Temat: cardiovascular - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Ischemic cardiovascular disease in workers occupationally exposed to urban air pollution - a systematic review
Autorzy:: De Marchis, P.
Verso, M.G.
Tramuto, F.
Amodio, E.
Picciotto, D.
Powiązania:: https://bibliotekanauki.pl/articles/2081525.pdf
Data publikacji:: 2018
Wydawca:: Instytut Medycyny Wsi
Tematy:: air pollution
infarction
cardiovascular
Opis:: Introduction. Cardiovascular disease is the first cause of morbidity and mortality worldwide. Among several known risk factors, researchers also focus their attention on the chronic exposure to air pollution. There is much evidence that exposure to air pollution, especially to ultrafine particles, can damage the endothelium and can favour cardiovascular diseases in the general population. Occupational exposition could be an additive risk factor for the cardiovascular system. This article presents a scientific review of the linkage between occupational exposure to air pollution and ischemic heart disease. Materials and method. A scientific review was undertaken, followed by PRISMA Statements. Observational studies were selected from several scientific databases, likesuch as Pubmed, Google Scholar, Nioshtic-2 and Reserchgate, searching for selected key words: police workers, professional drivers, mail carriers, filling station attendants, road cleaners, garage workers, motor vehicles and engine maintenance. All the key words were combined with “Boolean Operators” with the following words: cardiovascular (or cardiac) disease, cardiovascular function, cardiovascular system, ischemic heart disease, coronary disease, myocardial infarction. During the systematic research, the focus was on retrospective and prospective studies from January 1990 – December 2014. Results. Both the retrospective and prospective studies showed an increased risk of ischemic heart disease in occupationally occupied people exposed to air pollution. Only one study presented a ly minor risk. Conclusions. The findings of this systematic review suggest a possible linkage between occupational exposure to urban air pollution, especially to motor exhaust and particulate, and ischemic heart disease.
Źródło:: Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 162-166
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Prevalence of hypertension and major cardiovascular risk factors in healthy residents of a rural region in south-eastern Poland - 1997–2008/9
Autorzy:: Płaczkiewicz, Daniel
Puźniak, Marek
Kleinrok, Andrzej
Powiązania:: https://bibliotekanauki.pl/articles/989090.pdf
Data publikacji:: 2016
Wydawca:: Instytut Medycyny Wsi
Tematy:: risk factors
cardiovascular diseases
rural population
Opis:: Introduction and objective. The aim of this study was to show the prevalence of hypertension and major risk factors of cardiovascular disease among healthy adults in an agricultural region of south-eastern Poland, and the changes which have occurred in this area during the 12-year follow-up. Materials and method. 1,233, mostly rural inhabitants of Zamosc County without previous history of diabetes and CVD were subjected to analysis. Prevalence of hypertension and major cardiovascular risk factors were evaluated. Changes in the prevalence of risk factors between 1997 – 2008 were analyzed. Results. 33.0% of the examined population are active smokers, and there was a 1.8-fold increase (p = 0.0009). The percentage of people with hypercholesterolemia between 1997 – 2008/9 increased almost 2-fold (p<0.0001) and now it is 62.3%. The number of people with high blood pressure decreased nearly by a half (46%, p <0001) and it is currently 25.8%. Improper waist circumference was observed in 32.8% of the population (33.1% women, 26.5% men). Abdominal obesity decreased among men (48%; p=0.0008) and rural residents (29%, p=0.01). In comparison with 1997, in 2008 2009, the cardiovascular risk assessed using SCORE tables increased. The percentage of people with high-risk (≥5%) almost tripled in the general population (p=0.0183) and increased 4-fold in men (p=0.0145). Conclusions. Detection of hypertension in the rural region in which the survey was carried out is still too low. Actions against tobacco addiction should be a major component of health-education programmes for the rural areas of south-eastern Poland.
Źródło:: Annals of Agricultural and Environmental Medicine; 2016, 23, 3
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: High-density lipoprotein (HDL) cholesterol - more complicated than we think?
Autorzy:: Nessler, K.
Windak, A.
Grzybczak, R.
Nessler, M.B.
Siniarski, A.
Gajos, G.
Powiązania:: https://bibliotekanauki.pl/articles/2081847.pdf
Data publikacji:: 2018
Wydawca:: Instytut Medycyny Wsi
Tematy:: cardiovascular disease
diabetes mellitus
dysfunctional HDL
Opis:: Introduction and objective. There are some clinical situations where a high level of HDL cholesterol (HDL-C) may be unfavourable. In these situations, HDL-C may undergo some changes, and even if its quantity is within the reference range, its quality is no longer the same. Brief description of state of knowledge. Diabetes is the state of elevated oxidative stress. Studies conducted to-date have revealed an increased production of the reactive forms of oxygen as the result of tissue damage in diabetes patients. The expression ‘dysfunctional HDL’ has been coined in the literature to describe high-density lipoproteins that lose their antioxidative and anti-inflammatory properties, that is, HDL-C that loses its basic functions. Recent observational studies have confirmed that the atheroprotective activity of properly functioning HDL-C is frequently impaired in clinical situations associated with oxidative stress. The presented review lays the foundation for a new approach to understanding how the functional properties of HDL help reduce cardiovascular risk. Conclusions. In the light of presented findings it seems that there is a need to seek a better diagnostic marker than HDL-C level. This study presents some possible directions for future research to bring us closer to the full understanding of the HDL particle and its role in patients with ischemic heart disease and type 2 diabetes.
Źródło:: Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 517-526
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: Prevention of cardiovascular disease in a rural general practice
Autorzy:: Tomiak, Elżbieta
Chlabicz, Sławomir
Mizgała, Elżbieta
Lukas, Witold
Panasiuk, Lech
Drzastwa, Witold
Jankowska-Zduńczyk, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/987099.pdf
Data publikacji:: 2016
Wydawca:: Instytut Medycyny Wsi
Tematy:: cardiovascular risk factors
prevention
primary care
Opis:: Introduction. Cardiovascular disease (CVD) prophylaxis in general practice, especially in rural areas, is a major organizational challenge. Objective. The aim of this study was to determine the prevalence of CVD risk factors in the studied population, and to identify the effect of the number of planned prophylactic consultations on selected clinical parameters, risk factors, and total cardiovascular risk on the SCORE scale (Systemic Coronary Risk Evaluation). Materials and method. The study included patients of a rural general practice, aged 35–55 years, with at least one modifiable CVD risk factor. Medical history was obtained, a physical examination performed, blood glucose levels, lipid profile, BMI, waist circumference and blood pressure measured and the SCORE cardiovascular risk at baseline and at the end of the study calculated. All participants were provided with targeted specific education. Analysis was performed in two groups of patients (1 and 2), where group 1 had one more prophylactic consultation than Group 2. Results. The results at baseline and a year later were compared in pharmacologically untreated patients, 26 in Group 1 and 34 in Group 2. In Group 1, which had had more prophylactic consultations, a statistically significant decrease was found in the mean systolic blood pressure: 131.000–124.782 (p= 0.02721), mean diastolic blood pressure: 86.846–83.462 (p=0.01111), and a statistically significant decrease in total cardiovascular risk on the SCORE scale (p=0.0478). Conclusions. The higher number of preventive consultations had an impact on a statistically significant decrease in mean blood pressure and mean SCORE value. The year-long cardiovascular disease prophylaxis programme proved less effective than expected, and neither a decrease in body weight nor an improvement in lipid metabolism was achieved in any of the groups.
Źródło:: Annals of Agricultural and Environmental Medicine; 2016, 23, 4
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 5.

Tytuł:: Assessment of knowledge on cardiovascular disease risk factors by postal survey in residents of Malopolska Voivodeship. Malopolska CArdiovascular PReventive Intervention Study (M-CAPRI)
Autorzy:: Waśniowska, Anna
Kopeć, Grzegorz
Szafraniec, Krystyna
Misiowiec, Witosława
Waligóra, Marcin
Brózda, Mateusz
Sarnecka, Agnieszka
Podolec, Jakub
Orzeł-Nowak, Anita
Pająk, Andrzej
Podolec, Piotr
Powiązania:: https://bibliotekanauki.pl/articles/989864.pdf
Data publikacji:: 2017
Wydawca:: Instytut Medycyny Wsi
Tematy:: cardiovascular disease
health knowledge
risk factors
postal survey
Opis:: Introduction. Education is a key tool in the prevention of cardiovascular disease (CVD). Education programmes require monitoring of their effectiveness. Objectives. 1) to introduce postal screening for the assessment of knowledge on CVD risk factors (RFs) for the Polish population, 2) to assess this knowledge in adult residents of Małopolska Voivodeship, and 3) to assess whether knowledge on RFs is related to age, gender, place of residence, level of education and family history of CVD. Materials and method. Anonymous questionnaires were posted to a random sample of 5,000 residents of Małopolska Voivodeship in Poland. Results were presented as proportions of participants who listed RFs correctly. A series of multiple logistic regression models was used to assess the associations of knowledge on RFs with the potential determinants. Results. 1,126 completed questionnaires were returned. Over 35% of respondents could not list a single RF and 14 % listed only 1–2 RFs. About 40% named 3–5 and only 12% listed 6 or more RFs. About a half of the respondents listed incorrectly from 1–8 characteristics as being associated with higher risk of CVD. In the multivariate analysis, knowledge on RFs was not significantly associated with age. Level of education was the strongest determinant of knowledge. Male rural and small town residents had less knowledge, whereas women with a family history of CVD had more knowledge on some CVD RFs. Conclusions. Using a postal questionnaire for the assessment of knowledge of CVD RFs in the population of Małopolska Voivodeship appeared to have serious limitations due to low participation in the study. Despite this, the results of the study indicate that knowledge on CVD RFs is insufficient. Female gender and higher education were related to more prevalent knowledge on RFs. Family history of CVD was related to better knowledge in women only. Male residents of rural areas and small towns had slightly less knowledge on CVD RFs.
Źródło:: Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 6.

Tytuł:: Factors determining health behaviours of the 50plus population with cardiovascular diseases
Autorzy:: Gąska, I.
Sygit, K.M.
Cipora, E.
Sygit, M.
Krakowiak, J.
Powiązania:: https://bibliotekanauki.pl/articles/2085406.pdf
Data publikacji:: 2020
Wydawca:: Instytut Medycyny Wsi
Tematy:: health
cardiovascular diseases
health behaviours
people aged 50+
Opis:: Introduction. The biggest threat to life are cardiovascular diseases which are a serious problem in Poland, Europe, and worldwide. Therefore, it has become important to have proper health behaviours which significantly eliminate the occurrence and development of cardiovascular diseases. Objective. The main aim of this study is to present factors that determine health behaviours of the 50+ population with cardiovascular diseases. Materials and metod. The study was carried out among 411 individuals aged over 50 with cardiovascular diseases. The method used was a diagnostic survey. The study involved an authors’ survey questionnaire and the Inventory of Health-Related Behaviours (IHB). A detailed statistical analysis was carried out in the R programme, version 3.5.1. Results. The most common disease in the study group was coronary heart disease – 63.75%. The majority of respondents showed (via Inventory of Health-Related Behaviour [IHB]) that the level of their health behaviours was moderate – 41.12%; the highest level of health behaviours in the study group were related to health practices, while a slightly lower level was observed in the area of positive mental attitude. Statistical significance was also found between the level of intensity of health behaviours and age, gender, BMI, place of residence, education, professional activity and marital status of the respondents. Conclusions. Anti-health behaviours were predominant among the respondents; significant demographic and social factors determining health behaviour were determined, such as age and gender; a high level of health behaviours was found in the group of women with higher education and correct body mass, living in cities and married.
Źródło:: Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 99-105
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 7.

