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    Wyświetlanie 1-10 z 10
    Tytuł:
    Malignant transformation of the salivary gland pleomorphic adenoma in myoepithelial carcinoma – the report of two cases
    Autorzy:
    Szabelska, Paulina
    Rzepakowska, Anna
    Szczepankiewicz, Benedykt
    Niemczyk, Elżbieta
    Osuch-Wójcikiewicz, Ewa
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399613.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    salivary gland tumors
    carcinoma ex pleomorphic adenoma
    pleomorphic adenoma
    myoepithelial carcinoma
    Opis:
    A multiform adenoma is the most commonly diagnosed benign tumor of the salivary glands. In the majority of patients, surgical resection of the tumor with the adequate surrounding tissue of salivary gland allows for complete recovery. A small percentage of the cases is a recurring pleomorphic adenoma. Even more rarely the diagnosis of carcinoma ex pleomorphic adenoma is made. The study presents two clinical cases of the malignant transformation of pleomorphic adenoma into the myoepithelial carcinoma. The surgical treatment and additional radiotherapy were performed in both cases.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2019, 8, 1; 53-58
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Primary hyperparathyroidism on the example of a 33-year-old female patient with parathyroid adenoma
    Autorzy:
    Łach, Jarosław
    Dyaczyński, Michał
    Buczkowski, Krzysztof
    Powiązania:
    https://bibliotekanauki.pl/articles/1391700.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    parathyroid hyperactivity
    parathyroid adenoma
    kidney stones
    Opis:
    Parathyroid hyperactivity is the state of over-production and PTH secretion [1]. The most common cause of primary hyperparathyroidism is parathyriod adenoma - about 80% of cases, the remaining are parathyroid hyperplasia around 15%cases [2] [3], and in 1-5% of cases, cancer [2] [3] [4] [5]. The disease is diagnosed inabout 40 people in 100,000 [5] [6] [3] [7]. The most common cause of adenoma is the mutation in gene MEN 1. Less than 5% of cases are chronichyperparathyroidism, which is a component of the MEN 1 MEN 2a endocrine adenocarcinoma syndrome [1]. Excess PTH in the body leads to increased mobilization of calcium from the bones, and henceincreased osteolysis, what also increases the absorption of calcium from thedigestive system, as well as an increased amount of phosphate excretion in the urine. Clinical picture of the disease is multiform and often runs in a latent form. Most often the diseaseoccurs in the form of osteoporosis, chronic recurrent kidney stones, and is also commonpyelonephritis on the basis of urolithiasis. The disease may be accompanied by: dysphagia, abdominal pain, metallic taste in the mouth, persistent constipation. In addition, from the systemnervous: dizziness and headaches, disturbances of consciousness. Arrhythmia the form of additional contractions and paroxysmal tachycardia. Osteolysis, osteoporosis and pathological fractures [1]. The purpose of this article is to bring closer to the reader case of 33 years old woman with primary hyperparathyroidism on the adenoma.
    Źródło:
    Polish Journal of Surgery; 2020, 92, 3; 55-61
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pleomorphic adenoma - the results of a retrospective analysis of 104 patients treated at the Clinical Department of Cranio-Maxillofacial Surgery, Clinic of Otolaryngology and Laryngologic Oncology of the Military Institute of Medicine
    Autorzy:
    Korba, Michał
    Chloupek, Aldona
    Dąbrowski, Jarosław
    Piętka, Tomasz
    Domański, Wojciech
    Biernacka, Barbara
    Leśniak, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/1398512.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    pleomorphic adenoma
    tumor mixtus
    parotid gland
    parotidectomy
    Opis:
    Pleomorphic adenoma, also known as tumor mixtus, is one of the most common types of benign neoplasm of the salivary gland, which presents as a slow growing, painless tumor. Major salivary glands are the typical localization of this neoplasm. It rarely undergoes malignant transformation, however may recur locally post resection. In this study, we present the results of a retrospective analysis of 104 patients treated at the Clinical Department of Cranio-Maxillofacial Surgery, Clinic of Otolaryngology and Laryngologic Oncology of the Military Institute of Medicine between 2004 and 2015 due to pleomorphic adenoma. The study confirmed the parotid gland as the most common location of tumor mixtus. In some cases, the large size of the tumor and its location were the cause of life-threatening complications.
    Źródło:
    Polish Journal of Otolaryngology; 2017, 71, 4; 34-36
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mixed tumor of the parotid gland spreading into the cranial cavity
    Autorzy:
    Majszyk, Daniel
    Osuch-Wójcikiewicz, Ewa
    Czesak, Małgorzata
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1400063.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    pleomorphic adenoma
    benign mixed tumor
    intracranial invasion
    Opis:
    Pleomorphic adenoma is benign tumor of the salivary glands. It is the most common neoplasm occurring in salivary glands. Although it is a benign tumor, it should be treated as a clinically uncertain. In about half of the cases a blurred boundary between the tumor tissue and the parotid parenchyma can be observed. This tumor metastasize distant, even without malignant transformation. Malignant transformation of adenoma observed in 3-5% of cases. The aim of this study was to present the case of 75-year-old patient with recurrent mixed tumor spreading by continuity to the cranial cavity.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2017, 6, 1; 21-25
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Oxidative stress in proliferative lesions of parathyroid gland
    Autorzy:
    Deska, Mariusz
    Romuk, Ewa
    Segiet, Oliwia
    Polczyk, Joanna
    Buła, Grzegorz
    Gawrychowski, Jacek
    Powiązania:
    https://bibliotekanauki.pl/articles/1392364.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    oxidative stress
    primary hyperparathyroidism
    parathyroid hyperplasia
    parathyroid adenoma
    Opis:
    Background: Primary hyperparathyroidism (PHPT) is one of the most common endocrine disorders and defined as excessive secretion of parathormone. PHPT is a risk factor of several cardiovascular diseases, which could be caused by alterations in oxidant-antioxidant balance. Materials and methods: Blood serum collected from 52 consecutive patients with PHPT treated surgically constituted our study material, whereas 36 healthy volunteers were our control group. Oxidative stress was evaluated in both patients and control subjects by assessment of malondialdehyde (MDA) and lipid hydroperoxides (LHP). Antioxidants were evaluated by the measurement of superoxide dismutase (SOD), ceruloplasmin (CER), catalase (CAT), sulfhydryl (SH) groups, glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione transferase activity (GST) and glutathione reductase (GR). Moreover, total antioxidant capacity (TAC) and total oxidative status (TOS) were measured and oxidative stress index (OSI) was calculated. Results: OSI was increased in patients with PHPT when compared to normal controls, whereas TAC was lower in PHPT. The levels of CER, MnSOD, GR, SH groups and MDA were significantly decreased in PHPT. The levels of serum LHP, catalase and SOD were significantly higher in patients with PHPT than in healthy patients. The erythrocyte CAT activity and GST were significantly increased in patients after parathyroidectomy. The erythrocyte GR and GPx were up-regulated postoperatively, whereas SOD activity decreased. Conclusions: In PHPT there are several alterations in the balance between the production of reactive oxygen species and antioxidant defense system.
    Źródło:
    Polish Journal of Surgery; 2019, 91, 1; 29-34
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Przypadek gruczolaka oksyfilnego, wyjątkowo rzadkiego guza krtani, współistniejącego z rakiem płuca
    Autorzy:
    Kozakiewicz, J
    Teodorowicz, E
    Haczyńska-Partyka, A
    Myrcik, G
    Lange, D
    Szwabowicz, M
    Powiązania:
    https://bibliotekanauki.pl/articles/1398874.pdf
    Data publikacji:
    2007
    Wydawca:
    Index Copernicus International
    Tematy:
    adenoma oxyphillicum
    tumour of the larynx
    lung cancer
    Opis:
    There was presented an exstremely rare case of adenoma oxyphillicum of the larynx coexisting with the lung carcinoma. Diagnostical and medical conduct was throughly analyzed. It consisted such matters as detailed graphical examination, spliting of larynx, and radiotherapy and chemiotherapy of lung cancer. The authors want to call attention to limited use fullness of competent lungs X-ray in a-p projection in recognizing the early stadium of lung cancer.
