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Wyszukujesz frazę "Janusz, Marcin" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Anticoagulants as a Risk Factor in Patients Operated on for Abdominal Hernia
Autorzy:
Piątek, Barbara
Piwnik, Marcin
Podgórski, Michał
Strzelczyk, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1395815.pdf
Data publikacji:
2014-06-01
Wydawca:
Index Copernicus International
Tematy:
abdominal hernia
anticoagulants
acetylsalicylic acid
low-molecular-weight heparin
vitamin K antagonists
haemorrhagic complications
Opis:
The aim of the study was to determine whether patients treated with anticoagulants in the perioperative period are at higher risk of developing bleeding complications. Material and methods. Medical records of patients operated for abdominal hernia were analysed. Data concerning demographic characteristic of a group, type of hernia, comorbidities, preoperative anticoagulation therapy and complications were collected. Association of applied anticoagulation therapy with the time of drainage, the amount of drained discharge and the length of hospitalisation was evaluated. Results. Analysed group consisted of 186 patients. Thirty seven patients were treated with different schemes of anticoagulant therapy before the the surgery. Patients treated with triple anticoagulation therapy (acetylsalicylic acid, low-molecular weight heparin, vitamin K antagonists) had significantly longer time of drainage in comparison to patients treated according to other schemes (p<0.05). The amount of drained discharge and time of hospitalisation did not differ significantly. Neither comorbidities nor the administration of low-molecular weight heparin did not affect the analysed parameters. Conclusions. Patients operated on abdominal hernia, who were treated with triple anticoagulation therapy in peri-operative period, require significantly longer drainage of the wound what can result in prolonged hospitalisation
Źródło:
Polish Journal of Surgery; 2014, 86, 6; 263-267
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CIDE-A gene expression in patients with abdominal obesity and LDL hyperlipoproteinemia qualified for surgical revascularization in chronic limb ischemia
Autorzy:
Feldo, Marcin
Kocki, Janusz
Łukasik, Sylwia
Bogucki, Jacek
Feldo, Jan
Terlecki, Piotr
Kęsik, Jan
Wroński, Jacek
Zubilewicz, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1396483.pdf
Data publikacji:
2013-11-01
Wydawca:
Index Copernicus International
Tematy:
CIDE-A gene
obesity
femoro-popliteal revascularisation
dyslipidemia
Opis:
According to the latest data, CIDE -A gene plays a key role in the regulation of body weight in both humans and mice, and therefore it is regarded a potential candidate gene for human obesity. The aim of the study was to define the role of CIDEA gene in patients with dyslipidemia and symptomatic limb ischemia. Material and methods. The study group contained 28 patients, including 17 men and 11 women. Patients were enrolled in the study group, depending on the value of body mass index (BMI); there was BMI>30 for obese patients. The group included untreated patients (n=14) and patients (n=14) receiving atorvastatin 20 mg/day for at least three months prior to the initiation of the study. The control group (n=16) contained patients with no lipid disorders. A one-step isolation of RNA from lymphocytes and adipose tissue cells was carried out using the TRI method modified by Chomczyński and Sacchi. Next, gene expression was tested using real-time PCR. Results. The highest mean relative expression of CIDE -A gene occurred in patients with normal body weight. The lowest mean relative expression of CIDE-A gene was observed in obese patients with lipid disorders. A high negative correlation (r=-0.7919) of CIDE -A gene expression, depending on BMI, was reported in the group of obese patients with lipid disorders. Conclusions. Due to an important role of Cide-A protein demonstrated in the development of metabolic diseases such as obesity, metabolic syndrome, type 2 diabetes and their vascular complications, CIDE -A gene and protein are potential therapeutic targets in the case of these diseases.
Źródło:
Polish Journal of Surgery; 2013, 85, 11; 644-648
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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