Temat: sentinel lymph node - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Results of sentinel lymph node biopsy in patients with breast cancer in 10-year own material of the 4th Military Teaching Hospital with Polyclinic in Wrocław
Autorzy:: Kabziński, Piotr
Rac, Jacek
Dorobisz, Tadeusz
Pawłowski, Wiktor
Ziomek, Agnieszka
Chabowski, Mariusz
Janczak, Dawid
Leśniak, Michał
Janczak, Dariusz
Powiązania:: https://bibliotekanauki.pl/articles/1394134.pdf
Data publikacji:: 2016
Wydawca:: Index Copernicus International
Tematy:: breast cancer
sentinel lymph node
radioisotope
lymphoscintigraphy
Opis:: At present, sentinel lymph node biopsy is a standard procedure to assess the advancement of breast cancer and cutaneous melanoma. The aim of the study was to assess the role of the sentinel lymph node biopsy in the treatment of patients with breast cancer in our own material. Material and methods. Analyzed was medical documentation of 258 patients with initially operable breast cancer, qualified for operation with sentinel lymph node biopsy in 2004-2014 in the Department of Surgery of the 4th Military Teaching Hospital. A few hours prior to the planned surgery, radioisotope (technitium-99 sulfur colloid) was applied in the area of tumor or under the areola. 1-2 hours after administering the tracer, the lymphoscintigraphy with the labelling of the sentinel lymph node on the skin was performed. Results. On the basis of the gathered material, obtained were the following parameters: sensitivity – 100%, and specificity – 94.6%. Four cases were false negative (5.5%). Conclusions. 1. Marking the sentinel lymph node in breast cancer, based on the single visualisation method with the use of radioisotope, is a useful and effective technique. 2. The factor influencing the results of the sentinel lymph node biopsy (true positive and negative results and false negative result) was the number of the excised lymph nodes except for the sentinel lymph node. 3. Patients with estrogen receptor expression had often metastases to sentinel lymph node (145 cases – 56%). 4. The false negative rate, i.e. 5.5% in our material, is within the limits of acceptability given in the literature. 5. The sentinel lymph node biopsy performed by the experienced surgical team is a reliable diagnostic tool with a low complication rate.
Źródło:: Polish Journal of Surgery; 2016, 88, 3; 130-135
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Analysis of disease free survival in cutaneous melanoma patients subject to sentinel lymph node biopsy
Autorzy:: Łobaziewicz, Wojciech
Szloch, Joanna
Wajda, Justyna
Legkiy, Oleksandr
Marczyk, Elżbieta
Wysocki, Wojciech
Powiązania:: https://bibliotekanauki.pl/articles/1391682.pdf
Data publikacji:: 2020
Wydawca:: Index Copernicus International
Tematy:: cutaneous melanoma
disease free survival
lymphadenectomy
sentinel lymph node biopsy
SNB
Opis:: Introduction: Cutaneous melanoma is estimated for 2% of malignant neoplasms occurring in humans. It is characterized by a high level of malignancy and low sensitivity to cytostatic drugs. The incidence of cutaneous melanoma is increasing in Poland. The lymphatic system is the most common route of dissemination of this neoplasm. The appearance of a sentinel node biopsy technique has made it possible to identify patients with a regionally advanced disease. It is a minimally invasive method with a small percentage of complications. Aim: Analysis of disease free survival (DFS) in cutaneous melanoma patients with sentinel lymph node biopsy. Material and methods: The analysis included 222 patients with cutaneous melanoma treated in the Department of Oncological Surgery in 2010–2015, who underwent a sentinel node biopsy. The study group consisted of 136 women and 86 men, the average age of patients was 59 years. Patients were qualified for sentinel node biopsy based on clinical evaluation and ultrasound of regional lymph nodes. The average follow-up was 25.1 months. About 2 hours before surgery, patients received a radioisotope, then lymphoscintigraphy SPECT was performed. Additionally, they were administered the Patent Blue dye in the operating room. Results: The sentinel node was identified in 217 patients (98%), and the average sentinel nodes were 2.25. Twenty-seven patients (12%) had a metastasis in sentinel nodes. In this group, the duration of symptom free survival was significantly shorter. Sentinel node status and age of the patient were independent factors affecting the prognosis of disease free survival. Conclusions: Sentinel node biopsy is a precise method to identify patients with cutaneous melanoma who have metastasis to regional lymph nodes, as well as the most important prognostic factor.
