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Wyszukujesz frazę "dysfunction," wg kryterium: Temat


Wyświetlanie 1-4 z 4
Tytuł:
Combination therapy of tadalafil and pentoxifylline in severe erectile dysfunction; a prospective randomized trial
Autorzy:
Kumar, Santosh
Roat, Rajesh
Agrawal, Swat
Jayant, Kumar
Mavuduru, Ravimohan
Kumar, Shrawan
Powiązania:
https://bibliotekanauki.pl/articles/1394362.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
erectile dysfunction
PDE5 inhibitors
Tadalafil
Pentoxyfilline
Opis:
The aim of the study was to assess efficacy of Tadalafil alone versus Tadalafil plus Pentoxifylline in the treatment of erectile dysfunction by using self administered IIEF-5 questionnaire. Material and methods. Two hundred and thirty seven patients presenting with ED at andrology OPD were evaluated for ED by a self administered IIEF (International Index of Erectile Function) questionnaire. Patients were systematically randomized by computer generated random table into two groups groups namely, group A: Tadalafil only group, group B: combination of Tadalafil + Pentoxifylline. All the patients were re-assessed by IIEF-5 questionnaire after 8 weeks of medical therapy. Statistical analysis was performed using student’s unpaired t-test, paired t-test, chi square test. pvalue < 0.05 was considered statistically significant. Results. Two hundred and thirty seven patients were included in the present study, in group A: 92 patients (78.6%) showed improvement in their IIEF score after 8 weeks of tadalafil treatment. While in group B, overall 104 patients(86.6%) showed improvement after combination of Tadalafil and Pentoxifylline. There was a statistically significant difference of percentage change in IIEF score was seen in group B (group A 90.7±15.2%, group B 95.6±13.4%; p value – 0.014). We found this difference even more statistically significant in patients with severe ED (group A 72.7±47.2%, group B 132.3±54.3%; p value – 0.000). There was no significant difference in between the two groups with regards to occurrence of side effects. Conclusions. Both tadalafil and combination of Tadalafil + Pentoxifylline improve erectile function in patients of ED. Patients with severe ED showed much significant improvement in erectile function with combination therapy.
Źródło:
Polish Journal of Surgery; 2015, 87, 8; 377-383
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Transjugular Intrahepatic Portosystemic Shunt in patients after orthotopic liver transplantation (OLTx) due to life threatening gastrointestinal hemorrhage. A single-center experience based on three cases and literature review
Autorzy:
Januszewicz, Magdalena
Włodarczyk-Pruszyńska, Inga
Milczarek, Krzysztof
Rowińska-Berman, Katarzyna
Zieniewicz, Krzysztof
Wróblewski, Tadeusz
Rowiński, Olgierd
Powiązania:
https://bibliotekanauki.pl/articles/1392272.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
Transjugular Portasystemic Shunt
variceal bleeding
OLTx
graft dysfunction
Opis:
Background: Transjugular intrahepatic portosystemic shunt system (TIPS) is a well-recognized method of treatment of symptomatic portal hypertension in patients awaiting liver transplantation. The effectiveness of TIPS treatment in patients after liver transplantation is still not fully established. Indications for both groups of patients, with and without liver graft, are similar and include bleeding from gastrointestinal varices, ascites, pleural effusion, and Budd-Chiari syndrome. Feasibility of TIPS in emergency treatment in patients after OLTx due to life-threatening hemorrhage is not well described. Materials and methods: Patients, after OLTx performed using classical, non-piggyback technique had severe hemorrhages from gastrointestinal varices due to lost graft function. Patients were in an unstable condition, required blood transfusions on admittance and monitoring in Intensive Care Unit. TIPS were implanted urgently, after unsuccessful endoscopic treatment, as a life-saving procedure. Results: In all cases, the procedure was successfully completed. The bleeding did not reoccur during the postoperative course. Conclusion: TIPS procedure appears to be justified as a bridge to a planned retransplantation, or as a treatment of choice in patients disqualified from retransplantation. Emergency performance of the TIPS procedure as a treatment for acute variceal bleeding should still be considered individually for each patient and only as a procedure leading to further treatment.
Źródło:
Polish Journal of Surgery; 2019, 91, 2; 38-44
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sexual dysfunctions following low anterior resection of the rectum in rectal cancer patients
Autorzy:
Włodarczyk, Marcin
Sobolewska, Justyna
Nowak, Artur
Szewczyk, Martyna
Kluska, Piotr
Dzika, Katarzyna
Darnikowska, Justyna
Mik-Wojtczak, Joanna
Włodarczyk, Jakub
Sobolewska-Włodarczyk, Aleksandra
Trzciński, Radzisław
Dziki, Łukasz
Powiązania:
https://bibliotekanauki.pl/articles/1391931.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
sexual dysfunction
rectal cancer
low anterior resection
surgical treatment outcomes
Opis:
Introduction. Low anterior resection of the rectum (LAR) is a treatment of choice in patients with diagnosed low rectal cancer. Rectal cancer surgery has a close relationship with the urinary-sexual organs and also with related nerves and nerve plexus. Thus, the sympathetic and parasympathetic nerves of the pelvic area may be damaged. As a result of this, the important point is the sexual function loss following rectal surgeries. The aim of the study was to investigate the sexual disorders in patients with rectal cancer who underwent LAR. Materials and methods. In this retrospective study the sexual activity, comfort of the experience, quality of sexual life (QoSL) during 3 periods were analyzed: before surgery, a month after and half a year after surgery. Analysis of demographic characteristics, comorbidities, previous surgeries, toumor characteristics and adjuvant therapy as was performed. Results. Most patients (64/100, 64%) expressed that LAR operation has strongly affected their QoSL, 32 patients reported the mild decrease in QoSL, while only 4 patients stated that did not experience any changes in QoSL. QoSL was assessed in 3 different periods of time: before the operation, 1 month after and 6 months after the operation (22,6±3.7 vs. 11.3±7,9 vs. 17,0±6.3; p<0.0001 respectively). The decreased QoSL one and six months after the surgery were significantly lower in patients with diagnosed hypertension and higher BMI (p=0.0283). Conclusions. Sexual disorders after LAR for rectal cancer are often underestimated and it is very important to be aware of them. In our study, it was determined that male sex, higher BMI and hypertension are related to impair of sexual dysfunction after LAR. We observed that the most severe complaints related to sexual activity occur one month after the procedure, after 6 months in most of the patients' sexual disorders were decreased approaching the initial state.
Źródło:
Polish Journal of Surgery; 2019, 91, 3; 21-26
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Innovative System for Evaluation and Rehabilitation of Human Imbalance
Nowatorski system do oceny i rehabilitacji układu równowagi
Autorzy:
Gawrońska, Anna
Zamysłowska-Szmytke, Ewa
Janc, Magdalena
Kotas, Rafal
Kamiński, Marek
Marciniak, Paweł
Tylman, Wojciech
Woźniak, Sebastian
Napieralski, Jan
Sakowicz, Bartosz
Pajor, Anna
Rosiak, Oskar
Puzio, Anna
Lucas-Brot, Weronika
Józefowicz-Korczyńska, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/27320345.pdf
Data publikacji:
2022-03-08
Wydawca:
Index Copernicus International
Tematy:
balance dysfunction
dizziness
mobile posturography
vertigo
vestibular rehabilitation
posturografia mobilna
rehabilitacja przedsionkowa
zaburzenia równowagi
zawroty głowy
Opis:
