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Wyświetlanie 1-6 z 6
Tytuł:
β-syntaza cystationiny (CBS), γ-liaza cystationiny (CSE) i oksydaza cytochromu c (COX) w surowicy górników kopalni miedzi potencjalnie narażonych na emisje siarkowodoru
Serum cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE ) and cytochrome c oxidase (COX) in copper mine miners potentially expose d to hydrogen sulfide
Autorzy:
Skoczyńska, Anna
Gruszczyński, Leszek
Turczyn, Barbara
Ścieszka, Marek
Wojakowska, Anna
Pawłowski, Tomasz
Schmidt, Edward
Powiązania:
https://bibliotekanauki.pl/articles/2164440.pdf
Data publikacji:
2015-09-28
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
górnicy
siarkowodór
oksydaza cytochromu c
β-syntaza cystationiny
γ-liaza cystationiny
kopalnia miedzi
miners
hydrogen sulfide
Cytochrome C oxidase
cystathionine β-synthase
cystathionine γ-lyase
copper mine
Opis:
Wstęp Celem badań była ocena stężenia mitochondrialnego enzymu docelowego dla toksycznego działania siarkowodoru, tj. oksydazy cytochromu c (COX) oraz enzymów uczestniczących w syntezie endogennego H₂S (siarkowodoru) – syntazy β-cystationiny (CBS) i γ-liazy cystationiny (CSE) w surowicy górników kopalni miedzi. Materiał i metody Badanie wstępne przeprowadzono u 237 górników, a zasadnicze u 88 górników zatrudnionych w 2 szybach: I – bez zarejestrowanych emisji H₂S w ciągu ostatnich 10 lat (grupa badana A); II – w którym występowały emisje H₂S (grupa badana B). U górników przeprowadzono badania lekarskie i bezpośrednio po wyjeździe z kopalni na powierzchnię pobrano od nich po 10 ml krwi żylnej. Wyniki Nie stwierdzono żadnych zmian klinicznych ani biochemicznych, typowych dla toksycznego działania siarkowodoru. Stężenie sulfhemoglobiny było nieoznaczalne, nie stwierdzono zmian w układzie oksydo-redukcyjnym. W grupie B wykazano natomiast zmiany regulacyjne, które mogą być wynikiem powtarzanych ekspozycji na H₂S. Do tych zmian należy wyższe stężenie CBS i CSE w surowicy, wzrost aktywności enzymu konwertującego angiotensynę (ACE) w porównaniu z grupą A oraz liniowa zależność między ACE a CSE (r = 0,6927; p < 0,001). Wykazano, że palenie papierosów obniża stężenie COX (p < 0,05), jednak u górników zatrudnionych w szybie II obniżenie stężenia COX może wynikać, poza paleniem, także z obecności siarkowodoru w gazach kopalnianych. Wnioski Stężenie COX może być czułym wskaźnikiem ekspozycji na siarkowodór. Pomiary stężenia siarkowodoru we krwi przeprowadzane na stanowiskach pracy powinny wyjaśnić przyczynę zmian w aktywności COX, CBS i CSE. Med. Pr. 2015;66(4):539–548
Background The aim of the study was to evaluate serum levels of the target enzyme for H2S toxicity – cytochrome c oxidase (COX) and enzymes involved in the synthesis of H₂S – cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) in copper mine miners. Material and Methods The initial and basic study was conducted respectively in 237 and 88 miners, working in 2 mining shafts: I – no H₂S emissions recorded in the last 10 years (study group A) and II – H₂S emissions occurred (study group B). A medical examination was performed and 10 ml of blood was collected from miners immediately after exiting the mine. Results There were no clinical or biochemical changes typical for H₂S toxicity. Sulfhemoglobine was undetectable and there were no changes in the red-ox system. However, in group B, regulatory changes were found; a tendency to higher concentration of CBS and CSE, a higher activity of angiotensin converting enzyme (ACE) compared to group A (p < 0.05) and a linear relationship between ACE and CSE (r = 0.6927; p < 0.001). It has been shown that cigarette smoking decreases COX (p < 0.05), however, in miners working in shaft II, the decreased level of COX may result also from the presence of H₂S in the gaseous emissions. Conclusions COX concentration can be a sensitive indicator of exposure to H₂S. The measurements of blood H₂S concentrations carried out in workplaces should explain the cause of the changes observed in the COX, CBS and CSE activity. Med Pr 2015;66(4):539–548
Źródło:
Medycyna Pracy; 2015, 66, 4; 539-548
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Employment after lung transplantation in Poland – a single center study
Autorzy:
Ochman, Marek
Latos, Magdalena
Orzeł, Gabriela
Pałka, Paulina
Urlik, Maciej
Nęcki, Mirosław
Stącel, Tomasz
Zembala, Marian
Powiązania:
https://bibliotekanauki.pl/articles/2161970.pdf
Data publikacji:
2019-06-14
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational medicine
cystic fibrosis
lung transplantation
solid organ transplantation
employment in Poland
employment after transplantation
Opis:
