Wszystkie pola: Chmielewska, E. - Katalog OPAC zbiorów

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Tytuł:: In vitro assay of the biological activity of bisphosphonates
Autorzy:: Chmielewska, E.
Miszczyk, P.
Kafarski, P.
Kempińska, K.
Wietrzyk, J.
Powiązania:: https://bibliotekanauki.pl/articles/1190037.pdf
Data publikacji:: 2015
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: bisfosfoniany
cytotoksyczność
in vitro
aktywność biologiczna
inhibitor
bisphosphonates
cytotoxicity
biological activity
Opis:: Nowadays, the use of bisphosphonates are the gold standard of treatment of bone diseases. Due to the high utility of these compounds, scientists still search for better and better structures, with a variety of substituents at carbon’s atom and create new libraries or improve methods of their synthesis. To determine the potential effect of newly discovered bisphosphonates, for example antiosteoporotic activity, there are in vitro tests which allow to determine the half maximal inhibitory concentrations (IC50) of cells. This paper describes in detail the methodology for test the biological activity of bisphosphonates. Shows the results of biological activity for synthesized bisphosphonates in relation to the commercial-incadronate and zoledronate.
Źródło:: Interdisciplinary Journal of Engineering Sciences; 2014, 2, 1; 13--16
2300-5874
Pojawia się w:: Interdisciplinary Journal of Engineering Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Bioelectrical activity of the pelvic floor muscles after 6-week biofeedback training in nulliparous continent women
Autorzy:: Chmielewska, D.
Stania, M.
Smykla, A.
Kwaśna, K.
Błaszczak, E.
Sobota, G.
Skrzypulec-Plinta, V.
Powiązania:: https://bibliotekanauki.pl/articles/306365.pdf
Data publikacji:: 2016
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: elektromiografia
biofeedback
zdrowi ochotnicy
profilaktyka
pelvic floor
electromyography
healthy volunteers
prevention
Opis:: Purpose: The aim of the study was to evaluate the effects of a 6-week sEMG-biofeedback-assisted pelvic floor muscle training program on pelvic floor muscle activity in young continent women. Methods: Pelvic floor muscle activity was recorded using a vaginal probe during five experimental trials. Biofeedback training was continued for 6 weeks, 3 times a week. Muscle strenghtening and endurance exercises were performed alternately. SEMG (surface electromyography) measurements were recorded on four different occasions: before training started, after the third week of training, after the sixth week of training, and one month after training ended. Results: A 6-week sEMG-biofeedback-assisted pelvic floor muscle training program significantly decreased the resting activity of the pelvic floor muscles in supine lying and standing. The ability to relax the pelvic floor muscles after a sustained 60-second contraction improved significantly after the 6-week training in both positions. SEMG-biofeedback training program did not seem to affect the activity of the pelvic floor muscles or muscle fatigue during voluntary pelvic floor muscle contractions. Conclusions: SEMG-biofeedback-assisted pelvic floor muscle training might be recommended for physiotherapists to improve the effectiveness of their relaxation techniques.
Źródło:: Acta of Bioengineering and Biomechanics; 2016, 18, 3; 105-113
1509-409X
2450-6303
Pojawia się w:: Acta of Bioengineering and Biomechanics
Dostawca treści:: Biblioteka Nauki

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