Wszystkie pola: cancers - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Updated National Comprehensive Cancer Network guidelines for treatment of head and neck cancers 2010-2017
Autorzy:: Wierzbicka, Małgorzata
Napierała, Joanna
Powiązania:: https://bibliotekanauki.pl/articles/1398501.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: head and neck cancers treatment guidelines
biological therapy
personalized treatment
recommendations
Opis:: Introduction: The diagnostic and therapeutic recommendations have been changing over the years to improve treatment outcomes and quality of life of Head and Neck Cancer (HNC) patients. Aim: The aim of this study was to present currently recommended Head and Neck Cancer treatment guidelines based on the literature review with particular emphasis on novel approaches the NCCN algorithms. Material and methods: The review of literature covering articles published in the last five years and pointing out essential changes in HNC treatment regarding evidence based medicine. The study focused on the analysis of novel approaches for the particular primaries, the implementation of biological therapies and personalized cancer therapies. Results: Updates in the oncological NCCN guidelines for all ENT primaries except major salivary glands and subglottis are based on knowledge derived from the basic sciences, clinical trials and the best evidence available currently. The latest recommendations emphasize value of biological therapies use.
Źródło:: Polish Journal of Otolaryngology; 2017, 71, 6; 1-6
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Retrospective evaluation of risk factors for oral cavity and oropharynx cancers in patients under the program of head and neck cancers prevention
Autorzy:: Kowalski, Andrzej
Olszewski, Jurek
Zielińska-Bliźniewska, Hanna
Powiązania:: https://bibliotekanauki.pl/articles/1397748.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: Head and Neck Cancer Prophylaxis Program
oral cavity
oropharynx cancer
risk factors
Opis:: Introduction: The aim of the study was to analyze the risk factors for oral cavity and pharyngeal cancer in people examined under the Head and Neck Cancer Prophylaxis Program. Material and methods: The study was conducted in a total of 300 patients, including 186 women and 114 men, as part of the Head and Neck Cancer Prevention Program in 2014–2018. Before the laryngological examination, the patients completed a demographic and medical questionnaire regarding the risk factors of head and neck cancer, including education, reported disease symptoms, smoking addiction, number of cigarettes smoked daily, alcohol consumption, frequency of visits in a dental office, oral hygiene measures, number of sexual partners, oral sex, family medical history of head and neck cancer. Results: The subjects reported the following symptoms: hoarseness 43.33%, difficulty swallowing 21.33%, pain or mouth burning 20.33% and other symptoms were observed in 46.33%. The main dental symptoms were: bleeding from the gums during teeth brushing in 48.89%, dry mouth 45.56%. Currently 20.33% of respondents smoke, whereas 54% of patients smoked in the past. In the analyzed material, the majority (80%) consumed alcoholic beverages. 27.67% of respondents admitted having oral sex, including 24.73% of women and 32.46% of men. After performing the extended diagnostics, the tumor was found in 10% of the subjects. C onclusions: Statistical significance of differences was found: between hoarseness and alcohol consumption, both in women and in men, between hoarseness and smoking in women, between difficulty in swallowing and smoking in women, between burning/pain in the mouth and smoking in men, between hoarseness and the cultivation of oral sex in men, between the difficulty of swallowing and the practice of oral sex in the studied men and between burning/pain in the oral cavity and the occurrence of malignancy.
Źródło:: Polish Journal of Otolaryngology; 2019, 73, 6; 24-31
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The predictive value of videostroboscopy in the assessment of premalignant lesions and early glottis cancers
Autorzy:: Rzepakowska, Anna
Sielska-Badurek, Ewelina
Osuch-Wójcikiewicz, Ewa
Sobol, Maria
Niemczyk, Kazimierz
Powiązania:: https://bibliotekanauki.pl/articles/1398516.pdf
Data publikacji:: 2017
Wydawca:: Index Copernicus International
Tematy:: laryngovideostroboscopy
precancerous lesions
larynx
glottis
early glottic cancer
Opis:: Objective: To assess the sensitivity and specificity of larngovideostroboscopy (LVS) in the diagnosis of precancerous and malignant lesions of the vocal folds. Material and methods: In 175 patients (128 men and 47 women), aged 19-88 years, mean age 61.5, who were admitted to the clinic with diagnosed premalignant conditions of vocal fold mucosa (leukoplakia, chronic hypertrophic inflammatory lesions) and thickening or tumor on the vocal fold, there was performed LVS before the laryngeal microsurgery. The LVS study included: localization of the leasion, movement of the vocal folds, mucosal wave, shape of glottis clousure, amplitude and symmetry of vocal fold vibration. In the evaluation, a point scale was applied for the individual functional parameters. The scale ranged from 0 to 14. Patients with impaired vocal fold motion or absent mucosal wave were positive on LVS for malignant lesions. Those with limitted mucosal wave were positive on LVS for dysplastic lesions. The results were compared with the final histopathological examination and the sensitivity, specificity, accuracy, positive (PPV) and negative (NPV) predictive value were calculated. Results: On the basis of histopathological examination, benign lesions (normal or inflammatory mucosa) accounted for 20% of diagnoses, hypertrophy and parakeratosis for 28%, low and middle grade dysplasia accounted for 10% and malignant lesions (high-grade dysplasia, pre-invasive cancer, Invasive cancer) was diagnosed in 42% of patients. The overall mean score for LVS was 4.5 and 8.0, respectively for benign and malignant lesions. Sensitivity, specificity, accuracy, PPV and NPV of LVS in detecting malignant lesions were respectively - 95.6%, 23.8%, 61.1%, 57.6% and 83.3% and in detecting both premalignant and malignant lesions were respectively – 90.7%, 31.4%, 78.9%, 84.1% and 45.8%. Conclusions: Because of the high sensitivity of LVS in detecting precancerous and malignant lesions, this method is a very good tool for screening of pathology within the larynx.
Źródło:: Polish Journal of Otolaryngology; 2017, 71, 4; 14-18
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Gender-related incidence, risk factors exposure and survival rates of laryngeal cancers – the 10-years analysis of trends from one institution
Autorzy:: Majszyk, Daniel
Bruzgielewicz, Antoni
Osuch-Wójcikiewicz, Ewa
Rzepakowska, Anna
Niemczyk, Kazimierz
Powiązania:: https://bibliotekanauki.pl/articles/1397790.pdf
Data publikacji:: 2019
Wydawca:: Index Copernicus International
Tematy:: laryngeal cancer
epidemiology
men and women
risk factors
Opis:: Objectives: The aim of the study was the analysis of the epidemiology of laryngeal cancer over 10 years in relation to known risk factors and to assess the current survival rates in this group of patients. Methods: The data were retrospectively collected from patients’ medical records, then entered in the database using dedicated software and a statistical analysis was performed. Results: 512 subjects - 443 men (86.5%) and 69 women (13.5%) were enrolled into the study. The male-to-female ratio was 6.4:1. There were 97.1% smoking women and 98% smoking men, however the history of more than 20 cigarettes per day smoking admitted 81.1 % of women and 94.6% of men. Heavy alcohol consumption was the case in 14 (20.3%) women and in 307 (69.3%) men. For both the size of heavy alcohol consumption and the size of excessive tobacco use, there was found statistically significant difference between women and men with laryngeal cancer (p<0.05). In the majority of male and female subjects, the tumour was located in the supraglottis/glottis area. Apparently this tumour location was much more common among women, accounting for 60.9% of cases , while in men was confirmed in 39.3% of cases. The stages of the laryngeal cancer were similarly of high advancement for both the men and women - stages III and IV were confirmed in 82.6% of women and in 77.6% of men. The over 5-year survival rate was 39.1% among women and 37.2% among men. Conclusions Contradictory to decreased exposure to risk factors and the shorter period for diagnosis, the higher stages of cancer were observed in women. Although in women the advancement was higher and the majority of cases were located in unfavourable supraglottic area, the survival rates were higher. Key words: laryngeal cancer, epidemiology, men and women, risk factors
Źródło:: Polish Journal of Otolaryngology; 2019, 73, 3; 6-10
0030-6657
2300-8423
Pojawia się w:: Polish Journal of Otolaryngology
Dostawca treści:: Biblioteka Nauki

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