- Tytuł:
- An association between cumulative exposure to light at night and the prevalence of hyperuricemia in steel workers
- Autorzy:
-
Li, Xiaoming
Xu, Xianghui
Song, Yang
Cui, Shiyue
Xue, Chao
Wang, Lihua
Wu, Jianhui
Yuan, Juxiang - Powiązania:
- https://bibliotekanauki.pl/articles/2085783.pdf
- Data publikacji:
- 2021-06-28
- Wydawca:
- Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
- Tematy:
-
uric acid
circadian rhythms
hyperuricemia
steel workers
light at night
restricted cubic spline - Opis:
- ObjectivesExposure to light at night (LAN) can disturb circadian endocrine and metabolic rhythms. Hyperuricemia (HUA) is an early-onset metabolic disorder. However, it is still not clear whether LAN exposure increases the prevalence of HUA.Material and MethodsThe authors used crosssectional data on the Beijing-Tianjin-Hebei occupational populations cohort from March–July 2017. A total of 7664 steel workers were finally selected to investigate the relationship between LAN exposure and the prevalence of HUA among steel workers. The authors collected demographic and socio-economic data, as well as information on lifestyle factors, anthropometric measures, and laboratory tests. The restricted cubic spline method was used to analyze the dose-response relationship between cumulative LAN exposure and the prevalence of HUA. Logistic regression analyses were used to fit the relationship between them.ResultsThe average age of the participants was 43.5±8.6 years; 7051 (91.7%) of them were males, 2749 (35.9%) reported to suffer from HUA, and 1241 (16.2%) were not exposed to LAN. There was a significant non-linear dose-response relationship between them. After adjustment for the confounding factors, including demographic data, lifestyle factors, etc., the lower LAN exposure was significantly associated with HUA (0–1931.7 days, OR = 1.180, and the 95% CI: 1.000–1.394; 1931.7–4343 days, OR = 1.215, 95% CI: 1.035–1.426).ConclusionsThis study revealed that a certain amount of exposure to LAN is independently related to the prevalence of HUA in steel workers in China.
- Źródło:
-
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 3; 385-401
1232-1087
1896-494X - Pojawia się w:
- International Journal of Occupational Medicine and Environmental Health
- Dostawca treści:
- Biblioteka Nauki