Źródło:: Polish Journal of Surgery; 2020, 92, 3; 15-21
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Problems concerning patients’ qualification for surgical procedures allowing for evaluation of the condition of axillary fossa lymph nodes in the radical treatment of breast cancer
Autorzy:: Nowikiewicz, Tomasz
Śrutek, Ewa
Zegarski, Wojciech
Powiązania:: https://bibliotekanauki.pl/articles/1395654.pdf
Data publikacji:: 2015-06-01
Wydawca:: Index Copernicus International
Tematy:: breast cancer
conserving treatment
axillary lymphadenectomy
sentinel lymph node biopsy
surgical treatment
Opis:: The presence of metastases in the lymph nodes of the axillary fossa is the most important prognostic factor in patients with breast cancer. The surgical treatment option required for evaluation of the condition of the axillary lymph nodes depends on the results of a preoperative physical examination of the patients. The aim of the study was to evaluate the correctness of breast cancer patients’ qualification to surgical procedures allowing for evaluation of the condition of the axillary lymph nodes. Material and methods. A retrospective analysis of a group of 963 patients with a diagnosed malignancy of the breast, treated surgically in the period from 01 Jan 2011 to 29 Feb 2012. Depending on the result of evaluation of the axillary lymph node clinical condition, the patients underwent sentinel lymph node biopsy or elective axillary lymphadenectomy. Results. In 27.4% of patients subjected to excision of the sentinel lymph node, metastatic lesions were found in the lymph nodes removed during the procedure. In most cases (98.1%) that concerned the lymph nodes of the lower part of the axilla. In 17.4% of patients, metastases were located also in the middle or upper part (9%). In the group of patients primarily qualified to lymphadenectomy, the metastatic lesions in the axillary lymph nodes were diagnosed in 67.2% of patients. They were most commonly located in the lower part of the axillary fossa (in 96.7% of cases), and in 68.8% of patients in the middle or upper part (35.8%). Conclusions. Biopsy of the sentinel lymph node in patients with clinically advanced breast cancer is an effective and safe method of evaluation of the condition of the axillary fossa lymph nodes. A high rate of false positive results concerning the clinical stage of the disease requires changing the rules of patients’ qualification to elective axillary lymphadenectomy.
Źródło:: Polish Journal of Surgery; 2015, 87, 6; 290-294
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Clinical Significance of Van Nuys Prognostic Index As A Qualification Criterion to Sentinel Lymph Node Biopsy in Patients Diagnosed with Ductal Carcinoma in Situ
Autorzy:: Nowikiewicz, Tomasz
Wiśniewska, Magdalena
Wiśniewski, Michał
Zegarski, Wojciech
Powiązania:: https://bibliotekanauki.pl/articles/1395856.pdf
Data publikacji:: 2015-02-03
Wydawca:: Index Copernicus International
Tematy:: breast cancer
ductal carcinoma in situ
sentinel lymph node biosy
Van Nuys Prognostic Index
surgical treatment
Opis:: Diagnose of ductal carcinoma in situ (DCIS) requires, at least in a part of cases, assessment of auxiliary lymph nodes. The aim of the study was to analyze clinical value of Van Nuys Prognostic Index (VNPI) as the important criterion for qualification of DCIS patients to sentinel lymph node biopsy (SLNB). Material and methods. Analysis included patients diagnosed with DCIS and qualified to SLNB, operated in years 2004-2013. We performed a statistical analysis to assess correlation between VNPI value and positive pathological verification of excised sentinel lymph node (SLN). The influence of other clinical factors on presence of metastases in SLN was also determined. Results. 3,6% of DCIS patients were diagnosed with metastases in SLN. Metastases were diagnosed in 6.7% patients with VNPI > 10 points vs 3.4% in patients with VNPI < 10 points. In 75% of patients with metastatic SLN the value of VNPI was at least 10 points. In premenopausal patients metastases in SLN were diagnosed in 8.1% of cases vs 1.4% in postmenopausal patients. In patients diagnosed with cancer of the other breast metastases in SLN were found in 6.3% of cases vs 3.2% in one-sided cancer. Patients with multifocal cancer were over twice as often diagnosed with metastases in SLN (5% vs 2%). There was no correlation found between VNPI value and positive pathological verification of SLN. No differences between prevalence of SLN metastases depending on selected clinical features were found. Conclusions. Recommendation of VNPI as the criterion of qualification to SLNB starting with 10 points could be more favourable in patients with DCIS. Deciding on SLNB in DCIS patients, we should also take into consideration other clinical features.
Źródło:: Polish Journal of Surgery; 2014, 86, 10; 479-485
0032-373X
2299-2847
Pojawia się w:: Polish Journal of Surgery
Dostawca treści:: Biblioteka Nauki

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