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    Wyświetlanie 1-8 z 8
    Tytuł:
    DNA – a molecule that transformed science. A short history of research
    Autorzy:
    Gabryelska, Marta M.
    Szymański, Maciej
    Barciszewski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/703398.pdf
    Data publikacji:
    2009
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    DNA
    molecular biology
    genomics
    genetics
    Opis:
    Deoxyribonucleic acid (DNA) was identified 140 years ago by a Swiss physician Friedrich Miescher. His discovery was fundamental for the development of biochemistry, genetics and molecular biology. Contemporary biology, biotechnology and medicine largely depends on our ability to analyze, synthesize and manipulate DNA. We present highlights of the history of DNA research from the very beginning to the sequencing of human genome.
    Źródło:
    Nauka; 2009, 2
    1231-8515
    Pojawia się w:
    Nauka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Theory of organic being by Jędrzej Śniadecki. Revolutionary look at phenomenon of life
    Autorzy:
    Zubek, Aniela
    Barciszewski, Jakub
    Belter, Agnieszka
    Barciszewski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/703616.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Jędrzej Śniadecki
    Theory of organic being
    what is life?
    Opis:
    In 2018 we celebrate the 250th anniversary of the Jędrzej Śniadecki’s birth. This work aims to show the importance of his thoughts for the development of natural sciences. He studied at some of the largest universities in Europe, where he met great scientists of the Enlightenment. The effects can be seen in his works. He was remembered as a founder of Polish biochemistry, anthropology and pathology, also as the author of chemical terminology and  language. The essence of his thoughts is Theory of organic being, which is an attempt to answer the question: „what is life?”. Jędrzej Śniadecki introduced a new definition of life based on the term „organic power”. This work shows how import are the thoughts of Jędrzej Śniadecki in the context of the times in which he lived, as well as the following development of natural sciences, what makes him and his theories worth memory.
    Źródło:
    Nauka; 2018, 4
    1231-8515
    Pojawia się w:
    Nauka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Regulatory RNAs in the brain
    Autorzy:
    Gabryelska, Marta
    Szymański, Maciej
    Barciszewska, Mirosława Z.
    Barciszewski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/704277.pdf
    Data publikacji:
    2008
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    brain
    non-coding RNAs
    gene expression
    diseases
    Opis:
    Nervous system is characterized by its uniqueness in cells origin, their variability, electrical properties of the nervous cell membrane, response to external signals, neuronal network and changes in synapses activity that are the basis of higher brain functions, such as learning and memory. Brain is a superior organ of human body with an extremely efficient regulation system. Apart from protein and small-molecule regulators, ribonucleic acids (RNAs), especially noncoding proteins (ncRNAs), play a crucial controlling role in the brain. They are present in every cell, from bacteria to primates and have regulatory, catalytic as well as structural function. Many specific ncRNAs have been identified in human brain, responsible for development and functioning. Disturbances in ncRNA synthesis and mechanism of action are connected to diseases such as autism, schizophrenia, Alzheimer disease, Prader-Willi syndrome and others.
    Źródło:
    Nauka; 2008, 2
    1231-8515
    Pojawia się w:
    Nauka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Psychology goes molecular. Epigenetics of learning
    Autorzy:
    Barciszewski, jan
    Gurda, Dorota
    Paluchowski, Władysław Jacek
    Hornowska, Elżbieta
    Jasielska, Aleksandra
    Powiązania:
    https://bibliotekanauki.pl/articles/703903.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    behavioral epigenetics
    cognitive functions
    DNA methylation
    epigenetic inheritance
    epigenetics
    gene-environment interplay
    learning
    memory
    Opis:
    The challenge for psychology is to integrate findings from genetics and environmental (social, biological, chemical) factors, into the study of human behavior and deep understanding of the emergence of different changes in the anatomy, physiology, and chemistry of the nervous system that influence the mental health. Currently, cognitive abilities associated with learning and memory, reasoning, problem solving, and developing relationships are in scope of molecular psychology, which is the study of behavior and its underlying brain systems using the tools of molecular biology. However, studies have demonstrated that DNA sequence variations and rare mutations account for only a small fraction of the risk for inheritance of personality traits and mental illness. The large unaccounted heritability of personality traits and mental health suggest that additional molecular and cellular mechanisms are involved. Various complex gene-environment interactions can lead to different phenotypes. These structural changes may be crucial for the development of mature neural networks that support emotional, cognitive, and social behavior. The generation of different morphology, physiology, and behavioral outcomes from a single genome in response to changes in the environment forms the basis for phenotypic plasticity, which is fundamental to the way organisms cope with environmental variation, navigate the present world, and solve future problems. Epigenetics has major implications for psychology and gives the new answer for the old question- what is the biochemical basis of learning. It is bringing back the leading role of environment and behavior, by including their effects on genome function. In addition, it opens up the possibility of memory being stored in the epigenome, so that our experiences may be embedded in our genome by epigenetic mechanisms. Epigenetics can be described as the study of the complex interactions underlying the development of an organism over its lifetime.
    Źródło:
    Nauka; 2016, 4
    1231-8515
    Pojawia się w:
    Nauka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sesquicentennial of the discovery of DNA. Forgotten Professor Richard Altmann from Iława
    Autorzy:
    Zubek, Aniela
    Belter, Agnieszka
    Naskręt-Barciszewska, Mirosława Z.
    Stefan, Jurga
    Markiewicz, Wojciech T.
    Barciszewski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/704410.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Richard Altmann
    DNA
    nucleic acids
    mitochondria
    Opis:
    This year we are celebrating 150 anniversary of the discovery of DNA by Friedrich Miescher. His finding initiated a series of discoveries that allowed to depicts life's most famous molecule with novel features with considerable biological interest. In this article we recall the biggest mile stones of 150-year history of DNA and present the context and meaning of several key observations that have brought us closer to understanding DNA. 150 years ago, people had no idea that DNA existed, and they certainly hadn’t heard of DNA structure and sequencing. We now know that DNA is a dynamic, tortuous coil, constantly shuffling and unwinding. Today DNA is all around us, in a physical sense and in a cultural sense. It is really part of our culture. We will discuss also the little known facts, often overlooked in similar discussions. We will focus particularly on Professor Richard Altmann's from Iława, whose contribution to knowledge about nucleic acids is significant, although not well recognized so far.
    Źródło:
    Nauka; 2019, 1
    1231-8515
    Pojawia się w:
    Nauka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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