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    Wyświetlanie 1-15 z 15
    Tytuł:
    Comparison of analgesia provided by lidocaine or morphine delivered epidurally in rabbits undergoing hindlimb orthopedic surgery
    Autorzy:
    Antończyk, A.
    Liszka, B.
    Skrzypczak, P.
    Kiełbowicz, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087571.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    epidural anesthesia
    intraoperative pain
    lidocaine
    morphine
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 1; 31-35
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Assessments of treatment of Osteochondrosis dissecans (OCD) of shoulder joint in dogs - the result of two years of experience
    Autorzy:
    Biezynski, J.
    Skrzypczak, P.
    Piatek, A.
    Kosciolek, N.
    Drozdzynska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31872.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Osteochondrosis is a common and clinically important joint disorder that occurs in human and many species of animals such as pigs, horses and dogs. The aim of this article is to present the results of conservative and surgical treatment of Osteochondrosis dissecans (OCD) and to compare the recovery time in relation to race, age and extent of cartilage damage. The study was performed on 36 dogs of both sexes, aged from 4 to 24 months, weighing 12-70 kg, of different breeds (predisposed and non-specific for this disease). All patients underwent clinical, orthopedic and radiological examination through which the location of OCD changes in the shoulder joint and the degree of this problem were established. Based on the examinations the patients were qualified for particular treatment procedures. Control tests were performed after 14, 30 and 60 days, which allowed for a precise evaluation of the progress of therapy. Achieved results indicate that dogs age and the lesions extent in the shoulder joint have an impact on the outcome of treatment. Studies showed that the best therapeutic effects were obtained in dogs aged 6-10 months, which underwent surgery. The study proved that the early diagnosis of OCD strongly influence the recovery rate and may inhibit the development of degenerative changes in the joint (DJD).
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of serum cytokine levels in recurrent airway obstruction
    Autorzy:
    Niedzwiedz, A.
    Borowicz, H.
    Kubiak, K.
    Nicpon, J.
    Skrzypczak, P.
    Jaworski, Z.
    Cegielski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31728.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Recurrent airway obstruction (RAO) represents a serious health problem and is traditionally classified as an allergic disease, where contact with an antigen can induce clinical airway inflammation, bronchial hyper-responsiveness and reversible airway obstruction. Previous studies have demonstrated the presence of the Th2 response in the lungs of human patients with asthma and horses with heaves. These cells are involved in the production of cytokines which regulate the synthesis of immunoglobulins. 40 horses were evaluated: 30 horses with RAO and 10 healthy animals. The expression levels of interferon-alpha 1 (IFN-α1), interferon-gamma (IFN-γ), interleukin-1β, (IL-1β), IL-2, IL-4, IL-13 and tumor necrosis factor alpha (TNF-α) were measured in the serum obtained from control and RAO-susceptible horses during crisis. In all the patients, serum cytokine levels were detected. Serum median IL-13 and IFN-γ levels were significantly higher in RAO-affected horses than in the healthy group (p < 0.001). The serum median IFN-α1, IL-1β, IL-2, IL-4, and TNF-α levels were similar in both groups. These results indicate a low variability of the levels of cytokines and a high frequency of their detection in serum samples from horses with RAO. Immune mechanisms involved in equine RAO are more complex than those defined by a simple Th1/Th2 dichotomy.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The experimental osteoporosis in sheep - clinical approach
    Autorzy:
    Kielbowicz, Z.
    Piatek, A.
    Biezynski, J.
    Skrzypczak, P.
    Kuropka, P.
    Kuryszko, J.
    Nikodem, A.
    Kafarski, P.
    Pezowicz, C.
    Powiązania:
    https://bibliotekanauki.pl/articles/30991.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The implementation of new methods of oseoporotic therapy requires tests on an animal model. One of the best is the sheep, whose numerous advantages over other models are described in the literature. The aim of this study was induction of osteoporosis using steroids and ovariorectomy methods in sheep and description of the change in parameters with regard to healthy sheep. The study was performed on female „merino” breed sheep divided into three groups: Negative control (NC) healthy animals, positive control (PC) ovariorectomised animals and steroid group (SC) where methylprednisolone was implemented. Blood tests, diagnostic arthroscopy, quantitative computed tomography and X-Ray micro-tomography of bone were carried out. Blood tests revealed a decreased level of estrogens, progesterone and increased parathormone and cortisol levels in the SC group. A decrease in bone turnover markers and an increase in bone resorption markers in all groups were also noted. Diagnostic arthroscopy revealed osteoarthrosis in PC and SC groups. Radiological density tests showed a slight decrease in PC and NC groups whereas there was more than a triple decrease in SC. Results obtained from microCT showed quickly developing osteoporosis in the SC group, which is reflected in numerous parameters analysed in this study. The best effects for osteoporosis induction were obtained using ovariorectomised sheep with methylprednisolone injections.