Tytuł:: Gut microbiome as a biomarker of cardiometabolic disorders
Autorzy:: Gózd-Barszczewska, Anna
Kozioł-Montewka, Maria
Barszczewski, Piotr
Młodzińska, Agata
Humińska, Kinga
Powiązania:: https://bibliotekanauki.pl/articles/991115.pdf
Data publikacji:: 2017
Wydawca:: Instytut Medycyny Wsi
Tematy:: gut microbiota
atherosclerosis
lipid disorders
microbiome
cardiovascular diseases
Opis:: Introduction and objective. Cardiovascular diseases are the leading cause of death in Europe and worldwide. One of the most important risk factors for atherosclerosis are lipid metabolism disorders, in particular hipercholesterolaemia. The aim of the study was to determine the correlation between gut microbiota composition and atherosclerosis risk factors, so in order that it might be used as a biomarker for coronary artery disease diagnosis. Material and method. The study involved middle-aged men in eastern Poland with central obesity (n=20), subjects with atherosclerosis (n=15) and those with no cardiovascular diseases (n=5). The gut microbiota composition was determined using tag-encoded 16S rRNA gene using Illuminal MiSeq. Data were analyzed with the use of t-test. Results. Firmicutes (49.26%) and Bacteroidetes (44.46%) were the dominant Phyla in the middle-aged men in eastern Poland. Subjects with improper levels of total cholesterol were enriched in Prevotella (p=0.03) and decreased level of Clostridium (p=0.02). They also showed a falling tendency in Faecalibacterium (p=0.07). An upward trend was observed in Prevotella (p=0.07) in subjects with improper LDL-C values. Conclusions. The study showed that intestinal microbiome is likely to play a role in the pathogenesis of atherosclerosis through its role in lipid metabolism. Bacterial genera of particular importance were Prevotella, Bacteroides, Clostridium, Faecalibacterium. However, further studies involving larger groups of subjects are required to confirm these observations.
Źródło:: Annals of Agricultural and Environmental Medicine; 2017, 24, 3
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 8.

Tytuł:: Association between dietary patterns and cardiovascular risk factors in a selected population of Lower Silesia (PURE Study Poland)
Autorzy:: Czekajlo, A.
Różańska, D.
Zatońska, K.
Szuba, A.
Regulska-Ilow, B.
Powiązania:: https://bibliotekanauki.pl/articles/2081935.pdf
Data publikacji:: 2018
Wydawca:: Instytut Medycyny Wsi
Tematy:: risk factors
cardiovascular diseases
principal component analysis
dietary patterns
Opis:: Introduction. Dietary pattern analysis is used to describe the dietary habits of a selected population. In many studies, dietary patterns (DPs) have been associated with risk factors for cardiovascular disease (CVD). The aim of the study was to assess the association between dietary patterns identified in the population of Lower Silesia, Poland, with anthropometric and biochemical risk factors for CVD. Materials and method. The study group included 2,025 participants of the Prospective Urban Rural Epidemiological (PURE) Study. Dietary intake was evaluated based on data from the Food Frequency Questionnaire (FFQ). Dietary patterns were derived using principal component analysis (PCA). The relationship between DPs and body mass index (BMI), waist circumference, waist-hip ratio, blood pressure, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and fasting glucose level, was assessed. Results. Three dietary patterns identified in the study explained 35.6% of total variance. The ‘fruit, vegetables & dairy’ DP, characterized by a high intake of vegetables, fruits, nuts, seeds, raisins, milk and low-fat dairy, was associated with improved lipid profile and anthropometric measures, lower diastolic blood pressure and lower fasting glucose concentration. ‘Traditional’ and ‘fat & sugar’ DPs were unfavourably associated with most of the risk factors for CVD presented in this study. Conclusions. Dietary patterns identified in this study were differently related to selected anthropometric and biochemical risk factors for CVD. ‘Fruit, vegetables & dairy’ DP was favourably associated with the biochemical and anthropometric CVD risk factors, and was characterized by higher nutritional value in comparison with ‘traditional’ and ‘fat & sugar’ DPs.
Źródło:: Annals of Agricultural and Environmental Medicine; 2018, 25, 4; 635-641
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 9.

