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Wyświetlanie 1-2 z 2
Tytuł:
Effects of sauna bathing on stress-related genes expression in athletes and non-athletes
Autorzy:
Żychowska, Małgorzata
Półrola, Paweł
Chruściński, Grzegorz
Zielińska, Jolanta
Góral-Półrola, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/989940.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
steam bath
gene expression
hspa1a
interleukins
athletes
Opis:
Introduction and objective. Heat stress induces the expression of genes encoding heat-shock proteins and immune response mediators. The aim of this study was to determine the differences in the expression of genes encoding heat-shock proteins 70 kDa and27 kDa, interleukin 6, interleukin 10and C-reactive protein, between athletes and non-athletes after sauna bathing. Materials and method. Athletes (n=9) and non-athletes (n=9) were exposed to a Finnish sauna twice during one session at a temperature of 98.2 °C and humidity of 10% ± 2%, with a 5 min break for cooling down under a shower. The groups did not differ in terms of age, height or body mass. Blood samples were taken before and after sauna exposure in order to assess gene expression, using reverse transcription polymerase chain reaction. Results. Differences were observed in leukocyte mRNA levels of tested genes between athletes and non-athletes. In the non-athlete group, all the tested genes were expressed at higher levels as a response to the same heat challenge. Conclusion. It appears that expression of stress-related genes induced by heat stress is dependent on the level of physical activity.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Differences in the expression of selected genes associated with cell stress response in a PTSD patient and in healthy individuals – a case study
Autorzy:
Rasmus, Anna
Półrola, Paweł
Góral-Półrola, Jolanta
Żychowska, Małgorzata
Mirski, Andrzej
Knapik, Henryk
Powiązania:
https://bibliotekanauki.pl/articles/986669.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
cell stress
ptsd patient
expression of selected genes
healthy individuals
Opis:
Objective. The aim of the study was determination of the level in expression genes associated with cell stress response in a patient with PTSD. Case study. A 57-year-old PTSD patient, A.P., was the subject of the study. Blood samples were taken from the ulnar vein to assess the relative expression of the tested genes in leukocytes via a quantitative reverse transcription polymerase chain reaction (qRT-PCR). Results. A considerably decreased level in the expression HSF-1, NF-kB, Hif-1 and IL6 m-RNA was observed in the patient when compared to the control group. A low expression in HSPA1A, HSPB1, IL10 and CRP m-RNA compared with the control group was also noted. Conclusion. It is possible that the lower level of transcriptional factors: HSF-1, NF-kB and Hif-1 as well as IL6 m-RNA may be associated with the effect of the PTSD patient’s treatment.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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