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Wyszukujesz frazę "pyrimidine" wg kryterium: Temat

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    Wyświetlanie 1-5 z 5
    Tytuł:
    Synthesis characterization and antimicrobial activity of ethyl-4-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-thioxopyrimidine-5-carboxylate
    Autorzy:
    Pasupathi, M.
    Santhi, N.
    Powiązania:
    https://bibliotekanauki.pl/articles/1076112.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    MIC
    antimicrobial
    mesoporous
    pyrimidine
    Opis:
    Heteroatoms like nitrogen, sulfur, and oxygen containing biologically active ethyl 4-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-thioxopyrimidine-5-carboxylate was synthesized from 2,4-dichloro benzaldehyde, acetoacetic ester and thiourea using AlTiTUD-1 as a catalyst. The synthesized compound was characterized by FT-IR, 1H and 13C NMR spectral values. The compound possesses good antimicrobial activity is determined by well diffusion method against gram positive, gram negative and fungal species. The minimum inhibitory concentration value of the compound was determined by broth dilution method.
    Źródło:
    World Scientific News; 2019, 117; 212-220
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and characterization of 2-(methylthio)-6-oxo-6H-chromeno[3,4-e]pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives
    Autorzy:
    Ajudiya, Yogesh M.
    Babariya, Jayesh S.
    Upadhyay, J. J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1070890.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Pyrazolo pyrimidine
    Schiff base
    coumarine
    Opis:
    Some new 2-(methylthio)-6-oxo-6H-chromeno[3,4-e]pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives Having coumarine nucleus were synthesized by novel synthetic rout from 4-chloro 3-carbaldehyde coumarine derivatives and previously prepared 5-amino-3-(methylthio)-1H-pyrazole-4-carbonitrile using methanol as a solvent and catalytic amount of glacial acetic acid. All the synthesised libraries were characterized by IR, NMR and mass spectral analysis.
    Źródło:
    World Scientific News; 2019, 123; 258-264
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ultrasonic velocity, density and viscosity measurement of pyrimidine derivatives in 1,4-dioxane and DMF at various temperatures
    Autorzy:
    Baluja, Shipra
    Nandha, Kajal
    Ramavat, Paras
    Powiązania:
    https://bibliotekanauki.pl/articles/1190220.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Pyrimidine derivatives
    ultrasonic velocity
    viscometry
    molecular interaction
    apparent molar compressibility
    Opis:
    The estimation of density, viscosity and ultrasonic velocity of solution of pyrimidine derivatives in 1,4-dioxane and N,N-dimethylformamide was carried out as functions of concentration (0.01 to 0.1 M) and temperature (298.15 to 318.15 K). Some acoustical and apparent parameters such as acoustical impedance (Z), intermolecular free length (Lf), adiabatic compressibility (κs), molar compressibility (W), Vander Waals constant (b), relaxation strength (r), internal pressure (π), apparent molar compressibility (fk), apparent molar volume (fv) etc., have been evaluated using experimental data of ultrasonic velocity (U), density (ρ) and viscosity (η). The characterization of these synthesized compounds was done by IR, 1H NMR and mass spectral data.
    Źródło:
    World Scientific News; 2016, 44; 257-278
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Solubility of pyrimidine derivatives in different organic solvents at different temperatures
    Autorzy:
    Baluja, Shipra
    Powiązania:
    https://bibliotekanauki.pl/articles/1190176.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    pyrimidine derivatives
    Apelblat equation
    Buchowski-Ksiazack λh equation
    Gibb׳s energy
    Opis:
    The objective of this study was to measure and correlate the solubility of pyrimidine derivatives in five different solvents namely chloroform, N,N-dimethylformamide, tetrahydrofuran, 1,4-dioxane and ethyl acetate from 298.15 to 328.15 K under atmospheric pressure of 0.1 MPa using gravimetric method. The characterization of all the synthesized compounds was done by IR, NMR and mass spectra. The modified Apelblat and Buchowski-Ksiazczak λh equations were used to correlate the experimental solubility data. Using Van’t Hoff and Gibb’s equations, some thermodynamic parameters such as Gibb’s free energy, enthalpy and entropy of dissolution were evaluated from solubility data. It is found that solubility increases with temperature.
    Źródło:
    World Scientific News; 2016, 44; 13-34
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis and characterization of diversely substituted pyrimidine-3-carboxamide and their antimicrobial evaluation
    Autorzy:
    Senjani, Hardik K.
    Joshi, H. D.
    Powiązania:
    https://bibliotekanauki.pl/articles/1031771.pdf
    Data publikacji:
    2020
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    1-4-dihydropyrimidine
    analgesic
    anti-inflammatory
    antibacterial
    anticonvulsant
    antifungal
    antimicrobial
    antituberculosis
    antitumor
    biginalli
    dihydropyrimidine
    insecticidal
    multi-component reaction
    pyrimidine
    Opis:
    Pyrimidine related fused heterocycles are attracted to every chemist during the last decade for their biological and chemotherapeutic importance. Pyrimidine derivatives play a vital role in their broad spectrum of biological activities including antituberculosis, anticonvulsant, anti-inflammatory, insecticidal, antifungal, analgesic, and antitumor properties and there of interest as potential bioactive molecules. The nitrogen-containing fragment may be an amidine, urea, thiourea, or guanidine, and adamantine homologs and aromatic aldehyde serve as an excellent illustrative example in that it readily undergoes as Biginali MCRs reaction. Pyrimidines and their derivatives are considered to be important for drugs and agricultural chemicals. Pyrimidine derivatives possess several interesting biological activities. Pyrimidine is a basic nucleus in DNA & RNA, it is associated with diverse biological activities so, we have designed and prepared a novel highly functionalized pyrimidine library of 1,4 DHP and DHPM via a one-pot multi-component (MCRs) synthesis and we screened for antimicrobial activity against various strains.
    Źródło:
    World Scientific News; 2020, 150; 39-77
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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