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Wyświetlanie 1-3 z 3
Tytuł:
Changing lifestyle and prevalence of malnutrition among settled pastoral Fulani children in Southwest Nigeria
Autorzy:
Ekpo, U F
Omotayo, A.M.
Dipeolu, M.A.
Powiązania:
https://bibliotekanauki.pl/articles/52162.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
malnutrition prevalence
malnutrition
nomad
life style
changing
food habit
Fulani population
Nigeria
child
Fulani child
Źródło:
Annals of Agricultural and Environmental Medicine; 2008, 15, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats
Autorzy:
Xun, ZM.
Xie, F.
Zhao, PX.
Liu, MY.
Li, ZY.
Song, JM.
Kong, XM.
Ma, XM.
Li, XY.
Powiązania:
https://bibliotekanauki.pl/articles/2085965.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
oxidative stress
hepatotoxicity
chlorpyrifos
molecular hydrogen
mitochondrial pathway
Opis:
Introduction. Chlorpyrifos (CPF) is a organophosphate insecticide widely used in agriculture with attendant adverse health outcomes. Chronic exposure to CPF induces oxidative stress and elicits harmful effects, including hepatic dysfunction. Molecular hydrogen has been identified as a novel antioxidant which could selectively scavenge hydroxyl radicals. Objective. The aim of this study was to determine whether the intake of hydrogen-rich water (HRW) could protect rats from hepatotoxicity caused by sub-chronic exposure to CPF. Materials and method. Rats were treated with hydrogen-rich water by oral intake for 8 weeks. Biochemical indicators of liver function, SOD and CAT activity, GSH and MDA levels were determined by the spectrophotometric method. Liver cell damage induced by CPF was evaluated by histopathological and electron microscopy analysis. PCR array analysis was performed to investigated the effects of molecular hydrogen on the regulation of oxidative stress related genes. Results. Both the hepatic function tests and histopathological analysis showed that the liver damage induced by CPF could be ameliorated by HRW intake. HRW intake also attenuated CPF induced oxidative stress, as evidenced by restored SOD activities and MDA levels. The results of PCR Array identified 12 oxidative stress-related genes differentially expressed after CPF exposure, 8 of chich, including the mitochondrial Sod2 gene, were significantly attenuated by HRW intake. The electron microscopy results indicated that the mitochondrial damage caused by CPF was alleviated after HRW treatment. Conclusions. The results obtained suggest that HRW intake can protect rats from CPF induced hepatotoxicity, and the oxidative stress signaling and the mitochondrial pathway may be involved in the protection of molecular hydrogen.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 368-373
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Serological and molecular evidence of hepadnavirus infection in swine
Autorzy:
Vieira, Y.R.
Silva, M.F.M.
Santos, D.R.L.
Vieira, A.A.
Ciacci-Zanella, J.R.
Barquero, G.
do Lago, B.V.
Gomes, S.A.
Pinto, M.A.
de Paula, V.S.
Powiązania:
https://bibliotekanauki.pl/articles/989989.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
diagnostic
hepadnavirus
swine
Opis:
Introduction and objective. Recently, investigations in a swine herd identified evidence of the existence of a novel member of the Hepadnavirus family endemic in swine. The aim of this study was to investigate the serological and molecular markers of Hepadnavirus circulation in Brazilian domestic swine and wild boar herds, and to evaluate the identity with HBV and other Hepadnaviruses reported previously. Materials and methods. For the study, 376 swine were screened for hepatitis B virus serological markers. Analyses were performed in serum samples using commercial enzyme-linked immunosorbent assay (ELISA) kits (DiaSorin®) for anti-HBc, HBsAg and anti-HBs. Reactive and undetermined swine serum samples were selected to perform DNA viral extraction (QIAamp DNA Mini Kit, Qiagen®), partial genome amplification and genome sequencing. Results. From 376 swine samples analysed, 28 (7.45%) were reactive to anti-HBc, 3 (0.80%) to HBsAg and 6 (1.6%) to anti-HBs. Besides, more 17 (4.52%) swine samples analyzed were classified in the grey zone of the EIA test to anti-HBc and 2 (0.53%) to HBsAg. From 49 samples molecularly analyzed after serological trial, 4 samples showed a positive result for the qualitative PCR for Hepadnavirus. Phylogenetic reconstruction using partial genome sequencing (360 bp) of 3 samples showed similarity with HBV with 90.8–96.3% of identity. Conclusions. Serological and molecular data showed evidence of the circulation of a virus similar to hepatitis B virus in swine.
Źródło:
Annals of Agricultural and Environmental Medicine; 2015, 22, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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