Tytuł:: Stress at intellectual work and cardiovascular diseases in women at non-mobility working age
Autorzy:: Raczkiewicz, D.
Bojar, I.
Wdowiak, A.
Rzeźnicki, A.
Krakowiak, J.
Powiązania:: https://bibliotekanauki.pl/articles/2085059.pdf
Data publikacji:: 2019
Wydawca:: Instytut Medycyny Wsi
Tematy:: stress at work
cardiovascular diseases
non-mobility working age
Opis:: Introduction and objective. Stress at the work place reduces efficiency, as well as increasing accidents and absences, which may cause various diseases, including cardiovascular diseases. The aim of the study is an analysis of the prevalence and causes of stress in intellectual work, and its correlation with the prevalence of cardiovascular diseases in women at non-mobility working age. Materials and method. The study was conducted in 2016–2017 in a group of 300 women aged 45–60 in non-manual employment. A questionnaire for subjective job evaluation was used. Logistic regression models for the occurrence of CVDs versus frequency of occurrence of individual causes of work stress among the respondents were estimated. Results. Women at non-mobility working age with non-manual employment are especially exposed to stress, half of them experience high level of stress at work, most often caused by social contacts and lack of rewards and support. Cardiovascular diseases were found in 26.5% of the women studied who were also significantly higher exposed to the occurrence of health hazards due to exposure to harmful factors, or due to an accident at work, changes in the workplace, the need to compete with others,and the need to perform the task despite the lack of appropriate material resources, compared with women without such diseases. Conclusions. The study revealed a high prevalence of occupational stress in non-manual employment, indicated its main causes that correlated with the alence of cardiovascular diseases. Actions are needed to reduce the level of stress in the work of women at non-mobility working age, to maintain their work ability and quality of life.
Źródło:: Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 456-461
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 10.

Tytuł:: Association between dietary glycaemic load and selected demographic, socio-economic and lifestyle factors in a group of adult Poles in Lower Silesia – results of the PURE Poland study
Autorzy:: Różańska, D.
Czekajło, A.
Zatońska, K.
Szuba, A.
Regulska-Ilow, B.
Powiązania:: https://bibliotekanauki.pl/articles/2085369.pdf
Data publikacji:: 2020
Wydawca:: Instytut Medycyny Wsi
Tematy:: glycaemic load
carbohydrates
cardiovascular disease
socio-economic status
lifestyle
Opis:: Introduction. There is a strong association between the occurrence of cardiovascular disease (CVD) and low socio-economic status (SES). It is interesting to consider whether high dietary glycaemic load (GL) is also associated with low SES or demographic factors. Objective. The aim of the study is to assess the relationship between dietary GL and demographic, socio-economic and lifestyle factors in a selected population of Polish adults in Lower Silesia. Materials and method. The study group consisted of 2,025 Polish adults (aged 35–70 years), enrolled in the 1st stage of the Prospective Urban Rural Epidemiological (PURE) study. Nutritional data were collected using a food frequency questionnaire (FFQ), which was developed and validated for the Polish population in Lower Silesia. The overall GL of each diet was computed as a sum of GL values of consumed foods. Results. Significantly higher GL and GL/1,000 kcal were observed in the diets of males compared to females and in the diets of rural compared to urban inhabitants. An adverse relationship between both GL and GL/1,000 kcal and level of education was found. The percentage of females, urban inhabitants, people with university education and not married decreased with quartiles of the overall dietary GL and GL/1,000 kcal. The percentage of former smokers, people who never used alcohol and people with low and moderate physical activity decreased with quartiles of GL and GL/1,000 kcal. Lower percentage of individuals aged 44–64 years was observed with quartiles of the overall dietary GL. Conclusions. Factors such as: male gender, rural place of residence, low level of education and smoking determine the group of people that is the most exposed on the effects of improper nutrition, according to the low quality and/or high amount of carbohydrates defined by GL and GL per 1,000 kcal.
Źródło:: Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 49-55
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 11.

