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Wyświetlanie 1-2 z 2
Tytuł:
Management of medical and psychosocial consequences of a radiological or nuclear terrorist event
Autorzy:
Janiak, M. K.
Powiązania:
https://bibliotekanauki.pl/articles/148757.pdf
Data publikacji:
2010
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
radiological/nuclear event
medical and psychosocial consequences
management
Opis:
Medical, psychological, and social consequences of a terrorist event involving the release of ionizing radiation will differ significantly from attacks with “classical” explosives. Victims of a detonation of a “dirty bomb” or a nuclear device can actually or allegedly absorb various doses of radiation and should be viewed as radiologically contaminated patients. Hence, both first responders and medical personnel should behave and act accordingly. General rules, guidelines, and procedures are described that should be implemented at all levels of medical management from the on-site emergency care until admittance to and treatment of the victims at a specialist hospital ward. The causes, manifestations and management of psychosocial sequelae of radiological terrorist incidents are also discussed.
Źródło:
Nukleonika; 2010, 55, 3; 393-399
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modulation of the growth of pulmonary tumour colonies in mice after single or fractionated low-level irradiations with X-rays
Autorzy:
Nowosielska, E. M.
Cheda, A.
Wrembel-Wargocka, J.
Janiak, M. K.
Powiązania:
https://bibliotekanauki.pl/articles/147682.pdf
Data publikacji:
2008
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
low-level X-rays
NK cells
macrophages
tumour colonies
anti-neoplastic activity
Opis:
A number of epidemiological and experimental data indicate that exposures to low doses of low-LET ionizing radiation may trigger the activity of natural anti-tumour immune mechanisms and inhibit tumour growth. Natural killer (NK) cells and activated macrophages play important roles in the anti-tumour defence of the host. In view of this, the aim of the present study was to correlate the tumour-inhibitory effect of low doses of X-rays with the activities of NK cells and macrophages. BALB/c mice were whole-body irradiated with single or fractionated doses of 0.1, 0.2, or 1.0 Gy X-rays and then intravenously injected with L1 sarcoma cells; 14 days later, tumour colonies on the lungs' surface were counted. Cytotoxic activities of NK cells and macrophages were estimated using the 51Cr-release and [3H]thymidineuptake assays, respectively. The anti-asialo GM1 antibody and carrageenan (CGN) were intraperitoneally injected to block the NK cell- and macrophage-mediated activities in vivo, respectively. Single and fractionated whole-body irradiation (WBI) of mice with 0.1 or 0.2 Gy X-rays led to reduction in the number of the pulmonary tumour colonies accompanied by the enhanced cytotoxic activities of both NK lymphocytes and macrophages. Treatment of mice with anti-asialo GM1 antibody or CGN abrogated the tumour-inhibitory effects of the low-level exposures to X-rays. The obtained data suggest that suppression of the development of pulmonary tumour colonies by single or fractionated irradiations of mice with the low doses of X-rays may result from stimulation of the natural anti-tumour defence reactions mediated by NK cells and/or cytotoxic macrophages.
Źródło:
Nukleonika; 2008, 53, suppl. 1; 9-15
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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