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Wyświetlanie 1-9 z 9
Tytuł:
Atherogenic lipid profile and health behaviours in women post-menopause working in agriculture
Autorzy:
Krakowiak, J.
Raczkiewicz, D.
Wdowiak, A.
Cichońska, D.
Bojar, I.
Powiązania:
https://bibliotekanauki.pl/articles/2085110.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
atherogenic lipid profile
health behaviours
post-menopausal women
Opis:
Introduction and objective. There is a significantly higher risk of lipid disorders occurrence, including atherogenic dyslipidemia in women after menopause than it is in general population. The aim of the work was to investigate the correlation between health behaviours and the occurrence of lipid disorders in women after menopause working in agriculture. Material and methods. The study was conducted in years 2015–2016 and included 843 post-menopausal women working in agriculture. The following were used: a questionnaire including socio-demographic data, laboratory lipid tests, inventory of health behaviours. The following were estimated: logistic regression models for serum lipids concentration versus frequency of health behaviours in the examined women. Results. Adverse lipid profile was found in over a half of post-menopausal women working in agriculture, whereas the frequency of health behaviours were estimated at the average level, although the frequency of correct eating habits and health practices was significantly lower than preventive behaviours and positive psychological attitudes. A correlation was found between the frequency of health behaviours and the occurrence of lipid disorders in women after menopause working in agriculture: more frequent health practices co-existed with the lower concentration of total cholesterol and a higher concentration of HDL-cholesterol, more frequent preventive behaviours co-existed with lower concentration of LDL-cholesterol. Women with higher concentration of triglycerides undertook pro-health practices relatively more often. Conclusions. The study revealed a high prevalence of lipid disorders in postmenopausal women working in agriculture. More effective health education programmes are necessary in the area of reduction the risk factors of CVD in the population of women working in agriculture.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 585-591
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gut microbiome as a biomarker of cardiometabolic disorders
Autorzy:
Gózd-Barszczewska, Anna
Kozioł-Montewka, Maria
Barszczewski, Piotr
Młodzińska, Agata
Humińska, Kinga
Powiązania:
https://bibliotekanauki.pl/articles/991115.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
gut microbiota
atherosclerosis
lipid disorders
microbiome
cardiovascular diseases
Opis:
Introduction and objective. Cardiovascular diseases are the leading cause of death in Europe and worldwide. One of the most important risk factors for atherosclerosis are lipid metabolism disorders, in particular hipercholesterolaemia. The aim of the study was to determine the correlation between gut microbiota composition and atherosclerosis risk factors, so in order that it might be used as a biomarker for coronary artery disease diagnosis. Material and method. The study involved middle-aged men in eastern Poland with central obesity (n=20), subjects with atherosclerosis (n=15) and those with no cardiovascular diseases (n=5). The gut microbiota composition was determined using tag-encoded 16S rRNA gene using Illuminal MiSeq. Data were analyzed with the use of t-test. Results. Firmicutes (49.26%) and Bacteroidetes (44.46%) were the dominant Phyla in the middle-aged men in eastern Poland. Subjects with improper levels of total cholesterol were enriched in Prevotella (p=0.03) and decreased level of Clostridium (p=0.02). They also showed a falling tendency in Faecalibacterium (p=0.07). An upward trend was observed in Prevotella (p=0.07) in subjects with improper LDL-C values. Conclusions. The study showed that intestinal microbiome is likely to play a role in the pathogenesis of atherosclerosis through its role in lipid metabolism. Bacterial genera of particular importance were Prevotella, Bacteroides, Clostridium, Faecalibacterium. However, further studies involving larger groups of subjects are required to confirm these observations.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Importance of early intervention in verapamil overdose – Case report and antidotes review
Autorzy:
Marzeda, P.
Drozd, M.
Tchorz, M.
Kisiel, K.
Powiązania:
https://bibliotekanauki.pl/articles/2098544.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Tematy:
verapamil
overdose
calcium channel blocker
lipid emulsion
antidote potential
Opis:
Introduction. Verapamil is a widely used cardiac drug. It belongs to the non-dihydropiridine subgroup of calcium channel blockers (CCBs), and is used mainly for the treatment of atrial dysrhythmias, hypertension or angina. In this article, we describe a case of poisoning with verapamil mixed with ethanol and review current treatment options. A 54-year-old female was admitted to the Toxicology Clinic by emergency medical services after ingesting sustained-release CCBs and ethanol in a suicidal attempt. The patient was successfully treated by administration of catecholamines and calcium, and the introduction of a high-dose insulin infusion (HDI). Conclusions. This case report emphasizes that even in severe poisoning, early and proper intervention may prevent circulatory breakdown. It also summarizes treatment options in patients after verapamil overdose. Along with decontamination, administration of catecholamines and correcting electrolyte abnormalities, the main options are HDI and lipid emulsion therapy (LET).
Źródło:
Journal of Pre-Clinical and Clinical Research; 2021, 15, 3; 142-147
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of dietary fat type on plasma lipid profile and leptin concentration in rats fed on high-sucrose diets
Autorzy:
Krawczynska, A.
