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Tytuł:
Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions
Autorzy:
Borowicz, K.K.
Piskorska, B.
Stepniak, B.
Czuczwar, S.J.
Powiązania:
https://bibliotekanauki.pl/articles/50030.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Opis:
Depression is becoming a growing problem in rural areas. This psychiatric disorder often accompanies epilepsy. The aim of this study was to assess the influence of fluoxetine (FXT), a commonly used antidepressant, on the protective action of two conventional antiepileptic drugs: ethosuximide (ETX) and valproate (VPA), against pentylenetetrazole (PTZ)-induced convulsions in mice. Motor coordination and long-term memory deficits induced by FXT, antiepileptic drugs alone and in combinations with FXT were assessed in the chimney test and passive-avoidance task, respectively. Brain concentrations of ETX and VPA were measured by immunofluorescence. Obtained results indicate that FXT at the dose of 15 mg/kg (ip, 30 min before the test) significantly increased the threshold for clonic convulsions. The antidepressant drug at lower doses remained ineffective in this respect. Moreover, FXT at the highest subprotective dose (10 mg/kg, ip) markedly enhanced the anticonvulsant effects of VPA, but not of ETX, against PTZ-induced seizures. The interaction between FXT and VPA seems to be pharmacodynamic because the antidepressant drug did not alter the brain concentration of VPA. With regard to adverse effects, FXT, VPA, ETX, and the combinations of FXT with antiepileptic drugs, did not impair motor coordination and long-term memory in mice. In conclusion, the combination of FXT with VPA may be advantageous in the treatment of myoclonic epilepsy, and therefore it should be recommended for further study in clinical conditions.
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Satisfaction with interpersonal relations among employees of State Forests in Poland
Autorzy:
Lachowski, S.
Florek-Luszczki, M.
Zagórski, J.
Lachowska, B.
Powiązania:
https://bibliotekanauki.pl/articles/2081659.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
job satisfaction
interpersonal relationships
forestry workers
determinants of satisfaction
Opis:
Introduction and objective. The aim of this study is to assess the interpersonal relations of employees of State Forests in Poland, as well as to indicate the factors related to the level of satisfaction with the relations among people employed in similar positions, and relations with superiors. Materials and method. The issues investigated were developed based on research conducted between 2014–2015 among employees of State Forests in Poland. In each of the 9 forest districts selected, 25 people were selected for testing from 3 groups of employees: foresters, deputy foresters and supervisors, together with administrative staff. Altogether, 399 people took part in the study conducted by means of a questionnaire. Results. The study showed that the overall level of satisfaction with interpersonal relations among employees of State Forests in Poland is high. Analysis indicated that the demographic characteristics of respondents, such as age, gender or place of residence, had no significant influence on satisfaction with interpersonal relations in the workplace. However, the level of satisfaction with interpersonal relations was positively affected by a high level of overall job satisfaction and satisfaction with remuneration. Decrease in the level of satisfaction was influenced by the accumulation of stressful life events and employment in administration. Conclusions. Satisfaction with interpersonal relationships in the workplace is an important indicator of employee mental health. Studies have shown the need to broaden the scope of research into the variables that determine the character and personality of an employee.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 300-306
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular and serological diagnosis of Borrellia burgdorferi infection among patients with diagnosed erythema migrans
Autorzy:
Kondrusik, M
Grygorczuk, S.
Skotarczak, B.
Wodecka, B.
Rymaszewska, A.
Pancewicz, S.
Zajkowska, J.
Swierzbinska, R.
Hermanowska-Szpakowicz, T.
Powiązania:
https://bibliotekanauki.pl/articles/51856.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Tematy:
human disease
erythema migrans phase
patient
diagnosis
ELISA test
polymerase chain reaction
serological diagnosis
Borrelia burgdorferi
borreliosis
Opis:
The aim of the study was to assess the frequency of Borrelia burgdorferi DNA detection in the blood and urine of patients diagnosed with erythema migrans, and compare the results of PCR-based methods with ELISA methodology. The latter was used to detect serum antibodies against Borrelia burgdorferi of the IgM and IgG classes, before and after antibiotic therapy. The study included 86 patients hospitalized in the Department of Infectious Diseases and Neuroinfections in the Medical Academy in Białystok, diagnosed with the erythema migrans phase of Lyme borreliosis. Examinations were carried out twice: the fi rst at the moment of diagnosis (Trial 1), the second after 4 weeks of antibiotic therapy. The study showed that antibiotic therapy in the early phase of borreliosis does not decrease the sensitivity of PCR and that after 4 weeks of therapy (Trial 2), spirochete DNA is still detectable in most patients (45/86). There was no correlation between detectability of spirochete DNA and the presence of antibodies against B. burgdorferi s.l. (assessed by ELISA) during the course of erythema migrans. The largest percentage of positive results in the detection of B. burgdorferi s.l. DNA was observed in patients who simultaneously possessed IgM and IgG antibodies against B. burgdorferi, while the lowest percentage of PCR positive results was among patients with only IgM antibodies.
Źródło:
Annals of Agricultural and Environmental Medicine; 2007, 14, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vitamin D and upper respiratory tract infections in young active males exposed to cold environments
Autorzy:
Orysiak, J.
Fitzgerald, J.S.
Malczewska-Lenczowska, J.
Witek, K.
Gajewski, J.
Zembron-Lacny, A.
Morawin, B.
Sitkowski, D.
Powiązania:
https://bibliotekanauki.pl/articles/28762740.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2021, 28, 3; 446-451
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Postpartum adiponectin changes in women with gestational diabetes
Autorzy:
Martyjaszek-Matuszek, B.
Lenart-Lipinska, M.
Kowalczyk-Boltuc, J.
Wozniak, S.
Paszkowski, T.
Powiązania:
https://bibliotekanauki.pl/articles/51076.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Postnatal inversion of the uterus – management in specific cases
Autorzy:
Michalska, M.
Bojar, I.
Borycki, J.
Zięba, B.
Brandl, S.
Kołaciński, R.
Samulak, D.
Powiązania:
https://bibliotekanauki.pl/articles/28762986.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 4; 717-720
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of SARS-CoV-2 infection on out-ofhospital cardiac arrest outcomes - systematic review and meta-analysis
Autorzy:
Krawczyk, A.
Szarpak, L.
Bragazzi, N.L.
Cander, B.
Feduniw, S.
Pruc, M.
Luszczki, J.
Chmielewski, J.
Kowalczyk, M.
Powiązania:
https://bibliotekanauki.pl/articles/28762637.pdf
Data publikacji:
2023
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2023, 30, 2; 369-375
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Dilated cardiomyopathy in the course of thrombophilia
Autorzy:
Prystupa, A.
Lachowska-Kotowska, P.
Makaruk, B.
Ignatowicz, A.
Szkutnicki, S.
Mosiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/3343.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Air-spore in Cartagena, Spain: Viable and non-viable sampling methods
Autorzy:
Elvira-Rendueles, B.
Moreno, J.
Garcia-Sanchez, A.
Vergara, N.
Martinez-Garcia, M.J.
Moreno-Grau, S.
Powiązania:
https://bibliotekanauki.pl/articles/51349.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of menopausal hormone therapy on the levels of magnesium, zinc, lead and cadmium in post-menopausal women
Autorzy:
Jurczak, A.
Brodowski, J.
Grochans, E.
Karakiewicz, B.
Szkup-Jablonska, M.
Wieder-Huszla, S.
Mroczek, B.
Wloszczak-Szubzda, A.
Grzywacz, A.
Powiązania:
https://bibliotekanauki.pl/articles/50553.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction and objective: The level of trace elements is extremely important for the maintenance of normal functioning of the human body. The risk of disturbance of their balance increases especially dynamically during the period of menopause. The objective of the study was the effect of MHT on the levels of bioelements (Mg and Zn) in blood plasma, and toxic metals (Pb and Cd) in the whole blood in postmenopausal women. Materials and methods: The study covered 323 women at postmenopausal age from the population of the West Pomeranian Region, in whom the levels of Mg, Zn, Pb and Cd were determined. The women were divided into two groups: study and control. The study group were 152 women who used menopausal hormone therapy (MHT). The control group were 171 women who did not use MHT, and had had their final menstrual period at least one year prior to inclusion in the study. The mean age of the women examined was 56±5. Results: Significantly higher levels of the bioelements Mg, Zn were observed in women who used MHT, compared to the control group (p<0.05). The concentration of Pb in whole blood was significantly lower in the study than the control group: 16.09±7.33 μg/l and 20.18±9.01 μg/l, respectively. An elevated level of Cd in whole blood was found in both groups of women: 0.9±1.03 μg/l and 0.8±1.1 μg/l, respectively. It was noted that women who used MHT more frequently declared the presence of climacteric symptoms (p<0.05). Conclusions: 1) Higher levels of Mg and Zn were found in blood plasma of women who used MHT. 2) The mean concentration of Cd in the blood of women in both groups was similar. 3) In women who use MHT the level of Pb in whole blood was lower, compared to the rest of the women.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interleukin 2 as a potential cancer marker in patients after kidney transplantation
Autorzy:
Witkowska, A.
Zywiec, J.
Strozik, A.
Gorczynska-Kosiorz, S.
Trautsolt, W.
Strzalka-Mrozik, B.
Kimsa, M.
Owczarek, A.
Stepien, B.
Mazurek, U.
Grzeszczak, W.
Gumprecht, J.
Powiązania:
https://bibliotekanauki.pl/articles/50550.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2015, 22, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Badanie ultrasonograficzne jamy brzusznej w diagnostyce guzów jelita grubego - opis przypadku
Ultrasonography of abdominal cavity in the diagnostics of tumours of the large intestine - case report
Autorzy:
Prystupa, A.
Makaruk, B.
Milaniuk, S.
Baraniak, J.
Kurys-Denis, E.
Chan, T.-Y.
Prystupa, T.
Krupski, W.
Mosiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/4034.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Medycyna Ogólna i Nauki o Zdrowiu; 2014, 20(49), 4
2083-4543
Pojawia się w:
Medycyna Ogólna i Nauki o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 25

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