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Wyświetlanie 1-5 z 5
Tytuł:
Morbidity, Mortality and Survival after Stomach Resection with or without Splenectomy – The Single Centre Observations
Autorzy:
Stojcev, Zoran
Bobowicz, Maciej
Jarząb, Michał
Pawłowska-Stojcev, Tomasz
Banasiewicz, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1396190.pdf
Data publikacji:
2013-08-01
Wydawca:
Index Copernicus International
Tematy:
neoplasm
stomach
splenectomy
complications
lymph node excision
Opis:
Over the last decade, gastric cancer treatment has changed from extensive multiorgan resections towards less invasive approaches with limited resections and a more selective lymphadenectomy. Despite all available trials, the conclusions on the extent of necessary resections still remain debatable. The aim of the study was to assess the short term outcomes (morbidity and mortality) of a total gastrectomy depending on the simultaneous splenectomy status. Material and methods. We performed a retrospective analysis of the records of all patients treated with a curative intent using a total gastrectomy for gastric cancer between 1997 and 2003. 49 patients fulfilled the inclusion criteria. Patients were divided into two groups: S(+) gastrectomy with splenectomy group (29 patients) and S(-) total gastrectomy with spleen preservation (20 patients). Results. Survival analysis at one year showed that there was no difference in survival between the two groups (p=0.84). There were six recurrences, one in the group S(+) and five in group S(-) (p>0.05). Dissemination was observed in three patients in group S(-) (p>0.05). Other complications including infectious complications, exenteration, subileus, cardiovascular insufficiency, multiorgan failure were more frequent in the S(+) group (31% v 15%) although the difference was not significant (p=0.17). Conclusions. Splenectomy during gastrectomy for cancer has no statistically significant impact on short-term morbidity and mortality. Even though it does not show benefit in terms of 5-year overall survival rates it might be performed when needed in more advanced cases in properly selected patients (e.g. upper gastric T3/4 gastric cancer)
Źródło:
Polish Journal of Surgery; 2013, 85, 8; 433-437
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vascular Endothelial Growth Factor and Survivin Immunostaining in Gastric Adenocarcinoma
Autorzy:
Bury, Jarosław
Szumiło, Justyna
Dąbrowski, Andrzej
Ciechański, Aleksander
Śliwińska, Justyna
Wallner, Grzegorz
Powiązania:
https://bibliotekanauki.pl/articles/1396680.pdf
Data publikacji:
2012-07-01
Wydawca:
Index Copernicus International
Tematy:
vascular endothelial growth factor
VEGF
survivin
adenocarcinoma
stomach
survival
Opis:
Two molecules - vascular endothelial growth factor involved in new vessels formation and survivin - antiapoptotic protein, reported to be associated with worse prognosis in various malignancies have been chosen for the study. Both are potential target for novel therapiesThe aim of the study was to determine the immunostaining of VEGF and survivin in gastric carcinoma and to analyse their relationship to the selected clinicopathological features and survival.Material and methods. Formalin-fixed, paraffin-embedded sections from 41 gastric adenocarcinomas were used for immunohistochemical reaction with monoclonal antibodies against vascular endothelial growth factor and survivin. The results were compared with selected clinicopathological features and survival.Results. Positive immunohistochemical reaction for vascular endothelial growth factor and survivin was revealed in 24 (58,53%) and 30 (73,17%), gastric carcinomas respectively. Vascular endothelial growth factor-negative gastric carcinomas were significantly more common in cases without metastases to regional lymph nodes and distant organs and in less advanced cases. Similar, distant metastases were also statistically less common in survivin-negative carcinomas. The differences in immunohistochemical reactions for survivin between less and more advanced cases almost reach statistical significance. The only factors significantly influenced 1, 2 and 3-year survival were vascular endothelial growth factor and survivin status. Statistically significant higher percentage of survival was noted in patients with vascular endothelial growth factor- and survivin-negative tumors.Conclusions. It seems that vascular endothelial growth factor and survivin play role in local invasion and spread of gastric adenocarcinoma and negatively influences survival. However, further studies are required to assess their true usefulness in the clinical practice.
