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Wyszukujesz frazę "Rydygier, M." wg kryterium: Autor


Wyświetlanie 1-3 z 3
Tytuł:
Studies of scintillator response to 60 MeV protons in a proton beam imaging system
Autorzy:
Rydygier, M.
Mierzwińska, G.
Czaderna, A.
Swakoń, J.
Waligórski, M. P. R.
Powiązania:
https://bibliotekanauki.pl/articles/146249.pdf
Data publikacji:
2015
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
beam imaging
CCD camera
scintillation detector
Opis:
A Proton Beam Imaging System (ProBImS) is under development at the Institute of Nuclear Physics, Polish Academy of Sciences (IFJ PAN). The ProBImS will be used to optimize beam delivery at IFJ PAN proton therapy facilities, delivering two-dimensional distributions of beam profiles. The system consists of a scintillator, optical tract and a sensitive CCD camera which digitally records the light emitted from the proton-irradiated scintillator. The optical system, imaging data transfer and control software have already been developed. Here, we report preliminary results of an evaluation of the DuPont Hi-speed thick back screen EJ 000128 scintillator to determine its applicability in our imaging system. In order to optimize the light conversion with respect to the dose locally deposited by the proton beam in the scintillation detector, we have studied the response of the DuPont scintillator in terms of linearity of dose response, uniformity of light emission and decay rate of background light after deposition of a high dose in the scintillator. We found a linear dependence of scintillator light output vs. beam intensity by showing the intensity of the recorded images to be proportional to the dose deposited in the scintillator volume.
Źródło:
Nukleonika; 2015, 60, No. 3, part 2; 683-687
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of the micronucleus assay performed by different scorers in case of large-scale radiation accidents
Autorzy:
Rawojć, K.
Tarnawska, D. M.
Miszczyk, J. U.
Swakoń, J.
Stolarczyk, L.
Rydygier, M.
Powiązania:
https://bibliotekanauki.pl/articles/146534.pdf
Data publikacji:
2015
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
biological dosimetry
cytokinesis-blocked micronucleus assay
frequency of micronuclei
Opis:
Mass casualty scenarios of radiation exposure require high throughput biological dosimetry techniques for population triage, in order to rapidly identify individuals, who require clinical treatment. Accurate dose estimates can be made by biological dosimetry, to predict the acute radiation syndrome (ARS) within days after a radiation accident or a malicious act involving radiation. Timely information on dose is important for the medical management of acutely irradiated persons [1]. The aim of the study was to evaluate the usefulness of the micronuclei (MNi) scoring procedure in an experimental mode, where 500 binucleated cells were analyzed in different exposure dose ranges. Whole-body exposure was simulated in an in vitro experiment by irradiating whole blood collected from one healthy donor with 60 MeV protons and 250 keV X-rays, in the dose range of 0.3–4.0 Gy. For achieving meaningful results, sample scoring was performed by three independent persons, who followed guidelines described in detail by Fenech et al. [2, 3]. Compared results revealed no signifi cant differences between scorers, which has important meaning in reducing the analysis time. Moreover, presented data based on 500 cells distribution, show that there are significant differences between MNi yields after 1.0 Gy exposure of blood for both protons and X-rays, implicating this experimental mode as appropriate for the distinction between high and low dose-exposed individuals, which allows early classification of exposed victims into clinically relevant subgroups.
Źródło:
Nukleonika; 2015, 60, No. 3, part 2; 643-649
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of alanine dosimetry in dose assessment for ocular melanoma patients undergoing proton radiotherapy : preliminary results
Autorzy:
Mierzwińska, G.
Kłodowska, M.
Michalec, B.
Pędracka, A.
Rydygier, M.
Swakoń, J.
Waligórski, M. P. R.
Powiązania:
https://bibliotekanauki.pl/articles/146382.pdf
Data publikacji:
2015
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
alanine
EPR dosimetry
proton beam
proton radiotherapy
Quality Assurance (QA)
Opis:
Basing on alanine solid state/electron paramagnetic resonance (EPR) dosimetry, a supplementary method of cumulatively recording the therapeutic dose received by ocular cancer patients undergoing fractionated proton radiotherapy is proposed. By applying alanine dosimetry during the delivery of consecutive fractions, the dose received within each fraction can be read out by EPR spectrometry and a fi nal permanent cumulative record of the total dose delivered obtained. The dose response of the alanine detector was found to be practically independent on its position within the extended proton Bragg peak region. Dose measurements based on entrance dose recorded in proton beams individually formed for each patient are presented. The described method will be applied as a complementary Quality Assurance procedure for patients undergoing proton radiotherapy at the Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland (IFJ PAN).
Źródło:
Nukleonika; 2015, 60, No. 3, part 2; 609-613
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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