Okreglicka, K.
Olczak, E.
Gromadzka-Ostrowska, J.
Powiązania:
https://bibliotekanauki.pl/articles/3460.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
dietary fat
fat type
plasma lipid profile
leptin concentration
rat
high sucrose diet
diet
linseed oil
grape seed oil
lipid profile
lard
human nutrition
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cognitive consequences of metabolic disorders
Autorzy:
Lopuszanska, U.
Cholewa, K.
Kozyra, M.
Powiązania:
https://bibliotekanauki.pl/articles/2098187.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Tematy:
metabolic disorder
obesity
overweight
lipid metabolism
hypertension
carbohydrate metabolism
cognitive function
Opis:
Introduction and objective. Metabolic disorders are associated with a number of negative health consequences. Therefore, the aim of this review was to define the relationships between overweight and obesity, lipid metabolism disorders, hypertension, disorders of carbohydrate metabolism, and cognitive functions. Abbreviated description of the state of knowledge. Metabolic disorders may be linked to the reduction of cognitive functions, such as memory, abstract reasoning, verbal fluency, attention and psychomotor speed. Obesity may lead to changes in the hippocampus, one of the main structures involved in learning and memory. The evidence reviewed suggests that obesity, by inducing inflammation, leads to the dysfunction of brain structures such as the frontal cortex and corpus callosum involved in plasticity processes and cognitive functions. In addition, obesity has been found to be associated with abnormalities in the white matter and glial cells in the brain, which may also cause reduction in processing speed. It is possible that there is a non-linear relationship between lipids and cognitive function moderated by age and the pro- inflammatory process. Disturbances in carbohydrate metabolism can also lead to cognitive impairment, such as: memory, verbal fluency or abstract reasoning. Conclusions. Metabolic disorders are associated with a higher risk of developing cognitive impairment. This association can be moderated by additional factors: lifestyle, oxidative stress, pro-inflammatory processes, genetic factors, age and education.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 139-144
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lipid pattern in middle-aged inhabitants of the Lower Silesian region of Poland. The PURE Poland sub-study
Autorzy:
Skoczynska, A.
Wojakowska, A.
Turczyn, B.
Zatonska, K.
Wolyniec, M.
Regulska-Ilow, B.
Ilow, R.
Szuba, A.
Zatonski, W.
Powiązania:
https://bibliotekanauki.pl/articles/50752.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Tematy:
lipid pattern
serum lipid
HDL-cholesterol
cholesterol
HDL-cholesterol fraction
middle-aged population
inhabitant
urban area
rural inhabitant
rural woman
urban woman
Lover Silesia
Silesian region
Polska
Opis:
Introduction. A decreased serum high density lipoprotein-cholesterol (HDL-C) is a strong predictor of cardiovascular risk. However, total HDL is a very dynamic, changeable fraction, and does not perform the function of atherosclerosis markers. In the presented study, the pattern of serum lipids, including HDL-C subclasses (HDL2- and HDL3-cholesterol), in a middleaged Polish Lower Silesia population was defined. Materials and method. A group of 746 males and 1,298 females, aged 35–70, were investigated. All subjects were participants in the PURE study. Mean serum lipid levels were determined for groups selected on the basis of gender, age, cigarette smoking, drinking alcohol and place of residence (urban/rural area). The data were analyzed using STATISTICA 6.0 PL. Results. In multiple linear regression models, age was the most important independent and consistent predictor of total cholesterol (TC) and LDL cholesterol (LDL-C). The prevalence of low HDL-C (threshold 40 mg/dL in males, 50 mg/dL in females) was 16.5% for males and 22.6% for females. This gender-conditioned difference in the prevalence of low HDL-C was greater in rural (20.0% vs. 30.9%, respectively, in males and females) in comparison to urban (14.4% vs. 17.1%) areas. The lipid pattern was significantly worse in rural than in urban females. Female rural inhabitants showed higher triglycerides (TG) and lower HDL cholesterol (total and contained in subclasses HDL2 and HDL3). Simultaneously, a higher BMI, higher percent of smokers and drinkers and lower age of smoking female rural inhabitants in comparison to urban females were estimated. In the total population, cigarette smoking or drinking alcohol were associated with significant increases in TC, LDL-C and TG, also with decreased HDL-C (smoking) or HDL2-C (drinking). Two-way analysis of variance showed the existence of interaction between these risk factors in their influence on HDL-C and HDL3-C. Conclusion. In the middle-aged population of the Lower Silesian region in Poland the place of residence (urban/rural area) had a significant impact on the lipid pattern. This pattern is more atherogenic in rural women than in urban women.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of lipids, lipoproteins and apolipoproteins concentrations in cord blood serum of newborns from rural and urban environments
Autorzy:
Pac-Kozuchowska, E
Powiązania:
https://bibliotekanauki.pl/articles/51130.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
cord blood serum
lipoprotein
risk factor
lipid
concentration
life style
rural environment
newborn
apolipoprotein
urban environment
Opis:
