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Wyświetlanie 1-2 z 2
Tytuł:
Modelling the effects of lung cancer motion due to respiration
Autorzy:
Adamczyk, Marta
Adamczyk, Sebastian
Piotrowski, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/148246.pdf
Data publikacji:
2020
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
dosimetric plan verification
external beam radiation therapy
lung cancer
respiratory motion
Opis:
Background and objectives: To justify the concept of validating conformal versus intensity-modulated approach in the treatment of non-small cell lung cancer (NSCLC). Materials and methods: For 10 patients representative of the spectrum of tumour sizes and locations, two plans were prepared: one with three-dimensional conformal radiation therapy (3DCRT) technique and the other with intensity-modulated radiation therapy (IMRT) technique. Preliminary measurements were performed in static conditions. For each of the fi eld angles considered, the motion kernel was generated to simulate tumour motion trajectories, with the largest amplitude in the cranio-caudal direction of 4, 6, and 8 mm. The measurement results determined the agreement between the planned and measured doses. Results: No statistically signifi cant differences were found between the motion patterns, with the smallest amplitudes for clinical target volume in 3DCRT. For IMRT, the signifi cant differences between 0 mm vs. 6 mm and 0 mm vs. 8 mm amplitudes were found. The motion impact on delivered vs. planned doses had less effect on the oesophagus in 3DCRT compared to that in IMRT. The observed differences were comparable for the heart. Interpretation and conclusions: For maximal amplitudes below 4 mm, the disagreement between planned and delivered doses can be neglected. However, the amplitudes above 5 mm and 7 mm lead to signifi cant changes in IMRT and 3DCRT dose distribution, respectively.
Źródło:
Nukleonika; 2020, 65, 4; 95-103
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evolution of treatment planning and dose delivery methods during radiotherapy for patients undergoing bone marrow transplantation : a review
Autorzy:
Litoborska, Joanna
Piotrowski, Tomasz
Jodda, Agata
Malicki, Julian
Powiązania:
https://bibliotekanauki.pl/articles/147607.pdf
Data publikacji:
2020
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
total body irradiation
total marrow irradiation
TBI/TMI planning
TBI/TMI dose delivery
Opis:
Background and objectives: This study describes the treatment planning and dose delivery methods of radiotherapy for patients undergoing bone marrow transplantation. The analysis was carried out in the context of the evolution of these methods over the last 60 years. Materials and methods: A systematic literature search was carried out using the PubMed search engine. Overall, 90 relevant studies were included: 24 general studies, 10 describing isotopes usage, 24 related to conventional and 32 to advanced methods. Results: The analysis of the evolution of radiotherapy methods shows how signifi cantly the precision of dose planning methods and its delivery have changed. The atypical positioning caused by geometrical requirements for applications of isotopes or conventional techniques has been replaced by positioning on a therapeutic couch, which allows a more precise setup of the patient that is necessary for an exact delivery of the planned dose. The dose can be fully optimized and calculated on tomographic images by algorithms implemented in planning systems. Optimization process allows to reduce doses in organs at risk. The accuracy between planned and delivered doses can be checked by pretreatment verifi cation methods, and the patient positioning can be checked by image guidance procedures. Interpretation and conclusions: Current radiotherapy solutions allow a precise delivery of doses to the planning target volume while reducing doses to organs at risk. Nevertheless, it should be kept in mind that establishing radiotherapy as an important element of the whole therapeutic regimen resulted from the follow-up of patients treated by conventional techniques. To confi rm the clinical value of new advanced techniques, clinical trials are required.
Źródło:
Nukleonika; 2020, 65, 1; 19-30
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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