- Tytuł:
- Non-thermal plasmas induced electrostatic stress on corneocyte desquamation
- Autorzy:
-
Tiwari, P. K.
Lee, Y. S. - Powiązania:
- https://bibliotekanauki.pl/articles/306974.pdf
- Data publikacji:
- 2013
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Tematy:
-
corneocyte
stratum corneum
desquamation
electrostatic
disruption
zakłócenie
łuszczenie się
elektrostatyczność - Opis:
- The advent of non-thermal plasma brought a breakthrough in exploring its clinical applications in dermatology to bolster tissue generation in the domain of plasma medicine. This study aimed to investigate the effect of non-thermal plasma on the corneocyte of the skin cells, in treating superficial skin diseases via the process of corneocyte desquamation, a probable mechanism for skin cell proliferation. The postulated brick and mortar arrangement of corneocytes in the stratum corneum was modeled consisting of three corneocytes and three corneodesmosomes in a simulation domain of 40.30 × 3.00 μm2 using Maxwell 2D finite element analyzer. The corneocyte desquamation was quantified by the weakening of corneodesmosomes due to electrostatic pressure (~530 MV/m) on the corneodesmosome surface exceeding its tensile strength (~76 MPa). A mathematical model displaying a relationship between the plasma potential and the skin tensile strength is also presented in this investigation. The non-thermal plasma could emerge as a clean and dry therapy to treat superficial skin diseases. Our study propels investigating the interaction of non-thermal plasma with the wet tissue in the deeper layer (dermis) of the skin cells and also, the development of such instruments for a comprehensive skin treatment.
- Źródło:
-
Acta of Bioengineering and Biomechanics; 2013, 15, 2; 65-72
1509-409X
2450-6303 - Pojawia się w:
- Acta of Bioengineering and Biomechanics
- Dostawca treści:
- Biblioteka Nauki
Artykuł