    Źródło:
    Polish Journal of Otolaryngology; 2007, 61, 3; 311-314
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Review and characteristics of 585 salivary gland neoplasms from a tertiary hospital registered in the Polish National Major Salivary Gland Benign Tumors Registry over a period of 5 years: a prospective study
    Autorzy:
    Piwowarczyk, Krzysztof
    Bartkowiak, Ewelina
    Klimza, Hanna
    Greczka, Grażyna
    Wierzbicka, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/1397308.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    benign neoplasms
    characteristics
    pleomorphic adenoma
    registry
    salivary gland
    surgery
    Opis:
    Introduction: A Polish National Major Salivary Gland Benign Tumors Registry (SGR) is a report of benign salivary gland neoplasms (SGNs) from 26 different centres in Poland, introduced in 2014. The aim of this study is to analyze demographic characteristics and clinico-pathological factors of benign SGNs treated in large tertiary institutions and to determine possible correlations between selected variables. Material and method: Analysis of 585 patients recorded in SGR and operated on for SGNs in the Department of Otolaryngology and Laryngological Surgery, University of Medical Sciences, Poznań, Poland, over a 5-year period. Patient age, sex, occupation, place of residence, tumor location, size, histology, recurrence, facial nerve function after surgery, wound healing, surgery procedure, availability of pre-operative imaging examinations, fine-needle aspiration cytology (FNAC) results were analyzed. Results: 338 females and 247 males with a mean age of 53 years were operated on. In total, 96.2% of tumors originated from the parotid and 3.8% from the submandibular gland. The most frequent primary tumor diameter was 2–4 cm (59.5%) followed by <2 cm (29.2%) and >4 cm (8.4%). Tumors of over 4 cm were frequently removed by partial superficial parotidectomy, while those under 2 cm – by extracapsullar dissection (ECD). Pleomorphic adenomas (PA) were predominant (58.8%), followed by Warthin’s tumor (WT) – 37.1%. Patients with WT were on average 13.3 years older than patients with PA. Discussion: This research can be helpful to better understand the clinico-pathological features of SGNs. Long-termin hospital-based analysis is important for subsequent metaanalyses and comparisons with other centers. The reasons why not all patients’ data are reported to the national SGR should be further precisely analyzed.
    Źródło:
    Polish Journal of Otolaryngology; 2020, 74, 5; 1-6
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Giant pleomorphic adenoma of nasal cavities and paranasal sinuses
    Autorzy:
    Sroka, Paweł
    Okła, Sławomir
    Powiązania:
    https://bibliotekanauki.pl/articles/1399797.pdf
    Data publikacji:
    2018
    Wydawca:
    Index Copernicus International
    Tematy:
    Pleomorphic adenoma
    minor salivary glands
    paranasal sinuses
    nasal cavity
    Opis:
    Pleomorphic adenoma is benign tumor of the salivary glands. It is the most common neoplazm both major and minor salivary glands. Only in 1% of cases pleomorphic adenoma occur in the sinonasal cavities. The histopalogical wiew of pleomorphic adenomas originating from small salivary glands is different in higher cellularity and lower stromal component than those from major salivary glands. It is a benign tumor but it should be treated as a clinically uncertain. Malignant transformation of pleomorphic adenoma can occur in 2-10% of cases, The aim of this study was to present he case of 37-year-old patient with giant pleomorphic adenoma of the sinonasal cavities causing extensive destruction of sinuses and orbits walls.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2018, 7, 3; 15-21
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pleomorphic adenoma of the nasal cavity – a case report
    Gruczolak wielopostaciowy jamy nosowej – opis przypadku
    Autorzy:
    Frączek, Anna
    Szczygielska, Julia
    Majszyk, Daniel
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399249.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    benign tumors
    nasal cavity
    pleomorphic adenoma
    gruczolak wielopostaciowy
    jama nosowa
    nowotwór łagodny
    Opis:
    Introduction: Pleomorphic adenoma is a benign tumor which occurs most commonly in the major salivary glands. It is very rare in the nasal cavity and may be misdiagnosed because of its uncharacteristic clinical and histopathological manifestation. Case report: A case of a 42-year-old patient with pleomorphic adenoma on the lateral nasal wall has been presented. The tumor was accidentally found during FESS and septorhinoplasty. Initially, based on the histopathological examination of the obtained sample, there was a suspicion of adenoid cystic carcinoma. Later, the neoplasm was completely removed by the open septorhinoplasty and histopathological re-examination showed features of pleomorphic adenoma. Long term followup was necessary due to the potential risk of local recurrence.