Tytuł:: Fatal cardiovascular risk in Poland as determined via Internet
Autorzy:: Trzeciak, Bartosz
Gutknecht, Piotr
Molisz, Andrzej
Siebert, Janusz
Powiązania:: https://bibliotekanauki.pl/articles/989874.pdf
Data publikacji:: 2017
Wydawca:: Instytut Medycyny Wsi
Tematy:: cardiovascular risk factors
internet in healthcare
risk
‘ryzyko’ programme
score
Opis:: Introduction. Web information systems can serve as a diagnostic tool for Internet users and to support the epidemiological work of doctors and health care providers. As part of this work, a system for detecting and calculating cardiovascular risk has been created. Objectives. 1) Application of web-based risk assessment of cardiovascular death; 2) an attempt to evaluate the distribution of selected risk factors among the population of Polish Internet users; 3) implementation of the epidemiological imaging system of cardiovascular risk factors. Materials and method. The ‘Ryzyko’ programme (www.ryzyko.gumed.edu.pl.) available on the Internet. To assess cardiovascular death risk in a ten year period the algorithm of the SCORE project was used. 28,320 solutions of the algorithm have been registered. Results. Over 28,000 webpage visitors entered the required data and received the outcome. More than 71% of Internauts who entered the data received the recommendation for medical control. The result of the programme is a graphic presentation of the distribution of the calculated risk of death, based on previously gathered information given by the Internauts in particular provinces in Poland. Conclusion. Automatic monitoring of the incidence of cardiovascular risk factors in Poland provides information for epidemiological studies. The system meets the characteristics of diagnostic programmes that can assist epidemiologicbased and therapeutic decisions.
Źródło:: Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 12.

Tytuł:: Case of the PONS study
Autorzy:: Yusuf, S.
Powiązania:: https://bibliotekanauki.pl/articles/50463.pdf
Data publikacji:: 2011
Wydawca:: Instytut Medycyny Wsi
Tematy:: PONS project
Europe
Polska
health change
cardiovascular disease
mortality
PURE project
Źródło:: Annals of Agricultural and Environmental Medicine; 2011, 18, 2
1232-1966
Pojawia się w:: Annals of Agricultural and Environmental Medicine
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 13.

Tytuł:: Uric acid in hypertension - a marker of cardiovascular risk related to body composition
Autorzy:: Palkowska-Gozdzik, E.
Krzesinski, P.
Piotrowicz, K.
Stanczyk, A.
Gielerak, G.
Piechota, W.
Skrobowski, A.
Powiązania:: https://bibliotekanauki.pl/articles/3077.pdf
Data publikacji:: 2015
Wydawca:: Instytut Medycyny Wsi
Tematy:: uric acid
hypertension
cardiovascular risk
body composition
risk factor
obesity
hyperuricemia
Opis:: Introduction. Elevated uric acid (UA) is associated with arterial hypertension (AH), obesity, dyslipidemia and insulin resistance. However, its association with body components has not been previously investigated. Objective. The aim of this study was to evaluate the relationship between UA and cardiovascular risk factors, anthropometric parameters and body composition in patients with AH. Materials and method. In 138 patients with AH the following parameters were evaluated: UA, low and high density lipoproteins (LDL-C, HDL-C), triglycerides (TG), fasting glucose (FG), creatinine; body mass index (BMI), waist circumference (WC), fat mass (FM), fat free mass (FFM) and total body water (TBW). Results. Positive correlations were shown between UA and LDL-C (p=0.041), TG (p<0.001), FG (p=0.025) and creatinine (p<0.001) and negative between UA and HDL-C (p<0.001). Significant associations between UA and anthropometric parameters and body components, such as WC (p<0.001), BMI (p<0.001), FFM (p<0.001) and TBW (p<0.001), were also observed. In the multiple regression model, independent predictors of UA concentration were serum creatinine and TBW (R2=0.45; p<0.001). Conclusions. In patients with AH, uric acid was significantly related to cardiovascular risk factors, including obesity. However, the main anthropometric determinant of plasma UA concentration is FFM. The consideration of body composition in the interpretation of UA concentration appears to be justified, but the verification of this hypothesis requires further studies.
Źródło:: Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki