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    Wyświetlanie 1-5 z 5
    Tytuł:
    The incidence of lidocaine allergy in dentists: an evaluation of 100 general dental practitioners
    Autorzy:
    Janas-Naze, Anna
    Osica, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/2161981.pdf
    Data publikacji:
    2019-06-14
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    allergy
    dentists
    anaphylaxis
    lidocaine
    hypersensitivity
    local anaesthetics
    Opis:
    Objectives Local anesthetics are some of the most common drugs used in dentistry and about 6 million people daily around the world are subjected to their effect in procedures performed by a similar number of dentists who, in turn, are usually not aware of the fact of being allergic to this group of medications. Assuming that dentists are also patients, and that in their daily practice the contact with the allergen is very frequent, it is essential to assess the incidence of allergy to lidocaine in general dental practitioners. Material and Methods The authors evaluated a group of 100 general dental practitioners in whom adverse reactions similar to anaphylaxis occurred after local anesthesia. The study included individuals who, in their thorough medical history, had experienced episodes of such reactions regarding the skin, airways, gastrointestinal tract and other areas. Results The relations between type I hypersensitivity and certain symptoms, time from exposure to their appearance, as well as time from the last episode were investigated. Allergy to lidocaine was detected in 17 subjects – type I hypersensitivity was diagnosed in 13 cases (skin prick test – 7; intradermic test – 6) and 4 subjects had IgE-independent allergy (patch test). In the group where type I hypersensitivity was detected, urticaria, angioedema and rhinitis were indicated as inclusion criteria more often than among other subjects. According to the results, the occurrence of angioedema increased the risk of detection of type I hypersensitivity 68.8 times, and 1 year longer period from the last episode decreased this risk by circa 55%. Conclusions The most important, from the clinical practice point of view, was to show the relation between the medical history indicating the anaphylactic nature of the lidocaine intolerance, and an allergy confirmed by skin tests. Int J Occup Med Environ Health. 2019;32(3):333–9
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 3; 333-339
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of upper respiratory allergy on acute respiratory response to ambient air pollution during physical exercise
    Autorzy:
    Kocot, Krzysztof
    Powiązania:
    https://bibliotekanauki.pl/articles/2116537.pdf
    Data publikacji:
    2020-09-17
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    air pollution
    exercise
    spirometry
    particulate matter
    nitric oxide
    hypersensitivity
    Opis:
    ObjectivesAmbient air pollution is related to adverse respiratory effects. Because of a popular habit of recreational physical activity, the effects of exposure to increased levels of air pollution attract increasing attention. It remains unclear whether the allergy status has an impact on acute responses to air pollution exposure during brief exercise in young adults. The aim of the study was to determine if acute respiratory responses to ambient air pollution during physical exercise differ between young subjects with and without a history of upper respiratory allergy.Material and MethodsOverall, 41 young males with (N = 15, 36.6%) and without allergy (N = 26, 63.4%) performed short moderate-intensive cycle-ergometer sessions in winter air pollution exposure conditions. Associations were analyzed between environmental conditions and acute physiological changes in spirometry, fractioned exhaled nitric oxide (FeNO) levels, blood pressure and pulse oximetry.ResultsNo associations between air pollution concentrations and changes in forced vital capacity, forced expiratory volume in 1 s and the Tiffeneau index were found. In the subjects without allergy, the increased air pollution concentrations recorded during exercise were associated with a post-exercise increase/a smaller decrease in FeNO (SO2: Spearman’s ρ = 0.44, NOx: ρ = 0.51, and particulate matter [PM] levels – PM10: ρ = 0.51, PM2.5: ρ = 0.52). This effect was not observed in the subjects with allergy.ConclusionsUpper-respiratory allergy may be a modifying factor in human response to air pollution during exercise. Exposure to air pollution during brief moderate-intensive exercise did not have any acute negative impact on respiratory and cardiovascular function in young males. However, in the case of FeNO, subclinical post-exercise changes related to air pollution were observed in volunteers without allergy.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2020, 33, 5; 649-660
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Occupational allergy to horse allergens: More than exposure to horses!
    Autorzy:
    Liccardi, Gennaro
    Calzetta, Luigino
    Sapio, Carmine
    Rogliani, Paola
    Powiązania:
    https://bibliotekanauki.pl/articles/2168363.pdf
    Data publikacji:
    2016-07-07
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    bronchial asthma
    horse
    horse allergy
    hypersensitivity
    occupational allergy
    occupational asthma
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2016, 29, 5; 721-723
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dont we overestimate drug allergies in children?
