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Tytuł:
Determination of benzo(a)pyrene content in PM10 using regression methods
Określanie zawartości benzo(a)pirenu w PM10 za pomocą metod regresyjnych
Autorzy:
Gębicki, Jacek
Ludkiewicz, Tomasz
Namieśnik, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1177516.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
"PM10 dust"
"benzo(a)pyrene B(a)P"
"coefficient of determination"
"multidimensional linear regression"
Opis:
The paper presents an attempt of application of multidimensional linear regression to estimation of an empirical model describing the factors influencing on B(a)P content in suspended dust PM10 in Olsztyn and Elbląg city regions between 2010 and 2013. During this period annual average concentration of B(a)P in PM10 exceeded the admissible level 1.5-3 times. Conducted investigations confirm that the reasons of B(a)P concentration increase are low-efficiency individual home heat stations or low-temperature heat sources, which are responsible for so-called low emission during heating period. Dependences between the following quantities were analysed: concentration of PM10 dust in air, air temperature, wind velocity, air humidity. A measure of model fitting to actual B(a)P concentration in PM10 was the coefficient of determination of the model. Application of multidimensional linear regression yielded the equations characterized by high values of the coefficient of determination of the model, especially during heating season. This parameter ranged from 0.54 to 0.80 during the analyzed period.
W pracy przedstawiono próbę zastosowania wielowymiarowej regresji liniowej do szacowania empirycznego modelu opisującego czynniki wpływające na zawartość B(a)P w pyle zawieszonym PM10 na terenie Olsztyna i Elbląga w latach 2010-2013. W tym okresie średnioroczne stężenie B(a)P w pyle PM10 ponad 1,5-3 krotnie przewyższało poziom docelowy. Przeprowadzone badania potwierdziły, że główną przyczyną wzrostu stężenia jest nieefektywność domowych kotłowni czy niskotemperaturowych źródeł ciepła, które odpowiadają za tzw. niską emisję w okresie grzewczym. Analizie poddano wzajemne zależności: stężenia pyłu PM10 w powietrzu, temperaturę powietrza, prędkość wiatru, kierunek wiatru, wilgotność powietrza. Miarą dopasowania modelu do rzeczywistego stężenia B(a)P w PM10 był współczynnik determinacji modelu. Zastosowanie wielowymiarowej regresji liniowej, przyczyniło się do opracowania równań charakteryzujących się wysokimi wartościami współczynnika determinacji modelu zwłaszcza w okresie grzewczym. Parametr ten w analizowanym okresie był na poziomie od 0,54 do 0,80.
Źródło:
Medycyna Środowiskowa - Environmental Medicine; 2015, 18, 4; 23-26
1505-7054
2084-6312
Pojawia się w:
Medycyna Środowiskowa - Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Retrospective study of injury rates among children and adults in the Lublin Region of Poland
Autorzy:
Domzal-Drzewicka, R.
Saracen, A.
Rzaca, M.
Wegorowski, P.
Stanislawek, A.
Michalak, B.P.
Powiązania:
https://bibliotekanauki.pl/articles/51286.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2016, 23, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Research into analgesic effect of ondansetron in persistent pain model in rats with central noradrenergic system lesion
Autorzy:
Roczniak, W.
Oswiecimska, J.M.
Brodziak-Dopierala, B.
Cipora, E.
Nowak, P.G.
Babuska-Roczniak, M.
Powiązania:
https://bibliotekanauki.pl/articles/3631.pdf
Data publikacji:
2015
Wydawca:
Instytut Medycyny Wsi
Tematy:
analgesic effect
ondansetron
persistent pain model
rat
central noradrenergic system
Opis:
Introduction. Many known substances affecting the serotoninergic system induce definite physiological effects, including those which are therapeutic. For instance, the enhanced serotoninergic transmission due to decreased functions of autoreceptors and increased inhibitory functions of postsynaptic 5-HT1A is associated with antidepressant effect. The central serotoninergic system takes part in the regulation of many bodily functions, such as sleep, wakefulness, blood pressure, pain perception or sexual behaviours. Moreover, it is involved in the pathogenesis of depression, anxiety, addictions, migraine and other headaches. In pain therapy, not only typical analgesics are used, but also substances without obvious analgesic effect, thus allowing potential pharmacological modulation of analgesic activity in the treatment of pain. Objective. The aim of the study was to determine whether a chemical lesion to the central noradrenergic system at an early stage of individual development alters reactivity of 5-HT3 receptors in adult rats. Materials and method. The study used newborn and adult Wistar rats aged 8–10 weeks. Behavioural tests (writhing test, formalin assay) were used to assess the analgesic action of ondansetron as a 5-HT3 receptor antagonist. Results. The analgesic effect of ondansetron (1.0 mg/kg b.w., i.p.) in the writhing test was weak and short. Pain intensity score after ondansetron injection (1.0 mg/kg b.w., i.p) was 2–3 points and did not differ significantly between the study groups. Conclusions. Damage to the central noradrenergic system at an early stage of individual development has no effect on the antinociceptive effects of the serotonin (5-HT3) receptor antagonist, ondansetron, in the persistent pain model.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
MicroRNA-26a-5p: multiple functions, multiple possibilities – a mini-review
Autorzy:
Zapolnik, P.
