- Tytuł:
- Corrosion resistance of PLGA-coated biomaterials
- Autorzy:
-
Szewczenko, J.
Kajzer, W.
Grygiel-Pradelok, M.
Jaworska, J.
Jelonek, K.
Nowińska, K.
Gawliczek, M.
Libera, M.
Marcinkowski, A.
Kasperczyk, J. - Powiązania:
- https://bibliotekanauki.pl/articles/306888.pdf
- Data publikacji:
- 2017
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Tematy:
-
odporność korozyjna
stopy tytanu
stal nierdzewna
PLGA
corrosion resistance
titanium alloys
stainless steel
degradation
biodegradable coatings - Opis:
- The aim of the study was to determine the influence of PLGA bioresorbable polymer coating on corrosion resistance of metal biomaterial. Polymer coating deposited by immersion method was applied. Corrosion resistance of metal biomaterials (stainless steel, Ti6Al4V, Ti6Al7Nb) coated with PLGA polymer, after 90 days exposure to Ringer’s solution was tested. The amount of metal ions released to the solution was also investigated (inductively coupled plasma–atomic emission spectrometry (ICP-AES) method). The surface of the samples was observed using atomic force microscopy (AFM) and scanning electron microscopy (SEM). Degradation of PLGA was monitored with the use of the 1 H NMR spectroscopy and GPC (Gel Permeation Chromatography). The studies were carried out for non-sterilized (NS) and sterilized (S) samples. Application of the polymer coating causes a reduction of release of metal ions to the solution. Depending on metal substrate different course of destruction of polymer layer was observed. After 90 days of incubation in Ringer’s solution polymer layer was highly degraded, however, the composition of copolymer (ratio of the comonomeric units in the chain) remained unchanged during the whole process, which suggests even degradation. The polymer layer reduced degradation kinetics of the metal substrate. Moreover, degradation process did not change surface morphology of metal substrate and did not disturb its integrity. The results obtained indicate that the applied polymer layer improves corrosion resistance of the alloys being investigated. Thus, the developed implants with bioresorbable coatings could be advantageous for medical applications.
- Źródło:
-
Acta of Bioengineering and Biomechanics; 2017, 19, 1; 173-179
1509-409X
2450-6303 - Pojawia się w:
- Acta of Bioengineering and Biomechanics
- Dostawca treści:
- Biblioteka Nauki
Artykuł