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    Wyświetlanie 1-3 z 3
    Tytuł:
    Enriched water-H2 18 O purification to be used in routine 18FDG production
    Autorzy:
    Al Rayyes, A. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/148761.pdf
    Data publikacji:
    2010
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    H2 18 O
    radiopharmaceuticals
    purification
    18FDG
    Opis:
    18O-water obtained from an 2-deoxy-2-[18F]-fluoro-D-glucose (18FDG, Synthera) synthesis unit is used for purification. The purification process consists of ultraviolet (UV) irradiation followed by a distillation in a preevacuated system. After purification, the loss of enriched water was about only 5 per cent. Organic compounds, radioisotopes, trace metals and gases are eliminated efficiently. Results show that there is no significant difference in the production yield of 2-deoxy-2-[18F]-fluoro-D-glucose ([18F]FDG) whether using purified enriched water by the proposed method of purification or using the new enriched water. This method offers the necessary precaution from contamination by tritium during the purification process. The obtained 18FDG or Na-18F using the purified 18O-water is of tritium free.
    Źródło:
    Nukleonika; 2010, 55, 3; 401-405
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Radiation doses to technologists working with 18F-FDG in a PET center with high patient capacity
    Autorzy:
    Demir, M.
    Demir, B.
    Yaşar, D.
    Sayman, H. B.
    Halac, M.
    Ahmed, A. S.
    Özcan, K.
    Uslu, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/148501.pdf
    Data publikacji:
    2010
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    whole-body dose
    finger doses
    personnel dosimetry
    18F-FDG
    PET-CT
    Opis:
    The increasing numbers of PET studies for routine diagnosis creates a real hazard to radiation workers. The aim of this study is to estimate the annual whole-body and finger radiation dose to technologists working with 18F-FDG in a PET center with high patient potential. In our PET center, the number of PET imaging has increased almost to 5000 studies per year. Our standard dose for tumor imaging is 518 MBq of 18F-FDG. Five technologists performing all steps of 18F-FDG imaging (5 patients per technologist in a day) were officially involved round the week for handling and injecting 18F-FDG to patients. Whole-body and finger dose measurements with TLDs were performed for two different time periods: i) before shielding precautions during the first 6 months (without a shielding for sterile syringe and without a lead container for shielded syringe) and ii) after shielding precautions during the next 6 months (with a shielding for sterile syringe and with a lead container for shielded syringe). The average annual whole-body radiation dose for one technologist before shielding precautions was 7.82 mSv and after shielding precautions was 5.76 mSv. On the other hand, while the average annual finger radiation doses for one technologist before shielding precautions were 210.36 and 293.72 mSv for the left and right hand, after shielding precautions were they 158.16 and 217.58 mSv for the left and right hand, respectively. According to our results, if one technologist performs the whole-body PET imaging of 5 patients per day, the annual radiation dose to this technologist will not exceed the recommended limits by ICRP.
    Źródło:
    Nukleonika; 2010, 55, 1; 107-112
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Production of [18F] fluoride with a high-current two layer spherical gold target
    Autorzy:
    Mirzaii, M.
    Afarideh, H.
    Hadji-Saeid, S.
    Aslani, G.
    Ensaf, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/147973.pdf
    Data publikacji:
    2004
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    water target
    [18F] fluorine
    FDG
    PET
    high current
    Opis:
    A new automated target for high yield production of aqueous [18F] fluoride at high beam currents has been constructed for a cyclotron at NRCAM in Karaj (Cyclone 30). It consists of one small golden sphere inside another target chamber, mounted into a special holder, which provides rapid cooling by water flow around and inside the sphere. The target is irradiated with 28 MeV protons. The incident energy on the target chamber is 18 MeV. This target is operated without external overpressure and has been tested for beam currents up to 60 ěA. The measured target yield is 80% of the theoretically calculated yield of 18F, which is used for the synthesis of [18F] 2-fluoro-2-deoxy-D-glucose.
    Źródło:
    Nukleonika; 2004, 49, 1; 23-27
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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