Zapolnik, B.
Powiązania:
https://bibliotekanauki.pl/articles/2098206.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
microRNA
molecular target
therapy
nucleotide
miR-26a-5p
therapeutic effect
Opis:
Introduction. MicroRNA are small RNA molecules about 22 nucleotides long that do not encode proteins. Their function is to change the expression of proteins by attaching to their mRNA. They participate in various biological processes and pathogenesis of many diseases, including cancer. MicroRNA-26a-5p (miR-26a-5p) takes part in developing many disease entities and may become a potential therapeutic agent. Objective. The article aims to present the current knowledge on miR-26a-5p and consider the possible therapeutic use of this molecule. State of knowledge. Many studies on cell lines and model organisms indicate the suppressive function of miR-26a-5p in such neoplasms as breast cancer, pancreatic cancer, prostate cancer, thyroid cancer, or acute myeloid leukemia. In turn, in osteosarcoma cells, miR-26a-5p has an oncogenic character. miR-26a-5p is also associated with other diseases. Many authors have shown that this molecule is related to such entities as rheumatoid arthritis, osteoarthritis, preeclampsia, myocardial injury, or diabetic nephropathy. Conclusions. Understanding the functions of miR-26a-5p and its participation in human diseases’ pathogenesis gives the possibility of the therapeutic use of this molecule in the future. However, knowledge of this subject is still limited. Further research to assess the efficacy and safety of the therapeutic use of miR-26a-5p is mandatory.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 130-133
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The efficacy of cognitive rehabilitation with RehaCom programme in schizophrenia patients. The role of selected genetic polymorphisms in successful cognitive rehabilitation
Autorzy:
Mak, M.
Samochowiec, J.
Tybura, P.
Bienkowski, P.
Karakiewicz, B.
Zaremba-Pechmann, L.
Mroczek, B.
Powiązania:
https://bibliotekanauki.pl/articles/51211.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction. Schizophrenic patients present cognitive dysfunctions which are regarded to be one of endophenotypical markers predisposing to schizophrenia. Currently, schizophrenia can be treated as a neurodegenerative and neurodeveloping disease with genetic background. Objective. Assessment of the possible positive effect of neuropsychological rehabilitation in schizophrenia, in patients presenting cognitive dysfunctions. An additional aim was to verify the hypothesis that some genetic polymorphisms can be a prognostic factor for success in neuropsychological rehabilitation. Material and methods. 41 participants and 40 control subjects were randomly selected. Both groups had the diagnosis of paranoid schizophrenia. Cognitive functions were checked with the Wisconsin Card Sorting Test, Trail Making Test, and Stroop Test at the beginning and end of the experiment. In the research group, each patient trained with the rehabilitation programme RehaCom, whereas the control group did not receive such training. Genes COMT rs4680 and BDNF rs6265 were analysed in the genetic part of study. Results. RehaCom procedures appear to be useful in the neuropsychological rehabilitation of cognitive dysfunctions in patients diagnosed with schizophrenia. The research group showed a moderate improvement in the training programmes. Analysis of parameters obtained in the neuropsychological tests showed a slight improvement in both groups. At the present time, analysis of the polymorphisms of genes cannot be treated as a prognostic factor for the success of neuropsychological rehabilitation because statistical analyses showed few dependences with little statistical significance. Conclusions. Cognitive rehabilitation produces moderate improvement in cognitive functioning.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Severity of work in opinions of rural women living in the Bieszczady region of south-eastern Poland
Autorzy:
Pawlak, H.
Petkowicz, B.
Maniak, B.
Kuna-Broniowska, I.
Petkowicz, J.
Buczaj, A.
Maksym, P.
Nowakowicz-Debek, B.
Gawda, P.
Powiązania:
https://bibliotekanauki.pl/articles/2081600.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
work load
position at work
rural women
Opis:
Objective. The objective of the study was recognition of the opinions of rural women living in the Bieszczady region of south-eastern Poland, concerning their perception of the degree of severity of work. The study was conducted among the inhabitants of the Cisna commune. Materials and method. The basic research instrument was a questionnaire form containing 15 items. The study covered 101 women living in the Cisna commune in the Bieszczady. The self-reported degree of work load on a farm was analyzed among women who were occupationally active, and those who were not occupationally active. The effect of assistance from family members on the severity of work perceived by women was considered. Results. The women in the study focused on agro-tourism, a few of them were engaged in agricultural work and the majority worked in household gardens. The study showed that occupationally active women work considerably longer, on average, and are the most loaded, compared to those not engaged in occupational activity. The mean daily time devoted to duties on a farm did not significantly differ between occupationally active and non-active women, and amounted to 380 and 320 minutes, respectively. The majority of women who were non-active occupationally evaluated their household chores as the highest work load. In turn, the women who undertook occupational activity assessed them as most burdensome, despite great help from their family. The body positions assumed while performing field work were: standing, standing-bent-over, and walking. The mean evaluations of work load while standing and standing-bent-over did not significantly differ, but affected the work load among women who, however, could not assess the severity of their work resulting from the body position assumed.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 1; 145-150
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Helicobacter pylori and rheumatoid arthritis
Autorzy:
Graff, L.B.
Andersen, L.P.
Gernow, A.
Bremmelgaard, A.
Bonnevie, O.
Bondesen, S.
Danneskiold-Samsoe, B.
Bartels, E.M.
Powiązania:
https://bibliotekanauki.pl/articles/3688.pdf
Data publikacji:
2007
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2007, 01, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Psychiatric symptomatology and personality in a population of primary care patients
Autorzy:
Biala, M.
Piotrowski, P.
Kurpas, D.
Kiejna, A.
Steciwko, A.
Stanczykiewicz, B.
Mroczek, B.
Nitsch-Osuch, A.
Karakiewicz, B.
Bielska, D.
Marciniak, D.
Powiązania:
https://bibliotekanauki.pl/articles/50402.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exposure to environmental factors and relationship to allergic rhinitis and/or asthma
Autorzy:
Azalim, S.P.
Camargos, P.
Alves, A.L.
Senna, M.I.B.
Sakurai, E.
Schwabe Keller, W.
Powiązania:
https://bibliotekanauki.pl/articles/50599.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2014, 21, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Urban vs. rural patients. Differences in stage and overall survival among patients treated surgically for lung cancer
Autorzy:
Rybojad, P.
Dluski, D.
Rybojad, B.
Kedra, M.
Sawicki, M.
Skoczylas, P.
Tabarkiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/49882.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
Introduction. Besides the undoubted influence of risk factors on morbidity and survival time, there are also other environmental factors, such as awareness of the prevalence of risk factors and the availability of modern diagnosis and treatment methods. Objective. To evaluate differences in lung cancer 5-year overall survival rates between urban and rural patients hospitalized in the Department of Thoracic Surgery of the Medical University in Lublin, Poland, and possible influence of several risk factors on these rates. Materials and methods. The analysis was based on 125 lung cancer patients who underwent surgical procedures in years 2006-2007 and who agreed to take part in the survey. The study aimed at recognition of the health situation and selected demographic traits of people who had been treated surgically for lung cancer. The differences were evaluated between rural and urban inhabitants in gender, age, lung function, smoking habits, exposure to risk factors at work, family history of cancer, staging of the disease, histological type of cancer, post-surgical treatment, and their possible influence on overall survival. Results. The results showed that the only noted differences between urban and rural population were in tobacco smoking and lung function. Survival rates were very similar and did not differ from the European average. Conclusions. The assumption that Polish rural patients are presenting with later cancer stages at the time of diagnosis, and have worse chances for survival, has become invalid in modern times.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Global Adult Tobacco Survey (GATS) in Poland 2009-2010 – study strengths, limitations and lessons learned
Autorzy:
Kaleta, D.
Usidame, B.
Bilinski, P.
Raciborski, F.
Samolinski, B.
Wojtyla, A.
Fronczak, A.
Powiązania:
https://bibliotekanauki.pl/articles/51879.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł

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