Objectives Lung transplantation not only saves a patient’s life but also creates the opportunity for becoming more self-reliant and getting back to work. The aim of this single center study was to assess the prospects of employment, as well as its influence on the quality of life and physical activity, of the lung transplant recipients of the Silesian Center for Heart Diseases in Zabrze, Poland. Material and Methods A retrospective study covered 67 lung transplant recipients of the Silesian Center of Heart Diseases. Only patients with ≥ 6-month follow-up were included. All of the patients gave their written consent to be included in the study before filling out the questionnaire containing questions about employment, income, education and how work affected their quality of life before and after lung transplantation. A physical capability assessment was performed by climbing flights of stairs and by means of a 6-min walk test, and spirometry parameters were also measured. Results Twenty of the patients included in the study (31.7%) were employed after lung transplantation, 63.2% of whom worked full-time. Profession was changed by 2 patients (14.3%). The patients diagnosed with cystic fibrosis were found to have the highest chance of finding employment after lung transplantation. The statistical analysis revealed that the employed patients were able to cover longer distances during the 6-min walk test (556 m, on average) than the unemployed ones (494 m, on average). Conclusions One in 3 patients finds employment after lung transplantation. Work improves the quality of life of the majority of lung transplant recipients. The patients who are employed are also in a better physical condition, and they are more self-reliant in comparison to those who remain unemployed. Lung transplant recipients with cystic fibrosis are most likely to find employment, and so are patients with higher education. Int J Occup Med Environ Health. 2019;32(3):379–86
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2019, 32, 3; 379-386
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Predictors of stress among emergency medical personnel during the COVID-19 pandemic
Autorzy:
Ilczak, Tomasz
Rak, Małgorzata
Ćwiertnia, Michał
Mikulska, Monika
Waksmańska, Wioletta
Krakowiak, Anna
Bobiński, Rafał
Kawecki, Marek
Powiązania:
https://bibliotekanauki.pl/articles/2086071.pdf
Data publikacji:
2021-05-27
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational stress
emergency medical services
COVID-19 pandemic
predictors of stress
medical professionals
emergency procedures
Opis:
ObjectivesThe COVID-19 pandemic has forced emergency services to implement new standards of practice around the world. The dynamic and unpredictable nature of many clinical situations has placed emergency service personnel in direct danger of contracting the disease. This work uses a validated survey developed for the study to assess the predictors of stress that paramedics, nurses and doctors experience in the face of the COVID-19 pandemic.Material and MethodsThe study group included 955 medical staff, and the level of significance adopted for statistical analysis was p = 0.05. Non-parametric Mann-Whitney and Kruskal-Wallis tests were used to analyze the qualitative variables divided into groups. The selection of tests was carried out based on the distribution of variables, verified using the Shapiro-Wilk test. In order to determine the predictors that caused the feelings of stress, it was necessary to use the linear regression model.ResultsDuring the COVID-19 pandemic, stress among emergency medical personnel has increased considerably due to new factors that did not previously exist. The predictors of stress in the professional environment include the fear of contracting COVID-19, a decrease in the level of safety while conducting emergency medical procedures, and the marginalization of treatment for patients not suffering from COVID-19. Additional socio-demographic factors that increase stress among emergency medical personnel are being female and working in the nursing profession. Appropriate training, the supply of personal protective equipment and opinions on the preparedness of the system to deal with the outbreak of the pandemic did not affect the level of stress among health service personnel.ConclusionsThe factors that can be considered to act as predictors of occupational stress include the fear of contracting COVID-19, a decrease in the level of safety and security while conducting emergency medical procedures, and the marginalization of patients not suffering from COVID-19.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 2; 139-149
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zmiany wybranych wskaźników fizjologicznych oraz ocena stresu cieplnego pod wpływem kąpieli w saunie suchej i mokrej u młodych zdrowych kobiet
