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    Wyświetlanie 1-5 z 5
    Tytuł:
    Electrolytic method for obtaining porous chitosan structures with hydroxyapatit
    Autorzy:
    Tylman, Michał
    Mucha, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1035430.pdf
    Data publikacji:
    2011
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    HAp
    chitosan
    electrolysis
    electrolytic conductivity
    Opis:
    The aim of this study was to develop a preparation method of porous chitosan structures, in the electrolysis of the chitosan solution in acetic acid. Chitosan in aqueous acetic acid is a polyelectrolyte. During the constant flow of electric current through this system, pure chitosan begins to accumulate on an anode, in the form of porous hydrogel layers. The addition of hydroxyapatite (HAp) to the electrolyte enhances the process and allows for obtaining spatially arranged complex structures of chitosan.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2011, 16; 5-14
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Porous chitosan structures for medical applications
    Autorzy:
    Tylman, Michał
    Mucha, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1035545.pdf
    Data publikacji:
    2010
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan scaffolds
    lyophilization
    tissue engineering
    Opis:
    The aim of the study was to develop preparation methods of porous chitosan structures and to investigate their morphological properties as well as the kinetics of model substance release (salicylic acid). Chitosan scaffolds were generated using the liophylisation method and the systems obtained were saturated with hydroxyapatite and salicylic acid. Microscopic investigations (optical and electron microscopy) were carried out to examine the morphology of structures and water vapour sorption isotherms were determined to define the influence of hydroxyapatite on the system sorption ability. Additionally, the kinetic curve for the model substance release process (the process of the 1st order) was determined.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2010, 15; 97-106
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preparation and characterization of a new generation of chitosan hydrogels containing pyrimidine ribonucleotides
    Autorzy:
    Pieklarz, Katarzyna
    Tylman, Michał
    Modrzejewska, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1034023.pdf
    Data publikacji:
    2020
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    biomaterial
    chitosan
    hydrogel
    neural tissue regeneration
    Opis:
    Damage to the nervous system, in particular spinal cord injuries, is a burden for the patient and is usually the cause of irreversible disability. The progress observed in the last decade in the fields of biology, biomaterial engineering and neurosurgery has created new treatment solutions while preventing further neurodegenerative processes. The most important research is focused on the implementation of polymer structures in clinical practice, especially chitosan hydrogels, which are the scaffolds for regenerating axons. This article presents a new generation of biomaterials that have the ability to gel in response to temperature changes; they are intended for injectable scaffolds for nerve cell cultures. Two types of hydrogels were prepared based on chitosan lactate and chitosan chloride using uridine 5’-monophosphate disodium salt. The structure of the systems was observed under a scanning electron microscope and examined using Fourier transform infrared spectroscopy. In addition, thermal properties were tested using differential scanning calorimetry.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 192-200
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Applications of chitosan–graphene oxide nanocomposites in medical science: a review
    Autorzy:
    Pieklarz, Katarzyna
    Tylman, Michał
    Modrzejewska, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1034405.pdf
    Data publikacji:
    2018
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    biopolymers
    chitosan
    graphene
    graphene oxide
    nanomedicine
    Opis:
    Combinations of biopolymers with nanostructured carbon materials have been the subject of interest of many scientists in recent years. Particularly significant are nanocomposites made of chitosan, which is a linear aminopolysaccharide obtained in the process of deacetylation of chitin, and graphene oxide (GO). These systems, due to the atypical properties of both components such as non-toxicity, biocompatibility with human tissues and organs as well as bacteriostaticity, are characterised by a wide range of biomedical applications. They may be used in emergency medicine as dressing materials which accelerate wound healing, as well as carriers of drugs/genes and biological macromolecules, for example proteins, peptides and nucleic acids. In addition, CS-GO systems can potentially be used in regenerative medicine as scaffolds for cell culture. For this reason, the current publication presents the possibilities of the application of chitosan–graphene oxide nanocomposites in medicine considering the characteristics of the system components.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2018, 23; 5-24
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural and biological characteristics of self-organising chitosan hydrogels
    Autorzy:
    Pieklarz, Katarzyna
    Tylman, Michał
    Modrzejewska, Zofia
    Galita, Grzegorz
    Majsterek, Ireneusz
    Powiązania:
    https://bibliotekanauki.pl/articles/2131528.pdf
    Data publikacji:
    2021
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    biomaterials
    chitosan
    cytotoxicity
    self-organising hydrogels
    structural properties
    tissue engineering
    Opis:
    Creating innovative methods of treatment and regeneration of damaged tissues or organs is a key challenge of the twenty-first century. The aim of this study was to determine the possibility of producing and characterising the properties of self-organising chitosan hydrogels prepared with the use of chitosan lactate/chloride and disodium hydrogen phosphate dodecahydrate as a cross-linking agent. The structure and supramolecular architecture of the biomaterials were evaluated by Fourier-transform infrared spectroscopy and polarised optical microscopy. Biological studies assessed cytotoxicity by contact with a human colon adenocarcinoma cell line. The colourimetric resazurin assay showed that the obtained chitosan hydrogels are non-cytotoxic materials. Thus, self-organising biomaterials hold great promise for application in tissue engineering.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2021, 26; 191-199
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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