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Wyszukujesz frazę "biofunctionalization" wg kryterium: Temat


Wyświetlanie 1-2 z 2
Tytuł:
Vascular smooth muscle cells in cultures on biofunctionalized cellulose-based scaffolds
Autorzy:
Novotna, K.
Bacakova, L.
Lisa, V.
Havelka, P.
Sopuch, T.
Klepetar, J.
Powiązania:
https://bibliotekanauki.pl/articles/285170.pdf
Data publikacji:
2009
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
oxidized cellulose
tissue engineering
biofunctionalization
chitosan
arginine
vascular smooth muscle cells
Opis:
Viscose, dialdehyde cellulose and oxidized 6-car-boxycellulose with 2.1 or 6.6wt.% of –COOH groups were prepared. The materials were subsequently functionalized with arginine or chitosan. Both unmodified and biofunctionalized materials were seeded with vascular smooth muscle cells. The morphology of the adhered cells indicated that oxidized 6-carbo-xycellulose with 2.1% content of –COOH groups was the most appropriate of all tested materials for potential use in tissue engineering. The shape of the cells on this material was elongated, which demonstrates adequate adhesion and viability of the cells, while the morphology of the cells on other tested materials was spherical. Moreover, the stability of 6-carboxycellulo-se with 2.1wt.% of –COOH groups in the cell culture environment was optimal, with a tendency to degrade slowly with time. The highest stability was found on the viscose samples, whereas there was very low stability on oxidized 6-carboxycellulose with 6.6 wt. % of –COOH groups, and also on dialdehyde cellulose. Functionalization with arginine or chitosan increased the number of adhered cells on the materials, but not markedly. We did not obtain a significant elevation of the cell population densities with time on the tested samples. These results suggest the possibility of using a cellulose-based material in such tissue engineering applications, where high proliferation activity of cells is not convenient, e.g. reconstruction of the smooth mu-scle cell layer in bioartificial vascular replacements.
Źródło:
Engineering of Biomaterials; 2009, 12, no. 89-91; 21-24
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Micro- and nanopatterned surfaces for guided adhesion, growth and phenotypic maturation of cells
Autorzy:
Bacakova, L.
Filova, E.
Grausova, L.
Vandrovcova, M.
Parizek, M.
Novotna, K.
Svorcik, V.
Vacik, J.
Rypacek, F.
Kromka, A.
Heitz, J.
Shard, A.
Powiązania:
https://bibliotekanauki.pl/articles/284586.pdf
Data publikacji:
2009
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
surface patterning
microstructure
nanostructure
biofunctionalization
endothelial cells
vascular smooth muscle cells
bone cells
Opis:
Micropatterned surfaces were created by UV light-irradiation of polytetrafluoroethylene through a metallic mask, by successive plasma polymerization of acrylic acid and 1,7-octadiene, or by creation of prominences and grooves by deposition of fullerenes C60 through a metallic mask. All these surface types were capable of inducing regionally-selective adhesion, proliferation and phenotypic maturation of vascular endothelial cells, vascular smooth muscle cells or human bone-derived MG 63 cells. Nanopatterned surfaces created by tethering GRGDSG oligopeptides through polyethylene oxide chains on a polymeric surface promoted spreading, formation of focal adhesion plaques and DNA synthesis in vascular smooth muscle cells. Surfaces nanopatterned with nanocrystalline diamond gave good support for the adhesion, growth and metabolic activity of osteoblast-like MG 63 cells.
Źródło:
Engineering of Biomaterials; 2009, 12, no. 89-91; 18-21
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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