Changes in selected physiological indicators and thermal stress assessment under the influence of baths in a dry and wet sauna in young healthy women
Autorzy:
Pilch, Wanda
Piotrowska, Anna
Czerwińska-Ledwig, Olga
Zuziak, Roxana
Maciejczyk, Marcin
Tota, Łukasz
Bawelski, Marek
Pałka, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/2162643.pdf
Data publikacji:
2019-12-03
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
temperatura ciała
sauna sucha
sauna mokra
stres cieplny
odczuwanie temperatury
obciążenie fizjologiczne
body temperature
dry sauna
wet sauna
heat stress
temperature sense
physiological strain
Opis:
Wstęp Kąpiele w saunie suchej i w łaźni parowej ze względu na różny stopień obciążenia cieplnego wywołują też różne reakcje organizmu. Duża wilgotność powietrza w saunie mokrej utrudnia parowanie potu ze skóry. Ponadto dynamika pocenia się jest różna u kobiet i mężczyzn. Celem pracy była analiza zmian wskaźników fizjologicznych oraz porównanie wpływu sauny suchej i mokrej na odczucie komfortu cieplnego ocenianego w skali termicznej Bedforda, a także zbadanie wielkości obciążenia fizjologicznego (physiological strain index – PSI) i skumulowanego wskaźnika obciążeń cieplnych (cumulative heat stress index − CHSI) u młodych zdrowych kobiet. Materiał i metody W badaniach wzięło udział 10 kobiet w wieku 22−24 lat. Pomiary w obu typach sauny prowadzono w fazie folikularnej cyklu miesięcznego. Każda sesja trwała 60 min i składała się z trzech 15-minutowych ekspozycji cieplnych z 5-minutowymi przerwami na odpoczynek i schłodzenie wodą. Temperatura w saunie suchej wynosiła 91±1,2°C, w mokrej – 59±1,3°C; wilgotność powietrza, odpowiednio: 18±0,7% i 60,5±0,8%. Dokonano pomiarów masy ciała, ciśnienia skurczowego (systolic blood pressure − SBP) i rozkurczowego (diastolic blood pressure − DBP), częstości skurczów serca (heart rate − HR), temperatury rektalnej ($ \text{T}_\text{re} $) i odczuć termicznych według skali Bedforda. Wyliczono współczynniki obciążenia fizjologicznego: PSI oraz CHSI. Wyniki Po saunie suchej średnie ubytki masy ciała badanych kobiet były istotnie wyższe niż po kąpieli w saunie mokrej. Po zabiegu w saunie mokrej zaobserwowano istotnie większe przyrosty $ \text{T}_\text{re} $ oraz HR. Oba zabiegi powodowały wzrost SBP. Podczas obu kąpieli ciśnienie rozkurczowe ulegało obniżeniu. Subiektywne odczucie uciążliwości zabiegu oraz PSI i CHSI było większe podczas kąpieli w saunie mokrej. Wnioski Ekspozycja cieplna w saunie mokrej stanowi większe obciążenie dla organizmu młodych kobiet niż taki sam zabieg w saunie suchej, a zmiany badanych cech są większe od tych, które zaobserwowano u mężczyzn poddanych podobnym obciążeniom termicznym. Med. Pr. 2019;70(6):701–710
Background There are differences between dry and wet sauna baths because of the heat load and human body’s reactions. High humidity in a wet sauna makes evaporation of sweat from the skin surface more difficult. In addition, the dynamics of sweating is different in men and women. The aim of the study was to assess changes in physiological indicators and to compare the impact of dry and wet saunas on the thermal comfort feeling, which was assessed using the Bedford thermal scale, and the physiological strain index (PSI) and the cumulative heat stress index (CHSI) in young healthy women. Material and Methods Ten women aged 22−24 years took part in the study. A session in each sauna lasted 60 min and consisted of 3 thermal 15-min exposures, in 5-min intervals for rest and cooling with water. The temperature in the dry sauna was 91±1.2°C and in the wet sauna 59±1.3°C, while the humidity was 18±0.7% and 60.5±0.8%, respectively. Body weight, systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), rectal temperature ($ \text{T}_\text{re} $) and the thermal sensation (Bedford scale) were also measured. The PSI and CHSI values were both calculated. Results The average weight loss after a dry sauna bath was significantly higher than after a wet sauna bath. Significantly higher increases in $ \text{T}_\text{re} $, as well as in HR were observed after treatment in the wet sauna, compared to the dry sauna. Both treatments resulted in an increase in SBP and a decrease in DBP. The arduousness of thermal discomfort and the levels of PSI and CHSI were skurgreater in the wet sauna bathing than in the dry sauna. Conclusions Heat exposure in the wet sauna creates a greater burden for young women’s bodies than the same dry sauna treatment, and the changes observed in the examined traits were higher than in men subjected to similar thermal loads. Med Pr. 2019;70(6):701–10
Źródło:
Medycyna Pracy; 2019, 70, 6; 701-710