    Źródło:
    Polish Journal of Veterinary Sciences; 2015, 18, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Experimental osteoporosis in sheep - mechanical and histological approach
    Autorzy:
    Kielbowicz, Z.
    Piatek, A.
    Kuropka, P.
    Mytnik, E.
    Nikodem, A.
    Biezynski, J.
    Skrzypczak, P.
    Pezowicz, C.
    Kuryszko, J.
    Reichert, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/31160.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The implementation of new methods of osteoporotic therapy requires tests on animal model. The use of sheep as model has numerous advantages over other animals. The aim of this study was to describe the change in parameters in sheep with osteoporosis induced using steroids and ovariorectomy methods as opposed to the parameters in healthy sheep. The study was performed on female „merinos” breed sheep divided into the three groups: negative control (NC) – healthy animals, positive control (PC) – ovariorectomized animals and steroid control group (SC) – in which methylprednisolone was administered. This paper presents histological and ultrastructural examination with mechanical comparative tests for force/strength values as well as indentation tests of joint cartilage. The obtained results confirm the loss of bone mass associated with mineral composition content in bones, which has an influence on bone strength.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of short-term rapid ventricular pacing followed by pacing interruption on arterial blood pressure in healthy pigs and pigs with tachycardiomyopathy
    Autorzy:
    Skrzypczak, P.
    Zysko, D.
    Paslawska, U.
    Noszczyk-Nowak, A.
    Janiszewski, A.
    Gajek, J.
    Nicpon, J.
    Kiczak, L.
    Bania, J.
    Zacharski, M.
    Tomaszek, A.
    Jankowska, E.A.
    Ponikowski, P.
    Witkiewicz, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/32380.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Ventricular tachycardia may lead to haemodynamic deterioration and, in the case of long term persistence, is associated with the development of tachycardiomyopathy. The effect of ventricular tachycardia on haemodynamics in individuals with tachycardiomyopathy, but being in sinus rhythm has not been studied. Rapid ventricular pacing is a model of ventricular tachycardia. The aim of this study was to determine the effect of rapid ventricular pacing on blood pressure in healthy animals and those with tachycardiomyopathy. A total of 66 animals were studied: 32 in the control group and 34 in the study group. The results of two groups of examinations were compared: the first performed in healthy animals (133 examinations) and the second performed in animals paced for at least one month (77 examinations). Blood pressure measurements were taken during chronic pacing - 20 min after onset of general anaesthesia, in baseline conditions (20 min after pacing cessation or 20 min after onset of general anaesthesia in healthy animals) and immediately after short-term rapid pacing. In baseline conditions significantly higher systolic and diastolic blood pressure was found in healthy animals than in those with tachycardiomyopathy. During an event of rapid ventricular pacing, a significant decrease in systolic and diastolic blood pressure was found in both groups of animals. In the group of chronically paced animals the blood pressure was lower just after restarting ventricular pacing than during chronic pacing. Cardiovascular adaptation to ventricular tachycardia develops with the length of its duration. Relapse of ventricular tachycardia leads to a blood pressure decrease more pronounced than during chronic ventricular pacing.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gamma-secretase complex in plant cells
    Autorzy:
    Skrzypczak, T.
    Smolarkiewicz, M.
    Wojtaszek, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/80341.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    conference
    gamma-secretase
    beta-amyloid peptide
    beta-amyloid precursor protein
    proteolysis
    calcium homeostasis
    apoptosis
    synapse
    intercellular junction
    Arabidopsis
    plant cell
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Influence of Riser Shape on Feeding Effectiveness of Solidifying Casting
    Autorzy:
    Sowa, L.
    Skrzypczak, T.
    Kwiatoń, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/383146.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    solidification process
    castings defects
    numerical simulation
    liquid metal flow
    proces krzepnięcia
    wady odlewów
    symulacja numeryczna
    przepływ ciekłego metalu
    Opis:
    The mathematical model and numerical simulations of the solidification of a cylindrical shaped casting, which take into account the process of filling the mould cavity by liquid metal and feeding the casting through the riser during its solidification, are presented in the paper. Mutual dependence of thermal and flow phenomena were taken into account because have an essential influence on solidification process. The effect of the riser shape on the effectiveness of feeding of the solidifying casting was determined. In order to obtain the casting without shrinkage defects, an appropriate selection of riser shape was made, which is important for foundry practice. Numerical calculations of the solidification process of system consisting of the casting and the conical or cylindrical riser were carried out. The velocity fields have been obtained from the solution of momentum equations and continuity equation, while temperature fields from solving the equation of heat conductivity containing the convection term. Changes in thermo-physical parameters as a function of temperature were considered. The finite element method (FEM) was used to solve the problem.