The purpose of the present study was to check the infl uence of rural and urban environments on some of the parameters of lipids metabolism in the cord blood serum in healthy newborns, as well as the evaluation of the concentration of lipids, lipoproteins and apolipoproteins in the cord blood serum with relation to risk factors of atherosclerosis in the family of the studied newborns. The study included 75 newborns (37 from rural areas and 38 from urban areas). Newborns weight and length were recorded at birth. On the basis of the family history taken from the mothers, the atherosclerosis risk factors were established in the families of the studied newborns. In all of the studied newborns, concentration of triglycerides, total cholesterol and LDL, VLDL and HDL cholesterol as well as of apolipoproteins (apo-AI, apo-B) in the cord blood serum sampled soon after birth were performed. No statistically signifi cant differences between the mean levels of triglycerides, total cholesterol and cholesterol of fractions: LDL, VLDL, HDL and apolipoproteins (apo-AI, apo-B) in the cord blood serum in the newborns from rural and urban areas were found. However, when analysing the concentration of parameters of lipid metabolism in cord blood serum in newborns with regard to gender, higher concentrations of total cholesterol, LDL cholesterol and apo-AI in female newborns from rural areas, and higher HDL cholesterol and apo-AI in female newborns from urban regions were confi rmed. When analysing the concentration of lipids and lipoproteins in cord blood serum in newborns from families with risk factors confi rmed as compared to the families without that risk, both in the rural and urban regions no signifi cant differences were confi rmed. The studies have not proved any signifi cant differences between the levels of lipids, lipoproteins and apolipoproteins in the cord blood serum in newborns from rural and urban areas.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers - a study in postmenopausal women
Autorzy:
Sagan, Dorota
Stępniak, Jan
Gesing, Adam
Lewiński, Andrzej
Karbownik-Lewińska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/987005.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
smoking
former-smokers
never-smokers
postmenopausal women
oxidative stress
lipid peroxidation
skin biophysical
characteristics
sebum
moisture
elasticity
Opis:
Introduction and objective. Protective antioxidative effects of melatonin have been repeatedly documented in experimental and clinical studies. One of the most spectacular exogenous prooxidative agents is cigarette smoking. The aim of the study was to evaluate the level of oxidative damage to membrane lipids (lipid peroxidation; LPO) in blood serum, and in epidermis exfoliated during microdermabrasion collected from former-smokers who were treated with melatonin. Materials and Method. The study was performed in postmenopausal women. Ninety (90) female volunteers, aged 46–67 years, were enrolled. Two major groups, i.e. never-smokers (n=44) and former-smokers (n=46), were divided into: Control, melatonin topical skin application, Restructurer (containing antioxidants) topical skin application, and melatonin oral treatment. Microdermabrasion was performed at point ‘0’, after 2 weeks, and after 4 weeks of treatment. The following parameters were measured: LPO in blood serum, LPO in epidermis exfoliated during microdermabrasion, and skin biophysical characteristics, such as sebum, moisture, elasticity, and pigmentation. Malondialdehyde+4-hydroxyalkenals level (LPO index) was measured spectrophotometrically. Results. Melatonin oral treatment significantly reversed the increased serum LPO level in former-smokers already after 2 weeks of treatment. In a univariate regression model, LPO blood level constituted the only independent factor negatively associated with melatonin oral treatment. After 4 weeks of treatment, melatonin given orally increased skin sebum, moisture and elasticity levels, and melatonin applied topically increased sebum level. Conclusion. Exogenous melatonin reverses the enhanced oxidative damage to membrane lipids and improves skin biophysical characteristics in former-smokers.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of phytoestrogen intake in the diet on lipid and sex hormone metabolism in menopausal women, and increased risk of breast cancer
Autorzy:
Kostrzewa-Tarnowska, A.
Czlapka-Matyasik, M.
Walkowiak, J.
Godlewski, D.
Powiązania:
https://bibliotekanauki.pl/articles/3279.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
phytoestrogen
intake
nutritional habit
diet
lipid
sex hormone
human metabolism
menopausal woman
woman
cancer risk
breast cancer
Opis:
Introduction and objective. Phytoestrogens are one of nutritional factors exhibiting a chemoprotective action, potentially reducing vasomotor symptoms as well as cancerous lesions. The study was ocused on an association between the consumption of phytoestrogens in the diet, blood serum cholesterol concentration and urinary estrogen metabolites levels. Materials and methods. The study was conducted on 55 women in the perimenopausal period, who were characterized by an increased risk of hormone-dependent cancer. Energy and nutritive value of food rations, and especially the level of phytoestrogen consumption in the diets in the examined population, were analyzed using the Wikt Pro computer programme. Estrogen metabolites (2OHE, 16α-OHE1) were determined from 24‑urine samples by the ELISA method. The EMR index was calculated. Plasma total cholesterol concentrations was measured. Results and conclusions. The population with a higher consumption of phytoestrogens and dietary fibre in the diet, at the simultaneous slight limitation of energy value of the food ration, is characterized by an improved blood serum cholesterol concentration and an appropriate estrogen metabolism towards a significant increase in the estrogen index for the cancer lesions in the mammary glands.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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