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A subjective sense of the quality of life in adolescents from the Świętokrzyskie Voivodship
Autorzy:
Jasińska, Małgorzata
Sikorski, Marek
Wójcik, Tomasz
Chmielewski, Jarosław
Florek-Łuszczki, Magdalena
Sierpiński, Radosław
Szpringer, Monika
Nowak-Starz, Grażyna
Powiązania:
https://bibliotekanauki.pl/articles/2085763.pdf
Data publikacji:
2021-06-28
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
self-assessment
adolescents
quality of live
KIDSCREEN-52 questionnaire
Świętokrzyskie Voivodship
diagnostic survey
Opis:
ObjectivesThe measurement of the health-related quality of life (HRQOL) is one of the most important methods for self-assessment of health, which makes it possible to identify irregularities in the physical, mental and social functioning. The aim of the research was to determine HRQOL using the Health Related Quality of Life Questionnaire for Children and Young People (the KIDSCREEN-52 questionnaire) – the instrument recommended by the World Health Organization – which makes it possible to distinguish groups of adolescents with a diversified subjective sense of the quality of life.Material and MethodsThe study involved a group of 871 adolescents, 411 boys and 460 girls, aged 13–16 years, residing in the Świętokrzyskie Voivodship. The method of a diagnostic survey was used in the research. The KIDSCREEN-52 questionnaire, which is an instrument for examining the HRQOL of adolescents, was employed in the study. The k-means clustering method was applied, which made it possible to establish 3 groups of adolescents with a different subjective sense of the quality of life.ResultsThree groups of adolescents with a diversified subjective sense of the quality of life (high, average, low) were identified using the KIDSCREEN-52 questionnaire. The subjective quality of life in the majority of the respondents was high, in particular in those living in rural areas. The surveyed boys with a high subjective quality of life showed a significantly higher self-esteem, acceptance and peer support than the surveyed girls.ConclusionsThe KIDSCREEN-52 questionnaire is an accurate and sensitive tool for assessing HRQOL. It allows identifying 3 groups of adolescents with a diversified subjective sense of the quality of life. It can form the basis for further diagnosis of the bio-psycho-social functioning of adolescents.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 3; 415-425
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the impact of atmospheric pressure in different seasons on blood pressure in patients with arterial hypertension
Autorzy:
Kamiński, Marek
Cieślik-Guerra, Urszula I.
Kotas, Rafał
Mazur, Piotr
Marańda, Witold
Piotrowicz, Maciej
Sakowicz, Bartosz
Napieralski, Andrzej
Trzos, Ewa
Uznańska-Loch, Barbara
Rechciński, Tomasz
Kurpesa, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/2168335.pdf
Data publikacji:
2016-07-22
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
arterial hypertension
atmospheric pressure
Ambulatory blood pressure monitoring
ABPM
impact of weather on health
weather
Opis:
Objectives Atmospheric pressure is the most objective weather factor because regardless of if outdoors or indoors it affects all objects in the same way. The majority of previous studies have used the average daily values of atmospheric pressure in a bioclimatic analysis and have found no correlation with blood pressure changes. The main objective of our research was to assess the relationship between atmospheric pressure recorded with a frequency of 1 measurement per minute and the results of 24-h blood pressure monitoring in patients with treated hypertension in different seasons in the moderate climate of the City of Łódź (Poland). Material and Methods The study group consisted of 1662 patients, divided into 2 equal groups (due to a lower and higher average value of atmospheric pressure). Comparisons between blood pressure values in the 2 groups were performed using the Mann-Whitney U test. Results We observed a significant difference in blood pressure recorded during the lower and higher range of atmospheric pressure: on the days of the spring months systolic (p = 0.043) and diastolic (p = 0.005) blood pressure, and at nights of the winter months systolic blood pressure (p = 0.013). Conclusions A significant inverse relationship between atmospheric pressure and blood pressure during the spring days and, only for systolic blood pressure, during winter nights was observed. Int J Occup Med Environ Health 2016;29(5):783–792
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2016, 29, 5; 783-792
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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