    Źródło:
    Archives of Foundry Engineering; 2019, 4; 91-94
    1897-3310
    2299-2944
    Pojawia się w:
    Archives of Foundry Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Effect of Metal Pouring Conditions on the Formation of Defects in the Casting
    Autorzy:
    Sowa, L.
    Skrzypczak, T.
    Kwiatoń, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/946863.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    castings defects
    solidification process
    numerical modelling
    molten metal flow
    wady odlewów
    proces krzepnięcia
    modelowanie numeryczne
    metal ciekły
    Opis:
    The mathematical model and numerical simulations of the solidification of a cylindrical casting, which take into account the process of the mould cavity filling by liquid metal and the feeding of the casting through the conical riser during its solidification, are proposed in the paper. The interdependence of thermal and flow phenomena were taken into account because they have an essential influence on solidification process. The effect of the pouring temperature and pouring velocity of the metal on the solidification kinetics of the casting was determined. In order to obtain the casting without shrinkage defects, an appropriate selection of these parameters was tried, which is important for foundry practice. The velocity fields have been obtained from the solution of Navier-Stokes equations and continuity equation, while temperature fields from solving the equation of heat conductivity containing the convection term. In the solidification modelling the changes in thermo-physical parameters as a function of temperature were considered. The finite element method (FEM) was used to solve the problem.
    Źródło:
    Archives of Foundry Engineering; 2020, 20, 2; 31-36
    1897-3310
    2299-2944
    Pojawia się w:
    Archives of Foundry Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of Temperature and Velocity Fields During Filling of Continuous Casting Mould
    Autorzy:
    Sowa, L.
    Skrzypczak, T.
    Kwiatoń, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/379679.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    solidification process
    continuous casting
    numerical simulation
    molten metal flow
    krzepnięcie
    odlewanie
    symulacja numeryczna
    Opis:
    In this paper, the mathematical model and numerical simulations of the molten steel flow by the submerged entry nozzle and the filling process of the continuous casting mould cavity are presented. In the mathematical model, the temperature fields were obtained by solving the energy equation, while the velocity fields were calculated by solving the momentum equations and the continuity equation. These equations contain the turbulent viscosity which is found by solving two additional transport equations for the turbulent kinetic energy and its rate of dissipation. In the numerical simulations, coupling of the thermal and fluid flow phenomena by changes in the thermophysical parameters of alloy depending on the temperature has been taken into consideration. This problem (2D) was solved by using the finite element method. Numerical simulations of filling the continuous casting mould cavity were performed for two variants of liquid metal pouring. The effect of the cases of pouring the continuous casting mould on the velocity fields and the solid phase growth kinetics in the process of filling the continuous casting mould was evaluated as these magnitudes have an influence on the high quality of the continuous cast steel slab.
    Źródło:
    Archives of Foundry Engineering; 2018, 18, 1; 115-118
    1897-3310
    2299-2944
    Pojawia się w:
    Archives of Foundry Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Numerical Evaluation of the Impact of Riser Geometry on The Shrinkage Defects Formation in the Solidifying Castin
    Autorzy:
    Sowa, L.
    Skrzypczak, T.
    Kwiatoń, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/2048812.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    numerical simulations
    solidification
    casting defects
    FEM
    Opis:
    The work concerns of modeling the process of manufacturing machine parts by casting method. Making a casting without internal defects is a difficult task and usually requires numerous computer simulations and their experimental verification at the prototyping stage. Numerical simulations are then of priority importance in determining the appropriate parameters of the casting process and in selecting the shape of the riser for the casting fed with it. These actions are aimed at leading shrinkage defects to the riser, so that the casting remains free from this type of defects. Since shrinkage defects usually disqualify the casting from its further use, this type of research is still valid and requires further work. The paper presents the mathematical model and the results of numerical simulations of the casting solidification process obtained by using the Finite Element Method (FEM). A partial differential equation describing the course of thermal phenomena in the process of 3D casting creating was applied. This equation was supplemented with appropriate boundary and initial conditions that define the physical problem under consideration. In numerical simulations, by selecting the appropriate shape riser, an attempt was made to obtain a casting without internal defects, using a simple method of identifying their location. This is the main aim of the research as such defects in the casting disqualify it from use.