Introduction: Mobile posturography is based on wearable inertial sensors; it allows to test static stability (static posturography) and gait disturbances. Aim: The aim of this work was to present the results of research on the innovative MEDIPOST system used for diagnosis and rehabilitation of balance disorders. Material and methods: Fourteen articles published in influenced foreign journals were presented and discussed. The deve-lopment and construction of the device was preceded by a literature review and methodological work. The Dizziness Handi-cap Inventory (DHI) questionnaire was translated and validated. The methodology of posturography with head movements with a frequency of 0.3 Hz was also developed in the group with chronic vestibular disorders. Simultaneous measurements were performed (static posturogrphy vs. MEDIPOST) in the CTSIB-M (Modified Clinical Test of Sensory Interaction in Balance) test in healthy subjects and patients with unilateral peripheral dysfunction. Results: In the posturography with head movements the improvement of sensitivity (67 to 74%) and specificity (65 to 71%) was noted. In the CTSIB-M test the intraclass correlation coefficients for both methods were 0.9. The greatest differences between examinations were observed for the mean angular velocity in the tests on the foam (trials no. 3 and 4), in particular on the foam with eyes closed (trial no. 4 – sensitivity 86.4%, specificity 87.7%). Two functional tests were analyzed: the Swap Seats test and the 360 degree turn test. In the former, the results are studied from 6 sensors – 86% of the true positives and 73% of the true negatives for the fall/ no-fall group classification. The second test differentiates people with vestibular impairment and healthy people. It can be analyzed with 1 (sensitivity 80%) and 6 sensors (sensitivity 86%, specificity 84%). Currently, the MEDIPOST device is in the development and certification phase
Wstęp: Posturografia mobilna, oparta o czujniki sensoryczne montowane na tułowiu, pozwala na badanie stabilności statycznej (posturografia statyczna), a także na rejestracje zaburzeń podczas chodu. Cel: Celem tej pracy było przedstawienie wyników badań z zastosowaniem nowatorskiego systemu MEDIPOST, wykorzystanego do diagnostyki i rehabilitacji zaburzeń układu równowagi. Materiał i metody: Przedstawiono i omówiono 14 artykułów opublikowanych w zagranicznych czasopismach. Opracowanie i skonstruowanie urządzenia poprzedził przegląd literatury oraz prace metodyczne. Przetłumaczono i zwalidowano kwestionariusz niepełnosprawności Dizziness Handicap Inventory (DHI). Opracowano również metodykę posturografii z ruchami głowy o częstotliwości 0,3 Hz w grupie osób z przewlekłymi zawrotami głowy. Przeprowadzono jednoczasowo pomiary przy użyciu posturografii mobilnej ME-DIPOT i postruografii statycznej w teście MCTSIB (ang. Modified Clinical Test of Sensory Interaction in Balance) u osób zdrowych i chorych z jednostronną dysfunkcją obwodową układu równowagi. Wyniki: W badaniu posturografii z ruchami głowy stwierdzono poprawę czułości (z 67 do 74%) oraz swoistości (z 65 do 71%). W teście MCTSIB współczynniki korelacji wewnątrzklasowej dla obu metod (posturografia mobilna MEDIPOST vs statyczna) wynosiły 0,9. Największe różnice między badaniami zaobserwowano dla średniej prędkości kątowej środka ciężkości w próbach na piance (próba 3. i 4.), w szczególności zaś w próbach na piance z oczami zamkniętymi (próba 4. – czułość 86,4%, swoistość 87,7%). Dwa testy funkcjonalne poddano szczegółowej analizie: test przesiadania się między krzesłami (ang. Swap Seats) oraz test obrotu o 360 stopni. W pierwszym wyniki odczytywane są z 6 czujników – 86% wyników prawdziwie dodatnich i 73% wyników prawdziwie ujemnych dla klasyfikacji grup upadający/nieupadający. Drugi test pozwala różnicować osoby z uszkodzeniami przedsionkowymi i zdrowymi. Wynik może być analizowany z 1 (czułość 80%) i 6 czujników (czułość 86%, swoistość 84%). Aktualnie urządzenie MEDIPOST jest w fazie opracowywania i certyfikacji.
Źródło:
Polish Journal of Otolaryngology; 2022, 76, 3; 7-11
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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