    Autorzy:
    Podlecka, Daniela
    Jerzyńska, Joanna
    Brzozowska, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/21375381.pdf
    Data publikacji:
    2023-11-27
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    hypersensitivity
    drug allergy
    children
    local anesthetics
    nonsteroidal anti-inflammatory drugs
    β-lactam antibiotics
    Opis:
    Objectives On average about 10% of parents report hypersensitivity to at least 1 drug in their children. After diagnosis process a few of these reactions are being confirmed as drug hypersensitivity reactions. The aim of the study was to assess the real-life prevalence of drug hypersensitivity in children based on drug provocation tests. Material and Methods The authors included 113 children, aged 4–18 years, referred to Pediatrics and Allergy Clinic in Łódź, Poland, due to incidence of adverse reaction during treatment. Medical history regarding allergies to drugs was taken in accordance to the form developed by the United States Food and Drug Administration Adverse Event Reporting System. Skin prick tests, intradermal test and drug provocation test were performed in all patients. Results In all 113 patients suspected of drug allergy, after all diagnostic procedures, the authors proved IgE-mediated allergy to β-lactams, nonsteroid anti-inflammatory drugs, local anesthetics in 19 patients (16.8%). Previous history of allergy was a risk factor for drug allergy in studied patients (p = 0.001). The most frequent symptoms of allergy were urticaria and erythematous papular rash. Conclusions Drug allergy is a difficult problem in the practice of a doctor and is difficult to diagnose, especially in the pediatric population. It seems that too often isolated symptoms reported during infection or disease are taken as a symptom of drug allergy, and not as a symptom resulting from the course of the disease.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2023, 36, 5; 632-642
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Alergiczne zapalenie pęcherzyków płucnych – kryteria rozpoznania, leczenie, rokowanie i zapobieganie
    Hypersensitivity pneumonitis: Diagnostic criteria, treatment, prognosis and prevention
    Autorzy:
    Jędrych, Małgorzata E.
    Szturmowicz, Monika
    Bestry, Iwona
    Kuś, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/2164310.pdf
    Data publikacji:
    2016-06-30
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    alergiczne zapalenie pęcherzyków płucnych
    diagnostyka
    leczenie
    rokowanie
    tomografia komputerowa płuc o wysokiej rozdzielczości
    BALF
    hypersensitivity pneumonitis
    diagnosis
    treatment
    prognosis
    high resolution chest computed tomography
    Opis:
    Alergiczne zapalenie pęcherzyków płucnych (AZPP) jest chorobą wywoływaną wdychaniem środowiskowych antygenów, najczęściej rozpoznawaną wśród rolników i hodowców ptaków. Rozpoznanie opiera się na stwierdzeniu objawów klinicznych (kaszel i duszność) u osoby narażonej na kontakt z antygenem oraz na wykazaniu w tomografii komputerowej płuc o wysokiej rozdzielczości (TKWR) charakterystycznego obrazu – obustronnych mozaikowatych obszarów zacienień typu matowej szyby z predylekcją do pól środkowych i dolnych, i/lub słabo odgraniczonych guzków środkowej części zrazika, a także cech pułapki powietrznej, lepiej widocznych w fazie wydechowej badania. Taki obraz TKWR najczęściej stwierdzany jest w podostrej postaci AZPP. Pomocne w ustaleniu rozpoznania jest badanie płynu z płukania oskrzelowo-pęcherzykowego (broncho-alveolar lavage fluid – BALF), w którym stwierdza się zwiększenie całkowitej liczby komórek z przewagą limfocytów T (> 50%), szczególnie jeśli towarzyszy mu wzrost liczby neutrofilów (> 3%) i mastocytów (> 1%). Prawidłowy wynik BALF na ogół wyklucza AZPP, chyba że jest to schyłkowe stadium włóknienia. W ustaleniu rozpoznania jest pomocne wykazanie obecności swoistych przeciwciał precypitujących w surowicy chorego. W przypadkach niepewnych rozstrzygający jest wynik badania histopatologicznego materiału z biopsji płuca. Za rozpoznaniem AZPP przemawia obecność małych, słabo uformowanych ziarniniaków, bez cech martwicy, po wykluczeniu innych chorób ziarniniakowych. W leczeniu AZPP najważniejsze jest przerwanie narażenia na antygen. Stosowanie glikokortykosteroidów przynosi szybką poprawę, zwłaszcza w leczeniu ostrych objawów, ale długofalowa skuteczność tych leków jest niepewna. Rokowanie jest na ogół dobre, jeśli zostanie przerwane narażenie na antygen. W niektórych przypadkach dochodzi jednak do postępującego włóknienia płuc, co może prowadzić do ciężkiej niewydolności oddechowej. Med. Pr. 2016;67(4):517–527
    Hypersensitivity pneumonitis (HP) is caused by inhalation of environmental antigens. Farmers and bird keepers are most frequently affected by this desease. The HP diagnosis is based on clinical symptoms (cough, dyspnea) in a person exposed to environmental antigens, and the presence of characteristic changes in high resolution chest computed tomography (HRCT) (bilateral, mosaic, ground glass opacities in the middle and lower lung zones, ill-defined centrilobular nodules and the sign of air-trapping on expiration). This type of HRCT pattern is most frequently found in the patients with subacute HP. Bronchioloalveolar lavage fluid (BALF) examination is helpful in establishing the HP diagnosis, when the increased total number of cells, with the predominance of T lymphocytes (> 50%), and the increased number of neutrophils (> 3%) and mastocytes (> 1%) are found. The presence of specific serum precipitins increases the likelihood of HP. In case of atypical clinical presentation, lung biopsy is recommended. The diagnostic criterion of HP is the presence of ill-defined non-necrotising granulomas, after excluding other granulomatous lung diseases. The prevention and treatment of HP is based on the elimination of the antigen from the environment. Corticosteroids may contribute to the improvement in the acute and sub-acute form of the disease but their long term effectiveness is uncertain. The prognosis of HP patients is generally perceived as good, especially in those patients in whom antigen avoidance is possible. Nevertheless, in some patients progressive pulmonary fibrosis and development of severe respiratory insufficiency is observed. Med Pr 2016;67(4):517–527
    Źródło:
    Medycyna Pracy; 2016, 67, 4; 517-527
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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