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    Wyświetlanie 1-12 z 12
    Tytuł:
    Determination of polymorphism of IS-1311 sequence in Mycobacterium avium subspecies paratuberculosis strains isolated from milk samples
    Autorzy:
    Szteyn, J.
    Bednarko-Młynarczyk, E.
    K. Liedke
    Wiszniewska-Łaszczych, A.
    Wojtacka, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087864.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Mycobacterium avium subsp. paratuberculosis
    milk
    IS-1311 polymorphism
    Źródło:
    Polish Journal of Veterinary Sciences; 2017, 4; 827-829
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association of polymorphism within LTF gene promoter with lactoferrin concentration in milk of Holstein cows
    Autorzy:
    Zabolewicz, T.
    Barcewicz, M.
    Brym, P.
    Puckowska, P.
    Kaminski, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/31378.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    This study analyzed the association between single nucleotide polymorphism (A/C) in position -28 located in the TATA box of LTF gene and the lactoferrin concentration in bovine milk secreted by healthy and infected udders. Out of 241, 69 cows were selected into the experimental group and were divided into 3 groups according to mean value of somatic cell count (SCC): I <180 000 cells/mL, II: 180 000 - 350 000 cells/mL and III > 350 000 cells/mL. In each SCC group, three LTF genotypes: AA, AC and CC were identified by PCR-SSCP method. A total of 604 milk samples were collected monthly and lactoferrin concentration was measured by ELISA. The 1-way ANOVA within SCC groups was performed to estimate association of -28 A/C genotypes with mean lactoferrin concentration per lactation. In the group of healthy cows (<180 000 cells/mL) LTF concentration in milk cows with the AA genotype (107.58 ± 17.92 μg/mL) was significantly higher than in homozygotes CC (52.09 ± 19.01 μg/mL). Unexpectedly, in cows with elevated SCC (>350 000 cells/mL) we observed a significant opposite relationship (207.21 ± 28.50 in CC vs 115.0 ± 28.6 μg/mL in AA). We hypothesized that a promoter with allele C, which cannot be recognized as a TATA sequence is becoming more accessible for other transcription factors, which may induce alternative LTF gene expression. We assume that our results demonstrate a very interesting effect of differential gene expression depending on polymorphism in a key regulatory motif (TATA box) and also on the health status of mammary tissues.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polymorphism and expression of the tumor necrosis factor receptor II gene in cows infected with the bovine leukemia virus
    Autorzy:
    Stachura, A.
    Brym, P.
    Bojarojc-Nosowicz, B.
    Kaczmarczyk, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/32553.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    A single T>C nucleotide polymorphism (rs42686850) of bovine tumor necrosis factor receptor type II gene (TNF-RII) is located within a sequence with allele-specific affinity to bind E2F transcription factors, considered pivotal in the regulation of cell cycle and cell proliferation. The objective of the study was to determine the effect of this SNP and BLV infection on the TNF-RII gene expression at the mRNA and protein levels in peripheral blood mononuclear cells (PBMC). We noted that analyzed TNF-RII gene polymorphism influenced the expression of the TNF-RII gene at the mRNA level but only in BLV-positive cows. Concurrently, no statistically significant association was found between gene polymorphism and TNF-RII expression at the protein level. However, we found a significant effect of BLV infection status on the amount of TNF-RII mRNA and the percentage of PBMC expressing TNF-RII. These results show an unclear effect of considered T>C polymorphism on TNF-RII gene expression in bovine leukocytes and they suggest the involvement of BLV in modifying the TNF-RII expression in BLV-infected cows potentially implying the EBL (Enzootic Bovine Leukosis) associated pathogenesis.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Single nucleotide polymorphism within arylsulfatase D gene (ARSD) is associated with selected kinematic parameters of sperm motility in Holstein-Friesian bulls
    Autorzy:
    Hering, D.
    Lecewicz, M.
    Kordan, W.
    Kaminski, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/30896.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of the study was to find out whether the single nucleotide polymorphism (SNP) within arylsulfatase D (ARSD) gene is associated with kinematic parameters of sperm motility in Holstein- Friesian bulls. 367 Holstein-Friesian bulls kept in one AI center were included in the study. Point mutation C/T at position 139037255 on chromosome X (rs42207167) was identified by PCR-RFLP method (Pflm I). Significant associations were found between ARSD genotypes and CASA-derived sperm motility parameters: average TM (Total Motility), average VSL (Straight Velocity), average VCL (Curvilinear Velocity) and for fraction of sperms showing progressive motility (a) of sperms (VSLa, VCLa and BCFa -Beat Cross Frequency). Most significant differences were observed between alternative homozygotes (CC vs TT). Our results suggest new role of arylsulfatase D gene as being involved in sperm motility.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    SNP panel for evaluation of genetic variability and relationship in roe deer (Capreolus capreolus)
    Autorzy:
    Oleński, K.
    Zalewski, D.
