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    Wyświetlanie 1-2 z 2
    Tytuł:
    An approximation algorithm for multi-unit auctions: numerical and subject experiments
    Autorzy:
    Takahashi, S.
    Izunaga, Y.
    Watanabe, N.
    Powiązania:
    https://bibliotekanauki.pl/articles/406625.pdf
    Data publikacji:
    2018
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    multi-unit auctions
    approximation algorithm
    experiment
    algorytm aproksymacyjny
    eksperyment
    Opis:
    In multi-unit auctions for a single item, the Vickrey–Clarke–Groves mechanism (VCG) attains allocative efficiency but suffers from its computational complexity. Takahashi and Shigeno thus proposed a greedy based approximation algorithm (GBA). In a subject experiment there was truly a difference in efficiency rate but no significant difference in seller’s revenue between GBA and VCG. It is not clear in theory whether each bidder will submit his or her true unit valuations in GBA. We show, however, that in a subject experiment there was no significant difference in the number of bids that obey “almost” truth-telling between GBA and VCG. As for individual bidding behavior, GBA and VCG show a sharp contrast when a human bidder competes against machine bidders; underbidding was observed in GBA, while overbidding was observed in VCG. Some results in a numerical experiment are also provided prior to reporting those observations.
    Źródło:
    Operations Research and Decisions; 2018, 28, 1; 95-115
    2081-8858
    2391-6060
    Pojawia się w:
    Operations Research and Decisions
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Determination of optimal cyclic uniaxial stretches for stem cell-to-tenocyte differentiation under a wide range of mechanical stretch conditions by evaluating gene expression and protein synthesis levels
    Autorzy:
    Morita, Y.
    Watanabe, S.
    Ju, Y.
    Xu, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/951825.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    hBMSC
    differentiation
    mechanical stretch
    tenocyte
    różniczkowanie
    wydłużanie
    Opis:
    We examined optimal cyclic uniaxial stretches for stem cell-to-tenocyte differentiation by applying a wide range of cyclic mechanical stimuli. Human bone marrow mesenchymal stem cells (hBMSCs) were subjected to three types of cyclic elongation of 5%, 10%, or 15% at a cyclic frequency of 1 Hz for 24 h or 48 h, and differentiation into tenocytes was assessed by two methods: real-time polymerase chain reaction determination of gene expression levels and western blotting analysis of protein expression levels. The gene expression levels of the differentiation markers type I collagen (Col I), type III collagen (Col III), tenascin-C (Tnc), and scleraxis (Scx), all of which are constituents of tendon tissue, were increased when cells were exposed to 10% stretching stimulation. The levels of Col I and Tnc protein synthesis levels were also higher in the cells with 10% stretching stimulation than in those subjected to other stimuli. The results indicated that 10% stretching stimulus was efficient to induce the differentiation of hBMSCs into tenocytes. In addition, the changes in gene and protein expression levels were strongly correlated with cell orientation angle. The results presented here suggest that mesenchymal stem cell-to-tenocyte differentiation is strongly associated with cumulative elongation load on the cells. This work provides novel insights into the differentiation of tenogenesis in a strain-induced environment and supports the therapeutic potential of hBMSCs.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2013, 15, 3; 71-79
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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