    Wstęp: Gruczolak wielopostaciowy jest nowotworem łagodnym występującym najczęściej w śliniankach przyusznych. Bardzo rzadko pojawia się on w jamie nosa, co w połączeniu z jego niecharakterystycznym obrazem klinicznym i histopatologicznym stwarza ryzyko postawienia błędnego rozpoznania. Opis przypadku: Przedstawiono przypadek 42-letniego pacjenta z gruczolakiem wielopostaciowym na bocznej ścianie nosa. Guz został wykryty przypadkowo podczas endoskopowej operacji zatok i septoplastyki, a na podstawie badania histopatologicznego pobranego wycinka początkowo wysunięto przypuszczenie raka gruczołowo-torbielowatego. Guz został doszczętnie usunięty z dostępu do septorynoplastyki otwartej. W ponownym badaniu histopatologicznym wykazano cechy gruczolaka wielopostaciowego. Ze względu na ryzyko wznowy miejscowej, pacjent pozostał pod opieką poradni laryngologicznej.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2020, 9, 3; 47-51
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preoperative assessment of the risk of cavernous ICA injury in endoscopic transsphenoidal surgery
    Autorzy:
    Berger, Greta
    Łukasiewicz, Adam
    Grinevych, Vitalii
    Milewska, Anna Justyna
    Tarasów, Eugeniusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1391789.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    adenoma
    cavernous segment (C4) of internal carotid artery (ICA)
    computed tomography angiography (CTA)
    endoscopic endonasal transsphenoidal surgery
    magnetic resonance angiography (MRA)
    pituitary gland
    Opis:
    In endoscopic endonasal transsphenoidal procedures, ICA injury occurs in up to 3.8% [1]. The highest hazard of injury is in case of contact between the ICA and pituitary gland, during opening of the dura. Preoperative imaging, i.e. CTA, MRA, supports objectively intraoperative techniques of imaging. CTA as well as MRA are essential to access anatomic details in variability of cavernous segments of the ICA (C4 ICA). The aim of the study was to measure the space between Internal Carotid Arteries and distances between the pituitary gland and ICA on both sides. Anatomic relations between left and right ICAs were accessed on CTA (coronal scans) at levels: A – The most concave point of the C4–C5 bend; B – The most convex point of the C4 bend; C – The C4 posterior ascending portion. Distances between pituitary gland and ICAs were measured on both sides on MRA (axial scans): A’ – The most concave point of C4–C5 bend; B’ – The most convex point of the C4 bend. The Statistica 13 (StatSoft) software was used for the statistical analysis. The Mann-Whitney U test was applied to determine differences between the groups. To analyze the strength of correlations between the quantitative variables, Spearman’s rank correlation coefficients were calculated. The results were considered statistically significant at the level of P < 0.05. Distance reduction was shown between pituitary glands and cavernous segment (C4) of ICAs on both sides, which is related to age. This has impact on surgical planning and highlights the risk of intraoperative injury of ICAs.
    Źródło:
    Polish Journal of Surgery; 2020, 92, 2; 1-7
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-10 z 10

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