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Wyświetlanie 1-3 z 3
Tytuł:
Purification and Characterization of a Low Molecular Weight Neutral Non-Starch Polysaccharide from Panax ginseng by Enzymatic Hydrolysis
Autorzy:
Ying, Ying
Ma, Chao
Zhang, Yajie
Li, Xiaoping
Wu, Hongxin
Powiązania:
https://bibliotekanauki.pl/articles/16538536.pdf
Data publikacji:
2023-02-21
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
ginseng polysaccharide
chromatographic separation
monosaccharide composition
structure analysis
Opis:
In this study, a novel neutral non-starch polysaccharide (GP1A) was extracted using hot water from ginseng roots. Chemical characteristics, monosaccharide compositions and structure of GP1A were investigated using scanning electron microscopy, gel permeation chromatography, X-ray diffraction, Fourier transform infrared spectroscopy, gas chromatography with mass spectrometer, one-dimensional and two-dimensional nuclear magnetic resonance. The results indicated that the lyophilized GP1A was a homogeneous polysaccharide with a low molecular weight of 1.03 kDa. The dominating monosaccharides of GP1A were D-glucose, D-galactose, D-mannose, D-xylose and D-arabinose. The structure analysis indicated the main chain residues sequence of GP1A was α-D-Glcp-(6→3)-α-D-Galp-(1→1)-α-D-Glcp-(3→4)-β-D-Manp-(2→2)-β-D-Arap with branch chains of α-D-Glcp substituted at α-D-Galp and β-D-Xylp substituted at β-D-Manp.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2023, 73, 1; 70-79
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enhancement of the Stabilities and Intracellular Antioxidant Activities of Lavender Essential Oil by Metal-Organic Frameworks Based on β-Cyclodextrin and Potassium Cation
Autorzy:
Wang, Ying
Wang, Liang
Tan, Jin
Li, Rong
Jiang, Zi-Tao
Tang, Shu-Hua
Powiązania:
https://bibliotekanauki.pl/articles/1363277.pdf
Data publikacji:
2021
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
microcapsulation
thermal stability
pH stability
cell viability
cellular antioxidant model
application extension
Opis:
Lavender (Lavandula angustifolia) is an important medicinal and aromatic plant. However, the application of lavender essential oil (LEO) is limited by its instability, low solubility and high volatility. Therefore, to improve the stabilities and antioxidant activities of LEO and thereby expand the applications, LEO was microencapsulated by metal-organic frameworks based on β-cyclodextrin and potassium cation (K-βCD-MOFs) with different mass core/wall ratios. The results showed that the best inclusion rate was 96.67% with the ratio of 1:10. Then, the optimum inclusion product was characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM). The thermal and pH stabilities and the intracellular antioxidant activities were also studied. The results showed that the stabilities of the oil with K-βCD-MOFs inclusions and their abilities to resist acid and alkali were significantly stronger than those of LEO itself. In addition, the intracellular antioxidant activities of LEO were also enhanced by the K-βCD-MOFs inclusion. These results suggested the potential of K-βCD-MOFs as carriers for essential oils in food industry applications.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2021, 71, 1; 39-50
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Curcumin Prevents Free Fatty Acid-Induced Lipid Accumulation via Targeting the miR-22-3p/CRLS1 Pathway in HepG2 Cells
Autorzy:
Mei, Yuanyuan
Sun, Xiaoting
Huang, Shi-Ying
Wu, Xiaowen
Ho, Kuo-Ting
Lu, Liming
Chen, Chaoxiang
Li, Jian
Liu, Jingwen
Li, Guiling
Powiązania:
https://bibliotekanauki.pl/articles/28408450.pdf
Data publikacji:
2024-02-13
Wydawca:
Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:
polyphenol
epigenetics
liver
steatosis
mitochondria
Opis:
Dysregulated lipid metabolism in liver is an important hallmark of non-alcoholic fatty liver disease (NAFLD), which may be modulated by dietary polyphenols or microRNAs (miRNAs). However, the underlying epigenetic regulatory mechanism of polyphenols remain unclear. The current study aimed to address how miRNA mediates hepatic lipid metabolic control of curcumin, a polyphenolic food supplement. The results showed that 24 h treatment with 5 - 20 μM curcumin prevented free fatty acid-induced lipid accumulation by around 10 ~ 50% in HepG2 cells, which was attenuated by pre-transfection with 40 nM miR-22-3p mimic for 48 h. In consequence, transfection with 40 nM miR-22-3p inhibitor for 48 h significantly reduced lipid accumulation by around 10%. And 48 h overexpression of miR-22-3p targeting cardiolipin synthase 1 (CRLS1) gene, which encodes a mitochondrial phospholipid synthase, showed a similar regulatory effect. Thus, miR-22-3p and CRLS1 showed opposite effects in modulating lipid metabolism, which probably involved mitochondrial control. In summary, this study demonstrated that curcumin improved hepatic lipid metabolism via targeting the miR-22-3p/CRLS1 pathway. Identification of the epigenetic regulatory mechanism underlying lipid metabolism may thereby facilitate alleviation of metabolic disorders by natural polyphenols.
Źródło:
Polish Journal of Food and Nutrition Sciences; 2024, 74, 1; 59-68
1230-0322
2083-6007
Pojawia się w:
Polish Journal of Food and Nutrition Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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