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Wyświetlanie 1-2 z 2
Tytuł:
Microstructural Characterization of the As-cast AZ91 Magnesium Alloy with Rare Earth Elements
Autorzy:
Grzybowska, A.
Braszczyńska-Malik, K.
Powiązania:
https://bibliotekanauki.pl/articles/382210.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Mg-Al-Zn alloy
rare earth elements
microstructure
stop Mg-AI-Zn
pierwiastki ziem rzadkich
mikrostruktura
Opis:
Microstructural analysis of as-cast Mg-9Al-0.9Zn-xRE (x = 0, 1, 2, 3, 5 wt.%) magnesium alloys is presented. Light microscopy (LM) and scanning electron microscopy (SEM+EDX) were used to characterized the obtained material. The results revealed that the as-cast AZ91 alloy consists of α – Mg matrix, binary eutectic α + γ (where γ is Mg17Al12). While rare earth elements were introduced to the Mg-Al-Zn alloy new Al11RE3 phase was formed. Additionally, in the experimental alloys instead of Al-Mn phase, ternary Al-Mn-RE compound was observed. What is more, the influence of RE addition on the area fraction of eutectic and needle-like phase was analysed. With increasing addition of RE, the amount of γ phase decreased, but the amount of Al11RE3 phase increased.
Źródło:
Archives of Foundry Engineering; 2012, 12, 2s; 23-26
1897-3310
2299-2944
Pojawia się w:
Archives of Foundry Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Relevance of molecular changes in the ND4 gene in German Shepherd dog tumours
Autorzy:
Slaska, B.
Grzybowska-Szatkowska, L.
Bugno-Poniewierska, M.
Gurgul, A.
Smiech, A.
Rozanska, D.
Dudka, J.
Powiązania:
https://bibliotekanauki.pl/articles/31142.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
The aim of the study was to identify polymorphisms and mutations in the mitochondrial ND4 gene and to analyse the associations between the occurrence of molecular changes in mtDNA and phenotypic traits in tumours in German Shepherd dogs. Fifty samples obtained from blood and tumour tissues of German Shepherd dogs with diagnosed tumours were analysed. DNA extraction, amplification, and sequencing of the mtDNA ND4 gene, and bioinformatics, statistical, and in silico protein coding SNP analyses were performed. ND4 mutations and/or polymorphisms were noted in eleven nucleotide positions in nearly half of the examined dogs. All the changes were substitution mutations. A majority of the changes identified were homoplasmic. In one dog with osteosarcoma, blood heteroplasmy was detected. In two positions of the ND4 gene, presence of non-synonymous mutations leading to amino acid changes in the ND4 protein was reported. Analyses carried out to determine the deleterious effect of mutations indicated an almost 97 and 62% probability that a single amino acid substitution (p.G239V and p.I401T, respectively) in the protein has a negative impact on its function. The results of statistical analyses indicate a significant association between the occurrence of mutations in three loci of the ND4 gene and the location of tumours. The mutations identified may be a result of cell adaptation to the changes in the environment occurring during carcinogenesis. The high frequency of mutations in the tumours may indicate genetic instability of mtDNA, which may also play a role in carcinogenesis.
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 3
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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