Źródło:
Polish Journal of Surgery; 2012, 84, 7; 341-347
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ectopic Pancreas Imitating Gastrointestinal Stromal Tumor (GIST) In The Stomach
Autorzy:
Zińczuk, Justyna
Bandurski, Roman
Pryczynicz, Anna
Konarzewska-Duchnowska, Emilia
Kemona, Andrzej
Kędra, Bogusław
Powiązania:
https://bibliotekanauki.pl/articles/1395634.pdf
Data publikacji:
2015-05-01
Wydawca:
Index Copernicus International
Tematy:
ectopic pancreas
heterotopic pancreas
gastrointestinal stromal tumor
stomach
Opis:
Ectopic pancreas is a rare congenital disorder defined as pancreatic tissue lacking vascular or anatomic communication with the normal body of the pancreas. Most cases of ectopic pancreas are asymptomatic, but it may become clinically evident depending on the size, location and the pathological changes similar to those observed in case of the normal pancreas. It is often an incidental finding and can be located at different sites in the gastrointestinal tract. The most common locations are: the stomach, duodenum or the proximal part of small intestine. The risk of malignancy, bleeding and occlusion are the most serious complications. Despite the development in diagnostics, it still remains a challenge for the clinician to differentiate it from neoplasm. In this report, we described a case of 28-years old woman who presented recurrent epigastric pain. The upper gastrointestinal endoscopy revealed gastrointestinal stromal tumor on the border of the body and antrum of the back wall of great curvature of the stomach. The histopathological examination after surgery showed heterotopic pancreatic tissue. Ectopic pancreas should be considered in the differential diagnosis of gastric mass lesions.
Źródło:
Polish Journal of Surgery; 2015, 87, 5; 268-271
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of changes in body composition measured with bioelectrical impedance in patients operated for pancreatic, gastric and colorectal cancer
Autorzy:
Dzierżek, Przemysław
Kurnol, Krzysztof
Hap, Wojciech
Frejlich, Ewelina
Diakun, Agata
Karwowski, Adrian
Kotulski, Krzysztof
Rudno-Rudzińska, Julia
Kielan, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1391802.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
body composition
cioelectrical impedance
colorectal cancer
pancreatic cancer
stomach cancer
Opis:
ntroduction: A proper level of nutrition is significant in the period of convalescence in patients subject to major surgical procedures, particularly due to neoplastic disease. Bioelectrical Impedance Analysis, or BIA is a widely used method in assessing body mass composition. BIA measurement is easy, quick, cheap and repetitive. Material and methods: We assessed the body composition of 56 patients (25 women and 31 men) hospitalized and operated at the Department of General and Oncological Surgery of the Wroclaw Medical University in the years 2017–2018 using bioelectric impedance. Results: The average body weight loss in the 4th postoperative day was 1.32% of body mass and on the day of release from hospital – 4.23% of body mass in relation to body mass upon admission. The percentage of body fat (FM – Fat Mass) in patients admitted to the department is above the normal range. The change in body composition in hospitalized patients mainly concerns the amount of adipose tissue and the amount of extracellular and intracellular water (ECW – Extracellular Water; ICW – Intracellular Water). Conclusions: Bioelectrical impedance can be an easy and effective method of assessing body composition and its change in patients undergoing major surgery. Amongst the analyzed groups, patients operated for pancreatic cancer lose the largest percentage of body weight until discharge from the department. Loss of body mass mainly occurs as loss of fat mass (FM).
Źródło:
Polish Journal of Surgery; 2020, 92, 2; 8-11
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
IgG4-related disease manifesting as an isolated gastric lesion- a literature review
Autorzy:
Skorus, Urszula
Kenig, Jakub
Mastalerz, Kinga
Powiązania:
https://bibliotekanauki.pl/articles/1392432.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Autoimmune diseases
IgG4 related disease
Immunoglobulin G4
Inflammatory pseudotumor
Stomach
Opis:
Introduction: IgG4-related disease (IgG4-RD) is a newly recognised disorder of unknown etiology and pathogenesis, characterised by dense IgG4+ cells infiltration and fibrosis. IgG4-RD can affect various organs, but gastrointestinal tract involvement is rare. First case of isolated gastric IgG4-RD reported in polish population was diagnosed in our Clinic and became the reason for conducting a literature review. Materials and methods: A literature review was performed using PubMed database. Eight studies of isolated gastric IgG4-RD, published between 2011 and 2017, and a case diagnosed by the authors were included. Results: Three out of nine analysed patients had gastrointestinal complaints. In other cases lesions were detected accidentally. The majority of them were submucosal tumors while only one was a gastric ulcer. The most commonly affected was the stomach body. In all cases malignancy had been suspected, and the lesions were surgically removed. Diagnosis was based on the histopathology image and immunohistochemical staining. Only one patient had elevated IgG4 serum level. No case of recurrence or other organ involvement was reported. Conclusion: IgG4-related disease may manifest as an isolated gastric lesion and should be taken in consideration in differential diagnosis. Making an ultimate diagnosis without histopathological specimen examination seems to be difficult and can lead to misdiagnosis followed by inappropriate treatment. IgG4-RD responds well to steroid therapy. However, on this matter further studies are needed.
Źródło:
Polish Journal of Surgery; 2018, 90, 4; 41-45
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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