    Źródło:
    Archives of Metallurgy and Materials; 2022, 67, 1; 181-187
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The identification of Anaplasma spp. isolated from fallow deer (Dama dama) on a free-range farm in eastern Poland
    Autorzy:
    Adaszek, L.
    Klimiuk, P.
    Skrzypczak, M.
    Gorna, M.
    Zietek, J.
    Winiarczyk, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/32373.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of the present study was to investigate the occurrence of Anaplasma spp. in group of 50 fallow deer (Dama dama) from free-range farm in eastern Poland and determine what species of Anaplasma could infect these animals based on PCR gene sequencing. The PCR technique revealed the presence of 16S RNA Anaplasma spp. genetic material in the blood of 7 out of 50 examined animals. The sequences of the PCR products obtained showed a 100% homology with each other and 100% homology with GU 183908 sequence of A. phagocytophilum, isolated in our earlier study from a horse with clinical form of anaplasmosis. Here, we report the first molecular evidence of Anaplasma spp. among naturally infected fallow deer in eastern Poland.
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical course of granulocytic anaplasmosis in hunting dogs
    Autorzy:
    Teodorowski, O.
    Winiarczyk, S.
    Debiak, P.
    Skrzypczak, M.
    Mazurek, Ł.
    Adaszek, Ł.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087166.pdf
    Data publikacji:
    2021
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Anaplasma phagocytophilum
    hunting dog
    vector-borne disease
    Źródło:
    Polish Journal of Veterinary Sciences; 2021, 24, 2; 175-181
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular analysis of a fragment of gene E1B 19K of canine adenovirus 2 (CAV-2) isolated from dogs with symptoms of cough
    Autorzy:
    Kalinowski, M.
    Adaszek, L.
    Miloszowska, P.
    Skrzypczak, M.
    Zietek-Barszcz, A.
    Kutrzuba, J.
    Gradzki, Z.
    Winiarczyk, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/31384.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    molecular analysis
    gene
    canine adenovirus 2
    isolation
    dog
    disease symptom
    cough
    upper respiratory tract infection
    Opis:
    The aim of this study was to perform molecular analysis of canine adenovirus 2 (CAV-2) E1B 19K gene fragment isolated from 20 dogs of various breeds (12 males and 8 females aged 1-9 years), with clinical symptoms of upper respiratory tract infections, from the Lubelszczyzna region. Nasal swabs were taken from dogs. DNA of CAV-2 was detected using the PCR method in 16 swabs. All PCR products were sequenced, and the obtained sequences were compared with each other and with the sequence of the E1B 19K gene of the CAV-2 strain from an online database of NCBI GenBank: AC 000003. Based on analysis of the obtained sequences, three polymorphic variants of CAV-2 (No.1-3) with homology of 78 - 100% were distinguished. The nucleotide and amino acid sequences of the most frequently represented polymorphic variant, No. 1, differed from the sequences of polymorphic variant No. 2 with one substitution. The nucleotide and amino acid sequence of the E1B 19K gene of CAV-2 AC 000003 differed from the analogous sequences of representatives of variant No. 1 with 44 nucleotide and 19 amino acid substitutions. The small number of nucleotide differences in the E1B 19K CAV-2 gene among the examined own isolates, compared with AC 000003, suggest that the infections in dogs were caused by a relatively genetically stable virus which occurs in eastern Poland.
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry for identification of coagulase-negative staphylococci isolated from milk of cows with subclinical mastitis
    Autorzy:
    Banach, T.
    Bocniarz, M.
    Lyp, P.
    Adaszek, L.
    Wawron, W.
    Furmaga, B.
    Skrzypczak, M.
    Zietek, J.
    Winiarczyk, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/31177.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of this study was to use matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the identification of coagulase-negative staphylococci (CNS) isolated from the milk of cows with subclinical mastitis. The study material consisted of 33 isolates of CNS, identified by the results of API Staph tests, obtained from the milk of cows with subclinical mastitis. Based on the spectra analyses, MALDI-TOF MS tests of 33 bacterial samples allowed identification of the microorganisms in 27 cases (81.8%). The most frequent cause of subclinical mastitis was found to be Staphylococcus sciuri (39%), while S. vitulinus was detected in 15% of the milk samples. The results obtained indicate that MALDI-TOF MS can be used for the identification of CNS isolated from bovine mastitis as a method supplementary to biochemical tests.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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