Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "breath condensate" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Exhaled breath malondialdehyde, spirometric results and dust exposure assessment in ceramics production workers
Autorzy:
Sakhvidi, Mohammad J.
Biabani Ardekani, Javad
Firoozichahak, Ali
Zavarreza, Javad
Hajaghazade, Mohammad
Mostaghaci, Mehrdad
Mehrparvar, Amirhooshang
Barkhordari, Abolfazl
Powiązania:
https://bibliotekanauki.pl/articles/2177001.pdf
Data publikacji:
2015-02-24
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
Oxidative stress
occupational exposures
spirometry
breath condensate
malondialdehyde
Opis:
Introduction The study aimed at measuring exhaled breath malondialdehyde (EBC-MDA) in workers exposed to dust containing silica and at its comparison with the non-exposed control group. Material and methods The cross sectional, case-control study (N = 50) was performed in a tile and ceramics production factory in Yazd, Iran. EBC-MDA was quantified in exhaled breath of the participants by a lab made breath sampler. Exposure intensity was measured according to the NIOSH 0600 method in selected homogeneous exposure groups. Additionally, spirometry test was conducted to investigate a correlation between EBC-MDA and spirometric findings in the exposed workers. Results There was no difference in the observed exposure intensities of silica containing dust in different units. However, “coating preparation” was the unit with the highest concentration of dust. Although, the level of EBC-MDA in the cases was slightly higher than in the controls, the difference was not statistically significant (U = 252, p = 0.464). A significant and positive correlation was found between dust exposure intensity in working units and the measured EBC-MDA of workers (r = 0.467, N = 25, p = 0.027). There were also no statistically significant differences among job categories in the exposed group for the values of FEV1% (F(3, 44) = 0.656, p = 0.584), FVC% (F(3, 44) = 1.417, p = 0.172), and FEV1/FVC% (F(3, 44) = 1.929, p = 0.139). Conclusions The results showed a significant correlation between respirable dust exposure intensity and the level of EBC-MDA of the exposed subjects. However, our results did not show a significant correlation between lung function decreases and EBC-MDA.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 1; 81-89
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Occupational asthma follow-up — Which markers are elevated in exhaled breath condensate and plasma?
Autorzy:
Pelclová, Daniela
Fenclová, Zdenka
Vlčková, Štěpánka
Klusáčková, Pavlína
Lebedová, Jindřiška
Syslová, Kamila
Běláček, Jaromír
Kuzma, Marek
Navrátil, Tomáš
Zakharov, Sergey
Kačer, Petr
Powiązania:
https://bibliotekanauki.pl/articles/2178829.pdf
Data publikacji:
2014-05-17
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational asthma
exhaled breath condensate
eosinophilic cationic protein
8-isoprostane
leukotrienes
methacholine
Opis:
Objectives: To search for optimal markers in the exhaled breath condensate (EBC), plasma and urine that would reflect the activity/ severity of occupational asthma (OA) after the withdrawal from the exposure to the allergen. Material and Methods: Markers of oxidative stress: 8-iso-prostaglandin $ \text{F}_\text{2α}$ (8-isoprostane, 8-ISO), malondialdehyde (MDA), 4-hydroxy-trans-2-nonenale (HNE), cysteinyl leukotrienes (LT) and LTB₄ were determined using liquid chromatography and mass spectrometry in 43 subjects with immunological OA (49.3±11.8 years), removed from the exposure to the sensitizing agent 10.5±6.5 years ago; and in 20 healthy subjects (49.0±14.9 years). EBC was harvested both before and after the methacholine challenge test. In parallel, identical markers were collected in plasma and urine. The results were analyzed together with forced expiratory volume in one second (FEV1), blood eosinophils, immunoglobulin E (IgE) and eosinophilic cationic protein (ECP) and statistically evaluated (Spearman rank correlation $r_S$, two- or one-sample t tests and alternatively Kruskal Wallis or pair Wilcoxon tests). Results: Several parameters of lung functions were lower in the patients (FEV₁% predicted, MEF25% and MEF50%, Rtot%, p < 0.001). Shorter time interval since the removal from the allergen exposure correlated with higher ECP ($r_S$ = 0.375) and lower FEV1%, MEF25% and MEF50% after methacholine challenge ($r_S$ = -0.404, -0.425 and -0.532, respectively). In the patients, IgE (p < 0.001) and ECP (p = 0.009) was increased compared to controls. In EBC, 8-ISO and cysteinyl LTs were elevated in the asthmatics initially and after the challenge. Initial 8-ISO in plasma correlated negatively with FEV₁ ($r_S$ = -0.409) and with methacholine PD₂₀ ($r_S$ = -0.474). 8-ISO in plasma after the challenge correlated with IgE ($r_S$ = 0.396). Conclusions: The improvement in OA is very slow and objective impairments persist years after removal from the exposure. Cysteinyl LTs and 8-ISO in EBC and 8-ISO in plasma might enrich the spectrum of useful objective tests for the follow-up of OA.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2014, 27, 2; 206-215
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies