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Wyświetlanie 1-15 z 139
Tytuł:
Knowledge and Awareness of Colorectal Cancer
Autorzy:
Lewandowski, Miłosz
Lipiński, Przemysław
Bednarski, Igor
Mik, Michał
Dziki, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1391790.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
awareness
colon cancer
colonoscopy
colorectal cancer
rectal cancer
stomy
Opis:
Introduction: Colorectal cancer (CRC) is the third most common malignancy in men and the second most common in women. The disease constitutes a significant civilization and social problem. The aim: The aim of the study is to assess the sudy group’s awareness and knowledge about CRC, as well as about its diagnostics and treatment. Material and methods: An online questionaire form was distributed in the study group regarding issues related to CRC, and followed by statistical analysis and interpretation of the obtained survey results. Results: After analysis, we found that a significant percentage of the surveyed sample group had basic knowledge and awareness in the area of CRC, whereas about half of the respondents did not consider themselves sufficiently informed about the disease. Conclusions: Considering the scale of the problem posed by CRC, it is necessary to undertake broader action to promote knowledge about this disease and to carry out this type of research on a larger and more socioeconomically diverse population.
Źródło:
Polish Journal of Surgery; 2020, 92, 2; 34-41
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Brain metastasis as the first symptom of gastric cancer – case report and literature review
Autorzy:
Murawa, Dawid
Nowaczyk, Piotr
Szymkowiak, Małgorzata
Karaszewska, Bogusława
Powiązania:
https://bibliotekanauki.pl/articles/1396242.pdf
Data publikacji:
2013-07-01
Wydawca:
Index Copernicus International
Tematy:
gastric cancer
gastric cancer symptoms
gastric cancer metastases
brain metastases
Opis:
The study presented a patient with asymptomatic gastric cancer, in whom the first symptom was metastasis to the brain. The patient was initially diagnosed by a neurologist and subject to surgical intervention in the area of residence, where he underwent craniotomy with the excision of the metastatic lesions located in the occipital lobe. The histopathological examination revealed the presence of adenocarcinoma metastases. Following complex diagnostics the patient was diagnosed with cardial carcinoma, being subject to cerebral radiotherapy and chemotherapy. The patient was then referred to surgery at the Wielkopolska Cancer Center in Poznań. After final exclusion of disease dissemination (by means of PET-CT) the patient underwent total gastrectomy with D2 lymphadenectomy, and gastrointestinal tract reconstruction by means of the Roux-en-Y method. The histopathological examination result was as follows: tubular-papillary G2 adenocarcinoma (intestinal type), pT2 pN0 (23 evaluated lymph nodes without cancer metastasis), vascular neoplastic emboli, and positive HER2 protein expression. After surgery the patient was subject to adjuvant chemotherapy. Control brain CT examinations revealed the presence of 4 recurrent metastatic lesions-the patient was disqualified from stereotactic radiation therapy and was subject to palliative chemotherapy. The discussion presented the problem of treating patients with stage IV gastric cancer, including current management guidelines, as well as literature review concerning the treatment of patients with diagnosed gastric cancer and brain metastases.
Źródło:
Polish Journal of Surgery; 2013, 85, 7; 401-406
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Total Laryngectomy for Treatment of T4 Laryngeal Cancer: Trends and Survival Outcomes
Autorzy:
Badwal, Jaspreet Singh
Powiązania:
https://bibliotekanauki.pl/articles/1391950.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
Total laryngectomy
laryngeal cancer
T4 laryngeal cancer
Opis:
Introduction: Management of advanced laryngeal cancer has shown fluctuating trends during the last few decades. Though many extensive reports are available in the literature regarding survival outcomes for advanced laryngeal cancer, there is a paucity of elaborate systematic reviews giving a complete picture of facts and figures. The present analysis brings to attention the most relevant data in a focused and up to date format, for simpler interpretation of evidence-based inference. Objective: To present the trends in the treatment of T4 laryngeal cancer over the past few decades and analyze survival outcomes for different treatment modalities in the management of T4 laryngeal cancer by way of systematic review. Methods : An electronic search was conducted using the terms “total laryngectomy”, “T4 laryngeal cancer”, “survival outcomes” in combination with the following search strategy : Search block Laryngeal cancer - "Laryngeal Neoplasms"[Mesh] OR ((Laryngeal[tiab] OR larynx[tiab] OR "Larynx"[Mesh]) AND (“Neoplasms”[Mesh] OR neoplasm* [tiab] OR tumor* [tiab] OR tumour* [tiab] OR cancer* [tiab] OR malignancy* [tiab] OR carcinoma* [tiab] OR neoplasm* [tiab] OR oncology* [tiab])); Search block Total laryngectomy - "Laryngectomy"[Mesh] OR total laryngectomy*[tiab] OR total laryngopharyngectomy*[tiab] OR total pharyngolaryngectomy*[tiab]; Search block T4 - t4[tiab]. Clinical studies were retrieved from the electronic databases of PubMed, EMBASE, SCOPUS and Cochrane Library. 304 articles had been published till June 2017, which included prospective studies, randomized controlled trials, retrospective studies, and smaller descriptive studies. References of the selected studies were further searched for relevant articles. Apart from this, a search was conducted on Google Scholar to obtain related articles. Results: Numerous studies, as mentioned in this review, provide authentic evidence in relation to the efficacy and outcome of surgical treatment for T4 laryngeal cancer. To address the problem of heterogeneity with regards to patient selection, numerous reports pertaining to T4 patients exclusively have been included. Conclusion: Total laryngectomy remains the gold standard for management of T4a laryngeal cancer. After the unparalleled oncological outcomes of more than a century, the technique has stood the test of time. An exhaustive review of the literature has been presented, discussing the trends in the treatment of advanced laryngeal cancer across different continents. However, it must be specified that the purpose of the study is not to prove one treatment protocol to be superior to the other but to bring out patterns of adherence to protocols and guidelines as suggested by multidisciplinary consensus reports and the consequent outcomes.
Źródło:
Polish Journal of Surgery; 2019, 91, 3; 30-37
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Young Patient Age as the Cause of Delayed Diagnosis of Gastrointestinal Carcinoma
Autorzy:
Zaręba, Konrad
Bandurski, Roman
Kędra, Bogusław
Powiązania:
https://bibliotekanauki.pl/articles/1396688.pdf
Data publikacji:
2012-06-01
Wydawca:
Index Copernicus International
Tematy:
pancreatic cancer
gastric cancer
colorectal cancer
young patient age
Opis:
Most patients diagnosed with gastrointestinal carcinomas are older people. The above-mentioned fact may lead to an erroneous finding that the problem does not concern patients aged between 20 and 30 years. Unfortunately, this assumption is often the reason for late diagnosis and delayed treatment of these malignancies. The study presented an example of three patients subject to surgical management of gastrointestinal carcinomas at the II Department of General and Gastroenterological Surgery, Medical University in Białystok.
Źródło:
Polish Journal of Surgery; 2012, 84, 6; 317-321
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Peritoneal carcinomatosis of colorectal cancer
Autorzy:
Jastrzębski, Tomasz
Zegarski, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1393356.pdf
Data publikacji:
2017
Wydawca:
Index Copernicus International
Tematy:
colorectal Cancer
peritoneal metastases
HIPEC
financial aspect
Opis:
The incidence of peritoneal carcinomatosis of colorectal cancer amounts to 5%-15% for synchronous metastases and as much as 40% in cases of local recurrence. Despite significant advances in pharmacological treatment consisting in the introduction of targeted medications, prognoses for patients with peritoneal metastases are still unfavorable. Mean survival of these patients undergoing palliative treatment is in the range of 6-9 months; overall survival rarely exceeds 2 years upon extensive chemotherapy. Markedly better results are obtained for cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC). This treatment offers much better outcomes, leading to 5-year survival rates of as much as 30%-50%. The possibility to achieve such outcomes depends on the staging of peritoneal metastases as well as the completeness of macroscopic cytoreduction. The procedures require significant experience in abdominal surgery, are time-consuming (mean duration of the procedure ranging from 6 to 8 hours) and are burdened by complications that are due not only to the procedure itself but also to the intraperitoneal administration of the cytostatic drug at elevated temperature (41.5 °C). However, in patients with metastases limited to the peritoneum, the procedure is justified by its outcomes. At the same time, a combination of surgical cytoreduction with HIPEC followed by systemic chemotherapy offers a radical change in prognosis for patients hitherto qualified for palliative treatment only.
Źródło:
Polish Journal of Surgery; 2017, 89, 5; 34-42
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment Of Plasma B-Catenin Concentration As Biomarker Of Thyroid Cancer*
Autorzy:
Bełdowski, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1395666.pdf
Data publikacji:
2015-07-01
Wydawca:
Index Copernicus International
Tematy:
beta-catenin
thyroid cancer
Opis:
New diagnostic methods for thyroid diseases are still being searched for. Immunohistochemical diagnosis is expanded by the introduction of new biomarkers including ß-catenin (B-Cat). Associations are indicated between the cellular expression of this biomarker and tumor stage, nodal metastases and the degree of tumor cell differentiation. Reports are scarce regarding the plasma level of this biomarker in malignant neoplastic diseases. The aim of the study was to analyze the plasma B-Cat concentration and the possibility of it use in the diagnostics of patients with nodular goiter and papillary thyroid carcinoma. Material and methods. Plasma B-Cat concentration was determined in 64 patients with goiter and 15 healthy volunteers. The final histopathological examination revealed 41 cases of papillary thyroid carcinoma (PTC) and 13 cases of nodular goiter (NG). Results. A significant increase in B-Cat (p <0.05) in both groups compared to the control group. No differences in the concentrations of biomarker was demonstrated between the PTC and NG groups. After determining the AUC for the tested biomarker, the B-Cat ratio of the area value 0.721 was the strong diagnostic test. Conclusions. Changes in the plasma B-Cat concentration can be the biomarker of thyroid cancer but it cannot be used for the detection of papillary thyroid carcinoma becouse of concomitant tumor-like lesions in the thyroid gland.
Źródło:
Polish Journal of Surgery; 2015, 87, 7; 340-345
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synchronous Gastric and Rectal Cancer in a 50 Year-Old Man – Case Report
Autorzy:
Pierko, Jacek
Łukaszewicz, Jerzy
Sawicka-Pierko, Anna
Hady, Hady Razak
Dadan, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1396903.pdf
Data publikacji:
2012-12-01
Wydawca:
Index Copernicus International
Tematy:
synchronous tumor
gastric cancer
colorectal cancer
Opis:
The occurrence of synchronous tumors of the gastrointestinal tract is rarely observed in general surgery, diagnosis is frequently incidental, often intraoperatively. The aim of this study was to present a case of a 50 year-old male patient admitted to the Department of Gastroenterology, University Hospital in Białystok, due to abdominal pain, significant weakness and excretion of tarry stools. Imaging diagnostics revealed the presence of a large gastric tumor (histopathological type - adenocarcinoma), and single metastasis to the liver. The patient was qualified for total gastrectomy. Surgery was performed at the 1st Department of General and Endocrinological Surgery, University Hospital in Białystok. Rectal cancer, which was observed during the operation was removed simultaneously.
Źródło:
Polish Journal of Surgery; 2012, 84, 11; 582-584
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synchronous Occurrence of Colon and Appendiceal Adenocarcinoma
Autorzy:
Goryń, Tomasz
Meszka, Monika
Pawlak, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1395731.pdf
Data publikacji:
2014-03-01
Wydawca:
Index Copernicus International
Tematy:
appendiceal cancer
synchronous tumors
colon cancer
Opis:
The study presented two cases of synchronous occurrence of colon and appendiceal adenocarcinoma. Both patients required surgical intervention, due to acute peritonitis during the course of acute appendicitis. In case of one patient we performed abdominal CT confirming the presence of sigmoid cancer. The patient was subjected to appendectomy and Hartmann’s operation. The second patient underwent an appendectomy, and colonoscopy performed two months later revealed the presence of rectal adenocarcinoma. The patient was subjected to low anterior rectal resection. The histopathological results considering both patients revealed the presence of synchronous colon and appendiceal adenocarcinoma.
Źródło:
Polish Journal of Surgery; 2014, 86, 3; 147-150
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of changes in body composition measured with bioelectrical impedance in patients operated for pancreatic, gastric and colorectal cancer
Autorzy:
Dzierżek, Przemysław
Kurnol, Krzysztof
Hap, Wojciech
Frejlich, Ewelina
Diakun, Agata
Karwowski, Adrian
Kotulski, Krzysztof
Rudno-Rudzińska, Julia
Kielan, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1391802.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
body composition
cioelectrical impedance
colorectal cancer
pancreatic cancer
stomach cancer
Opis:
ntroduction: A proper level of nutrition is significant in the period of convalescence in patients subject to major surgical procedures, particularly due to neoplastic disease. Bioelectrical Impedance Analysis, or BIA is a widely used method in assessing body mass composition. BIA measurement is easy, quick, cheap and repetitive. Material and methods: We assessed the body composition of 56 patients (25 women and 31 men) hospitalized and operated at the Department of General and Oncological Surgery of the Wroclaw Medical University in the years 2017–2018 using bioelectric impedance. Results: The average body weight loss in the 4th postoperative day was 1.32% of body mass and on the day of release from hospital – 4.23% of body mass in relation to body mass upon admission. The percentage of body fat (FM – Fat Mass) in patients admitted to the department is above the normal range. The change in body composition in hospitalized patients mainly concerns the amount of adipose tissue and the amount of extracellular and intracellular water (ECW – Extracellular Water; ICW – Intracellular Water). Conclusions: Bioelectrical impedance can be an easy and effective method of assessing body composition and its change in patients undergoing major surgery. Amongst the analyzed groups, patients operated for pancreatic cancer lose the largest percentage of body weight until discharge from the department. Loss of body mass mainly occurs as loss of fat mass (FM).
Źródło:
Polish Journal of Surgery; 2020, 92, 2; 8-11
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of the effects of mammography screening program on cancer progression and implemented treatment in patients with breast cancer
Autorzy:
Nowikiewicz, Tomasz
Zegarski, Wojciech
Piątkowska, Magdalena
Klag, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1396169.pdf
Data publikacji:
2013-04-01
Wydawca:
Index Copernicus International
Tematy:
brest cancer
staging
conserving treatment
mammography screening
Opis:
The primary goal of mammography screening is to decrease mortality in patients with breast cancer. The aim of the study was evaluation of the screening program results on course of implemented therapy and its results in breast carcinoma patients. Material and methods. Evidence includes data on the group of 1818 patients with breast cancer that were subject to surgical treatment at the Clinic of Breast Cancer and Reconstructive Surgery of the Oncology Center in Bydgoszcz (558 patients hospitalized from January 2006 to December 2006 and 1260 patients treated from January 2011 to June 2012). Analysis included type of diagnostic procedure implemented before surgical treatment, as well as grade of cancer progression, results of pathology tests done on specimens and type of surgical procedure. Additionally, the screening group (tumor diagnosed based on screening mammography) and symptomatic group (cancer diagnosed otherwise that within the screening program) were identified. Results. In 2006, in 28.4% of patients included in the study, primary tumor was discover in screening process (vs 61.5% in 2011-2012). In the first period, 35.7% of changes did not exceed 2 cm - cT1 (vs 48.3% in 2011-2012), while the percentage of cT4 was 9.9% (vs 4.7% in 2011-2012). In 2006, 30.8% of patients were treated in the grade I of clinical progression (vs 44.2% in 2011-2012), 53.4% in the grade II, 14% in grade III and 0.2% in grade IV (vs 45.7%, 9.7%, and 0.4%, respectively). In 45.5% (2006) and 39.9% (in 2011-2012) of patients, metastases were found in axillary lymph nodes. Differences were similar both in screening and symptomatic group. In 2006, in 12.4% of surgical patients breast conserving therapy (BCT) was implemented (vs 49.8% in 2011-2012). In the screening group, it was applied in 15.2% of patients (in 2006) and in 63% (in 2011- 2012), while in symptomatic group the percentages were 11.8% and 41%, respectively. Conclusions. In both periods of analysis, significant differences were observed as to implementation of breast cancer screening program, as well as to grade of clinical and pathological progression of the cancer. Observable increase of screening tests allowed for significantly more frequent implementation of breast conserving surgical procedures.
Źródło:
Polish Journal of Surgery; 2013, 85, 4; 204-209
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diabetes association of polyps and colon cancer
Autorzy:
Miłek, Tomasz
Forysiński, Karol
Myrcha, Piotr
Ciostek, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1392134.pdf
Data publikacji:
2019
Wydawca:
Index Copernicus International
Tematy:
colorectal cancer
colorectal polyps
diabetes mellitus
Opis:
Aim: The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes. Methods: In 2014–2015, 976 colonoscopies were performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group we documented the relationship between HbA1C and the occurrence of polyps with high-grade dysplasia, and colon cancer. The data were statistically analyzed. Results: 1. Patients with diabetes show a higher incidence of polyps with high-grade dysplasia/carcinoma – 32/91 (35.16%) in comparison to patients without diabetes – 136/885 (15.37%), P < 0.001; 2. Patients with diabetes show a higher incience of polyps with cancer – 9/91 (9.89%) as compared to patients without diabetes – 18/885 (2.03%), P < 0.001. 3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (P = 0.022). Conclusion: The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to a conclusion that diabetic patients are at a higher risk of developing colorectal cancer, thus are in higher need for controlled colonoscopy. Therefore, it may be worth considering a scheme for screening patients in the above-mentioned group with colonoscopy.
Źródło:
Polish Journal of Surgery; 2019, 91, 4; 9-12
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Metalloproteinase 2 and 9 Activity in the Development of Pancreatic Cancer
Autorzy:
Durlik, Marek
Gardian, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1396635.pdf
Data publikacji:
2012-08-01
Wydawca:
Index Copernicus International
Tematy:
pancreatic cancer
metalloproteinases
MMP
pancreatic tumor
Opis:
Pancreatic adenocarcinoma is the fourth most common cancer occurring in both women and men. In Poland, within the past ten years the number of deaths from pancreatic cancer increased by 29%.The aim of the study was to determine the correlation between the activity of metalloproteinase (MMP) 2 and 9 and progression and aggressiveness of pancreatic cancer.Material and methods. Tissue samples were collected from 36 patients with diagnosed pancreatic adenocarcinoma who underwent Whipple resection. Tumor tissues were analyzed by gel zymography, zymography in situ and immunohistochemistry.Results. The activity of MMPs was found mainly in cancer cells. Active form of MMP2 (62 kDa) was present in 88% of cases and MMP9 (83 kDa) in 38% of cases. By contrast, immunohistochemical staining revealed the presence of metalloproteinase 9 in all studied tissues. MMP activity was assessed against histological grade of the tumor. In the case of group G1 there was no activity of matrix metalloproteinase 9. By comparing the activity we concluded that the activity of MMPs in tumors with the highest degree of differentiation is significantly lower than in G2 and G3. Metalloproteinase 9 expression analysis revealed no significant differences between the groups of various degrees of histological maturity. The level of expression did not differ between the groups N0 and N1.Conclusion. Lack of metalloproteinase 9 activity in group G1 may indicate that MMP9 is activated only in higher tumor grades. We have shown that an active form of MMP2 is found in all histological grades, which supports its involvement in the development of pancreatic cancer. Metalloproteinases are attractive target of anticancer therapy but not only the level of expression of metalloproteinases should be taken into account but also their level of activity and factors associated with their activation.
Źródło:
Polish Journal of Surgery; 2012, 84, 8; 377-382
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between chest pain and level of perioperative anxiety in patients with lung cancer
Autorzy:
Malinowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1392739.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
perioperative anxiety
pain
lung cancer
Opis:
Introduction: Chest pain is one of the symptoms of lung cancer. Chest pain disrupts patient’s functioning in somatic and psychic area. Purpose: Whether the existence of chest pain affects the level of perioperative anxiety in lung cancer patients. Is there a relationship between everyday functioning due to the chest pain and the level of perioperative anxiety? Is there a relation between anxiety associated with pain and gender? What is the cause of anxiety in this group of the patiens? Methodology: The study was conducted among 150 patients with lung cancer before the scheduled surgery. Data was collected with the use of questionnaire assessment of perioperative anxiety level in patients with lung cancer. Results: The chest pain before the surgery was confirmed by 63 (42%) patients, in case of 87 (58%) patients it was not identified. Chest pain was in case of 48% women and 36% men. 50 (33,3%) research participants who experienced chest pain and 35 patients (23,3%) without this symptom declared experiencing perioperative anxiety. In patients with lung cancer, the correlation: between chest pain and perioperative anxiety was (Z = -4.67; p< .001); between the difficult daily functioning of pain and perioperative anxiety was (Z = -4.72; p< .001); between gender and perioperative anxiety associated with pain was (Z = -3.24; p = 001). Patients afraid of: pain (37,3%), breathing problems (24,0%), physical disability (16,0%), eating problems (12,0%) sleep disorders (9,3%), nothing (1,3%). Conclusions: Patients with chest pain exhibited significantly higher of perioperative anxiety levels than non-symptomatic patients, as well as higher anxiety levels due to deteriorated daily functioning caused by the disorder. Women had a higher level of anxiety associated with pain than men before the surgery. Patients with lung cancer were most afraid of pain in the perioperative period.
Źródło:
Polish Journal of Surgery; 2018, 90, 2; 23-27
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Local Antibiotic Therapy in Rectal Cancer Surgery
Autorzy:
Morawiec, Zbigniew
Pawlak, Mariusz
Kołacińska, Agnieszka
Dziki, Adam
Powiązania:
https://bibliotekanauki.pl/articles/1397022.pdf
Data publikacji:
2012-12-01
Wydawca:
Index Copernicus International
Tematy:
rectal cancer
infectious complications
local antibiotic use
Opis:
Infectious complications and their consequences are still key issues in rectal cancer surgery. Currently, intravenous antibiotic administration is a recognized method for lowering the rate of these complications. The aim of the study was to assess the efficacy of complementary application of a gentamicin-impregnated sponge in the perineal wound or in the vicinity of intestinal anastomosis after abdominoperineal resection or low anterior resection. Material and methods. 112 patients with primary rectal cancer were enrolled in this study. 42 patients were treated with a gentamicin sponge and drainage (group A) and 70 individuals were treated with drainage alone (group B). In the aforementioned groups a routine short-term regimen of antibiotic prophylaxis was used. We applied gentamicin-impregnated sponges in 27 patients in whom anterior resection was performed and in 15 patients from the abdominoperineal resection group (64% and 36%, respectively). In the control group, 44 anterior resections and 26 abdominoperineal resections were carried out (63% and 37%, respectively). Results. We did not observe statistically significant differences in the incidence of suppurative complications (intraabdominal abscess, perineal wound infection): 4 cases (9.52%) in group A and 9 (12.58%) in group B and anastomotic leakage with clinical manifestation after low anterior resection: 1 case (3.7%) in group A and 2 (4.5%) in group B. Postoperative fever of unknown origin was noted more often in group B: 23 patients (32.8%) versus 10 patients (23.8%) in group A and this difference was statistically significant (p<0.05). Hospitalization after surgery was also significantly longer in group B (9-37 days, median 11 days) as compared with group A (8-26 days, median 13 days) (p<0.05). Conclusions. Local antibiotic therapy in rectal cancer surgery lowered the incidence of postoperative fever of unknown origin and permitted shorter hospitalization after surgery. Local gentamicin application in rectal cancer surgery did not change significantly the rate of infectious complications.
Źródło:
Polish Journal of Surgery; 2012, 84, 12; 613-617
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical treatment of pancreatic cancer
Autorzy:
Masiak-Segit, Wioletta
Rawicz-Pruszyński, Karol
Skórzewska, Magdalena
Polkowski, Wojciech P
Powiązania:
https://bibliotekanauki.pl/articles/1392748.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
pancreatic cancer
pancreatoduodenectomy
distal pancreatic resection
Opis:
The only way to cure the patient with adenocarcinoma of the pancreas (RT) is surgical excision of the tumor. The standard surgical treatment of resectable pancreatic carcinoma is considered the classic pancreatoduodenectomy (PD) with the Kausch-Whipple procedure, or the pylorus-preserving PD with the Traverso-Longmire method. The most difficult technically and at the same time the most important PD stage from an oncological point of view is the separation of the head of the pancreas from the superior mesenteric artery. Over the last decades several PD modifications have been developed, focusing on this maneuver in the early phase of the operation, i.e. before the pancreas is cut (an irreversible stage of the procedure). These procedures in the English literature are called “artery-first approach” or “SMA-first approach”. The term “mesopancreas” was created. Complete removal of the mesopancreas together with the proximal part of the jejunum is considered an R0 resection in the case of a tumor of the head of the pancreas with direct or indirect vascular invasion, or metastases to regional lymph nodes, and in English literature it is referred to as pancreatoduodenectomy with systematic mesopancreas dissection (SMDPD). Distal resection of the pancreas (DRT) due to cancer, is associated with a high percentage of positive margins, insufficient number of removed lymph nodes, low survival rates. A new technique was developed - a radical proximal-distal modular pancreatosplenectomy (RAMPS). In RAMPS, surgical operations proceed from the side of the pancreas head towards the tail, the pancreas is cut early, and the splenectomy is performed at the final stages of the procedure. Currently, following the PD model, attempts are made to further modify the original RAMPS technique, especially in the direction of SMA-first approach. In patients with borderline resectable pancreatic tumors or locally advanced tumors, after neoadjuvant treatment, a technique of radical resection with preservance of arterial vessels - “the TRIANGLE operation” has been elaborated. Despite the tremendous progress of surgical techniques, RT is still detected too late in the phase preventing effective resection.
Źródło:
Polish Journal of Surgery; 2018, 90, 2; 45-53
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 139

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