    Kamiński, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/16647455.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    Capreolus capreolus
    genetic diversity
    roe deer
    Single Nucleotide Polymorphism marker
    Opis:
    Blood samples from forty-six roe deer (Capreolus capreolus) acquired during officially approved hunting in six hunting divisions throughout Poland were used to isolate the genomic DNA. All individuals were genotyped by MD_Bovine BeadChip (Illumina) for 46.750 Single Nucleotide Polymorphism (SNP) markers. SNPs of inappropriate clusters, with a marker call rate lower than 90% and with a minor allele frequency (MAF) lower than 0.01, located on sex chromosomes and mitochondrial DNA, were removed. Altogether, 21.033 SNP markers were included for further analysis. Observed and expected heterozygosity amounted to 0.098 and 0.119, respectively. Among 21.033 markers, a panel of 148 SNPs were selected for relationship analysis. They were unlinked and had a MAF higher than 0.2. This set of SNPs showed a probability of parentage exclusion of 1.29x10 -6 and 2.37x10 -19 for one, and two known parents, respectively. The probability of identity was estimated at 1.8x10 -40. The probabilities obtained in this study are sufficient for the monitoring and effective management of the genetic diversity of roe deer in Poland and is a cost-effective complementary tool for forensic applications.
    Źródło:
    Polish Journal of Veterinary Sciences; 2023, 26, 1; 29-37
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the Bovine Leukemia Virus
    Autorzy:
    Bojarojc-Nosowicz, B.
    Kaczmarczyk, E.
    Stachura, A.
    Kotkiewicz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31844.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The objective of this study was to describe and compare the genetic structure (TNF-α-position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-α-824A/G). The genetic equilibrium in these herds was preserved, but a tendency to increased frequency of G/G homozygotes was found. The genetic structure of the healthy herd differed considerably from that of leukemic herds.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of splicing mutation within the lysophosphatidic acid receptor 1 gene (LPAR1) on semen quality in Holstein-Friesian bulls
    Autorzy:
    Kamiński, S.
    Hering, D.M.
    Kordan, W.
    Lecewicz, M.
    Sazanov, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087732.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bull
    sperm
    quality
    LPAR1
    polymorphism
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 2; 419-421
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isolation and molecular typing of Mycobacterium avium subsp. paratuberculosis from faeces of dairy cows
    Autorzy:
    Szteyn, J.
    Liedtke, K.
    Wiszniewska-Łaszczych, A.
    Wysok, B.
    Wojtacka, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087298.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Mycobacterium avium subsp. paratuberculosis (MAP)
    insertion sequences polymorphism
    C-type
    S-type
    Źródło:
    Polish Journal of Veterinary Sciences; 2020, 23, 3; 415-422
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Tumor necrosis factor - alpha (TNFalpha) gene polymorphism and expression of membrane - bound TNFalpha protein on CD11bplus and IgMplus cells in cows naturally infected with bovine leukemia virus
    Autorzy:
    Bojarojc-Nosowicz, B.
    Kaczmarczyk, E.
    Stachura, A.
    Kubinska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31645.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of this study was to determine whether SNP at position -824 (promoter region) of the TNFα gene significantly differentiates the size of IgM+, CD5+ and CD11b+ cell subpopulations and affects the expression of membrane-bound TNFα protein (mTNFα) on these cells and their susceptibility to BLV infections. In this study, significant differences were determined for the first time between TNFα genotypes and the percentage of cells with the CD11b+TNFα+p24+ immunophenotype. Furthermore, greater expansion of lymphocytes with the IgM+TNFα+p24+ immunophenotype was reported in cows with the G/G genotype than in A/A homozygotes. Cells with the above immunophenotype were more frequently observed in cows with persistent leukocytosis than in aleukemic cattle. Our results suggest that polymorphism of the TNFα -824 A>G gene and mTNFα protein expression play an important role in the pathogenesis of enzootic bovine leukosis.
    Źródło:
    Polish Journal of Veterinary Sciences; 2015, 18, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Missense mutation within cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with selected parameters of the frozen-thawed spermin Holstein-Friesian bulls
    Autorzy:
    Kaminski, S.
    Hering, D.M.
    Kordan, W.
    Lecewicz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087549.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bull
    sperm
    polymorphism
    CFTR gene
    antioxidant enzyme activity
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 2; 221-225
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polymorphic analysis of peptide binding domain of major histocompatibility complex class I in domestic ducks
    Autorzy:
    Yu, S.
    Wu, J.
    Bai, J.
    Ding, Y.
    Qiu, W.
    Zhang, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087551.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    domestic duck
    highly variably sites
    MHC class I
    peptide binding domain
    phylogenetic tree
    polymorphism
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 2; 415-422
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characterisation of genome-wide structural aberrations in canine mammary tumours using single nucleotide polymorphism (SNP) genotyping assay
    Autorzy:
    Surdyka, M.
    Gurgul, A.
    Slaska, B.
    Pawlina, K.
    Szmatola, T.
    Bugno-Poniewierska, M.
    Smiech, A.
    Kasperek, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087566.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    dog
    cancer
    mammary tumour
    structural aberration
    CNV
    LOH
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 1; 133-141
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-12 z 12

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