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Tytuł:
Effect of complicated thyroid surgical procedures on personal and professional life of patients
Autorzy:
Sławeta, Norbert
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1396740.pdf
Data publikacji:
2012-10-01
Wydawca:
Index Copernicus International
Tematy:
thyroid surgical
vocal cord paralysis
post-operative hypoparathyroidism
Opis:
Thyroid resection procedures are the most common endocrine surgery procedures in Poland; an estimated 25 000 procedures are performed annually. Long term patient outcomes are rarely analyzed. The aim of the study was to assess effect of complicated thyroid burgery procedur es on personal and Professional life of patients. Material and methods. Follow-up of patients with complications was conducted according to a predetermined protocol involving survey and biochemistry. Results. Unilateral and bilateral vocal cord paralysis accounted for 69% and 8% of complications, respectively. The complications resolved unilaterally in 58% of patients with bilateral vocal cord paralysis. Persistent hypoparathyroidism accounted for 26% of cases of postoperative hypoparathyroidism. Following thyroid resection procedures all patients received supplementation of thyroid hormones and were monitored by an endocrinologist until their follow-up examination. Eighty eight percent patients with vocal cord paralysis were treated at an outpatient department of laryngology and/or speech therapy. Physical therapy resulted in improvement irrespective of final nature of the complications. Vocal cord paralysis or both complications concurrently result in marked prolongation of absence from work and resulted in disability pension in 15% of professionally active patients. Low level of adaptation to diseas e was found in 19% patients in the study group, while low score on Satisfaction with Life Scale (SWLS) was found in 17% patients in the study group, irrespective of the type of complication. Conclusions.Acceptance of complications after thyroid surgical procedures is difficult for patients and worsens their life satisfaction in the long term follow-up and adversely modifies their professional and personal life. In the long term perspective, persistent hypoparathyroidism is more burdensome for patients than recurrent laryngeal nerve injury. Chronic deficit of innervations does not require chronic substitution or specialist therapy that are necessary in the persistent hypoparathyroidism.
Źródło:
Polish Journal of Surgery; 2012, 84, 9; 437-444
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Free gas in the peritoneal cavity after colonoscopy. Indication for immediate action or incidental finding in imaging tests after uncomplicated colonoscopy? Literature review
Autorzy:
Znamirowski, Przemysław
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1391696.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
asymptomatic pneumoperitoneum
colonoscopy
complications
dissection
mucosectomy
perforation
Opis:
Colonoscopy is a routine diagnostic and therapeutic procedure. Along with the increase in the complexity of the procedures performed, the risk of complications increases. In 2017, WSES (World Society of Emergency Surgery) published the principles of safe colonoscopy. Intestinal perforation is one of the most common complications. The risk of perforation in treatment procedures such as mucosectomy or endoscopic dissection is significantly greater than the risk of diagnostic colonoscopy. The basic rule of the procedure in case of suspected perforation is close supervision over the patient’s condition and the soonest possible repair of damage. The role of the endoscopist is not only early recognition, but also early treatment of damage. Immediate endoscopic treatment of lesions is an effective, final and acceptable management strategy. In patients who have undergone imaging diagnostics for another reason, free gas in the peritoneal cavity can be recognized. It does not have to mean the need for urgent surgical intervention. Patients with asymptomatic pneumoperitoneum after colonoscopy should, however, be treated as patients with suspected perforation of the large intestine and undergo careful clinical observation in accordance with WSES recommendations. Colonoscopy is a procedure with a risk of complications, which should be reported to patients qualified for endoscopy, but appropriate management reduces the risk of morbidity and mortality associated with this procedure.
Źródło:
Polish Journal of Surgery; 2020, 92, 3; 44-50
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wolny gaz w jamie otrzewnej po kolonoskopii. Wskazanie do natychmiastowego działania czy przypadkowe znalezisko w badaniach obrazowych po niepowikłanej kolonoskopii? Przegląd piśmiennictwa
Autorzy:
Znamirowski, Przemysław
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1391702.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
bezobjawowa odma otrzewnowa
dysekcja
kolonoskopia
mukozektomia
powikłania
przedziurawienie
Opis:
Kolonoskopia jest rutynową procedurą diagnostyczną i terapeutyczną. Wraz ze wzrostem złożoności wykonywanych procedur zabiegowych, rośnie ryzyko wystąpienia powikłań. WSES (World Society of Emergency Surgery) w 2017 roku opublikowało zasady bezpiecznego wykonywania kolonoskopii. Do najczęstszych powikłań należy przedziurawienie przewodu pokarmowego. Ryzyko przedziurawienia w przypadku zabiegów leczniczych, takich jak mukozektomia czy dysekcja endoskopowa, jest znacząco większe od ryzyka kolonoskopii diagnostycznej. Podstawową zasadą postepowania w sytuacji podejrzenia przedziurawienia jest ścisły nadzór nad stanem chorego oraz możliwe szybkie zaopatrzenie uszkodzenia. Rola endoskopisty nie sprowadza się tylko do rozpoznania, ale także do wczesnego zapatrzenia uszkodzenia. Natychmiastowe leczenie endoskopowe uszkodzeń jest skuteczną, ostateczną i akceptowalną strategią postepowania. U pacjentów po kolonoskopii, których poddano diagnostyce obrazowej z innego powodu, można rozpoznać wolny gaz w jamie otrzewnej. Nie musi to jednak oznaczać konieczności pilnej interwencji chirurgicznej. Chorych z bezobjawową odmą otrzewnową po kolonoskopii należy traktować jak pacjentów z podejrzeniem przedziurawienia jelita grubego i poddawać starannej obserwacji klinicznej, zgodnie z zaleceniami WSES. Kolonoskopia jest zabiegiem obarczonym ryzykiem powikłań, o czym należy informować chorych kwalifikowanych do endoskopii, jednak właściwe postępowanie zmniejsza ryzyko zachorowalności i śmiertelności związanych z tą procedurą.
Źródło:
Polish Journal of Surgery; 2020, 92, 3; 44-50
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence and Progression of Acute Pancreatitis in the Świętokrzyskie Voivodeship Population
Autorzy:
Głuszek, Stanisław
Kozieł, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1397025.pdf
Data publikacji:
2012-12-01
Wydawca:
Index Copernicus International
Opis:
Acute pancreatitis (AP) is a significant clinical problem. There have been no prospective epidemiological data on AP in Poland. The aim of this study is to estimate prevalence, etiology and severity of acute pancreatitis in the Świętokrzyskie Voivodeship population, involving risk factors of this disease. Material and methods. In 2011 prospective observation was conducted in all departments of surgery of the Świętokrzyskie Voivodeship. The inclusion criterion of the study, a definite diagnosis of AP, was met in 1044 hospitalized patients. According to our assumption that repeated hospitalization is considered as a new case if occurred more than 60 days after the previous one, 1004 patients were included in the further analysis. Results. The incidence rate was 99.96/100,000. Incidence rate among woman was 72/100,000 and incidence among men was 130.24/100,000 (p < 0.05). Median age of AP patients was 53 years. Median age among woman (65 years) was significantly (p < 0.005) higher than among man (47 years). Incidence rate for the first episode was 79.7/100,000 citizens. Main causes of AP included cholelithiasis (30.1%), alcohol (24.1%), coexisting cholelithiasis and alcohol abuse (2.9%), pancreatic cancer (1%), AP after ERCP (0.7%). Basing on modified Atlanta criteria, severe AP was diagnosed in 7%, moderate in 12.3%, and mild in 80.7% of patients. Mean duration of hospitalization of patients with severe AP was 14.8, moderate - 16,7, mild - 7.1 days. Mortality rate for AP was 3.9%. Mean age of deceased women was 74 years and was significantly higher than in the group of men (61 years). Mortality rate in severe AP was 52.9% and was significantly (p < 0.05) higher than mortality in moderate (no deaths) or mild AP (0.2%). Conclusions. Incidence rate of AP in the Świętokrzyskie Voivodeship population is among the highest in Poland. Our study indicates that new Atlanta classification, that differentiates between moderate and severe AP, needs to be implemented to the clinical practice, since the latter carries high mortality in severe cases.
Źródło:
Polish Journal of Surgery; 2012, 84, 12; 618-625
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical and Metabolic Changes Following Complicated Thyroid Resection Procedures
Autorzy:
Sławeta, Norbert
Głuszek, Stanisław
Heciak, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1396347.pdf
Data publikacji:
2013-05-01
Wydawca:
Index Copernicus International
Tematy:
thyroid surgery
thyroid surgery complications
hypoparathyroidism
vocal cord paralysis
Opis:
Clinical and metabolic consequences of complicated thyroid resection procedures are rarely an object of complex analysis, and teams participating in treatment may have a very limited knowledge of them. The aim of the study was to assess clinical and metabolic consequences of complicated thyroid surgical procedures. Material and methods. In the years 2002-2007, 756 patients underwent surgery due to non-neoplastic thyroid diseases. Sixty-nine (9.1%) patients experienced complications manifesting as vocal cord paralysis and/or hypoparathyroidism. Follow-up examination was conducted in a group of 42 persons, which amounted to 61% of patients who experienced complications following thyroid surgical procedures. Follow-up examination, comprising assessment of morphotic blood elements, electrolyte, lipid and parathormone blood concentrations, thyroid hormone activity, respiratory function, vocal cord mobility, bone mineralization and ultrasound examination of the pocket left after thyroid resection, was conducted after the mean period of 43 months following surgery. Results. In the analyzed group, no significant differences in plasma electrolyte content were found (sodium, potassium, magnesium, calcium and phosphorus ions). In the group of patients with chronic hypoparathyroidism, no hypophosphatemia was observed, and there were no reports of concomitant nephrolithiasis or cataract. Increased cholesterol concentration was observed in the group of patients with chronic hypoparathyroidism and without hypoparathyroidism (p = 0.07). In 35% of patients with chronic vocal cord paralysis, abnormal results of spirometry tests were obtained. In the group of patients with chronic hypoparathyroidism, densitometry examination revealed higher T-score values compared with patients with transient hypoparathyroidism and vocal cord paralysis (p = 0.07). No bone mineralization disorders manifesting as pathological fractures were noted. Conclusions. The knowledge of clinical and metabolic consequences of complicated thyroid surgical procedures, due to their complexity, may be very limited among the members of both surgical teams and teams involved in management of complications. Development of a complication following thyroid surgery may be associated with significant homeostasis disorders, especially as regards calcium-phosphate metabolism, the skeletal system and the respiratory system. Such disorders can manifest long after the disease onset, only properly intensified and long-term management allows limitation of their extent.
Źródło:
Polish Journal of Surgery; 2013, 85, 5; 235-246
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Influence of Splenectomy Performed Simultaneously with Gastrectomy on Postoperative Complications in Patients with Gastric Cancer Undergoing Surgery with the Intention to Treat
Autorzy:
Głuszek, Stanisław
Kot, Marta
Kuchinka, Jakub
Matykiewicz, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1395800.pdf
Data publikacji:
2014-07-01
Wydawca:
Index Copernicus International
Tematy:
splenectomy
gastrectomy
surgical complications
general complications
gastric cancer
Opis:
Despite the growing understanding of the pathophysiological processes in the perioperative period and significant advancements in surgical techniques, operative treatment for gastric cancer remains a challenge for surgeons, especially because the primary procedure of total or nearly total gastrectomy must at times be extended by the resection of other organs. The aim of the study was to asses the influence of concomitant splenectomy in patients undergoing curative surgery for gastric cancer on postoperative complications. Material and methods. The study population consisted of 258 patients who underwent surgical treatment for gastric cancer with the intention to treat. The study assessed the influence of extending the surgical intervention by splenectomy on postoperative complications, both general and surgical, including the most severe of these, i.e. oesophago-gastric anastomotic leakage, duodenal stump leakage and peritoneal fluid infections. Results. Among the 258 gastric cancer patients receiving curative surgical treatment, the most common simultaneous intervention was splenectomy: 42/258 (16.3%), which was also accompanied by partial pancreatectomy in 8 cases. The number of surgical postoperative complications, major and minor, was similar in both subgroups: with and without splenectomy. Minor general complications, such as pyrexia with no clinically apparent reason, atelectasis, pneumonia and pleural effusion were statistically significantly more common in the subgroup with splenectomy (p=0.0001). Conclusion. Splenectomy performed concomitantly with gastrectomy for gastric cancer increases the risk of minor general complications. However, it does not increase the risk of severe surgical complications, such as oesophago-intestinal anastomotic leakage and does not increase the risk of death
Źródło:
Polish Journal of Surgery; 2014, 86, 7; 312-318
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Risk of Surgical Treatment in Patients Aged 85+, with Special Consideration of Colorectal Cancer
Autorzy:
Stępień, Renata
Głuszek, Stanisław
Kozieł, Dorota
Kaczmarczyk, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1395734.pdf
Data publikacji:
2014-03-01
Wydawca:
Index Copernicus International
Tematy:
operative risk
age 85+
colorectal cancer
Opis:
The increase in prevalence of chronic diseases in old age is concomitant with increasing risk of neoplasms requiring surgical treatment. The aim of the study was to assess the indications, treatment outcomes, complications and mortality associated with surgical treatment of patients aged 85 or more, with special consideration of colorectal cancer. Material and methods. The retrospective analysis involved a group of 94 patents (x = 88.9) aged 85 or more and treated surgically in the years 2006-2011. The results were compared with a randomly selected control group of 91 patients aged 45-75 (x = 56,4) and treated surgically in the same period. Results. Neoplastic diseases in the study group (85 ≥), compared with the control group (< 75), were a significantly more frequent indication for surgical treatment (p < 0.01). In the group of patients aged 85 or more, the most frequent indications for elective surgery were neoplasms of the skin and subcutaneous tissue (26.4%) and gastrointestinal neoplasms, mainly colorectal cancer (23.5%). Postoperative complications were significantly more frequent (p < 0.01) among patients aged 85 or more (n = 27; 34.8%) than in the younger group (n = 17; 18.7%). Postoperative mortality among patients undergoing emergency surgery was significantly higher (p < 0.05) in the senior group than in the group of younger patients. Conclusions. Surgical procedures in patients aged 85 or more are most frequently performed in the emergency setting, and their most common cause are neoplastic diseases. Emergency surgical treatment in patients aged 85 or more is associated with a significantly higher risk, compared with younger age groups, of developing multi-organ postoperative complications, usually leading to death. Elective surgical treatment in patients aged 85+ after appropriate preoperative preparation and in the group of younger patients shows similar early outcomes.
Źródło:
Polish Journal of Surgery; 2014, 86, 3; 132-140
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Severe vascular complications of acute pancreatiti
Autorzy:
Głuszek, Stanisław
Nawacki, Łukasz
Matykiewicz, Jarosław
Kot, Marta
Kuchinka, Jakub
Powiązania:
https://bibliotekanauki.pl/articles/1394278.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
Acute pancreatitis
complications
bleeding into the pancreatic tumour
Opis:
Acute pancreatitis (AP) develops as a result of the imbalance of the mechanisms inhibiting the activity of enzymes in the pancreatic cells, which causes their autoactivation in the pancreas. The incidence of AP ranges from 10 up to 100 cases per 100,000 population per year in different parts of the world. The overall mortality rate for acute pancreatitis is 10- 15%. The mortality rate in patients diagnosed with the severe form of acute pancreatitis is up to 30- 40%. Material and methods. The study included 10 patients treated due to acute pancreatitis in two surgical departments run by one of the authors (S.G.) in the years 2004-2014, who developed a serious complication in the form of haemorrhage into the inflammatory tumour/pancreatic cyst or an adjacent organ. Haemorrhage was diagnosed based on the clinical picture, most often a sudden drop in blood pressure, peritonitis symptoms and imaging findings – abdominal ultrasound and abdominal computed tomography. Therapeutic methods included conservative treatment, endovascular embolisation and, in the absence of efficacy of the above mentioned methods, surgical treatment. Patients age and gender, the etiological factor, comorbidities, Atlanta Classification, treatment outcomes and mortality rate were assessed. Results. Alcohol was the most common etiological factor in the investigated AP cases. The patients received conservative treatment, interventional radiology treatment (endovascular embolisation) or surgical treatment. In the study group, 6 patients required surgical treatment, 3 patients received invasive radiology treatment, and conservative treatment was used in one patient. The mortality rate in the study group was 30%. Conclusions. Haemorrhages into the inflammatory cisterns or adjacent organs (stomach, transverse colon mesentery) secondary to AP are the most severe complications, which are difficult to manage. The successful use of interventional radiology methods to inhibit and prevent the recurrence of bleeding in some of the patients is a significant milestone.
Źródło:
Polish Journal of Surgery; 2015, 87, 10; 485-490
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fournier gangrene – a challenge for the surgeon
Autorzy:
Kuchinka, Jakub
Matykiewicz, Jarosław
Wawrzycka, Iwona
Kot, Marta
Karcz, Włodzimierz
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1391522.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
Fourniere gangrene
hyperbaric oxygen treatment
early surgical approach
Opis:
Introduction. Fournier gangrene (FG) is life - threatening condition, defined as the necrotizing fascitis of perineum and can spread to the adjacent areas. It is rare disease and infection is caused by mixed bacterial flora, seldom by fungal infection. Risk factors are: male sex, diabetes, hypertension, malignant neoplasms, alcoholism, immunospression. Material and methods. The analysis of four group patients treateted for Fournier gangrene was made about diagnostic and therapeutic process, assessment of prognosis based on Fournier’s Gangrene Severity Index). Results. All patients were males. Average age at the moment of diagnosis was 60 years. All of them had comorbidities resulting with the higher risk of susceptibility to FG. Morbitity was 50%, despite of all of patients had less than 9 points in FGSI. Discussion. The FG, despite of better diagnostic tools and technological progres remaines the significant clinical issue because of the mortality - 80%. „The golden standard” is surgical excision of necrotic tissues, antibiotics support, equation of fluid, electrolytes and base – acid balance, level of glycemia is very important. The treating results were assessed on the base of FGSI. The significance has the moment of performing the surgical intervention – it is proven, that should be carried out during 24 hours. The hyperbaric oxygen therapy is controversial. Seem to be appropriate if the infection is caused by anaerobic bacteria. Conclusions. Fournier syndrome is significant clinical issue. Its treatment requires early surgical approach with exicision of necrotic tissues, antibiotics support and treatment of hyperbaric oxygen in some cases.
Źródło:
Polish Journal of Surgery; 2021, 93, 1; 55-60
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Can urea breath test (UBT) replace rapid urea test (RUT)?
Autorzy:
Nawacki, Łukasz
Czyż, Agata
Bryk, Piotr
Kozieł, Dorota
Stępień, Renata
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1392890.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Helicobacter pylori
urea breath test
rapid urea test
gastric cancer
Opis:
Background: Helicobacter pylori (Hp) is classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen. Its influence on the carcinogenesis of gastric cancer has been confirmed in many research studies. The conclusion is obvious - early detection and eradication of Hp can prevent the development of the disease. Methods: The objective of the study was to analyze the clinical and practical value of Carbon-13 urea breath test (UBT) in patients hospitalized due to pain complaints in the upper abdomen and dyspeptic symptoms. Fifty patients were enrolled in the study. Each patient underwent urea breath test according to the instruction included by the producer. Thereafter, each patient included in the study group was subjected to endoscopy of the upper gastrointestinal tract with the biopsy of the mucosa to determine the urease activity with rapid urease test (RUT). Results: In the study group, 14 patients (28%) achieved a positive urease test result which was confirmed in RUT. Four (8%) patients, despite a positive breath test, did not have a positive result in urease activity test from gastric mucosa. In 2 cases (4%) despite negative result of UBT, urease activity was confirmed in gastroscopic sections. The remaining 30 patients (60%) had a negative result in both studies. Conclusions: The limited availability of the gold standard for diagnostics of upper gastrointestinal tract diseases (gastroscopy) is the basis for the search for new methods of detection of Helicobacter pylori infections. The urea breath test is a method of high sensitivity and specificity. The positive result of urea breath test may be the basis for inclusion of eradication therapy.
Źródło:
Polish Journal of Surgery; 2018, 90, 5; 44-48
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czy ureazowy test oddechowy (UBT) może zastąpić szybki test ureazowy (RUT)?
Autorzy:
Nawacki, Łukasz
Czyż, Agata
Bryk, Piotr
Kozieł, Dorota
Stępień, Renata
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1392903.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
Helicobacter pylori
ureazowy test oddechowy
szybki test ureazowy
rak żołądka
Opis:
Wstęp: Helicobacter pylori (Hp) jest zaliczany przez International Agency for Research on Cancer (IARC) do pierwszej grupy karcynogenów. Wpływ bakterii na rozwój raka żołądka został potwierdzony w wielu badaniach. Wniosek jest oczywisty:...
Źródło:
Polish Journal of Surgery; 2018, 90, 5; 44-48
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Risk factors of pancreatitis after endoscopic retrograde cholangiopancreatography – a retrospective cohort study
Autorzy:
Głuszek, Stanisław
Matykiewicz, Jarosław
Kozieł, Dorota
Klimer, Dariusz
Wawrzycka, Iwona
Ogonowska, Aleksandra
Powiązania:
https://bibliotekanauki.pl/articles/1394275.pdf
Data publikacji:
2015
Wydawca:
Index Copernicus International
Tematy:
endoscopic retrograde cholangiopancreatography
acute pancreatitis
complication
Opis:
Endoscopic retrograde cholangiopancreatography (ERCP) is the most important non-surgical procedure in serious pancreatic and biliary diseases, still burdened with the risk of severe complications. The objective of the study was to distinguish factors which could increase the risk of occurrence of ERCP complication in the form of pancreatitis. Material and methods. The study included 452 patients who had undergone ERCP. Patients’ records were retrospectively analyzed from the aspect of demographic data, indications for the procedure, type and course of the procedure, type and severity of complications, width of the common bile duct (CBD), concomitant diseases and administered medicines which might increase the risk of complications. Results. In 35 patients (7.7%) a complication occurred in the form of pancreatitis (AP). A severe course was confirmed in 11 patients (31%). Cholelithiasis constituted approximately 2/3 of indications for ERCP. AP after ERCP was significantly more often observed in the group of patients aged under 40 (22.9% vs 8.6%; p<0.05). Narrow biliary ducts (3-8 mm) were the factor increasing the frequency of development of AP (25.9% vs 45%; p<0.05). Death occurred in 5 patients (1.1%), including 4 patients (0.96%) in the group without complications, and in 1 patient (2.85%) with complicated AP. Conclusions. ERCP is a very valuable procedure in clinical treatment; however, it is burdened with the risk of complications, such as AP, bleeding, or duodenal perforation. A group especially exposed to the risk of complications in the form of AP are young patients aged under 40 with a narrow CBD.
Źródło:
Polish Journal of Surgery; 2015, 87, 10; 499-505
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Polimorfizm genu CTRC może być czynnikiem zwiększającym ryzyko raka trzustki – badanie wstępne
Autorzy:
Głuszek, Stanisław
Kowalik, Artur
Kozieł, Dorota
Wawrzycka, Iwona
Głuszek-Osuch, Martyna
Matykiewicz, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1393376.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
rak trzustki
polimorfizm CTRC
etiologia
Opis:
Rak trzustki jest chorobą o wysokiej śmiertelności z powodu późnego rozpoznania i trudności w leczeniu. Cel: Celem badania była analiza mutacji wybranych genów SPINK1, CTRC, CFTR i PRSS1 oraz ich porównanie w tkance nowotworowej i krwi obwodowej u pacjentów leczonych z powodu raka trzustki. Materiał i metody: Do badania zakwalifikowano 16 pacjentów z rozpoznaniem guza trzustki. Do badań genetycznych pobrano u nich próbki tkanki nowotworowej, zdrowej tkanki trzustkowej i krwi obwodowej. Grupa kontrolna składała się z 419 zdrowych osób. Próbki krwi obwodowej pobrano od wszystkich uczestników badania do probówek z EDTA. Wyniki: Spośród 16 pacjentów ze wstępnym rozpoznaniem guza trzustki, raka trzustki potwierdzono badaniem mikroskopowym u 12 pacjentów (średni wiek: 60,2 lat). U 5 pacjentów zaobserwowano polimorfizm CTRC Hetero p.G60 = (c.180C >T) (41,7% pacjentów vs 18,6% w grupie kontrolnej). W pozostałej grupie pacjentów z rakiem trzustki u jednego chorego stwierdzono dodatni wywiad rodzinny, mutację SPINK1 (p.N34S) obserwowano u 1 na 12 pacjentów (8,3%) vs 12 na 419 badanych (2,9%) w grupie kontrolnej, a mutację CTRC (p.R254W) u 1 na12 chorych (8,3%) vs 4 na 419 badanych (1%) we krwi zdrowej populacji. Wnioski: Wstępne badania wskazują na potrzebę dalszej weryfikacji otrzymanych wyników sugerujących częstsze występowanie polimorfizmu p.G60= (c.180C >T) genu CTRC u chorych na raka trzustki.
Źródło:
Polish Journal of Surgery; 2017, 89, 5; 48-53
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Tumors of the right atrium and the inferior vena cava operated in deep hypothermic circulatory arrest
Autorzy:
Pietrzyk, Edward
Jelonek, Olga
Gorczyca, Iwona
Bryk, Piotr
Wożakowska-Kapłon, Beata
Głuszek, Stanisław
Powiązania:
https://bibliotekanauki.pl/articles/1391729.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
tumor
right atrium
inferior vena cava
Opis:
Introduction: Tumors which most frequently metastasize to the heart include: malignant melanoma, lung cancer, breast cancer, ovarian cancer, kidney cancer, leukemia, lymphomas and esophageal cancer. Purpose: The purpose of this paper was clinical analysis of a group of patients operated in deep hypothermic circulatory arrest due to tumors of the right atrium and the inferior vena cava. Material and method: The study covered 7 patients operated at the Cardiac Surgery Clinic with a cardiac tumor diagnosed on the basis of an echocardiographic assessment in the years 2012–2019. Before qualifying for surgical treatment, each patient underwent: thorough interview and physical examination, 12-lead ECG, laboratory tests and echocardiography. Patients additionally underwent: computed tomography of the chest or abdomen, magnetic resonance imaging and coronary angiography on the basis of which patients with significant coronary artery changes underwent simultaneous coronary artery bypass graft. After preparation, the tumor was excised from the vena cava and right atrium with simultaneous removal of the primary tumor, most often kidney cancer. Early and distant results of treatment were analyzed in the examined group of patients to determine the following endpoints: hospital mortality and survival after surgery: after 3 months and 12 months. Results: Of all operated patients: 2 individuals died in the early postoperative period due to hemorrhagic complications (hospital mortality – 28.6%), and 5 patients (71.4%) were discharged from the Clinic in a good general condition. In total, 3-month survival was 71.4%, and 12-month survival amounted to 28.6%. Conclusions: Surgeries are very complex and challenging, and usually take on average 8–10 hours. It can improve the outcomes of palliative oncological treatment, better physical function (cardiovascular fitness) and extend life from several months to several years in more than ²/3 patients.
Źródło:
Polish Journal of Surgery; 2020, 92, 4; 17-22
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CTRC gene polymorphism may increase pancreatic cancer risk – preliminary study
Autorzy:
Głuszek, Stanisław
Kowalik, Artur
Kozieł, Dorota
Wawrzycka, Iwona
Głuszek-Osuch, Martyna
Matykiewicz, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/1393315.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
pancreatic cancer
CTRC polymorphism
etiology
Opis:
Pancreatic cancer is often fatal due to delayed diagnosis and treatment difficulties. Objective: To analyze selected SPINK1, CTRC, CFTR, and PRSS1 gene mutations in cancer tissue and blood samples of patients with pancreatic tumors. Materials and method: We enrolled 16 consecutive patients diagnosed with pancreatic tumors. We collected cancer tissue, normal pancreatic tissue, and blood samples for genetic tests. The control group consisted of 419 healthy individuals. Peripheral blood samples were collected from all study participants in EDTA-coated tubes. Results: Out of 16 patients with pancreatic tumors, 12 had pancreatic cancer on microscopic examination (mean age, 60.2 years). The CTRC polymorphism Hetero p.G60=(c.180C>T) was found in 5 patients with pancreatic cancer (41.7% vs. 18.6% in the control group). One patient with pancreatic cancer and a positive family history had the SPINK1 (p.N34S) mutation [8.3% vs. 2.9% (12/419) in the control group]. One patient with pancreatic cancer had the CTRC (p.R254W) mutation [8.3% vs. 1% (4/419) in the control group]. Conclusions: Our preliminary results show that the CTRC polymorphism p.G60= (c.180C>T) is frequent in patients with pancreatic cancer. However, further research is needed to verify our findings.
Źródło:
Polish Journal of Surgery; 2017, 89, 5; 48-53
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
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