino-2-phenylindole
    euchromatin segment
    hybridization
    chromosome identification
    mitotic chromosome
    prometaphase chromosome
    somatic cell
    cucumber
    DNA
    chromomycin A3
    Cucumis sativus
    Opis:
    Each of the seven chromosomes in cucumber (Cucumis sativus L.) was identified using sequential staining with Chromomycin A₃ (CMA) and 4-6-diamidino-2-phenylindole (DAPI) as DNA base-specific fluorescent dyes. The present method using enzymatic digestion produced a high level of well-spread early-metaphase chromosome complements. After CMA and DAPI staining, reproducible fluorescence bands were obtained in mitotic prometaphase chromosomes. The CMA staining method made it possible to characterize whole chromosomes from prometaphase to mid-metaphase. Chromosome 1 had the largest and widest CMA-positive (CMA⁺) band from the proximal region to the interstitial region on the long arm in prometaphase. A large gap separating of the short arm from the long arm was always observed in chromosome 2 during prometaphase. The banding pattern of the short arm was similar to that of the long arm in chromosome 2. Chromosomes 1 and 2 in early metaphase had sharp and large CMA-positive and DAPI-negative (CMA⁺DAPI⁻) bands at the pericentromeric regions. In early metaphase, chromosome 3 was characterized by having a narrow CMA⁺DAPI⁻ band on the pericentromeric region of the short arm. Chromosomes 4 and 5 showed similar chromosome length and had a large CMA⁺ band at the distal region of the long arm. Chromosome 4 did not show any clear band in the short arm, while chromosome 5 showed a telomeric CMA⁺ band at the short arm and a clear CMA⁺DAPI⁻ band at the pericentromeric region. Chromosome 6 had a CMA⁺ band at the distal region and a weak CMA⁺ band at the proximal region in each of the arms. Chromosome 7 had an evident CMA⁺ band in the long arm and a CMA⁺ DAPI⁻ band in the pericentromeric region.
    Źródło:
    Journal of Applied Genetics; 1998, 39, 3; 249-258
    1234-1983
    Pojawia się w:
    Journal of Applied Genetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hazardous Compounds in Urban Pm in the Central Part of Upper Silesia (Poland) in Winter
    Niebezpieczne związki w miejskim pyle zawieszonym w centralnej części Górnego Śląska w zimie
    Autorzy:
    Rogula-Kozłowska, W.
    Kozielska, B.
    Klejnowski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/204935.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    pył zawieszony
    pył PM2,5
    pył PM1
    metale ciężkie
    WWA
    wielopierścieniowe węglowodory aromatyczne
    związki rakotwórcze
    jakość powietrza
    Zabrze
    PM1
    PM2,5
    heavy metals
    PAH
    benzo(a)pyrene
    carcinogenicity
    hazardous compounds
    toxicity equivalency factor
    BEQ
    Opis:
    Thirteen fractions of ambient dust were investigated in Zabrze, a typical urban area in the central part of Upper Silesia (Poland), during a heating season. Fifteen PAH and Cr, Mn, Co, Ni, As, Se, Cd, Pb contents of each fraction were determined. The dust was sampled with use of a cascade impactor and chemically analyzed with an energy dispersive X-ray fl uorescence spectrometer (PANalytical Epsilon 5) and a gas chromatograph with a fl ame ionisation detector (Perkin Elmer Clarus 500). The concentrations of PM1 and the PM1-related PAH and elements were much higher than the ones of the coarse dust (PM2.5-10) and the substances contained in it. The concentrations of total PAH and carcinogenic PAH were very high (the concentrations of PM1-, PM2.5-, and PM10-related BaP were 16.08, 19.19, 19.32 ng m-3, respectively). The municipal emission, resulted mainly from hard coal combustion processes, appeared to be the main factor affecting the air quality in Zabrze in winter.
    Próbki trzynastu frakcji pyłu zawieszonego były pobierane w Zabrzu w okresie grzewczym (centralna część Górnego Śląska, Polska). Punkt poboru jest charakterystyczny dla obszaru miejskiego. Zbadano zawartość 15 WWA oraz Cr, Mn, Co, Ni, As, Se, Cd, Pb w każdej frakcji pyłu. Do poboru pyłu zastosowano impaktor kaskadowy, a do analizy chemicznej – spektrometr fl uorescencji rentgenowskiej z dyspersją energii (PANalytical Epsilon 5) oraz chromatograf gazowy z detektorem płomieniowo-jonizacyjnym (Perkin Elmer Clarus 500). Zarówno stężenia pyłu PM1 jak i stężenia związanych z nim WWA i pierwiastków były znacznie wyższe niż stężenia pyłu grubego (PM2.5-10) i związanych z nim substancji. Stężenia sumy WWA, a w szczególności kancerogennych związków tej grupy były bardzo wysokie (np. stężenia dla BaP związanego z PM1- i PM2.5- oraz PM10- wynosiły odpowiednio: 16.08, 19.19, 19.32 ng m-3). Na podstawie uzyskanych wyników badań dla ww. zanieczyszczeń stwierdzono, że za stan jakości powietrza w Zabrzu, w zimie, odpowiedzialna jest emisja komunalna – stacjonarne źródła spalania, głównie spalanie węgla.
    Źródło:
    Archives of Environmental Protection; 2013, 39, 1; 53-65
    2083-4772
    2083-4810
    Pojawia się w:
    Archives of Environmental Protection
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-12 z 12

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies