- Tytuł:
-
Monitorowanie metabolizmu komórkowego za pomocą metody spektroskopii NMR
Monitoring of cellular metabolism by NMR spectroskopy - Autorzy:
-
Pudełko-Malik, Natalia
Sapeta, Monika
Młynarz, Piotr - Powiązania:
- https://bibliotekanauki.pl/articles/2200583.pdf
- Data publikacji:
- 2022
- Wydawca:
- Polskie Towarzystwo Chemiczne
- Tematy:
-
metabolomics
nuclear magnetic resonance (NMR)
cell line
metabolomika
NMR
linia komórkowa - Opis:
- Metabolomics approaches allow systematic identification and quantitation of all metabolites in biological samples analyzes. As already known metabolism is directly or indirectly related to every aspect of cell function, therefore a careful observation of every changes taking place in metabolism, for example endogenous biochemical reaction products, reflectsthe phenotype of any living cell. Monitoring the metabolite profiles using metabolomics technologies, especially nuclear magnetic resonance (NMR) spectroscopy based on cell culture, allows us to evaluate drug efficiency and outcome of experimental therapy, and most importantly, it allows us to monitor the reaction of the model cell lines to a given treatment. The continued development of metabolomic approaches, e.g. analytical technique, or chemometric software, will accelerate the widespread use of metabolomics not only in the clinical field but also in different biological fields. This work presents a use of nuclear magnetic resonance to characterize and understand the cellular metabolome in a wide range of pathophysiological and clinical contexts.
- Źródło:
-
Wiadomości Chemiczne; 2022, 76, 5-6; 323--333
0043-5104
2300-0295 - Pojawia się w:
- Wiadomości Chemiczne
- Dostawca treści:
- Biblioteka Nauki
Artykuł