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Wyświetlanie 1-8 z 8
Tytuł:
XI Dzień Kliniczny Parazytologii Lekarskiej
XI Clinical Day of the Medical Parasitology
XI Klinicheskijj Den Medicinskojj Parazitologii
Autorzy:
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2176434.pdf
Data publikacji:
1973
Wydawca:
Polskie Towarzystwo Parazytologiczne
Źródło:
Wiadomości Parazytologiczne; 1973, 19, 2; 244-247
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zdolność dezaminacji aminokwasów przez wybrane gatunki grzybów
THE CAPABILITY OF DISSOCIATION OF AMINOACIDS BY SELECTED STRAINS OF FUNGI
Autorzy:
Białasiewicz, D.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2147943.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
gatunki grzybow
grzyby
Candida
rozklad aminokwasow
dezaminacja
parazytologia
Trichosporon
Geotrichum
aminokwasy
Opis:
We have studied the capability of dissociation of 22 L-form aminoacids by 27 strains of fungi belonging to species: Candida, Cryptococcus, Geotrichum, Rhodotorula, Saccharomyces, Trichosporon. Fungal strains were cultured on agar medium with phenyl red and studied aminoacid. Disamination of an aminoacid by a fungus resulted in alkalisation of the medium and change of its colour from yellow to pink. Strains from genus Trichosporon and Geotrichum decomposed the most aminoacids (15-16), while fungi from genus Candida decomposed less aminoacid (1-8). Strains form species Candida famata, C. kefyr, C. lambica. C. rugosa, C. neoformans, R. mucilaginosa and S. cerevisiae did not show any ability to desaminate any of the 22 aminoacids used in the study. Aminoacids most frequently disaminated by the studied strains of fungi included acidic aliphatic aminoacids and their amides: L-aspartic acid, L-asparagine, L-glutaminic acid, L-glutamine and neutral aliphatic aminoacids: L-glycin, L-alanine, L-serine. Aromatic and sulphur aminoacids (L-cysteine, L-cystine) were not decomposed by the studied fungal strains.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 3; 339-344
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:
It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:
Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktualne możliwości stosowania leków przeciwgrzybiczych w niektórych chorobach skóry
Current possibilities of using antimycotic drugs in the treatment of various skin disorders.
Autorzy:
Choczaj-Kukuła, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2146442.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
choroby skory
grzybica skory
leki przeciwgrzybicze
stosowanie
Opis:
The purpose of this article is to review the literature data on the therapeutic protocols and the results of using some antimycotics in different skin diseases. In addition to the antimycotic action, particular antifungal drugs such as itraconazole, ketoconazole and terbinafine exhibit anti-inflammatory activity by inhibiting the synthesis of 5-lipooxygenase metabolites. As these metabolites are involved in a number of inflammatory and immunoreactive processes the dual action of the drugs may be suitably exploited in the treatment of some skin diseases which are otherwise difficult to cure. Another rationale for the use of antimycotics in certain skin disorders is their action against Malassezia. It has been recently demonstrated that Malassezia, present as a commensal in the epidermis, may play an important role in inducing certain inflammatory processes by stimulating cytokine production by keratinocytes. The antimycotics proved to be useful in the therapy of the following skin conditions: seborrheic dermatitis, Malassezia folliculitis, perioral dermatitis and papulopustular rosacea, as well as adult atopic dermatitis. The use of antimycotic drugs in amicrobial palmoplantar pustulosis and sebopsoriasis remains controversial. These medications are also an alternative in the treatment of leishmaniosis.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 2; 125-133
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Grzyby u chorych na cukrzycę typu 2: prewalencja, gatunki wyizolowanych szczepów
Fungi in patients with diabetes mellitus type 2: prevalence, species of isolated strains.
Autorzy:
Maciejewska, A.
Jaskółowska, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2146446.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
gatunki grzybow
grzyby
choroby czlowieka
cukrzyca
szczepy grzybow
Opis:
In 77 diabetic patients the detection of fungi was carried out in the oral cavity, digestive tract, genital organs and skin lesions. Patient age ranged from 39 to 82 years, with the Body Mass Index (BMI) from 22 to the highest values of 46.5. Diabetes control was assessed by determination of the glucose level in serum after overnight fasting and after lunch, as well as by determination of the НБА | с level. Fungi were diagnosed in 61 patients (79.6%). The total of 111 fungal strains were isolated in 319 cultures evaluated from 12 biological materials. Fungal strains were detected in the highest percentage in oral cavity (77.9%), in the lower percentage in anus (33.8%), vagina discharge (11.6%) and the region of vulva (14.3%). Fungi were observed in one focus — exclusively in the oral cavity — in 28 (36.4%) patients, whereas they occurred in multifocal infections in 33 (42.9%) patients. The isolated fungal strains were classified into 4 genera (Candida, Saccharomyces, Trichosporon, Aspergillus) and 12 species. The most frequently detected fungi were C. albicans (55.2%), followed by C. glabrata (12.4%), C parapsilosis (10.5%) and С. tropicalis (9.5%). Relatively low percentage of fungi identified in vagina was associated, among others, with the fact that most of the female patients with diabetes were at the postmenopausal period. In all the patients in whom fungi were isolated from the vagina contents, these fungi were also found in other ontocenoses. The increase in percentage of fungal strains from genera other than Candida in patients with a higher risk is of clinical importance, as some of them are resistant in vitro to azole derivatives e.g. fluconazole. The digestive tract is thought to be the most frequent fungal habitat. A considerable prevalence of fungi, multifocal infections, particularly related to oral cavity and anus, and occurrence of high percentage of strains different from C. albicans species of Candida genus in female patients with type 2 diabetes indicate the necessity of the special mode of diagnostic and therapeutic management.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 2; 163-170
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena niektórych danych klinicznych u pacjentów z łupieżem pstrym
Evaluation of some clinic data in patients with tinea versicolor
Autorzy:
Kwaśniewska, J.
Moruś-Urbańska, E.
Jaskółowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2143476.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Malassezia
grzybice
grzyby
lupiez
lupiez pstry
ocena kliniczna
pacjenci
Opis:
Fungi from Malassezia species may be a component of human and animal skin onthocenosis but also may cause general mycoses in patients from high risk groups. The aim of study was the evaluation of some clinic data in patients with tinea versicolor, who entered to Department of Biology and Medical Parasitology, Centre for Treatment of Parasitic Diseases and Mycoses, Medical University of Lodz. Forty four patients with tinea versicolor were examined. Localization and number of skin lesions as well as eventually risk factor were examined. In all patients mycological examine was done; morphotic elements of fungi in direct and stained slides were found, cultures on solid medium with oil olive were done. In Wood light fluorescence of changed skin was observed. The most incidence of tinea versicolor was observed in young persons to compare with to another age groups. The most frequently localization of clinical lesions concerned back skin, back and chest. In women – to compare with to male patients – clinical lesions on back skin were significantly more frequent. The only one factor was conducived to infection – it was a seborrhea of the skin, observed mainly in patients from the youngest age group.
Źródło:
Wiadomości Parazytologiczne; 2010, 56, 4; 323-327
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Udział grzybów w etiopatogenezie trudno gojących się ran po zabiegach ortopedycznych
The role of fungi in etiopathogenesis of delayed orthopaedic wound healing.
Autorzy:
Raczyńska-Witońska, G.
Kwaśniewska, J.
Witoński, D.
Powiązania:
https://bibliotekanauki.pl/articles/2146447.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
Candida albicans
grzyby
gojenie ran
zakazenia grzybicze
Candida
zabiegi chirurgiczne
ortopedia
rany pooperacyjne
etiopatogeneza
Opis:
Mycological investigations were carried out in 20 patients due to the delayed wound healing, following orthopaedic surgery at the Department of Orthopaedics, Medical University of Łódź. The material samples for fungal assessment were taken from the wound, surrounding skin and oral cavity. In all patients, the fungi were isolated at least from one ontocenosis; from the wound in 40.0% of subjects studied, from the wound-surrounding skin in 55.0% and from the oral cavity in 85.0%. It should be emphasized that the occurrence of fungi was more frequently observed simultaneously in two or three ontocenoses (70.0%) than in one (30.0%). Unifocal infection was found only in the oral cavity, while the presence of fungi in the wound was accompanied by their appearance in the region of wound-surrounding skin and/or in the oral cavity.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 2; 171-175
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości przeciwrzęsistkowe pochodnych eterów zawierających reszty aminowe i chlorowcoaryloalkilowe
Trichomonacidal properties of the derivatives of ethers containing amine and halogenaryloalkyl groups
Autorzy:
Białasiewicz, D.
Kotełko, B.
Kurnatowska, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2152441.pdf
Data publikacji:
1990
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia lekarska
rzesistek pochwowy
Trichomonas vaginalis
srodki lecznicze
pochodne eterow
reszty aminowe
reszty chlorowcoaryloalkilowe
substancje biologicznie czynne
zwiazki organiczne
dzialanie przeciwpasozytnicze
aktywnosc rzesistkobojcza
Opis:
The trichomonacidal activity in vitro of 6 new derivatives of theirs containing amine and halogenaryloalkyl groups in comparison with metronidazole, ornidazole and tinidazole has been examined. For all the examined compounds curves of action were obtained after 30 min. and lethal concentrations for 50% population (CL₅₀) of three strains of T. vaginalis used for experiments were calculated. The trichomonacidal action of the following compounds was especialy strong: 2-/1-methylpiperazin-4-yl/ethyl-4-chlorbenzhydryl ether dihydrochloride and 2-/1-benzylperhydro-1,4-diazepin-4-yl/ethyl 2,4-dichlorbenzyl ether dihydrochloride. The trichomonacidal action of these compounds was several times stronger than that of metronidazole and tinidazole.
Źródło:
Wiadomości Parazytologiczne; 1990, 36, 5-6; 281-285
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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